New ultrathin-walled endotracheal tube with a novel laryngeal seal design. Long-term evaluation in sheep.

abstract：BACKGROUND:Hyperkalemic cardiac arrest after the administration of succinylcholine (SCh) to critically ill intensive care patients has been attributed to changes in the acetylcholine receptors (AChRs) at the muscle membrane. The current study attempts to characterize the contributory roles of chronic administration of ...

journal_title：Anesthesiology

authors： Yanez P,Martyn JA

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:The abundance of a specific sodium channel subunit (SkM2) appeared to be altered in vitro in cell cultures from persons susceptible to malignant hyperthermia. This study sought to determine whether these findings are artifacts of cell culture or whether they may be relevant to malignant hyperthermia. METHOD...

journal_title：Anesthesiology

authors： Fletcher JE,Wieland SJ,Karan SM,Beech J,Rosenberg H

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Previous experimental and clinical studies have shown that anesthetic agents have varying effects on cancer prognosis; however, the results were inconsistent among these studies. The authors compared overall and recurrence-free survival in patients given volatile or intravenous anesthesia for digestive tract...

journal_title：Anesthesiology

authors： Makito K,Matsui H,Fushimi K,Yasunaga H

更新日期：2020-10-01 00:00:00

abstract：:Making good decisions in the era of Big Data requires a sophisticated approach to causality. We are acutely aware that association ≠ causation, yet untangling the two remains one of our greatest challenges. This realization has stimulated a Causal Revolution in epidemiology, and the lessons learned are highly relevant...

journal_title：Anesthesiology

authors： Gaskell AL,Sleigh JW

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Cortical acetylcholine originates in the basal forebrain and is essential for maintaining normal cognition and arousal. Morphine impairs these cholinergically mediated cortical functions. The current study tested the hypothesis that morphine decreases prefrontal cortical acetylcholine release by acting at th...

journal_title：Anesthesiology

authors： Osman NI,Baghdoyan HA,Lydic R

更新日期：2005-10-01 00:00:00

abstract：:The anesthetic requirements for sevoflurane, isoflurane, and halothane were determined in mongrel dogs. The MACs (minimum alveolar concentration) of sevoflurane, isoflurane, and halothane were 2.36 +/- 0.46% (n = 18), 1.39 +/- 0.25% (n = 10), and 0.89 +/- 0.20% (n = 12), respectively (mean +/- SD). In agreement with s...

journal_title：Anesthesiology

authors： Kazama T,Ikeda K

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Whether the fetus can experience pain remains controversial. During the last half of pregnancy, the neuroanatomic connections for nociception are in place, and the human fetus mounts sizable stress responses to physical insults. Analgesia has been recommended for intrauterine procedures or late termination, ...

journal_title：Anesthesiology

authors： Fisk NM,Gitau R,Teixeira JM,Giannakoulopoulos X,Cameron AD,Glover VA

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the relationship of four postanesthesia care unit (PACU) cardiovascular events to long-term outcomes (unplanned critical care admission or mortality) and to evaluate the contribution of anesthetic management compared with other perioperative factors in predicting th...

journal_title：Anesthesiology

authors： Rose DK,Cohen MM,DeBoer DP

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Age is a known risk factor for postoperative complications, but the genetic factors that account for variability in age at presentation for surgery have not been characterized. Because thrombosis is a critical process in the development of coronary syndromes, the authors hypothesized that patients bearing th...

journal_title：Anesthesiology

authors： Donahue BS,Byrne DW,Gailani D,George AL Jr

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:During experimental cardiac arrest, continuous insufflation of air or oxygen (CIO) through microcannulas inserted into the inner wall of a modified intubation tube and generating a permanent positive intrathoracic pressure, combined with external cardiac massage, has previously been shown to be as effective ...

journal_title：Anesthesiology

authors： Saïssy JM,Boussignac G,Cheptel E,Rouvin B,Fontaine D,Bargues L,Levecque JP,Michel A,Brochard L

更新日期：2000-06-01 00:00:00

abstract：:The need for accurate clinical diagnosis and appropriate intervention requires that a modern blood-gas laboratory have the means to correct for significant discrepancies between patient temperature and the temperature at which in vitro blood samples are analyzed. Recent advances in mini- and microcomputer technology p...

journal_title：Anesthesiology

authors： Andritsch RF,Muravchick S,Gold MI

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Inhaled nitric oxide (NO) may be useful in the treatment of adult respiratory distress syndrome and other diseases characterized by pulmonary hypertension and hypoxemia. NO is rapidly converted to nitrogen dioxide (NO2) in oxygen (O2) environments. We hypothesized that in patients whose lungs are mechanicall...

journal_title：Anesthesiology

authors： Nishimura M,Hess D,Kacmarek RM,Ritz R,Hurford WE

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Anesthetics inhibit airway smooth muscle contraction in part by a direct effect on the smooth muscle cell. This study tested the hypothesis that the anesthetics halothane and hexanol, which both relax airway smooth muscle in vitro, inhibit acetylcholine-promoted nucleotide exchange at the alpha subunit of th...

journal_title：Anesthesiology

authors： Sakihara C,Perkins WJ,Warner DO,Jones KA

更新日期：2004-07-01 00:00:00

abstract：:The authors had previously observed a deleterious cerebrovascular effect of prolonged hypothermia in primates and cats. In this study they examined the systemic as well as cerebral hemodynamic and metabolic effects of 24 hours of hypothermia in the dog. With decreases in temperature to 29 C, cardiac output (Q) and who...

journal_title：Anesthesiology

authors： Steen PA,Milde JH,Michenfelder JD

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Mechanical ventilation is delivered to sedated patients during anesthesia, but also to nonsedated patients (ventilator weaning, noninvasive ventilation). In these circumstances, patient-ventilator asynchrony may occur, provoking discomfort and unduly increasing work of breathing. In certain cases, it is asso...

journal_title：Anesthesiology

authors： Raux M,Ray P,Prella M,Duguet A,Demoule A,Similowski T

更新日期：2007-11-01 00:00:00

abstract：:Hepatic drug-metabolizing enzymes and hepatic ultrastructure were studied in rats after two hours of anesthesia with 1 MAC halothane or diethyl ether. Twelve hours after cessation of either anesthetic smooth endoplasmic reticulum was increased in centrilobular but not in periportal hepatocytes. This change persisted a...

journal_title：Anesthesiology

authors： Ross WT Jr,Cardell RR Jr

更新日期：1978-05-01 00:00:00

abstract：:Neurophysiologic and local cerebral metabolic mapping techniques indicate that seizures associated with lidocaine toxicity originate in subcortical brain structures. Normally local cerebral blood flow (l-CBF) is quantitatively coupled to local cerebral metabolic rate for glucose (l-CMRg). In the present study the resp...

journal_title：Anesthesiology

authors： Tommasino C,Maekawa T,Shapiro HM

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Hemodilution (HD) with oxyhemoglobin colloid (oxyHb) provides a greater arterial oxygen content (CaO2) than HD with conventional colloids; however, oxygen delivery (DO2) is essentially the same, because, in contrast to conventional HD, cardiac output (CO) is not augmented. This study seeks to elucidate the m...

journal_title：Anesthesiology

authors： Rooney MW,Hirsch LJ,Mathru M

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Victims of organophosphate intoxication with cholinergic crisis may have need for sedation and anesthesia, but little is known about how anesthetics work in these patients. Recent studies suggest that cholinergic stimulation impairs gamma-aminobutyric acid type A (GABAA) receptor function. Because GABAA rece...

journal_title：Anesthesiology

authors： Grasshoff C,Drexler B,Hentschke H,Thiermann H,Antkowiak B

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Mask ventilation is considered a "basic" skill for airway management. A one-handed "EC-clamp" technique is most often used after induction of anesthesia with a two-handed jaw-thrust technique reserved for difficult cases. Our aim was to directly compare both techniques with the primary outcome of air exchang...

journal_title：Anesthesiology

authors： Joffe AM,Hetzel S,Liew EC

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Positive end expiratory pressure (PEEP) is an important component of therapy in patients with acute lung injury or acute respiratory distress syndrome. The independent effect of PEEP on mortality is currently unknown. METHODS:A systematic review and meta-analysis of randomized controlled clinical trials com...

journal_title：Anesthesiology

authors： Phoenix SI,Paravastu S,Columb M,Vincent JL,Nirmalan M

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Age is often the sole criterion for determining the need for preoperative electrocardiograms. However, screening electrocardiograms have not been shown to add value above clinical information. This study was designed to determine whether it is possible to target electrocardiograms ordering to patients most l...

journal_title：Anesthesiology

authors： Correll DJ,Hepner DL,Chang C,Tsen L,Hevelone ND,Bader AM

更新日期：2009-06-01 00:00:00

abstract：:To study the effect of needle bevel direction on the incidence and severity of headache following inadvertent dural puncture occurring during the identification of the epidural space, the authors randomly assigned obstetric anesthesia residents to identify epidural space with the bevel of the epidural needle oriented ...

journal_title：Anesthesiology

authors： Norris MC,Leighton BL,DeSimone CA

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Management of cardiovascular implantable electronic devices (CIEDs), including pacemakers and implantable cardioverter defibrillators, for surgical procedures is challenging due to the increasing number of patients with CIEDs and limited availability of trained providers. At the authors' institution, a small...

journal_title：Anesthesiology

authors： Rooke GA,Lombaard SA,Van Norman GA,Dziersk J,Natrajan KM,Larson LW,Poole JE

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:During laparoscopic surgery utilizing carbon dioxide as the insufflating agent, nitrous oxide will diffuse into the peritoneal cavity if it is used as part of the anesthetic. Bowel perforation and the subsequent release of volatile bowel gas could create a explosion hazard. METHODS:Two related studies were ...

journal_title：Anesthesiology

authors： Neuman GG,Sidebotham G,Negoianu E,Bernstein J,Kopman AF,Hicks RG,West ST,Haring L

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:mu-Opioids administered spinally produce a potent, dose-dependent analgesic response in preclinical and clinical investigations. Side-effect profile of these compounds may be altered as a function of pharmacokinetics. The effects of intrathecal and intraperitoneal remifentanil, an esterase-metabolized mu opi...

journal_title：Anesthesiology

authors： Buerkle H,Yaksh TL

更新日期：1996-01-01 00:00:00

abstract：:The effect of chronic renal failure (RF) on the pharmacokinetics of morphine was studied in nine patients with end-stage RF, aged 58 +/- 8 yr (SD), and in seven control patients, aged 58 +/- 15 yr, undergoing peripheral surgery under general anesthesia. All patients received 0.2 mg X kg-1 as an intravenous bolus injec...

journal_title：Anesthesiology

authors： Chauvin M,Sandouk P,Scherrmann JM,Farinotti R,Strumza P,Duvaldestin P

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Postoperative cognitive dysfunction is common, but it remains unclear whether there are long-term adverse cognitive effects of surgery combined with anesthesia. The authors examined the association between exposure to surgery and level of cognitive functioning in a sample of 8,503 middle-aged and elderly twi...

journal_title：Anesthesiology

authors： Dokkedal U,Hansen TG,Rasmussen LS,Mengel-From J,Christensen K

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Isoflurane administration is known to increase extracellular dopamine (DA) concentration. Because the dopamine transporter (DAT) is a key regulator of DA, it is likely affected by isoflurane. This study investigates the hypothesis that isoflurane inhibits DA reuptake by causing DAT to be trafficked into the ...

journal_title：Anesthesiology

authors： Votaw J,Byas-Smith M,Hua J,Voll R,Martarello L,Levey AI,Bowman FD,Goodman M

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Although one-lung ventilation (OLV) has become an established procedure during thoracic surgery, sparse data exist about inflammatory alterations in the deflated, reventilated lung. The aim of this study was to prospectively investigate the effect of OLV on the pulmonary inflammatory response and to assess p...

journal_title：Anesthesiology

authors： De Conno E,Steurer MP,Wittlinger M,Zalunardo MP,Weder W,Schneiter D,Schimmer RC,Klaghofer R,Neff TA,Schmid ER,Spahn DR,Z'graggen BR,Urner M,Beck-Schimmer B

更新日期：2009-06-01 00:00:00