Postoperative cognitive dysfunction in patients with preoperative cognitive impairment: which domains are most vulnerable?

abstract：BACKGROUND:Use of high-dose inhalational anesthesia during open fetal surgery may induce maternal-fetal hemodynamic instability and fetal myocardial depression. The authors' preliminary human retrospective study demonstrated less fetal bradycardia and left ventricular systolic dysfunction with lower dose desflurane sup...

journal_title：Anesthesiology

authors： Ngamprasertwong P,Michelfelder EC,Arbabi S,Choi YS,Statile C,Ding L,Boat A,Eghtesady P,Holland K,Sadhasivam S

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The authors tested the hypothesis that pretreatment with isoflurane or sevoflurane can protect the heart against neutrophil-induced contractile dysfunction. METHODS:Studies were conducted in buffer-perfused and paced isolated rat hearts. Left ventricular developed pressure served as an index of contractilit...

journal_title：Anesthesiology

authors： Hu G,Salem MR,Crystal GJ

更新日期：2004-03-01 00:00:00

abstract：:Isoflurane has a lesser ability than halothane to induce contracture in malignant hyperthermia (MH) muscle in vitro. This does not necessarily imply that isoflurane is not as potent an MH trigger as halothane in vivo. A hypothesis was tested that in vitro treatment with Bay K 8644, an activator of both the dihydropyri...

journal_title：Anesthesiology

authors： Adnet PJ,Krivosic-Horber RM,Adamantidis MM,Haudecoeur G,Reyford H,Imbenotte M

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:An initial pilot study of 300 sub-Tenon local anesthetic blocks (STBs) for intraocular surgery established the effectiveness and patient acceptability of the technique. Following this, a decision was made in 1995 to change from sharp needle techniques to STB for all eye surgeries performed during local anest...

journal_title：Anesthesiology

authors： Guise PA

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Oral gabapentin is approved as an anticonvulsant medication and to treat postherpetic neuralgia. Its nonopioid properties and presumed spinal site of analgesic action made the study on intrathecal gabapentin attractive to establish the minimum effective dose for a later, pivotal trial. METHODS:The authors e...

journal_title：Anesthesiology

authors： Rauck R,Coffey RJ,Schultz DM,Wallace MS,Webster LR,McCarville SE,Grigsby EJ,Page LM

更新日期：2013-09-01 00:00:00

abstract：:To determine whether administration of nitrous oxide, 50% and 70%, could provide analgesia and anxiolysis during venous cannulation in pediatric patients, 165 ASA Physical Status 1 patients scheduled for elective surgery were studied. Children, 3 weeks to 18 yr of age, were randomly assigned either to receive nitrous ...

journal_title：Anesthesiology

authors： Henderson JM,Spence DG,Komocar LM,Bonn GE,Stenstrom RJ

更新日期：1990-02-01 00:00:00

abstract：:The need for accurate clinical diagnosis and appropriate intervention requires that a modern blood-gas laboratory have the means to correct for significant discrepancies between patient temperature and the temperature at which in vitro blood samples are analyzed. Recent advances in mini- and microcomputer technology p...

journal_title：Anesthesiology

authors： Andritsch RF,Muravchick S,Gold MI

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:The pharmacokinetics and pharmacodynamics of succinylcholine were studied simultaneously in anesthetized patients to understand why the drug has a rapid onset and short duration of action. A quantitative model describing the concentration-effect relation of succinylcholine was proposed. The correlation betwe...

journal_title：Anesthesiology

authors： Roy JJ,Donati F,Boismenu D,Varin F

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Drugs that block spinal excitatory amino acid receptor activation may prevent pain after surgery. The authors previously studied the effect of excitatory amino acid receptor antagonists after incision. In the present study, we examined the role of N-methyl-d-aspartate (NMDA), non-NMDA, and metabotropic gluta...

journal_title：Anesthesiology

authors： Pogatzki EM,Zahn PK,Brennan TJ

更新日期：2000-08-01 00:00:00

abstract：:Interposition of activated carbon between a nitrogen analyzer needle valve and gas mixtures containing halothane, methoxyflurane, enflurane, or isoflurane eliminated the interfering effects of these agents, but added sampling delays. Placement of a carbon-filled Swinney adaptor in the sampling line between the needle ...

journal_title：Anesthesiology

authors： Gilmour IJ,Holland R,Craig DB

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Diaphragm and psoas are affected during sepsis in animal models. Whether diaphragm or limb muscle is preferentially affected during sepsis in the critically ill remains unclear. METHODS:Retrospective secondary analysis study including 40 patients, comparing control (n = 17) and critically ill patients, with...

journal_title：Anesthesiology

authors： Jung B,Nougaret S,Conseil M,Coisel Y,Futier E,Chanques G,Molinari N,Lacampagne A,Matecki S,Jaber S

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Acid aspiration into one lung causes contralateral lung injury and systemic organ injury; this injury is thought to be mediated by the sequestration of activated neutrophils. Recombinant human soluble complement receptor 1 (sCR1) inhibits both the classical and alternative complement pathways; this study inv...

journal_title：Anesthesiology

authors： Nishizawa H,Yamada H,Miyazaki H,Ohara M,Kaneko K,Yamakawa T,Wiener-Kronish J,Kudoh I

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Patients with initial mild acute respiratory distress syndrome are often underrecognized and mistakenly considered to have low disease severity and favorable outcomes. They represent a relatively poorly characterized population that was only classified as having acute respiratory distress syndrome in the mos...

journal_title：Anesthesiology

authors： Pham T,Serpa Neto A,Pelosi P,Laffey JG,De Haro C,Lorente JA,Bellani G,Fan E,Brochard LJ,Pesenti A,Schultz MJ,Artigas A,LUNG SAFE Investigators* and the European Society of Intensive Care Medicine Trials Group.

更新日期：2019-02-01 00:00:00

abstract：:The effects of halothane on uptake and phosphorylation of uridine, and on cellular ATP content were studied in Tetrahymena pyriformis, a ciliate protozoan. Exposure to halothane inhibited the accumulation of 14C-uridine into the following acid-soluble intracellular pools: UTP, UDP, UMP, and an unidentified compound. H...

journal_title：Anesthesiology

authors： Conklin KA,Lau SS

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Propofol and alfentanil frequently are administered together for intravenous sedation. This study investigated pharmacokinetic and pharmacodynamic interactions between propofol and alfentanil, at sedative concentrations, with specific regard to effects on ventilation, analgesia, sedation, and nausea. METHOD...

journal_title：Anesthesiology

authors： Pavlin DJ,Coda B,Shen DD,Tschanz J,Nguyen Q,Schaffer R,Donaldson G,Jacobson RC,Chapman CR

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Patients with brain injury are at high risk of extubation failure. METHODS:We conducted a prospective observational cohort study in four intensive care units of three university hospitals. The aim of the study was to create a score that could predict extubation success in patients with brain injury. RESULT...

journal_title：Anesthesiology

authors： Asehnoune K,Seguin P,Lasocki S,Roquilly A,Delater A,Gros A,Denou F,Mahé PJ,Nesseler N,Demeure-Dit-Latte D,Launey Y,Lakhal K,Rozec B,Mallédant Y,Sébille V,Jaber S,Le Thuaut A,Feuillet F,Cinotti R,ATLANREA group.

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Dysrhythmias and death occur in patients with acquired long QT syndrome (LQTS). Little information exists regarding interactions between anesthetics and drugs that prolong ventricular repolarization. Therefore the effects of three commonly used intravenous anesthetics on ventricular repolarization were inves...

journal_title：Anesthesiology

authors： Morey TE,Martynyuk AE,Napolitano CA,Raatikainen MJ,Guyton TS,Dennis DM

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:No externally validated risk score for postoperative pulmonary complications (PPCs) is currently available. The authors tested the generalizability of the Assess Respiratory Risk in Surgical Patients in Catalonia risk score for PPCs in a large European cohort (Prospective Evaluation of a RIsk Score for posto...

journal_title：Anesthesiology

authors： Mazo V,Sabaté S,Canet J,Gallart L,de Abreu MG,Belda J,Langeron O,Hoeft A,Pelosi P

更新日期：2014-08-01 00:00:00

abstract：:Groups of rats were exposed to air or 80 per cent nitrous oxide for 30 min or 18 h, following which the brainstem opiate receptor density and the apparent affinity of these receptors to the radiolabeled agonist, 3H-dihydromorphine, were assayed, Thirty-minute exposure to nitrous oxide did not change opiate receptor ch...

journal_title：Anesthesiology

authors： Ngai SH,Finck AD

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Glucocorticoids have been reported to aggravate ischemic brain damage. Because changes in the activities of various neuronal systems are closely related to the outcome of ischemic damage, the authors evaluated the effects of dexamethasone on the monoaminergic systems and ischemic neuronal damage. METHODS:Th...

journal_title：Anesthesiology

authors： Tsubota S,Adachi N,Chen J,Yorozuya T,Nagaro T,Arai T

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The use of nicotinic agonists for analgesia is limited by their unacceptable side effects. Sazetidine-A is a new partial agonist nicotinic ligand that has very high selectivity for beta2-containing nicotinic acetylcholine receptors. It potently and selectively desensitizes alpha4beta2 nicotinic acetylcholine...

journal_title：Anesthesiology

authors： Cucchiaro G,Xiao Y,Gonzalez-Sulser A,Kellar KJ

更新日期：2008-09-01 00:00:00

abstract：:The solutions to the problems of medical malpractice and malpractice insurance coverage are primarily in the hands of state legislatures. Legislation enacted has been primarily palliative, to assure continued availability of professional liability insurance. Unfortunately, no limit can be placed on the costs of such c...

journal_title：Anesthesiology

authors： Dornette WH

更新日期：1976-03-01 00:00:00

abstract：:The pattern of breathing and lung mechanics were evaluated during the first 7 h of life in full-term healthy newborns delivered by cesarean section with bupivacaine epidural anesthesia, without (group 1) or with the addition of 100 micrograms of fentanyl (group 2). Respiration and oxyhemoglobin saturation (SpO2) were ...

journal_title：Anesthesiology

authors： Benlabed M,Dreizzen E,Ecoffey C,Escourrou P,Migdal M,Gaultier C

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Patients who are homozygous for the atypical mutation, compound heterozygous for atypical and silent mutations, or homozygous for silent mutations (SS) respond to mivacurium with extensively prolonged neuromuscular block. Although important, exact phenotyping of these patients is difficult. This article pres...

journal_title：Anesthesiology

authors： Gätke MR,Ostergaard D,Bundgaard JR,Varin F,Viby-Mogensen J

更新日期：2001-09-01 00:00:00

abstract：:The effect of halothane on the pressor responses to hypoxia (3% O2, 5% CO2, balance N2) and to Angiotensin II (Ang II) (0.2 microgram) has been compared in an in vitro perfused and ventilated rat lung preparation in the presence and absence of agents known to block the lipoxygenase (BW755C) and/or the cyclooxygenase (...

journal_title：Anesthesiology

authors： Marshall C,Kim SD,Marshall BE

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Oral clonidine may influence plasma glucose and lipid homeostasis by modulating endocrinologic responses to surgical stress. The effect of oral clonidine premedication on plasma glucose and lipid homeostasis associated with exogenous glucose infusion were investigated in children undergoing minor surgery. M...

journal_title：Anesthesiology

authors： Nishina K,Mikawa K,Maekawa N,Shiga M,Obara H

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:The brain is assumed to be the site of anesthetic action, but anesthetics have effects elsewhere, such as the spinal cord. A preferentially anesthetized goat brain model was used to determine the importance of anesthetic action in the brain. METHODS:Six goats were anesthetized with isoflurane; after trachea...

journal_title：Anesthesiology

authors： Antognini JF,Schwartz K

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Although inhalation anesthetic agents are thought to impair cerebral autoregulation more than intravenous agents, there are few controlled studies in humans. METHODS:In the first group (n = 24), dynamic autoregulation was assessed from the response of middle cerebral artery blood flow velocity (Vmca) to a t...

journal_title：Anesthesiology

authors： Strebel S,Lam AM,Matta B,Mayberg TS,Aaslid R,Newell DW

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Halothane induces negative inotropic and lusitropic effects in myocardium. It has been suggested that halothane potentiates beta-adrenoceptor stimulation. However, its effects on the inotropic response to alpha-adrenoceptor stimulation and its effects on the lusitropic effects of alpha- and beta-adrenoceptor...

journal_title：Anesthesiology

authors： Hanouz JL,Riou B,Massias L,Lecarpentier Y,Coriat P

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:In spinal anesthesia, often a large interindividual variability in analgesic response is observed after administration of a certain fixed dose of anesthetic to a patient population. To improve therapeutic outcome it is important to characterize the variability in response by means of a population model (e.g....

journal_title：Anesthesiology

authors： Schnider TW,Minto CF,Bruckert H,Mandema JW

更新日期：1996-09-01 00:00:00