当前位置： SCI文献检索 > ANESTHESIOLOGY期刊下所有文献 > Supervised Machine-learning Predictive Analytics for Prediction of Postinduction Hypotension.

Supervised Machine-learning Predictive Analytics for Prediction of Postinduction Hypotension.

Abstract：

WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Hypotension is a risk factor for adverse perioperative outcomes. Machine-learning methods allow large amounts of data for development of robust predictive analytics. The authors hypothesized that machine-learning methods can provide prediction for the risk of postinduction hypotension. METHODS:Data was extracted from the electronic health record of a single quaternary care center from November 2015 to May 2016 for patients over age 12 that underwent general anesthesia, without procedure exclusions. Multiple supervised machine-learning classification techniques were attempted, with postinduction hypotension (mean arterial pressure less than 55 mmHg within 10 min of induction by any measurement) as primary outcome, and preoperative medications, medical comorbidities, induction medications, and intraoperative vital signs as features. Discrimination was assessed using cross-validated area under the receiver operating characteristic curve. The best performing model was tuned and final performance assessed using split-set validation. RESULTS:Out of 13,323 cases, 1,185 (8.9%) experienced postinduction hypotension. Area under the receiver operating characteristic curve using logistic regression was 0.71 (95% CI, 0.70 to 0.72), support vector machines was 0.63 (95% CI, 0.58 to 0.60), naive Bayes was 0.69 (95% CI, 0.67 to 0.69), k-nearest neighbor was 0.64 (95% CI, 0.63 to 0.65), linear discriminant analysis was 0.72 (95% CI, 0.71 to 0.73), random forest was 0.74 (95% CI, 0.73 to 0.75), neural nets 0.71 (95% CI, 0.69 to 0.71), and gradient boosting machine 0.76 (95% CI, 0.75 to 0.77). Test set area for the gradient boosting machine was 0.74 (95% CI, 0.72 to 0.77). CONCLUSIONS:The success of this technique in predicting postinduction hypotension demonstrates feasibility of machine-learning models for predictive analytics in the field of anesthesiology, with performance dependent on model selection and appropriate tuning.

journal_name

Anesthesiology

journal_title

Anesthesiology

authors

Kendale S,Kulkarni P,Rosenberg AD,Wang J

doi

10.1097/ALN.0000000000002374

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

675-688

issue

eissn

0003-3022

issn

1528-1175

journal_volume

129

pub_type

杂志文章

在线工具

Supervised Machine-learning Predictive Analytics for Prediction of Postinduction Hypotension.