Sensitization of spinal neurons by non-noxious stimuli in the awake but not anesthetized state.

abstract：BACKGROUND:The results of sevoflurane biotransformation (fluoromethyl-1,1,1,3,3,3,-hexafluoro-2-propyl ether) to inorganic fluoride have been examined. However, these investigations have lacked a simplified assay for determining the primary organic metabolite, hexafluoroisopropanol. Previous attempts have involved exte...

journal_title：Anesthesiology

authors： Morgan SE,Frink EJ,Gandolfi AJ

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Patient blood management combines the use of several transfusion alternatives. Integrated use of erythropoietin, cell saver, and/or postoperative drain reinfusion devices on allogeneic erythrocyte use was evaluated using a restrictive transfusion threshold. METHODS:In a factorial design, adult elective hip-...

journal_title：Anesthesiology

authors： So-Osman C,Nelissen RG,Koopman-van Gemert AW,Kluyver E,Pöll RG,Onstenk R,Van Hilten JA,Jansen-Werkhoven TM,van den Hout WB,Brand R,Brand A

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Perioperative thoracic epidural analgesia reduces stress response and pain scores and may improve outcome after cardiac surgery. This prospective, randomized trial was designed to compare the effectiveness of patient-controlled thoracic epidural analgesia with patient-controlled analgesia with intravenous mo...

journal_title：Anesthesiology

authors： Hansdottir V,Philip J,Olsen MF,Eduard C,Houltz E,Ricksten SE

更新日期：2006-01-01 00:00:00

abstract：:To assess the effect of a glucose infusion on brain extracellular fluid (ECF) during systemic hypoxia, changes in glucose and lactate concentrations in cerebral ECF during and after moderate hypoxic hypoxia were measured in adult, conscious, unrestrained rats, with a microdialysis probe in the posterior hippocampus. T...

journal_title：Anesthesiology

authors： Harada M,Okuda C,Sawa T,Murakami T

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:The lightwand may be useful as an alternative for tracheal intubation during a rapid-sequence induction of anesthesia in the presence of a full stomach. This study was undertaken to assess the effect of application of cricoid pressure on the success of lightwand intubation. METHODS:Sixty adult female patien...

journal_title：Anesthesiology

authors： Hodgson RE,Gopalan PD,Burrows RC,Zuma K

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:The volatile anesthetic isoflurane reduces acute and delayed neuron death in vitro models of brain ischemia, an action that the authors hypothesize is related to moderate increases in intracellular calcium concentration ([Ca2+]i). Specifically, the authors propose that during hypoxia, moderate increases in [...

journal_title：Anesthesiology

authors： Gray JJ,Bickler PE,Fahlman CS,Zhan X,Schuyler JA

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Kinins (e.g., bradykinin) acting through the constitutively expressed B2 and the injury-induced B1 receptors are involved in pain and hyperalgesia, as previously shown by use of receptor-selective antagonists and single-receptor knockout models. Because the overall contribution of kinins to painful processes...

journal_title：Anesthesiology

authors： Cayla C,Labuz D,Machelska H,Bader M,Schäfer M,Stein C

更新日期：2012-02-01 00:00:00

abstract：:The influence of isoflurane on membrane currents, action potentials, and contraction was investigated in single cells isolated from guinea-pig ventricle. Isoflurane (1.65-4.45%) reduced the action potential duration at 20% and 90% repolarization times. When step depolarizations were applied under voltage-clamp conditi...

journal_title：Anesthesiology

authors： Terrar DA,Victory JG

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:The Neurologic and Adaptive Capacity Score (NACS) is a multi-item scale that was published in 1982 to measure the effects of intrapartum drugs on the neonate. Although this scoring system has been widely used in obstetric anesthesia research, studies confirming its reliability have not been published. The pu...

journal_title：Anesthesiology

authors： Halpern SH,Littleford JA,Brockhurst NJ,Youngs PJ,Malik N,Owen HC

更新日期：2001-06-01 00:00:00

abstract：:Low concentrations of ethanol (17 mM) inhibited development of spontaneous mechanical activity (vasomotion) in isolated rat portal veins. Low concentrations of ethanol potentiated, however, contractions induced by epinephrine, but not those induced by angiotensin or potassium. Higher concentrations of ethanol, such as...

journal_title：Anesthesiology

authors： Edgarian H,Altura BM

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:Clonidine, an alpha 2-adrenoceptor agonist, has been shown to be effective as a preanesthetic medication in adults. The current study was designed to investigate the efficacy of two doses of oral clonidine as a premedicant preceding oral atropine in children. METHODS:In a prospective, randomized, double-bli...

journal_title：Anesthesiology

authors： Mikawa K,Maekawa N,Nishina K,Takao Y,Yaku H,Obara H

更新日期：1993-11-01 00:00:00

abstract：:Critically ill patients must often breathe spontaneously through an endotracheal tube that acts as a fixed inspiratory and expiratory tubular airway resistor. Although this practice is common, its effect on the pattern of breathing is not known. The mean breathing patterns of seven normal, healthy male subjects and ei...

journal_title：Anesthesiology

authors： Weissman C,Askanazi J,Rosenbaum SH,Damask MC,Hyman AI,Kinney JM

更新日期：1986-03-01 00:00:00

abstract：:Depressive effect of halothane on carotid sinus baroreceptor function may be due to direct local action, in the CNS, or both. Paris of dogs were anesthetized with pentobarbital and ventilated with oxygen. The carotid sinus of the recipient dog was isolated and perfused with blood from the common carotid artery of the ...

journal_title：Anesthesiology

authors： Behnia R,Koushanpour E

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:The diagnosis of acute life-threatening allergic reactions during anesthesia relies on clinical signs, histamine and/or tryptase measurements, and allergic testing. In patients who die after the reaction, skin tests cannot be performed, and the effect of resuscitation manoeuvres on mediator concentrations is...

journal_title：Anesthesiology

authors： Laroche D,Gomis P,Gallimidi E,Malinovsky JM,Mertes PM

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Previously, the authors found that anesthetized diabetic dogs had increased cerebral blood flow (CBF) and oxygen consumption (CMRO2). These results may have been influenced by anesthesia or surgery. The aim of this study was to determine whether CBF and CMRO2 are increased in the awake or anesthetized state ...

journal_title：Anesthesiology

authors： Sieber FE,Brown PR,Wu Y,Koehler RC,Traystman RJ

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The authors' objective was to assess the role of protein kinase C (PKC) and nitric oxide synthase (NOS) in mediating the effects of propofol on diabetic cardiomyocyte contractility, intracellular free Ca2+ concentration ([Ca2+]i), and myofilament Ca2+ sensitivity. METHODS:Freshly isolated ventricular myocyt...

journal_title：Anesthesiology

authors： Wickley PJ,Shiga T,Murray PA,Damron DS

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine is an alpha 2 agonist with potential utility in clinical anesthesia for both its sedative and sympatholytic properties. METHODS:The pharmacokinetics and hemodynamic changes that occurred in ten healthy male volunteers were determined after administration of dexmedetomidine 2 micrograms/kg by...

journal_title：Anesthesiology

authors： Dyck JB,Maze M,Haack C,Vuorilehto L,Shafer SL

更新日期：1993-05-01 00:00:00

abstract：:The safety and efficacy of epidural morphine injected into the caudal space for control of postoperative pain following open cardiac surgery in children was studied. Thirty-two children between the ages of 2-12 yr for whom early postoperative tracheal extubation was anticipated were randomly assigned to control and st...

journal_title：Anesthesiology

authors： Rosen KR,Rosen DA

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Isoflurane anesthesia produces cardiovascular and respiratory depression, although the specific mechanisms are not fully understood. Cranial visceral afferents, which innervate the heart and lungs, synapse centrally onto neurons within the medial portion of the nucleus tractus solitarius (NTS). Isoflurane mo...

journal_title：Anesthesiology

authors： Peters JH,McDougall SJ,Mendelowitz D,Koop DR,Andresen MC

更新日期：2008-04-01 00:00:00

abstract：:The effects of epinephrine 1/200,000 as an adjuvant to epidural morphine were investigated in three healthy male volunteers, during 26-h observation sessions. Peak blood concentrations of morphine were 44 +/- 12.9 ng/ml after plain morphine and 13.7 +/- 6.7 ng/ml after epinephrine-morphine. Cutaneous hypalgesia was mo...

journal_title：Anesthesiology

authors： Bromage PR,Camporesi EM,Durant PA,Nielsen CH

更新日期：1983-03-01 00:00:00

abstract：:Malpractice claims filed against anesthesiologists for care involving obstetric (OB) anesthesia (n = 190) were taken from the American Society of Anesthesiologists' Closed Claims Database and compared to claims not involving OB cases (n = 1351). The most common complications in the OB claims were (percentage of all OB...

journal_title：Anesthesiology

authors： Chadwick HS,Posner K,Caplan RA,Ward RJ,Cheney FW

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:The effects of propofol, remifentanil, and their combination on phrenic nerve activity (PNA), resting heart rate (HR), mean arterial pressure (MAP), and nociceptive cardiovascular responses were studied in rabbits. METHODS:Basal anesthesia and constant blood gas tensions were maintained with alpha-chloralos...

journal_title：Anesthesiology

authors： Ma D,Chakrabarti MK,Whitwam JG

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:This study aimed to characterize the electroencephalogram in children who emerged with emergence delirium (ED) compared with children without ED using methods that involved the assessment of cortical functional connectivity. METHODS:Children aged 5 to 15 yr had multichannel electroencephalographic recording...

journal_title：Anesthesiology

authors： Martin JC,Liley DT,Harvey AS,Kuhlmann L,Sleigh JW,Davidson AJ

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The value of exercise electrocardiography in the prediction of perioperative cardiac risk has yet to be defined. This study was performed to determine the predictive value of exercise electrocardiography as compared with clinical parameters and resting electrocardiography. METHODS:A total of 204 patients at...

journal_title：Anesthesiology

authors： Gauss A,Röhm HJ,Schäuffelen A,Vogel T,Mohl U,Straehle A,Meierhenrich R,Georgieff M,Steinbach G,Schütz W

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Sweating, vasoconstriction, and shivering have been observed during general anesthesia. Among these, vasoconstriction is especially important because-once triggered-it minimizes further hypothermia. Surprisingly, the core-temperature plateau associated with vasoconstriction appears to preserve core temperatu...

journal_title：Anesthesiology

authors： Plattner O,Semsroth M,Sessler DI,Papousek A,Klasen C,Wagner O

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:The authors conducted a randomized, controlled, parallel-arm, superiority study to test the hypothesis that a continuous adductor canal block decreases the time to attain four discharge criteria compared with a continuous femoral nerve block after tricompartment knee arthroplasty. METHODS:Subjects undergoin...

journal_title：Anesthesiology

authors： Machi AT,Sztain JF,Kormylo NJ,Madison SJ,Abramson WB,Monahan AM,Khatibi B,Ball ST,Gonzales FB,Sessler DI,Mascha EJ,You J,Nakanote KA,Ilfeld BM

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Spontaneous breaths during airway pressure release ventilation (APRV) have to overcome the resistance of the artificial airway. Automatic tube compensation provides ventilatory assistance by increasing airway pressure during inspiration and lowering airway pressure during expiration, thereby compensating for...

journal_title：Anesthesiology

authors： Wrigge H,Zinserling J,Hering R,Schwalfenberg N,Stüber F,von Spiegel T,Schroeder S,Hedenstierna G,Putensen C

更新日期：2001-08-01 00:00:00

abstract：:To determine the minimum alveolar concentration (MAC) and hemodynamic responses to halothane, isoflurane, and sevoflurane in newborn swine, 36 fasting swine 4-10 days of age were anesthetized with one of the three volatile anesthetics in 100% oxygen. MAC was determined for each swine. Carotid artery and internal jugul...

journal_title：Anesthesiology

authors： Lerman J,Oyston JP,Gallagher TM,Miyasaka K,Volgyesi GA,Burrows FA

更新日期：1990-10-01 00:00:00

abstract：:The relationship between the extent of preoperative beta-adrenoceptor blockade and the hemodynamic properties of dobutamine was investigated in patients scheduled for elective myocardial revascularization during isoflurane-nitrous oxide anesthesia. Twenty patients had been treated with beta-adrenoceptor blocking drugs...

journal_title：Anesthesiology

authors： Tarnow J,Komar K

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Emergence delirium has been investigated in several clinical trials. However, no reliable and valid rating scale exists to measure this phenomenon in children. Therefore, the authors developed and evaluated the Pediatric Anesthesia Emergence Delirium (PAED) scale to measure emergence delirium in children. M...

journal_title：Anesthesiology

authors： Sikich N,Lerman J

更新日期：2004-05-01 00:00:00