Cardiovascular responses to the induction of mild hypothermia in the presence of epidural anesthesia.

abstract：BACKGROUND:Vasospasm of arterial grafts represents an unpredictable complication of coronary artery surgery and may compromise myocardial revascularization, and treatment is based on empirical therapy with nitroglycerin. Because of the potential for tolerance to nitroglycerin to occur, the authors studied different vas...

journal_title：Anesthesiology

authors： Huraux C,Makita T,Montes F,Szlam F,Levy JH

更新日期：1998-06-01 00:00:00

abstract：:Critically ill patients often suffer from multiple organ failures involving lung, kidney, liver, or brain. Genomic, proteomic, and metabolomic approaches highlight common injury mechanisms leading to acute organ failure. This underlines the need to focus on therapeutic strategies affecting multiple injury pathways. Th...

journal_title：Anesthesiology

authors： Monsel A,Zhu YG,Gennai S,Hao Q,Liu J,Lee JW

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Recent studies have questioned the importance of the gravitational model of pulmonary perfusion. Because low levels of positive end-expiratory pressure (PEEP) are commonly used during anesthesia, the authors studied the distribution of pulmonary blood flow with low levels of PEEP using a high spatial resolut...

journal_title：Anesthesiology

authors： Kallas HJ,Domino KB,Glenny RW,Anderson EA,Hlastala MP

更新日期：1998-05-01 00:00:00

abstract：:The effect of pertussis toxin on opioid antinociception was studied in rats. Intrathecal injection of a single dose of pertussis toxin reduced the antinociceptive effect of PL017, a highly selective mu-opioid agonist, in a dose- and time-dependent manner. The maximal effective dose of pertussis toxin was 1 microgram, ...

journal_title：Anesthesiology

authors： Wong CS,Su YF,Chang KJ,Watkins WD

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:When performing experiments at room temperature with volatile general anesthetics and in vitro mammalian preparations (such as isolated neurons), the question arises as to which concentrations of anesthetics are "clinically relevant." Different choices can lead to different interpretations of the anesthetic ...

journal_title：Anesthesiology

authors： Franks NP,Lieb WR

更新日期：1996-03-01 00:00:00

abstract：:Intraventricular conduction disorders and reentrant arrhythmias in dogs can be produced by high plasma bupivacaine concentrations. The authors' aim was to determine if these conduction disturbances also occurred at moderate plasma bupivacaine concentrations (2.2-3.7 micrograms/ml) when in association with other factor...

journal_title：Anesthesiology

authors： Timour Q,Freysz M,Mazze R,Couzon P,Bertix L,Faucon G

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Although hyper- and hypoglycemia induce neurophysiologic changes, there have been no reports on the effects of blood glucose changes on anesthetic requirements. This study examined the effects of hyper- and hypoglycemia on the minimum alveolar concentration (MAC) of halothane in rats. In addition, based on a...

journal_title：Anesthesiology

authors： Ishizawa Y,Ohta S,Shimonaka H,Dohi S

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Pentobarbital decreases the gain of the baroreceptor reflex on the order of 50%, and this blunting is caused nearly entirely by decreasing cardioinhibitory parasympathetic activity. The most likely site of action of pentobarbital is the gamma-aminobutyric acid type A (GABA(A)) receptor. The authors tested wh...

journal_title：Anesthesiology

authors： Irnaten M,Walwyn WM,Wang J,Venkatesan P,Evans C,Chang KS,Andresen MC,Hales TG,Mendelowitz D

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP) monitoring with arterial waveform display requires an arterial cannula. We evaluated a new noninvasive device, Vasotrac (Medwave, Arden Hills, MN) that provides BP measurements approximately every 12-15 beats and displays pulse rate and a calibrated arterial waveform for each BP measureme...

journal_title：Anesthesiology

authors： Belani K,Ozaki M,Hynson J,Hartmann T,Reyford H,Martino JM,Poliac M,Miller R

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Inhaled nitric oxide (NO) may be useful in the treatment of adult respiratory distress syndrome and other diseases characterized by pulmonary hypertension and hypoxemia. NO is rapidly converted to nitrogen dioxide (NO2) in oxygen (O2) environments. We hypothesized that in patients whose lungs are mechanicall...

journal_title：Anesthesiology

authors： Nishimura M,Hess D,Kacmarek RM,Ritz R,Hurford WE

更新日期：1995-05-01 00:00:00

abstract：:Eighty-six patients undergoing coronary artery bypass graft (n = 63) or intracardiac (n = 23) surgery were randomly assigned with respect to the target value for PaCO2 during cardiopulmonary bypass. In 44 patients the target PaCO2 was 40 mmHg, measured at the standard electrode temperature of 37 degrees C, while in 42...

journal_title：Anesthesiology

authors： Bashein G,Townes BD,Nessly ML,Bledsoe SW,Hornbein TF,Davis KB,Goldstein DE,Coppel DB

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Halothane induces negative inotropic and lusitropic effects in myocardium. It has been suggested that halothane potentiates beta-adrenoceptor stimulation. However, its effects on the inotropic response to alpha-adrenoceptor stimulation and its effects on the lusitropic effects of alpha- and beta-adrenoceptor...

journal_title：Anesthesiology

authors： Hanouz JL,Riou B,Massias L,Lecarpentier Y,Coriat P

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The brain is assumed to be the site of anesthetic action, but anesthetics have effects elsewhere, such as the spinal cord. A preferentially anesthetized goat brain model was used to determine the importance of anesthetic action in the brain. METHODS:Six goats were anesthetized with isoflurane; after trachea...

journal_title：Anesthesiology

authors： Antognini JF,Schwartz K

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Drugs are routinely combined in anesthesia and pain management to obtain an enhancement of the desired effects. However, a parallel enhancement of the undesired effects might take place as well, resulting in a limited therapeutic usefulness. Therefore, when addressing the question of optimal drug combination...

journal_title：Anesthesiology

authors： Zanderigo E,Sartori V,Sveticic G,Bouillon T,Schumacher P,Morari M,Curatolo M

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to generate a score based on preoperative characteristics and predictive of the individual probability of allogeneic erythrocyte transfusion in patients undergoing elective thoracolumbar spine surgery. METHODS:Two hundred thirty consecutive patients were retrospectively included ov...

journal_title：Anesthesiology

authors： Lenoir B,Merckx P,Paugam-Burtz C,Dauzac C,Agostini MM,Guigui P,Mantz J

更新日期：2009-05-01 00:00:00

abstract：:Hepatic venous oxygen saturation (ShvO2) was continuously monitored in 33 consecutive patients undergoing hepatic lobectomy. Fiberoptic pulmonary artery catheters were inserted into the hepatic vein (HV) and in the pulmonary artery through the right internal jugular vein before anesthetic induction. The success rate a...

journal_title：Anesthesiology

authors： Kainuma M,Fujiwara Y,Kimura N,Shitaokoshi A,Nakashima K,Shimada Y

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Anesthesia personnel are at risk for occupational infection with bloodborne pathogens from contaminated percutaneous injuries (CPIs). Additional information is needed to formulate methods to reduce risk. METHODS:The authors analyzed CPIs collected during a 2-yr period at 11 hospitals, assessed CPI underrepo...

journal_title：Anesthesiology

authors： Greene ES,Berry AJ,Jagger J,Hanley E,Arnold WP 3rd,Bailey MK,Brown M,Gramling-Babb P,Passannante AN,Seltzer JL,Southorn P,Van Clief MA,Venezia RA

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine is an alpha 2 agonist with potential utility in clinical anesthesia for both its sedative and sympatholytic properties. METHODS:The pharmacokinetics and hemodynamic changes that occurred in ten healthy male volunteers were determined after administration of dexmedetomidine 2 micrograms/kg by...

journal_title：Anesthesiology

authors： Dyck JB,Maze M,Haack C,Vuorilehto L,Shafer SL

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Neurally adjusted ventilatory assist (NAVA) is a new mode of mechanical ventilation that delivers ventilatory assist in proportion to the electrical activity of the diaphragm. This study aimed to compare the ventilatory and gas exchange effects between NAVA and pressure support ventilation (PSV) during the w...

journal_title：Anesthesiology

authors： Coisel Y,Chanques G,Jung B,Constantin JM,Capdevila X,Matecki S,Grasso S,Jaber S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Thermoregulatory vasoconstriction minimizes further core hypothermia during anesthesia. Elderly patients become more hypothermic during surgery than do younger patients, and take longer to rewarm postoperatively. These data indicate that perianesthetic thermoregulatory responses may be especially impaired in...

journal_title：Anesthesiology

authors： Kurz A,Plattner O,Sessler DI,Huemer G,Redl G,Lackner F

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:In vitro studies have shown that isoflurane, enflurane, and halothane inhibit the hypoxic pulmonary vasoconstriction (HPV) with essentially the same potency. The aim of this study is to compare the effects of sevoflurane and isoflurane on HPV in constant-flow perfused rabbit lungs. METHODS:Constant-flow per...

journal_title：Anesthesiology

authors： Ishibe Y,Gui X,Uno H,Shiokawa Y,Umeda T,Suekane K

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The current study was performed to determine whether volatile anesthetics may include as part of their action in the central nervous system the depression of presynaptic transmitter release by alteration in intrasynaptic [Ca2+] ([Ca2+]i). METHODS:Guinea pig cerebrocortical synaptosomes were studied at 37 de...

journal_title：Anesthesiology

authors： Miao N,Frazer MJ,Lynch C 3rd

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Local anesthetics that produce analgesia of long duration with minimal impairment of autonomic functions are highly desirable for pain management in the clinic. Prenylamine is a known calcium channel blocker, but its local anesthetic blocking effects on voltage-gated sodium channels have not been studied thu...

journal_title：Anesthesiology

authors： Mujtaba MG,Gerner P,Wang GK

更新日期：2001-11-01 00:00:00

abstract：:Chloroprocaine, 0.5 per cent, with physiologic saline solution, has a specific gravity of 1.007 and a osmolarity of 283 mOsm/l, which increase to a specific gravity of 1.025 and an osmolarity of 542 mOsm/l when chloroprocaine is prepared in dextrose, 5 per cent. Chloroprocaine, 2.7 per cent, shows similar increases in...

journal_title：Anesthesiology

authors： Park YR,Eastwood DW

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Postoperative nausea and vomiting (PONV) occurs frequently after gynecologic surgery. Because hemodynamic condition seems to be influential, women presenting with preoperative orthostatic dysregulation may have an increased risk for PONV. The aim of the present study was to assess the relationship between pr...

journal_title：Anesthesiology

authors： Pusch F,Berger A,Wildling E,Zimpfer M,Moser M,Sam C,Krafft P

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Ketamine is a commonly used anesthetic, but the mechanistic basis for its clinically relevant actions remains to be determined. The authors previously showed that HCN1 channels are inhibited by ketamine and demonstrated that global HCN1 knockout mice are twofold less sensitive to hypnotic actions of ketamine...

journal_title：Anesthesiology

authors： Zhou C,Douglas JE,Kumar NN,Shu S,Bayliss DA,Chen X

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Acute respiratory distress syndrome (ARDS) is a devastating condition with an estimated mortality exceeding 30%. There are data suggesting risk factors for ARDS development in high-risk populations, but few data are available in lower incidence populations. Using risk-matched analysis and a combination of cl...

journal_title：Anesthesiology

authors： Blum JM,Stentz MJ,Dechert R,Jewell E,Engoren M,Rosenberg AL,Park PK

更新日期：2013-01-01 00:00:00

abstract：:Complications after major surgery are a leading cause of morbidity and mortality. The etiology of postoperative complications is complex, but poor cardiorespiratory reserve appears to be a key factor. There is increasing interest in the use of central and mixed venous oxygen saturation to guide therapeutic interventio...

journal_title：Anesthesiology

authors： Shepherd SJ,Pearse RM

更新日期：2009-09-01 00:00:00

abstract：AIMS:Helium protects myocardium by inducing preconditioning in animals. We investigated whether human endothelium is preconditioned by helium inhalation in vivo. METHODS AND RESULTS:Forearm ischemia-reperfusion (I/R) in healthy volunteers (each group n = 10) was performed by inflating a blood pressure cuff for 20 min....

journal_title：Anesthesiology

authors： Smit KF,Oei GT,Brevoord D,Stroes ES,Nieuwland R,Schlack WS,Hollmann MW,Weber NC,Preckel B

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The incidence of awareness has been reported to be higher in children than in adults. Accurately assessing awareness in children is difficult, and the lack of a specific measure of awareness makes it difficult to determine exactly how many and why children are aware. The aim of this study was to determine th...

journal_title：Anesthesiology

authors： Davidson AJ,Sheppard SJ,Engwerda AL,Wong A,Phelan L,Ironfield CM,Stargatt R

更新日期：2008-10-01 00:00:00