Impact of Digital Mammography on Cancer Detection and Recall Rates: 11.3 Million Screening Episodes in the English National Health Service Breast Cancer Screening Program.


:Purpose To report the impact of changing from screen-film mammography to digital mammography (DM) in a large organized national screening program. Materials and Methods A retrospective analysis of prospectively collected annual screening data from 2009-2010 to 2015-2016 for the 80 facilities of the English National Health Service Breast Cancer Screening Program, together with estimates of DM usage for three time periods, enabled the effect of DM to be measured in a study of 11.3 million screening episodes in women aged 45-70 years (mean age, 59 years). Regression models were used to estimate percentage and absolute change in detection rates due to DM. Results The overall cancer detection rate was 14% greater with DM (P < .001). There were higher rates of detection of grade 1 and 2 invasive cancers (both ductal and lobular), but no change in the detection of grade 3 invasive cancers. The recall rate was almost unchanged by the introduction of DM. At prevalent (first) screening episodes for women aged 45-52 years, DM increased the overall detection rate by 19% (P < .001) and for incident screening episodes in women aged 53-70 years by 13% (P < .001). Conclusion The overall cancer detection rate was 14% greater with digital mammography with no change in recall rates and without confounding by changes in other factors. There was a substantially higher detection of grade 1 and grade 2 invasive cancers, including both ductal and lobular cancers, but no change in the detection of grade 3 invasive cancers. © RSNA, 2018 Online supplemental material is available for this article. See also the editorial by C.I. Lee and J.M. Lee in this issue.






Blanks RG,Wallis MG,Alison R,Kearins O,Jenkins J,Patnick J,Given-Wilson RM




Has Abstract


2019-03-01 00:00:00












  • Pulmonary nodules at chest CT: effect of computer-aided diagnosis on radiologists' detection performance.

    abstract:PURPOSE:To evaluate the effect of computer-aided diagnosis (CAD) on radiologists' detection of pulmonary nodules. MATERIALS AND METHODS:Fifty chest computed tomographic (CT) examination cases were used. The mean nodule size was 0.81 cm +/- 0.60 (SD) (range, 0.3-2.9 cm). Alternative free-response receiver operating cha...


    pub_type: 杂志文章


    authors: Awai K,Murao K,Ozawa A,Komi M,Hayakawa H,Hori S,Nishimura Y

    更新日期:2004-02-01 00:00:00

  • Accuracy of fat-suppressed three-dimensional spoiled gradient-echo FLASH MR imaging in the detection of patellofemoral articular cartilage abnormalities.

    abstract:PURPOSE:To determine the accuracy of T1-weighted fat-suppressed (FS) three-dimensional (3D) fast low-angle shot (FLASH) magnetic resonance (MR) imaging for the detection of articular cartilage abnormalities of the patellofemoral joint. MATERIALS AND METHODS:Forty-one patients with suspected internal derangement of the...


    pub_type: 杂志文章


    authors: Recht MP,Piraino DW,Paletta GA,Schils JP,Belhobek GH

    更新日期:1996-01-01 00:00:00

  • Mesial temporal sclerosis: diagnosis with fluid-attenuated inversion-recovery versus spin-echo MR imaging.

    abstract:PURPOSE:To compare the accuracy of a fluid-attenuated inversion-recovery (FLAIR) sequence with that of a conventional double spin-echo (SE) sequence in the identification of increased signal intensity of the hippocampus in mesial temporal sclerosis (MTS). MATERIALS AND METHODS:Three blinded reviewers independently gra...


    pub_type: 杂志文章


    authors: Jack CR Jr,Rydberg CH,Krecke KN,Trenerry MR,Parisi JE,Rydberg JN,Cascino GD,Riederer SJ

    更新日期:1996-05-01 00:00:00

  • Endometrial Carcinoma: MR Imaging-based Texture Model for Preoperative Risk Stratification-A Preliminary Analysis.

    abstract::Purpose To evaluate the associations among mathematical modeling with the use of magnetic resonance (MR) imaging-based texture features and deep myometrial invasion (DMI), lymphovascular space invasion (LVSI), and histologic high-grade endometrial carcinoma. Materials and Methods Institutional review board approval wa...


    pub_type: 杂志文章


    authors: Ueno Y,Forghani B,Forghani R,Dohan A,Zeng XZ,Chamming's F,Arseneau J,Fu L,Gilbert L,Gallix B,Reinhold C

    更新日期:2017-09-01 00:00:00

  • Suspicious breast lesions: assessment of 3D Doppler US indexes for classification in a test population and fourfold cross-validation scheme.

    abstract:PURPOSE:To assess the diagnostic performance of various Doppler ultrasonographic (US) vascularity measures in conjunction with grayscale (GS) criteria in differentiating benign from malignant breast masses, by using histologic findings as the reference standard. MATERIALS AND METHODS:Institutional Review Board and HIP...


    pub_type: 杂志文章


    authors: LeCarpentier GL,Roubidoux MA,Fowlkes JB,Krücker JF,Hunt KA,Paramagul C,Johnson TD,Thorson NJ,Engle KD,Carson PL

    更新日期:2008-11-01 00:00:00

  • Effect of a legislative mandate on mammography use and coding practices in Maryland.

    abstract:PURPOSE:To analyze the effect of the 1991 Maryland legislative mandate of screening mammography benefits. MATERIALS AND METHODS:Claims submitted between January 1991 and December 1993 for outpatient mammograms obtained in women covered under Blue Cross Blue Shield of Maryland insurance indemnity contracts were analyze...


    pub_type: 杂志文章


    authors: Dans PE,Wright AT

    更新日期:1996-03-01 00:00:00

  • Acute stroke: evaluation with serial proton MR spectroscopic imaging.

    abstract:PURPOSE:To investigate the evolution of metabolic changes detectable with proton magnetic resonance (MR) spectroscopic imaging in acute stroke and to compare these findings with those of conventional MR imaging. MATERIALS AND METHODS:A patient with middle cerebral artery stroke underwent conventional proton-density (P...


    pub_type: 杂志文章


    authors: Barker PB,Gillard JH,van Zijl PC,Soher BJ,Hanley DF,Agildere AM,Oppenheimer SM,Bryan RN

    更新日期:1994-09-01 00:00:00

  • Adult and neonatal human brain: diffusional anisotropy and myelination with diffusion-weighted MR imaging.

    abstract::Diffusional anisotropy of human brain was investigated clinically in six adult volunteers, eight premature neonates, and three infants aged 5-10 months. Diffusion-weighted magnetic resonance imaging was performed with gradient b of 450 sec/mm2. The direction of diffusion-sensitive gradients was changed among x, y, and...


    pub_type: 杂志文章


    authors: Sakuma H,Nomura Y,Takeda K,Tagami T,Nakagawa T,Tamagawa Y,Ishii Y,Tsukamoto T

    更新日期:1991-07-01 00:00:00

  • Biliary tract depiction in living potential liver donors: comparison of conventional MR, mangafodipir trisodium-enhanced excretory MR, and multi-detector row CT cholangiography--initial experience.

    abstract:PURPOSE:To compare biliary tract depiction in living potential liver donors at conventional magnetic resonance (MR), mangafodipir trisodium-enhanced excretory MR, and multi-detector row computed tomographic (CT) cholangiography. MATERIALS AND METHODS:Eight living potential liver donors underwent iodipamide meglumine-e...


    pub_type: 杂志文章


    authors: Yeh BM,Breiman RS,Taouli B,Qayyum A,Roberts JP,Coakley FV

    更新日期:2004-03-01 00:00:00

  • Duplex carotid sonography: criteria for stenosis, accuracy, and pitfalls.

    abstract::Both carotid bifurcations were examined in 353 patients over a 20-month interval using a combination of real-time and pulsed Doppler ultrasound (duplex scanning). Angiographic correlation was available in 72 cases. Stenosis of the internal carotid was evaluated using a Doppler input frequency of 5 MHz and a scan angle...


    pub_type: 杂志文章


    authors: Jacobs NM,Grant EG,Schellinger D,Byrd MC,Richardson JD,Cohan SL

    更新日期:1985-02-01 00:00:00

  • Coronary artery calcification detected with ultrafast CT as an indication of coronary artery disease.

    abstract::To assess the relationship of coronary artery calcification to angiographically detectable disease, the authors evaluated 100 patients less than 60 years of age who underwent clinically indicated coronary angiography and ultrafast computed tomography (CT). The ultrafast CT technique consisted of 3-mm-thick contiguous ...


    pub_type: 杂志文章


    authors: Breen JF,Sheedy PF 2nd,Schwartz RS,Stanson AW,Kaufmann RB,Moll PP,Rumberger JA

    更新日期:1992-11-01 00:00:00

  • Molecular MR Imaging of Myeloperoxidase Distinguishes Steatosis from Steatohepatitis in Nonalcoholic Fatty Liver Disease.

    abstract::Purpose To test whether MPO-Gd, an activatable molecular magnetic resonance (MR) imaging agent specific for myeloperoxidase (MPO) activity, could detect MPO activity in nonalcoholic steatohepatitis (NASH) mouse models and human liver biopsy samples. Materials and Methods In this study, 20 leptin receptor-deficient and...


    pub_type: 杂志文章


    authors: Pulli B,Wojtkiewicz G,Iwamoto Y,Ali M,Zeller MW,Bure L,Wang C,Choi Y,Masia R,Guimaraes AR,Corey KE,Chen JW

    更新日期:2017-08-01 00:00:00

  • The interface sign: a computed tomographic sign for distinguishing pleural and intra-abdominal fluid.

    abstract::On computed tomographic scans of the upper abdomen the interface sign can help distinguish pleural and intra-abdominal fluid readily and accurately. A hazy interface between the fluid and liver or spleen is characteristic of pleural fluid. A sharp interface is characteristic of ascites. The interface sign has proved t...


    pub_type: 杂志文章


    authors: Teplick JG,Teplick SK,Goodman L,Haskin ME

    更新日期:1982-07-01 00:00:00

  • Movable core guide wire: evaluation of improved model.

    abstract::Six commercially available movable core guide wires were compared with each other and with a new design in glass models simulating tortuous vessels. The results demonstrate a wide variability in performance of the commercially available wires and the superiority of the new design. ...


    pub_type: 杂志文章


    authors: Smith TP,Derauf BJ,Darcy MD,Hunter DW,Castaneda-Zuniga WR,Amplatz K

    更新日期:1986-05-01 00:00:00

  • Irreversible JPEG compression of digital chest radiographs for primary interpretation: assessment of visually lossless threshold.

    abstract:PURPOSE:To determine if digital chest images could be compressed in a primary interpretation context without perceived loss of fidelity (below the visually lossless threshold) at transilluminated film or cathode ray tube (CRT) display. MATERIALS AND METHODS:One hundred forty-four posteroanterior radiographs were obtai...


    pub_type: 杂志文章


    authors: Slone RM,Muka E,Pilgram TK

    更新日期:2003-08-01 00:00:00

  • Thoracic actinomycosis: CT findings in eight patients.

    abstract::The chest radiographs and computed tomographic (CT) scans obtained in eight patients with pathologically proved cases of thoracic actinomycosis were independently reviewed by two observers. All patients were alcoholic men aged 42-62 years. Air-space consolidation, seen on the radiograph and CT scan in each case, was p...


    pub_type: 杂志文章


    authors: Kwong JS,Müller NL,Godwin JD,Aberle D,Grymaloski MR

    更新日期:1992-04-01 00:00:00

  • Early diagnosis of ovarian carcinoma: is a solution in sight?

    abstract:UNLABELLED:Ovarian cancer is the most lethal of the gynecologic malignancies. Because ovarian cancer symptoms are subtle and nonspecific, the diagnosis is often delayed until the disease is well advanced. Overall 5-year survival is a rather dismal 50% but can be improved to greater than 90% if the disease is confined t...


    pub_type: 杂志文章,评审


    authors: Lutz AM,Willmann JK,Drescher CW,Ray P,Cochran FV,Urban N,Gambhir SS

    更新日期:2011-05-01 00:00:00

  • The cathartic colon: pathological findings and radiological/pathological correlation.

    abstract::Cathartic colon has been described radiologically, but the pathological characteristics have not been reported. The authors describe a case in which radiological/pathological correlation was possible, with emphasis on the pathology of the colon. The disease simulates chronic ulcerative colitis radiologically and patho...


    pub_type: 杂志文章


    authors: Urso FP,Urso MJ,Lee CH

    更新日期:1975-09-01 00:00:00

  • Deep venous thrombosis: longitudinal study with duplex US.

    abstract::Forty-nine patients with deep venous thrombosis (DVT) of the lower limb were studied with repeated duplex ultrasound (US) for at least 1 year or until the vein became normal at US. Standard anticoagulant therapy was given for 3 months. In 36 patients, the veins became normal within 1 year. The likelihood of normalizat...


    pub_type: 杂志文章


    authors: Mantoni M

    更新日期:1991-04-01 00:00:00

  • Shear-wave elastography of the breast: value of a quality measure and comparison with strain elastography.

    abstract:PURPOSE:To determine whether addition of quality measure (QM) of shear-wave (SW) velocity (Vs) estimation can increase SW elastography sensitivity for breast cancer. MATERIALS AND METHODS:With written informed consent, this institutional review board-approved, HIPAA-compliant study included 143 women (mean age, 48.5 y...


    pub_type: 杂志文章


    authors: Barr RG,Zhang Z

    更新日期:2015-04-01 00:00:00

  • PET evaluation of soft-tissue masses with fluorine-18 fluoro-2-deoxy-D-glucose.

    abstract::Positron emission tomography (PET) with fluorine-18 fluoro-2-deoxy-D-glucose (FDG) was performed in 19 patients referred for clinical evaluation of soft-tissue masses. These patients had 20 different lesions and had been evaluated previously with computed tomography (CT) and/or magnetic resonance (MR) imaging. The dia...


    pub_type: 杂志文章


    authors: Griffeth LK,Dehdashti F,McGuire AH,McGuire DJ,Perry DJ,Moerlein SM,Siegel BA

    更新日期:1992-01-01 00:00:00

  • In-Bore 3-T MR-guided Transrectal Targeted Prostate Biopsy: Prostate Imaging Reporting and Data System Version 2-based Diagnostic Performance for Detection of Prostate Cancer.

    abstract::Purpose To determine the diagnostic yield of in-bore 3-T magnetic resonance (MR) imaging-guided prostate biopsy and stratify performance according to Prostate Imaging Reporting and Data System (PI-RADS) versions 1 and 2. Materials and Methods This study was HIPAA compliant and institution review board approved. In-bor...


    pub_type: 杂志文章


    authors: Tan N,Lin WC,Khoshnoodi P,Asvadi NH,Yoshida J,Margolis DJ,Lu DS,Wu H,Sung KH,Lu DY,Huang J,Raman SS

    更新日期:2017-04-01 00:00:00

  • Monocyte and/or macrophage infiltration of heart after myocardial infarction: MR imaging by using T1-shortening liposomes.

    abstract:PURPOSE:To test the hypothesis that magnetic resonance (MR) imaging R1 (R1 = 1/T1) mapping after selectively labeling monocytes with a T1-shortening contrast agent in vivo would enable the quantitative measurement of their spatiotemporal kinetics in the setting of infarct healing. MATERIALS AND METHODS:All procedures ...


    pub_type: 杂志文章


    authors: Naresh NK,Xu Y,Klibanov AL,Vandsburger MH,Meyer CH,Leor J,Kramer CM,French BA,Epstein FH

    更新日期:2012-08-01 00:00:00

  • Hypertension associated with massive, bilateral, posture-dependent renal dysfunction.

    abstract::Hippurate function scintiscans were obtained in prone and standing positions in a group of 76 patients with concurrent hypertension and nephroptosis. TWelve of these patients had massive, bilateral disturbance of intrarenal hippurate transport in the standing position; hippurate transport was normal in the prone posit...


    pub_type: 杂志文章


    authors: Clorius JH,Schmidlin P,Raptou E,Huber W,Georgi P

    更新日期:1981-07-01 00:00:00

  • Magnetization transfer contrast-prepared MR imaging of the liver: inability to distinguish healthy from cirrhotic liver.

    abstract:PURPOSE:To evaluate the ability of magnetization transfer (MT) contrast-prepared magnetic resonance (MR) imaging to help distinguish healthy from cirrhotic liver by using a spectrum of MT pulse frequency offsets. MATERIALS AND METHODS:This HIPAA-compliant prospective study was approved by the institutional review boar...


    pub_type: 杂志文章


    authors: Rosenkrantz AB,Storey P,Gilet AG,Niver BE,Babb JS,Hajdu CH,Lee VS

    更新日期:2012-01-01 00:00:00

  • Conventional and rapid MR imaging of the liver with Gd-DTPA.

    abstract::Twenty-three patients with malignant hepatic tumors underwent magnetic resonance (MR) imaging before and after intravenous administration of gadolinium-diethylene-triaminepentaacetic acid (DTPA). Two different doses were used, 0.1 mmol/kg and 0.2 mmol/kg. The larger dose proved to be more effective than the smaller do...


    pub_type: 杂志文章


    authors: Hamm B,Wolf KJ,Felix R

    更新日期:1987-08-01 00:00:00

  • Screening behavior of women after a false-positive mammogram.

    abstract:PURPOSE:To determine the effect of a false-positive mammogram that leads to open surgical biopsy on subsequent screening mammography behavior in women. MATERIALS AND METHODS:This study was performed with a retrospective cohort design, and data were collected by means of telephone interview. All participants were women...


    pub_type: 杂志文章


    authors: Pisano ED,Earp J,Schell M,Vokaty K,Denham A

    更新日期:1998-07-01 00:00:00

  • White matter anisotropy in childhood medulloblastoma survivors: association with neurotoxicity risk factors.

    abstract:PURPOSE:To prospectively evaluate the relationships between change in white matter (WM) anisotropy and (a) patient age at craniospinal irradiation (CSI), (b) CSI dose, and (c) time of magnetic resonance (MR) imaging since CSI and to determine the effect of these neurotoxicity risk factors on WM anisotropy in posttreatm...


    pub_type: 杂志文章


    authors: Khong PL,Leung LH,Chan GC,Kwong DL,Wong WH,Cao G,Ooi GC

    更新日期:2005-08-01 00:00:00

  • Postoperative radiation therapy in clinical stage I endometrial cancer: corpus, cervical, and lower uterine segment involvement--patterns of failure.

    abstract:PURPOSE:To evaluate involvement of the lower uterine segment (LUS) in adenocarcinoma of the endometrium and to identify patterns of treatment failure. MATERIALS AND METHODS:Two hundred four patients, aged 29-92 years, with endometrial carcinoma underwent surgery. Postoperative radiation therapy was administered for ad...


    pub_type: 杂志文章


    authors: Mayr NA,Wen BC,Benda JA,Sorosky JI,Davis CS,Fuller RW,Hussey DH

    更新日期:1995-08-01 00:00:00

  • CT perfusion scanning with deconvolution analysis: pilot study in patients with acute middle cerebral artery stroke.

    abstract:PURPOSE:To measure mean cerebral blood flow (CBF) in ischemic and nonischemic territories and in low-attenuation regions in patients with acute stroke by using deconvolution-derived hemodynamic imaging. MATERIALS AND METHODS:Twelve patients with acute middle cerebral artery stroke and 12 control patients were examined...


    pub_type: 杂志文章


    authors: Eastwood JD,Lev MH,Azhari T,Lee TY,Barboriak DP,Delong DM,Fitzek C,Herzau M,Wintermark M,Meuli R,Brazier D,Provenzale JM

    更新日期:2002-01-01 00:00:00