Abstract:
PURPOSE:To evaluate the effect of the increase in total cross-sectional area of arteries as they branch beyond the main trunks on the resistive index (RI) and early systolic acceleration (ESA). MATERIALS AND METHODS:An essentially noncompliant in vitro model that used a pulsatile pump, blood-mimicking fluid, and a branching tubing network that could be configured to produce a downstream cross-sectional area one, two, four, or eight times that of the feeding vessel was used to investigate the relationship, if any, between arterial bed cross-sectional area and the RI and ESA. RESULTS:The mean ESA in the branching network was inversely proportional to cross-sectional area, decreasing by approximately a factor of two for every doubling of the cross-sectional area. The mean RI in the branching network decreased with increasing cross-sectional area, but not as greatly as the ESA did; the mean RI in the bed with eight times the upstream cross-sectional area had an RI that was approximately three-fourths the upstream RI. These relationships are real, as the slopes of the plots (ESA vs cross-sectional area, P = .001; RI vs cross-sectional area, P < .02) are significantly different from zero. CONCLUSION:RI and ESA decrease as a result of increasing downstream cross-sectional diameter of the arterial bed.
journal_name
Radiologyjournal_title
Radiologyauthors
Bude RO,Rubin JMdoi
10.1148/radiology.212.3.r99se13732subject
Has Abstractpub_date
1999-09-01 00:00:00pages
732-8issue
3eissn
0033-8419issn
1527-1315journal_volume
212pub_type
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