Effects of succinylcholine and d-tubocurarine on epinephrine-induced arrhythmias during halothane anesthesia in dogs.

Abstract:

:The effects of subparalytic doses of succinylcholine and d-tubocurarine on epinephrine-induced cardiac arrhythmias during halothane anesthesia were evaluated in dogs. Succinylcholine markedly increased (P is less than .05) the arrhythmogenicity of epinephrine and d-tubocurarine slightly decreased (P is less than .05) its arrhythmic effect. Prior administration of atropine resulted in a partial, but significant, reversal of this action of succinylcholine.

journal_name

Anesthesiology

journal_title

Anesthesiology

authors

Tucker WK,Munson ES

doi

10.1097/00000542-197501000-00008

subject

Has Abstract

pub_date

1975-01-01 00:00:00

pages

41-4

issue

1

eissn

0003-3022

issn

1528-1175

journal_volume

42

pub_type

杂志文章
  • Role of the O-linked β-N-acetylglucosamine in the cardioprotection induced by isoflurane.

    abstract:BACKGROUND:Cardiac protection by volatile anesthetic-induced preconditioning and ischemic preconditioning have similar signaling pathways. Recently, it was reported that augmentation of protein modified with O-linked β-N-acetylglucosamine (O-GlcNAc) contributes to cardiac protection. This study investigated the role of...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e31822fcede

    authors: Hirose K,Tsutsumi YM,Tsutsumi R,Shono M,Katayama E,Kinoshita M,Tanaka K,Oshita S

    更新日期:2011-11-01 00:00:00

  • Sympathetic responses to induction of anesthesia in humans with propofol or etomidate.

    abstract::Anesthetic induction with propofol commonly results in hypotension. This study explored potential mechanisms contributing to hypotension by recording cardiovascular responses including sympathetic neural activity from patients during induction of anesthesia with propofol (2.5 mg.kg-1 plus 200 micrograms.kg-1.min-1) or...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199205000-00010

    authors: Ebert TJ,Muzi M,Berens R,Goff D,Kampine JP

    更新日期:1992-05-01 00:00:00

  • Local versus central effect of halothane on carotid sinus baroreceptor function.

    abstract::Depressive effect of halothane on carotid sinus baroreceptor function may be due to direct local action, in the CNS, or both. Paris of dogs were anesthetized with pentobarbital and ventilated with oxygen. The carotid sinus of the recipient dog was isolated and perfused with blood from the common carotid artery of the ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198408000-00009

    authors: Behnia R,Koushanpour E

    更新日期:1984-08-01 00:00:00

  • Diphenylhydramine increases ventilatory drive during alfentanil infusion.

    abstract:BACKGROUND:Diphenhydramine is used as an antipruritic and antiemetic in patients receiving opioids. Whether it might exacerbate opioid-induced ventilatory depression has not been determined. METHODS:The ventilatory response to carbon dioxide during hyperoxia and the ventilatory response to hypoxia during hypercapnia (...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199809000-00013

    authors: Babenco HD,Blouin RT,Conard PF,Gross JB

    更新日期:1998-09-01 00:00:00

  • Effect of low-dose droperidol on the QT interval during and after general anesthesia: a placebo-controlled study.

    abstract:BACKGROUND:Since the effects of antiemetic doses of droperidol on the QT interval have not been previously studied, the authors designed a randomized, double-blind, placebo-controlled study to evaluate the intraoperative and postoperative effects of small-dose droperidol (0.625 and 1.25 mg intravenous) on the QT interv...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200506000-00007

    authors: White PF,Song D,Abrao J,Klein KW,Navarette B

    更新日期:2005-06-01 00:00:00

  • A single subanesthetic dose of ketamine relieves depression-like behaviors induced by neuropathic pain in rats.

    abstract:BACKGROUND:Chronic pain is associated with depression. In rodents, pain is often assessed by sensory hypersensitivity, which does not sufficiently measure affective responses. Low-dose ketamine has been used to treat both pain and depression, but it is not clear whether ketamine can relieve depression associated with c...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e31822f16ae

    authors: Wang J,Goffer Y,Xu D,Tukey DS,Shamir DB,Eberle SE,Zou AH,Blanck TJ,Ziff EB

    更新日期:2011-10-01 00:00:00

  • Comparison of the TOFscan and the TOF-Watch SX during Recovery of Neuromuscular Function.

    abstract:WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Quantitative neuromuscular monitoring is required to ensure neuromuscular function has recovered completely at the time of tracheal extubation. The TOFscan (Drager Technologies, Canada) is a new three-dimensional acceleromyograph...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0000000000002400

    authors: Murphy GS,Szokol JW,Avram MJ,Greenberg SB,Shear TD,Deshur M,Benson J,Newmark RL,Maher CE

    更新日期:2018-11-01 00:00:00

  • Epidural, cerebrospinal fluid, and plasma pharmacokinetics of epidural opioids (part 1): differences among opioids.

    abstract:BACKGROUND:The pharmacokinetics of epidurally administered drugs has been the subject of many studies, yet drug concentration in the epidural space has never been measured. This study was undertaken to characterize the epidural, cerebrospinal fluid, and plasma pharmacokinetics of epidurally administered opioids on the ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200308000-00029

    authors: Bernards CM,Shen DD,Sterling ES,Adkins JE,Risler L,Phillips B,Ummenhofer W

    更新日期:2003-08-01 00:00:00

  • Excitatory synaptic transmission mediated by NMDA receptors is more sensitive to isoflurane than are non-NMDA receptor-mediated responses.

    abstract:BACKGROUND:Effects of volatile anesthetic agents on N-methyl-D-aspartate (NMDA) receptor-mediated excitatory synaptic transmission have not been well characterized. The authors compared effects produced by halothane and isoflurane on electrophysiologic properties of NMDA and non-NMDA receptor-mediated synaptic response...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200001000-00035

    authors: Nishikawa K,MacIver MB

    更新日期:2000-01-01 00:00:00

  • Exercise produces sensitivity to metocurine.

    abstract::Chronic muscle disuse decreases the sensitivity of skeletal muscle to nondepolarizing relaxants, such as metocurine (MTC). In this study, the authors determined whether chronic conditioning would produce the opposite effect and increase the sensitivity of skeletal muscle to MTC. Five dogs were exercised by daily runni...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198906000-00015

    authors: Gronert GA,White DA,Shafer SL,Matteo RS

    更新日期:1989-06-01 00:00:00

  • Positive end-expiratory pressure ventilation elicits increases in endogenously formed nitric oxide as detected in air exhaled by rabbits.

    abstract:BACKGROUND:Nitric oxide (NO) formed from L-arginine is exhaled by mammals and regulates pulmonary vascular tone. Little is known about how its formation is stimulated. METHODS:The concentration of NO in exhaled air was monitored by chemiluminescence in pentobarbital-anesthetized rabbits receiving mechanical ventilatio...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199504000-00021

    authors: Persson MG,Lönnqvist PA,Gustafsson LE

    更新日期:1995-04-01 00:00:00

  • Comparison of the effects of etomidate, propofol, and thiopental on respiratory resistance after tracheal intubation.

    abstract:BACKGROUND:Tracheal intubation frequently results in reversible bronchoconstriction. Propofol has been reported to minimize this response in healthy patients and in asthma patients, but may be unsuitable for hemodynamically unstable patients for whom etomidate may be preferable. The current study examined respiratory r...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-199606000-00005

    authors: Eames WO,Rooke GA,Wu RS,Bishop MJ

    更新日期:1996-06-01 00:00:00

  • Isoflurane causes endothelium-dependent inhibition of contractile responses of canine coronary arteries.

    abstract::The authors sought to determine if isoflurane would attenuate effects of three different types of vasoconstrictors on isolated segments of canine epicardial coronary arteries removed from healthy dogs. As the endothelium has a major role in regulating epicardial coronary artery tone, and as it modulates the effect of ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198710000-00012

    authors: Blaise G,Sill JC,Nugent M,Van Dyke RA,Vanhoutte PM

    更新日期:1987-10-01 00:00:00

  • Association between Neuraxial Labor Analgesia and Neonatal Morbidity after Operative Vaginal Delivery.

    abstract:BACKGROUND:Up to 84% of women who undergo operative vaginal delivery receive neuraxial analgesia. However, little is known about the association between neuraxial analgesia and neonatal morbidity in women who undergo operative vaginal delivery. The authors hypothesized that neuraxial analgesia is associated with a redu...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0000000000003589

    authors: Butwick AJ,Wong CA,Lee HC,Blumenfeld YJ,Guo N

    更新日期:2021-01-01 00:00:00

  • Effect of oxygen treatment on heart rate after abdominal surgery.

    abstract:BACKGROUND:Cardiac complications are common during the postoperative period and may be associated with hypoxemia and tachycardia. Preliminary studies in high-risk patients after operation have shown a possible beneficial effect of oxygen therapy on arterial oxygen saturation and heart rate. METHODS:The authors studied...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-199902000-00008

    authors: Rosenberg-Adamsen S,Lie C,Bernhard A,Kehlet H,Rosenberg J

    更新日期:1999-02-01 00:00:00

  • Functional brain imaging during anesthesia in humans: effects of halothane on global and regional cerebral glucose metabolism.

    abstract:BACKGROUND:Propofol and isoflurane anesthesia were studied previously with functional brain imaging in humans to begin identifying key brain areas involved with mediating anesthetic-induced unconsciousness. The authors describe an additional positron emission tomography study of halothane's in vivo cerebral metabolic e...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199903000-00011

    authors: Alkire MT,Pomfrett CJ,Haier RJ,Gianzero MV,Chan CM,Jacobsen BP,Fallon JH

    更新日期:1999-03-01 00:00:00

  • Electroencephalogram approximate entropy correctly classifies the occurrence of burst suppression pattern as increasing anesthetic drug effect.

    abstract:BACKGROUND:Approximate entropy, a measure of signal complexity and regularity, quantifies electroencephalogram changes during anesthesia. With increasing doses of anesthetics, burst-suppression patterns occur. Because of the high-frequency bursts, spectrally based parameters such as median electroencephalogram frequenc...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000542-200010000-00018

    authors: Bruhn J,Röpcke H,Rehberg B,Bouillon T,Hoeft A

    更新日期:2000-10-01 00:00:00

  • Effects of halothane on the sarcoplasmic reticulum Ca2+ stores and contractile proteins in rabbit pulmonary arteries.

    abstract:BACKGROUND:The authors' purpose of this study was to elucidate the mechanisms of direct effects of halothane on the contractile proteins and Ca2+ release from the sarcoplasmic reticulum Ca2+ stores using isolated skinned strips (sarcolemma permealized with saponin) from rabbit pulmonary arteries. METHODS:The sarcoplas...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199804000-00031

    authors: Su JY,Tang LJ

    更新日期:1998-04-01 00:00:00

  • Influence of methylenetetrahydrofolate reductase gene polymorphisms on homocysteine concentrations after nitrous oxide anesthesia.

    abstract:BACKGROUND:Mutations in the methylenetetrahydrofolate reductase (MTHFR) gene (677C>T, 1298A>C) cause elevated plasma homocysteine concentrations and have been linked to fatal outcomes after nitrous oxide anesthesia. This study tested the hypothesis that patients with common MTHFR 677C>T or 1298A>C mutations develop hig...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e318178820b

    authors: Nagele P,Zeugswetter B,Wiener C,Burger H,Hüpfl M,Mittlböck M,Födinger M

    更新日期:2008-07-01 00:00:00

  • Sensitization of spinal neurons by non-noxious stimuli in the awake but not anesthetized state.

    abstract:BACKGROUND:The observation that peripheral trauma causes enhanced spinal neuronal excitability has provided the scientific rationale for the concept of "pre-emptive analgesia." The premise has been that only noxious stimuli cause sensitization in sensory pathways, but this premise has not been tested in the conscious s...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199501000-00032

    authors: Herrero JF,Headley PM

    更新日期:1995-01-01 00:00:00

  • Internal carotid artery stump pressure and cerebral blood flow during carotid endarterectomy: modification by halothane, enflurane, and innovar.

    abstract::Carotid endarterectomy requires temporary surgical occlusion of the involved carotid artery. During occlusion, the minimally acceptable (critical) internal carotid artery stump pressure is reported to be 50 torr, whereas for regional cerebral blood flow (rCBF), a critical range is reported to be 18-24 ml/100 g/min. Du...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-197610000-00007

    authors: McKay RD,Sundt TM,Michenfelder JD,Gronert GA,Messick JM,Sharbrough FW,Piepgras DG

    更新日期:1976-10-01 00:00:00

  • Spinal and systemic action of the alpha 2 receptor agonist dexmedetomidine in dogs. Antinociception and carbon dioxide response.

    abstract:BACKGROUND:alpha 2 Agonists are powerful analgesics after spinal delivery. The current work characterizes the dose-dependent antinociception and effects upon respiratory function of dexmedetomidine after intrathecal, epidural, intravenous, and intracisternal delivery in chronically prepared dogs. METHODS:Dogs were pre...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199405000-00015

    authors: Sabbe MB,Penning JP,Ozaki GT,Yaksh TL

    更新日期:1994-05-01 00:00:00

  • Epidural Labor Analgesia-Fentanyl Dose and Breastfeeding Success: A Randomized Clinical Trial.

    abstract:BACKGROUND:Breastfeeding is an important public health concern. High cumulative doses of epidural fentanyl administered for labor analgesia have been reported to be associated with early termination of breastfeeding. We tested the hypothesis that breastfeeding success is adversely influenced by the cumulative epidural ...

    journal_title:Anesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/ALN.0000000000001793

    authors: Lee AI,McCarthy RJ,Toledo P,Jones MJ,White N,Wong CA

    更新日期:2017-10-01 00:00:00

  • Aquaporin 5 -1364A/C Promoter Polymorphism Is Associated with Pulmonary Inflammation and Survival in Acute Respiratory Distress Syndrome.

    abstract:WHAT WE ALREADY KNOW ABOUT THIS TOPIC:Acute respiratory distress syndrome is defined according to clinical criteria, but lack of precise characterization may contribute to negative trials and impede personalized care. Polymorphisms of aquaporin-5, a key mediator of inflammation, may impact outcome. WHAT THIS ARTICLE T...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0000000000002560

    authors: Rahmel T,Rump K,Peters J,Adamzik M

    更新日期:2019-03-01 00:00:00

  • Epidural clonidine treatment for refractory reflex sympathetic dystrophy.

    abstract:BACKGROUND:Intraspinally administered alpha 2-adrenergic agonists may relieve pain in sympathetically maintained pain (SMP) syndromes, such as reflex sympathetically dystrophy (RSD), by spinal, peripheral, and central nervous system actions. This study examined analgesic efficacy and side effects of epidurally administ...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Rauck RL,Eisenach JC,Jackson K,Young LD,Southern J

    更新日期:1993-12-01 00:00:00

  • Intrathecal sufentanil for labor analgesia does not cause a sympathectomy.

    abstract:BACKGROUND:Intrathecal sufentanil (ITS) is frequently used to provide analgesia during labor. Decreases in blood pressure and sensory changes in this circumstance suggest that ITS may have a local anesthetic effect and thus cause a sympathectomy. To determine whether ITS given to laboring women causes a sympathectomy, ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199710000-00022

    authors: Riley ET,Walker D,Hamilton CL,Cohen SE

    更新日期:1997-10-01 00:00:00

  • Mechanism of myocardial protection by isoflurane. Role of adenosine triphosphate-regulated potassium (KATP) channels.

    abstract:BACKGROUND:The mechanism of the protective actions of volatile anesthetics in ischemic myocardium has not been clearly elucidated. The role of myocardial adenosine triphosphate-regulated potassium (KATP) channels in isoflurane-induced enhancement of recovery of regional contractile function after multiple brief occlusi...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199610000-00015

    authors: Kersten JR,Schmeling TJ,Hettrick DA,Pagel PS,Gross GJ,Warltier DC

    更新日期:1996-10-01 00:00:00

  • Blood Purification and Mortality in Sepsis and Septic Shock: A Systematic Review and Meta-analysis of Randomized Trials.

    abstract:BACKGROUND:Sepsis and septic shock are severe inflammatory conditions related to high morbidity and mortality. We performed a systematic review with meta-analysis of randomized trials to assess whether extracorporeal blood purification reduces mortality in this setting. METHODS:Electronic databases were searched for p...

    journal_title:Anesthesiology

    pub_type: 杂志文章,meta分析

    doi:10.1097/ALN.0000000000002820

    authors: Putzu A,Schorer R,Lopez-Delgado JC,Cassina T,Landoni G

    更新日期:2019-09-01 00:00:00

  • Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes.

    abstract:BACKGROUND:Potentiation by general anesthetics of gamma-aminobutyric acid (GABA)-mediated inhibitory transmission in the central nervous system is attributed to GABA(A) receptor-mediated postsynaptic effects. However, the role of presynaptic mechanisms in general anesthetic action is not well characterized, and evidenc...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199810000-00017

    authors: Murugaiah KD,Hemmings HC Jr

    更新日期:1998-10-01 00:00:00

  • Cardiovascular events in the postanesthesia care unit: contribution of risk factors.

    abstract:BACKGROUND:The purpose of this study was to determine the relationship of four postanesthesia care unit (PACU) cardiovascular events to long-term outcomes (unplanned critical care admission or mortality) and to evaluate the contribution of anesthetic management compared with other perioperative factors in predicting th...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199604000-00003

    authors: Rose DK,Cohen MM,DeBoer DP

    更新日期:1996-04-01 00:00:00