Morphine inhibits acetylcholine release in rat prefrontal cortex when delivered systemically or by microdialysis to basal forebrain.

abstract：BACKGROUND:Long-term neuroprotection by isoflurane has been questioned. The authors examined factors in experimental models potentially critical to definition of enduring isoflurane neuroprotection. METHODS:Rats were prepared for temporary middle cerebral artery occlusion (MCAO). Pericranial normothermia was maintaine...

journal_title：Anesthesiology

authors： Sakai H,Sheng H,Yates RB,Ishida K,Pearlstein RD,Warner DS

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Anesthesia during the synaptogenic period induces dendritic spine formation, which may affect neurodevelopment. The authors, therefore, evaluated whether changes in synaptic transmission after dendritic spine formation induced by sevoflurane were associated with long-term behavioral changes. The effects of s...

journal_title：Anesthesiology

authors： Chung W,Ryu MJ,Heo JY,Lee S,Yoon S,Park H,Park S,Kim Y,Kim YH,Yoon SH,Shin YS,Lee WH,Ju X,Kweon GR,Ko Y

更新日期：2017-02-01 00:00:00

abstract：:We recorded the frequency with which anesthesia personnel came in contact with patient body fluids in order to provide an empirical basis for the recommendation of relevant precautions. Anesthesia personnel completed a questionnaire when performing a range of standardized procedures. The rate of contact with blood was...

journal_title：Anesthesiology

authors： Kristensen MS,Sloth E,Jensen TK

更新日期：1990-10-01 00:00:00

abstract：:The effects of subparalytic doses of succinylcholine and d-tubocurarine on epinephrine-induced cardiac arrhythmias during halothane anesthesia were evaluated in dogs. Succinylcholine markedly increased (P is less than .05) the arrhythmogenicity of epinephrine and d-tubocurarine slightly decreased (P is less than .05) ...

journal_title：Anesthesiology

authors： Tucker WK,Munson ES

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:Patients with brain injury are at high risk of extubation failure. METHODS:We conducted a prospective observational cohort study in four intensive care units of three university hospitals. The aim of the study was to create a score that could predict extubation success in patients with brain injury. RESULT...

journal_title：Anesthesiology

authors： Asehnoune K,Seguin P,Lasocki S,Roquilly A,Delater A,Gros A,Denou F,Mahé PJ,Nesseler N,Demeure-Dit-Latte D,Launey Y,Lakhal K,Rozec B,Mallédant Y,Sébille V,Jaber S,Le Thuaut A,Feuillet F,Cinotti R,ATLANREA group.

更新日期：2017-08-01 00:00:00

abstract：:This study was designed to assess the relationship between MAC and hypertension. To this purpose, MAC of halothane was determined in fully inbred spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY). Because MAC determination was performed in animals whose lungs were mechanically ventilated, the adequacy ...

journal_title：Anesthesiology

authors： Wouters P,Doursout MF,Merin RG,Chelly JE

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Many studies have demonstrated that either glutamate -methyl-d-aspartate (NMDA) receptor antagonists or opioid receptor agonists provide antinociception. Spinal coadministration of an NMDA receptor antagonist and morphine has an additive action for control of various pain states in animal models. The current...

journal_title：Anesthesiology

authors： Lu Y,Vera-Portocarrero LP,Westlund KN

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Macrophage recruitment into atherosclerotic plaques drives lesion progression, destabilization, and rupture. Chronic statin treatment reduces macrophage plaque content. Information on dynamics of macrophage recruitment would help assessing plaque vulnerability and guiding therapy. Techniques to image macroph...

journal_title：Anesthesiology

authors： Larmann J,Frenzel T,Schmitz M,Hahnenkamp A,Demmer P,Immenschuh S,Tietge UJ,Bremer C,Theilmeier G

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:About one in four patients suffers from postoperative nausea and vomiting. Fortunately, risk scores have been developed to better manage this outcome in hospitalized patients, but there is currently no risk score for postdischarge nausea and vomiting (PDNV) in ambulatory surgical patients. METHODS:We conduc...

journal_title：Anesthesiology

authors： Apfel CC,Philip BK,Cakmakkaya OS,Shilling A,Shi YY,Leslie JB,Allard M,Turan A,Windle P,Odom-Forren J,Hooper VD,Radke OC,Ruiz J,Kovac A

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The authors sought to understand neural correlates of anesthetic-induced unconsciousness. Cortical gamma oscillations have been associated with neural processes supporting conscious perception, but the effect of general anesthesia on these oscillations is controversial. In this study, the authors examined th...

journal_title：Anesthesiology

authors： Imas OA,Ropella KM,Ward BD,Wood JD,Hudetz AG

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Hypoperfusion of the intestinal mucosa remains an important clinical problem during sepsis. Impairment of the autoregulation of microcirculatory blood flow in the intestinal tract has been suggested to play an important role in the development of multiple organ failure during sepsis and surgery. The authors ...

journal_title：Anesthesiology

authors： Hiltebrand LB,Krejci V,tenHoevel ME,Banic A,Sigurdsson GH

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Insufficient data exist on the production of compound A during closed-system sevoflurane administration with newer carbon dioxide absorbents. METHODS:A modified PhysioFlex apparatus (Dräger, Lübeck, Germany) was connected to an artificial test lung (inflow at the top of the bellow approximately/= 160 ml/min...

journal_title：Anesthesiology

authors： Versichelen LF,Bouche MP,Rolly G,Van Bocxlaer JF,Struys MM,De Leenheer AP,Mortier EP

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Renal and hepatic toxicity of the fluorinated ether volatile anesthetics is caused by biotransformation to toxic metabolites. Metabolism also contributes significantly to the elimination pharmacokinetics of some volatile agents. Although innumerable studies have explored anesthetic metabolism in animals, the...

journal_title：Anesthesiology

authors： Kharasch ED,Thummel KE

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Airway pressure-release ventilation provides ventilation comparable to controlled mechanical ventilation (CMV), but with lower peak airway pressures and less dead-space ventilation. To obtain these advantages for patients administered general anesthesia, the authors (1) designed a mode similar to airway pres...

journal_title：Anesthesiology

authors： Bratzke E,Downs JB,Smith RA

更新日期：1998-08-01 00:00:00

abstract：:Fentanyl is used as an analgesic in small doses (1-2 micrograms X kg-1) and as an anesthetic in very large doses (greater than 150 micrograms X kg-1). It has been demonstrated that the effects of fentanyl correlate with its concentrations in plasma. It is important, therefore, to know whether or not the pharmacokineti...

journal_title：Anesthesiology

authors： Murphy MR,Hug CC Jr,McClain DA

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Age is a known risk factor for postoperative complications, but the genetic factors that account for variability in age at presentation for surgery have not been characterized. Because thrombosis is a critical process in the development of coronary syndromes, the authors hypothesized that patients bearing th...

journal_title：Anesthesiology

authors： Donahue BS,Byrne DW,Gailani D,George AL Jr

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Neural glial signaling in the spinal cord may underlie pain and sensitization after peripheral injury. The authors test the role of a glial activator, the chemokine (C-C motif) ligand 2 (CCL2), on mechanical hypersensitivity after plantar incision in a rat model of postoperative pain. METHODS:Twenty-four ho...

journal_title：Anesthesiology

authors： Peters CM,Eisenach JC

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The authors compared the intubation success rate of straight reinforced tracheal tubes emerging from the Airtraq laryngoscope (Prodol Meditec S.A., Vizcaya, Spain) with standard preformed polyvinyl chloride tracheal tubes in anesthetized patients. METHODS:The authors randomly allocated 347 adult patients to...

journal_title：Anesthesiology

authors： Dimitriou VK,Zogogiannis ID,Douma AK,Pentilas ND,Liotiri DG,Wachtel MS,Karakitsos D

更新日期：2009-12-01 00:00:00

abstract：:Changes in hepatic plasma flow (HPF) during sodium nitroprusside (SNP) induced hypotension were studied in 14 patients undergoing intracranial aneurysm surgery under neurolept anesthesia. Patients were monitored with the use of a radial artery catheter and a thermistor-tipped Swan-Ganz catheter. Hypotension was induce...

journal_title：Anesthesiology

authors： Chauvin M,Bonnet F,Montembault C,Lafay M,Curet P,Viars P

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) is a serious postoperative complication with limited treatment options. A preoperative risk-prediction model would assist clinicians and scientists interested in ALI. The objective of this investigation was to develop a surgical lung injury prediction (SLIP) model to predict risk of p...

journal_title：Anesthesiology

authors： Kor DJ,Warner DO,Alsara A,Fernández-Pérez ER,Malinchoc M,Kashyap R,Li G,Gajic O

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Acid aspiration into one lung causes contralateral lung injury and systemic organ injury; this injury is thought to be mediated by the sequestration of activated neutrophils. Recombinant human soluble complement receptor 1 (sCR1) inhibits both the classical and alternative complement pathways; this study inv...

journal_title：Anesthesiology

authors： Nishizawa H,Yamada H,Miyazaki H,Ohara M,Kaneko K,Yamakawa T,Wiener-Kronish J,Kudoh I

更新日期：1996-11-01 00:00:00

abstract：:The authors undertook a prospective study of 30 patients undergoing halothane anesthesia for coronary-artery revascularization to ascertain which clinically monitored hemodynamic variables--or combination of variables--associated with myocardial oxygen supply and demand best predict myocardial ischemia. Simultaneous r...

journal_title：Anesthesiology

authors： Lieberman RW,Orkin FK,Jobes DR,Schwartz AJ

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:The rate of administration of an intravenous anesthetic induction agent is an important variable determining the total dose required to reach a given endpoint, such as loss of consciousness (LOC). The influence of infusion rate on the dose-response relationship has not been described rigorously. In this stud...

journal_title：Anesthesiology

authors： Gentry WB,Krejcie TC,Henthorn TK,Shanks CA,Howard KA,Gupta DK,Avram MJ

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Medical errors exact an inordinate toll on healthcare costs. One of the most publicized and analyzed type of medical error is wrong-site surgery. Yet, despite the burgeoning number of procedures performed, no literature exists on wrong-site pain management injections. The purpose of this study was to estimat...

journal_title：Anesthesiology

authors： Cohen SP,Hayek SM,Datta S,Bajwa ZH,Larkin TM,Griffith S,Hobelmann G,Christo PJ,White R

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Cerebrospinal fluid (CSF) outflow to intra- and extracranial subarachnoid spaces caused by arterial inflow to the brain predominantly compensates systolic increases in cerebral blood volume. Phase-contrast magnetic resonance imaging is a new tool for noninvasive assessment of CSF displacement by measuring CS...

journal_title：Anesthesiology

authors： Kolbitsch C,Schocke M,Lorenz IH,Kremser C,Zschiegner F,Pfeiffer KP,Felber S,Aichner F,Hörmann C,Benzer A

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:A high proportion of patients having cardiac bypass surgery receive erythrocyte transfusions. Decisions about when to transfuse patients having surgery for coronary artery disease may impact on erythrocyte utilization and patient morbidity and mortality. There are no published data about the factors that inf...

journal_title：Anesthesiology

authors： Shehata N,Wilson K,Mazer CD,Tomlinson G,Streiner D,Hebert P,Naglie G

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:The analgesic efficacy and side effect profile of intravenous parecoxib, a novel cyclooxygenase type-2 (COX-2) inhibitor, was assessed in a double-blinded, placebo-controlled study involving patients undergoing major gynecologic surgical procedures. METHODS:After Institutional Review Board approval, 60 cons...

journal_title：Anesthesiology

authors： Tang J,Li S,White PF,Chen X,Wender RH,Quon R,Sloninsky A,Naruse R,Kariger R,Webb T,Norel E

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Prone ventilation redistributes lung inflation along the gravitational axis; however, localized, nongravitational effects of body position are less well characterized. The authors hypothesize that positional inflation improvements follow both gravitational and nongravitational distributions. This study is a ...

journal_title：Anesthesiology

authors： Xin Y,Cereda M,Hamedani H,Martin KT,Tustison NJ,Pourfathi M,Kadlecek S,Siddiqui S,Amzajerdian F,Connell M,Abate N,Kajanaku A,Duncan I,Gee JC,Rizi RR

更新日期：2020-11-01 00:00:00

abstract：:Four volunteers judged eight levels of thermal stimuli induced by a Hardy dolorimeter, varying in intensity from extremely painful to a low level seldom even perceived. Half of the 406 stimuli were applied during acupuncture and half either before insertion or after removal of the needles. The experimental design mini...

journal_title：Anesthesiology

authors： Day RL,Kitahata LM,Kao FF,Motoyama EK,Hardy JD

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:The combining of epidural anesthesia with general anesthesia impairs central and peripheral thermoregulatory control and therefore is often accompanied by unintended intraoperative hypothermia. However, little is known about the cardiovascular response to hypothermia during combined epidural and general anes...

journal_title：Anesthesiology

authors： Yoshida M,Shibata K,Itoh H,Yamamoto K

更新日期：2001-04-01 00:00:00