Intense aerobic exercise lowers blood pressure in individuals with metabolic syndrome taking antihypertensive medicine.

Abstract:

OBJECTIVE:There is a growing tendency for physicians to prescribe exercise in accordance with the 'exercise is medicine' global health initiative. However, the exercise-pharmacologic interactions for controlling blood pressure are not well described. Our purpose was to study whether angiotensin II receptor type 1 blocker (ARB) antihypertensive medicine enhances the blood pressure-lowering effects of intense exercise. PARTICIPANTS AND METHODS:Fifteen hypertensive individuals with metabolic syndrome chronically medicated with ARB underwent two exercise trials in a blind randomized order. One trial was conducted after taking their habitual dose of ARB (ARB MED trial) and another after 48 h of placebo medicine (i.e. dextrose; PLAC trial). RESULTS:After placebo medication, brachial systolic blood pressure increased by 5.5 mmHg [P=0.009; effect size (ES)=0.476] and diastolic by 2.5 mmHg (P=0.030; ES=0.373). Exercise reduced systolic and diastolic blood pressures to the same extent in ARB MED and PLAC trials (7 and 8 mmHg, respectively, for systolic and 5 and 4 mmHg, respectively, for diastolic, all P<0.05). Pulsatile measures of arterial stiffness did not reveal an interaction effect between exercise and medication. However, postocclusion reactive hyperemia increased after exercise only in the ARB MED trial (361±169 to 449±240% from baseline; P=0.033; ES=0.429). CONCLUSION:ARBs and a bout of intense exercise each have an independent effect on lowering blood pressure in hypertensive individuals, and these effects are additive.

journal_name

Blood Press Monit

authors

Ramirez-Jimenez M,Fernandez-Elias V,Morales-Palomo F,Ortega JF,Mora-Rodriguez R

doi

10.1097/MBP.0000000000000328

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

230-236

issue

5

eissn

1359-5237

issn

1473-5725

journal_volume

23

pub_type

杂志文章,随机对照试验
  • Performance of the automated BpTRU measurement device in the assessment of white-coat hypertension and white-coat effect.

    abstract:OBJECTIVES:BpTRU (VSM MedTech Ltd, Vancouver, Canada) is an automated oscillometric device that provides serial blood pressure measurements in an office setting in the absence of a healthcare professional. We sought to determine whether the white-coat effect is reduced by a blood pressure measurement protocol using BpT...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/01.mbp.0000189794.36230.a7

    authors: Culleton BF,McKay DW,Campbell NR

    更新日期:2006-02-01 00:00:00

  • Effect of bedtime melatonin ingestion on blood pressure of normotensive subjects.

    abstract::OBJECTIVE: To determine whether the evening intake of 5 mg melatonin affects 24 h arterial blood pressure and heart-rate profiles. METHODS: Twenty-one young normotensive subjects were administered placebo or melatonin for 4 weeks, according to a cross-over double-blind design, and were subjected to ambulatory blood pr...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:

    authors: Lusardi P,Preti P,Savino S,Piazza E,Zoppi A,Fogari R

    更新日期:1997-04-01 00:00:00

  • Automated office blood pressure - being alone and not location is what matters most.

    abstract:OBJECTIVE:Measurement of office blood pressure using a fully automated sphygmomanometer that takes multiple readings with the patient resting quietly alone has been called automated office blood pressure (AOBP). Almost all AOBP research has involved the patient resting alone in an examining room, which is often impract...

    journal_title:Blood pressure monitoring

    pub_type: 临床试验,杂志文章

    doi:10.1097/MBP.0000000000000133

    authors: Armstrong D,Matangi M,Brouillard D,Myers MG

    更新日期:2015-08-01 00:00:00

  • Blood pressure monitoring in sleep: time to wake up.

    abstract::Hypertension is a highly common condition with well-established adverse consequences. Ambulatory blood pressure monitoring has repeatedly been shown to better predict cardiovascular outcomes and mortality, compared to single office visit blood pressure. Non-dipping of sleep-time blood pressure is an independent marker...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章,评审

    doi:10.1097/MBP.0000000000000426

    authors: Kwon Y,Stafford PL,Lim DC,Park S,Kim SH,Berry RB,Calhoun DA

    更新日期:2020-04-01 00:00:00

  • Angiotensin II receptor blockers following intravenous nicardipine administration to lower blood pressure in patients with hypertensive intracerebral hemorrhage: a prospective randomized study.

    abstract:BACKGROUND AND OBJECTIVE:In patients with hypertensive intracerebral hemorrhage (HICH), intravenous nicardipine is primarily used to lower blood pressure (BP). However, there are few studies investigating the role of oral antihypertensives administered after intravenous nicardipine to prevent BP from rising. Angiotensi...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MBP.0000000000000225

    authors: Inamasu J,Nakae S,Adachi K,Hirose Y

    更新日期:2017-02-01 00:00:00

  • Is blunted heart rate decrease at night associated with prevalent organ damage in essential hypertension?

    abstract:AIM:The association between a blunted decrease in day–night heart rate and subclinical organ damage has not been investigated earlier in human hypertension. Therefore, we assessed such an association in a cohort of 658 untreated essential hypertensive patients. METHODS:All patients underwent procedures including cardi...

    journal_title:Blood pressure monitoring

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1097/mbp.0b013e32834331fe

    authors: Cuspidi C,Meani S,Negri F,Valerio C,Sala C,Mancia G

    更新日期:2011-02-01 00:00:00

  • Evaluation of two devices for self-measurement of blood pressure according to the international protocol: the Omron M5-I and the Omron 705IT.

    abstract:BACKGROUND:Two devices for self-measurement of blood pressure at the brachial artery-the Omron M5-I and the Omron 705IT-were evaluated according to the international protocol of the European Society of Hypertension. DESIGN:The international validation protocol is divided into two phases: the first phase is performed o...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/00126097-200306000-00006

    authors: El Assaad MA,Topouchian JA,Asmar RG

    更新日期:2003-06-01 00:00:00

  • Effect of fasting on 24-h blood pressure values of individuals with no previous history of hypertension.

    abstract:OBJECTIVE:We aimed to analyze the difference in 24-h blood pressure values during Ramadan of fasting and nonfasting individuals with no previous history of hypertension. PATIENTS AND METHODS:This study was planned as a multicenter research study in the cities of Izmit, Zonguldak, Sivas, and Adana. The percentage chang...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MBP.0000000000000244

    authors: Seker A,Demirci H,Ocakoglu G,Aydin U,Ucar H,Yildiz G,Yaman O

    更新日期:2017-10-01 00:00:00

  • Simultaneous validation of the SunTech 247 diagnostic station blood pressure measurement device according to the British Hypertension Society protocol, the International Protocol and the Association for the Advancement of Medical Instrumentation standards

    abstract:OBJECTIVE:SunTech 247 is an oscillometric blood pressure (BP) monitor manufactured by SunTech Medical Inc., Morrisville, North Carolina, USA. The aims of this study were (i) to determine its accuracy using the 1993 modified British Hypertension Society (BHS) protocol, the 2002 International Protocol (IP) and the 2002/2...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/MBP.0b013e328330c873

    authors: Polo Friz H,Facchetti R,Primitz L,Beltrame L,Galbiati V,Ricioppo A,Bombelli M,Sega R

    更新日期:2009-10-01 00:00:00

  • Validation of the Omron HEM-907 device for blood pressure measurement.

    abstract:BACKGROUND:The aim of this study was to validate the Omron HEM-907 blood pressure (BP) measuring device according to the international validation protocol. DESIGN:The international validation protocol is divided into two phases: the first phase is performed on 15 selected subjects and if the device passes this phase, ...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/00126097-200208000-00006

    authors: El Assaad MA,Topouchian JA,Darné BM,Asmar RG

    更新日期:2002-08-01 00:00:00

  • Percentiles of waist-to-sitting-height ratio and its relationship with obesity and elevated blood pressure among children and adolescents in Shandong, China.

    abstract:BACKGROUND:Waist circumference (WC) and related anthropometric indices have been recognized as useful measures of abdominal obesity. However, little is known about the association of waist-to-sitting-height ratio (WSHtR) with obesity and elevated blood pressure (BP). PARTICIPANTS AND METHODS:Data for this study were o...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/MBP.0000000000000154

    authors: Zhang YX,Zhao JS,Chu ZH

    更新日期:2016-02-01 00:00:00

  • The effect of crossing legs on blood pressure: a randomized single-blind cross-over study.

    abstract:BACKGROUND:Although there is a theoretical basis for crossing legs to increase blood pressure, there are no published data addressing this question. As a result guidelines for measurement of blood pressure are not consistent in recommending that patients legs should not be crossed during measurement. OBJECTIVE:To dete...

    journal_title:Blood pressure monitoring

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Peters GL,Binder SK,Campbell NR

    更新日期:1999-04-01 00:00:00

  • Blood pressure cuff comparability study.

    abstract:BACKGROUND:Manufacturer-supplied blood pressure (BP) cuffs are part of the automatic oscillometric BP devices algorithm. MATERIALS AND METHODS:This study assessed the differences in BP values using the Omron HEM 907-XL (Omron) device with two types of cuffs: the Baum cuff (BC) and the supplied Omron cuff (OC). A sampl...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MBP.0000000000000208

    authors: Ostchega Y,Nwankwo T,Zhang G,Chiappa M

    更新日期:2016-12-01 00:00:00

  • Do we undertreat hypertensive smokers? A comparison between smoking and non-smoking hypertensives.

    abstract::The acute effect of smoking is a rise in blood pressure and heart rate. Nevertheless, in several epidemiologic studies, smokers tend to have a slightly lower office blood pressure than non-smokers. We studied the 24 h ambulatory blood pressure consecutively in hypertensive smokers (> or = 10 cigarettes per day, n = 26...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/00126097-200010000-00004

    authors: Bang LE,Buttenschøn L,Kristensen KS,Svendsen TL

    更新日期:2000-10-01 00:00:00

  • Characteristics of conventional blood pressure in studies on the predictive power of ambulatory blood pressure.

    abstract:BACKGROUND:It is commonly believed that the associations of left ventricular mass and cardiovascular morbidity/mortality with blood pressure are stronger for 24-h ambulatory pressure than for conventional clinic or casual pressure. METHODS:The investigation comprised a review of relevant studies, with particular empha...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章,meta分析

    doi:10.1097/00126097-200202000-00006

    authors: Fagard RH,Staessen JA

    更新日期:2002-02-01 00:00:00

  • Nocturnal blood pressure nondipping in obese African-Americans.

    abstract:OBJECTIVES:Nondipping pattern of circadian blood pressure (BP) is associated with increased cardiovascular morbidity and mortality; however, limited data are available among obese African-Americans. We, therefore, aimed to evaluate the pattern of circadian BP variation and to identify clinical conditions associated wit...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/MBP.0b013e328346a871

    authors: Napan S,Kwagyan J,Randall OS,Xu S,Ketete M,Maqbool AR

    更新日期:2011-06-01 00:00:00

  • Ambulatory blood pressure monitoring of chronically dialyzed pediatric patients.

    abstract:BACKGROUND:Background Ambulatory blood pressure monitoring (ABPM) has been shown to be more representative of blood pressure levels in adult patients than are casual measurements of blood pressure. OBJECTIVE:To evaluate, by means of ABPM, the behavior of blood pressure in children with chronic renal failure submitted ...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:

    authors: Koch VH,Furusawa EA,Ignes E,Okay Y,Mion Junior D

    更新日期:1999-10-01 00:00:00

  • Oscillometric sphygmomanometers: a critical appraisal of current technology.

    abstract:AIM:Blood pressure (BP), a key vital sign, monitors general health. Oscillometric devices are increasingly used for measurement, although their accuracy continues to be critically debated. A functional block diagram is used to review the components that affect accuracy. METHODS:A block diagram is presented covering th...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章,评审

    doi:10.1097/MBP.0b013e32835026b0

    authors: Amoore JN

    更新日期:2012-04-01 00:00:00

  • Serum copeptin levels in predicting nondippers in newly diagnosed hypertension.

    abstract:OBJECTIVES:The nondipper pattern in hypertension is associated with worse cardiovascular outcomes. In this study, we hypothesized that high copeptin levels could predict nondippers among hypertensive patients and investigated the associations between copeptin levels and nondipper pattern in newly diagnosed hypertensive...

    journal_title:Blood pressure monitoring

    pub_type: 临床试验,杂志文章

    doi:10.1097/MBP.0000000000000123

    authors: Uzun F,Biyik I,Akturk IF,Yalcin AA,Erturk M,Oner E,Kalkan AK,Yalcin B,Atmaca H

    更新日期:2015-08-01 00:00:00

  • Feasibility of oscillometric aortic pressure and stiffness assessment using the VaSera VS-1500: comparison with a common tonometric method.

    abstract:OBJECTIVES:A number of operator-independent oscillometric devices to measure hemodynamics and arterial stiffness became available recently, but some and in particular VaSera VS-1500 do not provide estimates of aortic pressures and aortic pulse wave velocity (aPWV). The aim of this work was the retrospective application...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/MBP.0000000000000137

    authors: Endes S,Bachler M,Li Y,Mayer C,Hanssen H,Hametner B,Schmidt-Trucksäss A,Wassertheurer S

    更新日期:2015-10-01 00:00:00

  • Validation of the TM-2564G device for in-hospital blood pressure measurement.

    abstract:OBJECTIVE:To perform clinical validation of the TM-2564G device for in-hospital blood pressure measurement according to the British Hypertension Society protocol. METHODS:The tests were carried out on 85 patients aged 19-82 years (41 male patients, mean age 50+/-19 years) with systolic blood pressure 75-219 mmHg and d...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/00126097-200512000-00009

    authors: Kobalava ZD,Kotovskaya YV,Rodionov EV,Moiseev VS

    更新日期:2005-12-01 00:00:00

  • An extended validation of the ScottCare 320 ambulatory blood pressure monitor: recommendations for clinical application.

    abstract:OBJECTIVES:The purpose of this study was to validate the ScottCare 320 ambulatory blood pressure monitor (ABPM) using both group-level and individual-level validation procedures. The group-level validation followed a modified protocol of the European Hypertension Society's validation protocol. The individual-level vali...

    journal_title:Blood pressure monitoring

    pub_type: 临床试验,杂志文章

    doi:10.1097/MBP.0b013e32835f4fc7

    authors: Zawadzki MJ,Vandekar L,Smyth JM,Haas D,Gerin W

    更新日期:2013-06-01 00:00:00

  • Validation of the A&D wrist-cuff UB-511 (UB-512) device for self-measurement of blood pressure.

    abstract:OBJECTIVES:To determine the accuracy of the A&D UB-511 (UB-512) oscillometric wrist-cuff device for self-measurement of blood pressure, the only difference between the two devices being the size of storage memory. METHODS:Device evaluation was performed according to the modified British Hypertension Society protocol r...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.mbp.0000217995.12215.f2

    authors: Angeli F,Sardone M,Angeli E,Repaci S,Gattobigio R,Verdecchia P

    更新日期:2006-12-01 00:00:00

  • Conventional and ambulatory measurements of blood pressure in old patients with isolated systolic hypertension: baseline observations in the Syst-Eur trial.

    abstract::OBJECTIVES: To compare clinic and am measurements of blood pressure in old patients with isolated systolic hypertension and their reproducibilities. PATIENTS: In total 610 patients aged >/= 60 years with isolated systolic hypertension detected by clinic measurement were monitored during the placebo run-in phase of the...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:

    authors: Emelianov D,Thijs L,Staessen JA,Celis H,Clement D,Davidson C,Gasowski J,Gil-Extremera B,Fogari R,Jääskivi M,Lehtonen A,Nedogoda S,O'Brien E,Palatini P,Parati G,Salvetti A,Vanhanen H,Webster J,Fagard R

    更新日期:1998-06-01 00:00:00

  • Prognostic significance of self-measurements of blood pressure.

    abstract:BACKGROUND:Self-measurements of blood pressure may offer some advantage in diagnostic and therapeutic evaluation and in management of patients. However, the most important limitation of self-measurement is that there are limited data available about the prognostic value of this information. RESULTS:Authors of several ...

    journal_title:Blood pressure monitoring

    pub_type: 共识发展会议,杂志文章,评审

    doi:

    authors: Imai Y,Poncelet P,DeBuyzere M,Padfield PL,Van Montfrans GA

    更新日期:2000-04-01 00:00:00

  • Acute effects of moderate-intensity and high-intensity exercise on hemodynamic and autonomic reactivity to the cold pressor test in young adults with excess body weight.

    abstract:OBJECTIVE:To investigate the effects of a single session of moderate-intensity and high-intensity interval exercise in cardiovascular reactivity to the cold pressor test in young adults with excess body weight. METHODS:Twenty-two subjects with excess body weight (23 ± 2 years; 30.0 ± 3.4 kg·m) performed three sessions...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/MBP.0000000000000422

    authors: Meireles K,Peçanha T,Dias ARL,Souza KA,Araújo JA,Silva JS,Rezende DAN,Santos RJ,Cambri LT,Arsa G

    更新日期:2020-04-01 00:00:00

  • The effect of crossing legs on blood pressure.

    abstract:OBJECTIVE:To determine whether crossing of the legs at the knee or at the ankles during blood pressure measurement in sitting position has an effect on blood pressure. METHODS:One hundred and eleven patients, 60 women, mean age 52+/-17 years (19-80): 49 chronically treated hypertensives, 28 treated diabetics and 34 no...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/MBP.0b013e3280b083a7

    authors: Adiyaman A,Tosun N,Elving LD,Deinum J,Lenders JW,Thien T

    更新日期:2007-06-01 00:00:00

  • Prevalence and determinants of masked hypertension among obese individuals at the Yaoundé Central Hospital: a cross-sectional study in sub-Saharan Africa.

    abstract:OBJECTIVES:The aim of this study was to investigate the prevalence and associated factors of masked hypertension in obese patients in Yaounde. METHODS:We carried out a cross-sectional study from January to September 2017 at the National Obesity Center of the Yaounde Central Hospital. Masked hypertension was defined wh...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/MBP.0000000000000457

    authors: Hamadou B,Amougou SN,Tchuendem Y,Nganou-Gnindjio CN,Mfeukeu-Kuate L,Foka AJ,Tankeu AT,Jingi AM,Menanga AP,Kingue S

    更新日期:2020-08-01 00:00:00

  • Validation protocols for blood pressure-measuring devices: status quo and development needs.

    abstract::Hypertension is a major risk factor for cardiovascular morbidity and mortality. Therefore, blood pressure self-measuring devices have emerged as valuable tools in patient care and the accuracy of these instruments is of fundamental importance. For this reason, several validation procedures for assessing the efficacy o...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章,评审

    doi:10.1097/MBP.0000000000000150

    authors: Beime B,Deutsch C,Gomez T,Zwingers T,Mengden T,Bramlage P

    更新日期:2016-02-01 00:00:00

  • Accuracy of the WatchBP O3 device for ambulatory blood pressure monitoring according to the new criteria of the ISO81060-2 2018 protocol.

    abstract:OBJECTIVE:The aim of the study was to determine the accuracy of the Microlife WatchBP O3 monitor for ambulatory blood pressure (BP) measurement according to the new ISO81060-2 2018 protocol. METHODS:The WatchBP O3 was first tested in 97 subjects from the general population (mean age, 71.3 years; 48 men) using four cuf...

    journal_title:Blood pressure monitoring

    pub_type: 杂志文章

    doi:10.1097/MBP.0000000000000459

    authors: Fania C,Lazzaretto I,Fontana U,Palatini P

    更新日期:2020-10-01 00:00:00