Effect of direct fetal opioid analgesia on fetal hormonal and hemodynamic stress response to intrauterine needling.

abstract：BACKGROUND:Furosemide and mannitol are used to reduce intracranial pressure, but the impact of furosemide on edema of injured brain is unclear. The authors examined the effects of furosemide and mannitol, alone and in combination, on brain water content in brain-injured rats. METHODS:Anesthetized rats were subjected t...

journal_title：Anesthesiology

authors： Todd MM,Cutkomp J,Brian JE

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Perioperative beta-blockade has been shown to improve long-term cardiac outcome in noncardiac surgical patients. A possible mechanism for the reduced risk of perioperative myocardial infarction is the attenuation of the excitotoxic effects of catecholamine surges by beta-blockade. It was hypothesized that be...

journal_title：Anesthesiology

authors： Zaugg M,Tagliente T,Lucchinetti E,Jacobs E,Krol M,Bodian C,Reich DL,Silverstein JH

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Potential deleterious effect of multiple anesthesia exposures on the developing brain remains a clinical concern. We hypothesized that multiple neonatal anesthesia exposures are more detrimental to brain maturation than an equivalent single exposure, with more pronounced long-term behavioral consequences. We...

journal_title：Anesthesiology

authors： Makaryus R,Lee H,Robinson J,Enikolopov G,Benveniste H

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Ulnar neuropathy is well-recognized as a potential complication of procedures performed on anesthetized patients. However, reported outcomes and risk factors for this problem are based on small series and anecdotes. METHODS:We retrospectively reviewed the perioperative courses of 1,129,692 consecutive patie...

journal_title：Anesthesiology

authors： Warner MA,Warner ME,Martin JT

更新日期：1994-12-01 00:00:00

abstract：:Previous investigators have identified an aortic-to-radial artery pressure gradient thought to develop during rewarming and discontinuation of cardiopulmonary bypass. The authors measured mean aortic and radial artery pressures before, during, and after cardiopulmonary bypass in 30 patients, to determine when the pres...

journal_title：Anesthesiology

authors： Rich GF,Lubanski RE Jr,McLoughlin TM

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The sevoflurane degradation product compound A is nephrotoxic in rats. In contrast, patient exposure to compound A during sevoflurane anesthesia has no clinically significant renal effects. The mechanism for this difference is incompletely understood. One possibility is that the metabolism and toxicity of co...

journal_title：Anesthesiology

authors： Kharasch ED,Schroeder JL,Sheffels P,Liggitt HD

更新日期：2005-12-01 00:00:00

abstract：:The pattern of breathing and lung mechanics were evaluated during the first 7 h of life in full-term healthy newborns delivered by cesarean section with bupivacaine epidural anesthesia, without (group 1) or with the addition of 100 micrograms of fentanyl (group 2). Respiration and oxyhemoglobin saturation (SpO2) were ...

journal_title：Anesthesiology

authors： Benlabed M,Dreizzen E,Ecoffey C,Escourrou P,Migdal M,Gaultier C

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Ethical conduct in human research in anesthesia includes approval by an institutional review board (IRB) or ethics committee and informed consent. Evidence of these is sometimes lacking in journal publications. METHODS:The authors reviewed all publications involving human subjects in six leading anesthesia ...

journal_title：Anesthesiology

authors： Myles PS,Tan N

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Inhalation anesthetics may interfere with the synthesis or action of endothelium-derived vasoactive factors. We investigated the effects of desflurane, enflurane, halothane, isoflurane, and sevoflurane on the release of nitric oxide and endothelium-derived hyperpolarizing factor (EDHF) in the isolated endoth...

journal_title：Anesthesiology

authors： Lischke V,Busse R,Hecker M

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine is an alpha 2 agonist with potential utility in clinical anesthesia for both its sedative and sympatholytic properties. METHODS:The pharmacokinetics and hemodynamic changes that occurred in ten healthy male volunteers were determined after administration of dexmedetomidine 2 micrograms/kg by...

journal_title：Anesthesiology

authors： Dyck JB,Maze M,Haack C,Vuorilehto L,Shafer SL

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Hyperkalemic cardiac arrest after the administration of succinylcholine (SCh) to critically ill intensive care patients has been attributed to changes in the acetylcholine receptors (AChRs) at the muscle membrane. The current study attempts to characterize the contributory roles of chronic administration of ...

journal_title：Anesthesiology

authors： Yanez P,Martyn JA

更新日期：1996-02-01 00:00:00

abstract：:Minute ventilation (VE), tidal volume (VT), carbon dioxide elimination (VCO2), and end-tidal (PETCO2) and arterial CO2 tensions (PaCO2) were measured in 39 anesthetized infants and children with body weights ranging from 3.1 to 31 kg. Eighteen children had normal cardiopulmonary function, seven had acyanotic congenita...

journal_title：Anesthesiology

authors： Lindahl SG,Yates AP,Hatch DJ

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:General anesthetics may modify airway responsiveness. The authors investigated the effect of thiopental, propofol, and etomidate on airway smooth muscle. METHODS:Contraction experiments were done in human airway rings that were either normal or passively sensitized with asthmatic serum. The effect of propof...

journal_title：Anesthesiology

authors： Ouedraogo N,Roux E,Forestier F,Rossetti M,Savineau JP,Marthan R

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Ketamine has been associated with a unique spectrum of subjective "psychedelic" effects in patients emerging from anesthesia. This study quantified these effects of ketamine and related them to steady-state plasma concentrations. METHODS:Ketamine or saline was administered in a single-blinded crossover prot...

journal_title：Anesthesiology

authors： Bowdle TA,Radant AD,Cowley DS,Kharasch ED,Strassman RJ,Roy-Byrne PP

更新日期：1998-01-01 00:00:00

abstract：:To evaluate the effect of Bicitra (Willen Drug Company, Baltimore, Maryland), a commercial preparation of sodium citrate and metoclopramide, on gastric contents 150 elective outpatients allocated into six groups with 25 patients in each group were studied. Patients in Group 1 served as controls. Patients in Groups 2, ...

journal_title：Anesthesiology

authors： Manchikanti L,Grow JB,Colliver JA,Hadley CH,Hohlbein LJ

更新日期：1985-10-01 00:00:00

abstract：:The authors used pharmacokinetic and pharmacodynamic modeling to explain the time course of neuromuscular blockade following single or multiple doses of three nondepolarizing muscle relaxants. Published and unpublished pharmacokinetic and pharmacodynamic data for 13 normal subjects were used to simulate the duration o...

journal_title：Anesthesiology

authors： Fisher DM,Rosen JI

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:We compared the effects of etomidate and ketamine on the hypothalamic-pituitary-adrenal axis during sepsis. METHODS:Mice (n = 5/group) were injected intraperitoneally with lipopolysaccharide (10 mg/kg) and 6 h later randomized to receive ketamine (100 mg/kg), etomidate (30 mg/kg), or saline. At two time poi...

journal_title：Anesthesiology

authors： Besnier E,Clavier T,Tonon MC,Selim J,Lefevre-Scelles A,Morin F,Tamion F,Dureuil B,Castel H,Compere V

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Neurocognitive dysfunction is a common complication of cardiac surgery using cardiopulmonary bypass (CPB). Elucidating injury mechanisms and developing neuroprotective strategies have been hampered by the lack of a suitable long-term recovery model of CPB. The purpose of this study was to investigate neurolo...

journal_title：Anesthesiology

authors： Mackensen GB,Sato Y,Nellgård B,Pineda J,Newman MF,Warner DS,Grocott HP

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to characterize cervical cord, root, and bony spine claims in the American Society of Anesthesiologists Closed Claims database to formulate hypotheses regarding mechanisms of injury. METHODS:All general anesthesia claims (1970-2007) in the Closed Claims database were searched to id...

journal_title：Anesthesiology

authors： Hindman BJ,Palecek JP,Posner KL,Traynelis VC,Lee LA,Sawin PD,Tredway TL,Todd MM,Domino KB

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Phantom and stump pains, common sequelae of limb amputations, are significant impediments to rehabilitation of amputees. The pathophysiology and optimal treatment of postamputation pain states are unclear. While stump pain may result from neuromas in the stump, phantom pain is thought to be related to cortic...

journal_title：Anesthesiology

authors： Wu CL,Tella P,Staats PS,Vaslav R,Kazim DA,Wesselmann U,Raja SN

更新日期：2002-04-01 00:00:00

abstract：:The effects of halothane on the beating response of rat heart cells in tissue culture were studied using an optical-electronic monitoring device. A dose-response curve was obtained over a concentration range to as much as 5 vol per cent halothane. The clinical dosage of 1 vol per cent halothane decreased the inotropic...

journal_title：Anesthesiology

authors： Stong LJ,Hartzell CR,McCarl RL

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Inhaled nitric oxide (NO), an endothelium-derived relaxing factor, is a selective pulmonary vasodilator. The authors investigated whether inhaled NO decreases pulmonary vascular resistance (PVR) while preserving hypoxic pulmonary vasoconstriction and whether it maintains or improves oxygenation in patients d...

journal_title：Anesthesiology

authors： Rich GF,Lowson SM,Johns RA,Daugherty MO,Uncles DR

更新日期：1994-01-01 00:00:00

abstract：:This study examined the efficacy of patient-controlled epidural analgesia (PCEA) during labor and compared the suitability of three different PCEA solutions. After establishing effective epidural analgesia with 12 ml of 0.25% bupivacaine, 72 parturients in active labor were randomly assigned to one of four groups: phy...

journal_title：Anesthesiology

authors： Lysak SZ,Eisenach JC,Dobson CE 2nd

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Studies have shown that long-term increase in the excitability of single wide dynamic range neurones in the spinal dorsal horn of rats may be induced after tetanic stimulation to the sciatic nerve. This sensory event is possibly an in vivo counterpart of long-term potentiation, described in the brain. This s...

journal_title：Anesthesiology

authors： Rygh LJ,Green M,Athauda N,Tjølsen A,Dickenson AH

更新日期：2000-01-01 00:00:00

abstract：:The authors sought to determine if isoflurane would attenuate effects of three different types of vasoconstrictors on isolated segments of canine epicardial coronary arteries removed from healthy dogs. As the endothelium has a major role in regulating epicardial coronary artery tone, and as it modulates the effect of ...

journal_title：Anesthesiology

authors： Blaise G,Sill JC,Nugent M,Van Dyke RA,Vanhoutte PM

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:Patients with initial mild acute respiratory distress syndrome are often underrecognized and mistakenly considered to have low disease severity and favorable outcomes. They represent a relatively poorly characterized population that was only classified as having acute respiratory distress syndrome in the mos...

journal_title：Anesthesiology

authors： Pham T,Serpa Neto A,Pelosi P,Laffey JG,De Haro C,Lorente JA,Bellani G,Fan E,Brochard LJ,Pesenti A,Schultz MJ,Artigas A,LUNG SAFE Investigators* and the European Society of Intensive Care Medicine Trials Group.

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics depress left ventricular contractile function by altering voltage-dependent slow calcium (Ca2+) channel activity in the sarcolemmal membrane. This investigation examined the left ventricular systolic and diastolic mechanical effects of the dihydropyridine Ca2+ channel antagonist nifedipi...

journal_title：Anesthesiology

authors： Pagel PS,Hettrick DA,Warltier DC

更新日期：1994-07-01 00:00:00

abstract：:Cognitive performance in postsurgical patients may be impaired by disturbances of normal circadian rhythm analogous to those produced by rapid transmeridian travel ("jet lag"). We therefore tested the hypothesis that isoflurane anesthesia alone produces a phase-delay in the human circadian temperature rhythm. We monit...

journal_title：Anesthesiology

authors： Sessler DI,Lee KA,McGuire J

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:The mechanisms of action of general anesthetics are not completely understood. Many general anesthetics are reported to potentiate gamma-aminobutyric acid (GABAA) and glycine receptors in the central nervous system (CNS) and to inhibit the muscle-type nicotinic acetylcholine receptor (nAChR). The effects of ...

journal_title：Anesthesiology

authors： Flood P,Ramirez-Latorre J,Role L

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:The observation that peripheral trauma causes enhanced spinal neuronal excitability has provided the scientific rationale for the concept of "pre-emptive analgesia." The premise has been that only noxious stimuli cause sensitization in sensory pathways, but this premise has not been tested in the conscious s...

journal_title：Anesthesiology

authors： Herrero JF,Headley PM

更新日期：1995-01-01 00:00:00