Reductions in muscle quality and quantity in chronic inflammatory demyelinating polyneuropathy patients assessed by magnetic resonance imaging.

abstract：:The possibility has been raised that in familial periodic paralysis, the relatively large depolarization of the muscle fiber membrane seen during periods of paralysis might be attributable to a reduction in activity of the electrogenic Na(+)-K+ pump. The theoretical analysis presented here shows that although such hyp...

journal_title：Muscle & nerve

authors： Martin AR,Levinson SR

更新日期：1985-06-01 00:00:00

abstract：:Injection of low-dose arachidonic acid into the rat femoral artery occludes the vasa nervorum of the tibial nerve and produces focal and generalized ischemia with transient effects on nerve conduction. Across a severely ischemic segment of the proximal tibial nerve there is a marked fall in amplitude of the compound m...

journal_title：Muscle & nerve

authors： Parry GJ,Linn DJ

更新日期：1986-05-01 00:00:00

abstract：:We previously reviewed the presentation, initial clinical course, and electrodiagnostic features of children with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). We now report the long-term follow-up of 12 children with idiopathic CIDP, and compare these to 62 adults with idiopathic CIDP. Children of...

journal_title：Muscle & nerve

authors： Simmons Z,Wald JJ,Albers JW

更新日期：1997-12-01 00:00:00

abstract：INTRODUCTION:We tested for the presence of erythropoietin receptor (Epo-R) in human skeletal muscle and alterations in gene expression after prolonged use of an erythropoiesis-stimulating agent (ESA). METHODS:Nine healthy men were treated with ESA for 10 weeks (darbepoietin alfa). Muscle biopsies were collected before...

journal_title：Muscle & nerve

authors： Christensen B,Nellemann B,Thorsen K,Nielsen MM,Pedersen SB,Ornstrup MJ,JØrgensen JO,Jessen N

更新日期：2015-04-01 00:00:00

abstract：INTRODUCTION:Duchenne muscular dystrophy (DMD) is characterized by absence of the subsarcolemmal protein dystrophin, present in skeletal muscles and cardiomyocytes. We hypothesized that progressive respiratory and left ventricular (LV) insufficiencies in DMD could be parallel and interrelated phenomena. METHODS:We con...

journal_title：Muscle & nerve

authors： Khokhar A,Nair A,Midya V,Kumar A,Sinharoy A,Ahmad TA,Abu-Hasan M,Mondal P

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Limited data exist regarding myopathies with early or prominent dysphagia. METHODS:A retrospective study was performed (January 2003 to August 2019) to identify myopathy patients in whom dysphagia was the initial symptom or was disproportionately severe compared with limb weakness. RESULTS:Thirty-two patie...

journal_title：Muscle & nerve

authors： Triplett JD,Pinto MV,Hosfield EA,Milone M,Liewluck T

更新日期：2020-09-01 00:00:00

abstract：:The neuromuscular junction (NMJ) is a complex structure that serves to efficiently communicate the electrical impulse from the motor neuron to the skeletal muscle to signal contraction. Over the last 200 years, technological advances in microscopy allowed visualization of the existence of a gap between the motor neuro...

journal_title：Muscle & nerve

authors： Hughes BW,Kusner LL,Kaminski HJ

更新日期：2006-04-01 00:00:00

abstract：:The dystrophin protein complex (DPC), composed of at least 10 proteins that associate with dystrophin, is critical for the maintenance of normal muscle fiber structure and physiology. In this study, we used immunohistochemistry and confocal microscopy to examine the relative abundance and distribution of several of th...

journal_title：Muscle & nerve

authors： Draviam R,Billington L,Senchak A,Hoffman EP,Watkins SC

更新日期：2001-02-01 00:00:00

abstract：:The sternocleidomastoid muscle (SCM) is one of the major muscles involved in producing abnormal head position in cervical dystonia patients. This study tested whether doxorubicin chemomyectomy, direct injection of doxorubicin into the SCM to permanently remove muscle fibers, has the potential to be a nonsurgical, perm...

journal_title：Muscle & nerve

authors： McLoon LK,Falkenberg JH,Dykstra D,Iaizzo PA

更新日期：1998-11-01 00:00:00

abstract：:Ischemia-reperfusion injury is implicated in the failure of free flap and replant surgeries and is associated with the pathogenesis of a wide variety of clinical diseases including stroke, myocardial infarction, spinal injury, and compartment syndromes. We used a skeletal muscle flap model to test if the induction of ...

journal_title：Muscle & nerve

authors： Lille S,Su CY,Schoeller T,Suchy H,Lyons S,Russell RC,Neumeister M,Lai CC

更新日期：1999-03-01 00:00:00

abstract：:Mutations of the valosin-containing protein gene (VCP) are responsible for autosomal-dominant hereditary inclusion-body myopathy associated with frontotemporal dementia and Paget's disease of bone. We identified the p.R155C missense mutation in the VCP gene segregating in an Italian family with three affected siblings...

journal_title：Muscle & nerve

authors： Gidaro T,Modoni A,Sabatelli M,Tasca G,Broccolini A,Mirabella M

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Information related to the long-term follow-up of neuropathy in patients with familial amyloid polyneuropathy after liver transplantation is still scarce. METHODS:We describe the neuropathic features of 3 patients with the transthyretin Val30Met mutation. Each patient underwent liver transplantation at an...

journal_title：Muscle & nerve

authors： Koike H,Hashimoto R,Tomita M,Kawagashira Y,Iijima M,Nakamura T,Watanabe H,Kamei H,Kiuchi T,Sobue G

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:This study sought to estimate the global prevalence of transthyretin familial amyloid polyneuropathy (ATTR-FAP). METHODS:Prevalence estimates and information supporting prevalence calculations was extracted from records yielded by reference-database searches (2005-2016), conference proceedings, and nonpee...

journal_title：Muscle & nerve

authors： Schmidt HH,Waddington-Cruz M,Botteman MF,Carter JA,Chopra AS,Hopps M,Stewart M,Fallet S,Amass L

更新日期：2018-05-01 00:00:00

abstract：:Human normal (RCMH) and Duchenne muscular dystrophy (RCDMD) cell lines, as well as newly developed normal and dystrophic murine cell lines, were used for the study of both changes in inositol 1,4,5-trisphosphate (IP3) mass and IP3 binding to receptors. Basal levels of IP3 were increased two- to threefold in dystrophic...

journal_title：Muscle & nerve

authors： Liberona JL,Powell JA,Shenoi S,Petherbridge L,Caviedes R,Jaimovich E

更新日期：1998-07-01 00:00:00

abstract：:Motor involvement in acute herpes zoster is considered rare, but its incidence is unknown. In a sample of 40 patients with acute herpes zoster of varying severity, an abnormal electromyogram (EMG) (fibrillation, positive waves, high-frequency discharges) was found in 21 (53%), suggesting extension of inflammation to t...

journal_title：Muscle & nerve

authors： Haanpää M,Häkkinen V,Nurmikko T

更新日期：1997-11-01 00:00:00

abstract：:We studied 137 ulnar nerves and abductor digiti minimi (ADM) muscles in 70 patients with amyotrophic lateral sclerosis (ALS), and correlated the results with ADM strength graded on the Medical Research Council (MRC) scale, to address the potential value of a standardized neurophysiological assessment of this nerve-mus...

journal_title：Muscle & nerve

authors： de Carvalho M,Swash M

更新日期：2000-03-01 00:00:00

abstract：:Motor unit action potentials (MUAPs) evoked by repetitive, low-intensity transcranial magnetic stimulation can be modeled as a Poisson process. A mathematical consequence of such a model is that the ratio of the variance to the mean of the amplitudes of motor evoked potentials (MEPs) should provide an estimate of the ...

journal_title：Muscle & nerve

authors： Kaelin-Lang A,Conforto AB,Z'Graggen W,Hess CW

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:Cerebral palsy (CP) is associated with reduced muscle volumes, but previous studies have reported deficits in only a small number of muscles. The extent of volume deficits across lower limb muscles is not known. This study presents an imaging-based assessment of muscle volume and length deficits in 35 lowe...

journal_title：Muscle & nerve

authors： Handsfield GG,Meyer CH,Abel MF,Blemker SS

更新日期：2016-06-01 00:00:00

abstract：:Exercise intolerance and undue fatigue are common complaints in patients with Charcot-Marie-Tooth (CMT) disease. Reduced physical ability is due directly to the disease, but it is also due to physical deconditioning. The aim of this study was to test whether 24 weeks of interval-training exercise (ITE) cycling can sig...

journal_title：Muscle & nerve

authors： El Mhandi L,Millet GY,Calmels P,Richard A,Oullion R,Gautheron V,Féasson L

更新日期：2008-05-01 00:00:00

abstract：:Diagnosis of multifocal motor neuropathy (MMN), a syndrome characterized by progressive asymmetric weakness with intact sensation, is important because the disorder often responds to treatment. Multifocal partial motor conduction block (PMCB) has been emphasized as a cardinal feature in the diagnosis of this syndrome,...

journal_title：Muscle & nerve

authors： Chaudhry V,Corse AM,Cornblath DR,Kuncl RW,Freimer ML,Griffin JW

更新日期：1994-02-01 00:00:00

abstract：:We describe two cases of neuralgic amyotrophy with electrophysiological evidence of conduction block across the lower trunk of the brachial plexus. Low-output impedance stimulation of the cervical spinal roots in combination with collision was used to accurately demonstrate the conduction block. Complete electrophysio...

journal_title：Muscle & nerve

authors： Watson BV,Nicolle MW,Brown JD

更新日期：2001-04-01 00:00:00

abstract：:Muscle sodium-channel disorders cover a spectrum of rare myotonic diseases. In a German family with 17 affected individuals in four generations, we identified a heterozygous missense mutation in exon 24 A1481D (c.4442 C>A) of the voltage-gated sodium channel gene (SCN4A) alpha subunit. Phenotypes of 12 family members ...

journal_title：Muscle & nerve

authors： Schoser BG,Schröder JM,Grimm T,Sternberg D,Kress W

更新日期：2007-05-01 00:00:00

abstract：:A patient in perfect health prior to electrical shock developed an ALS-like syndrome after the shock. Onset of the disease occurred in the limb through which the shock entered, and subsequently followed a course well-described in previous case reports. Possible mechanisms of disease are discussed. ...

journal_title：Muscle & nerve

authors： Sirdofsky MD,Hawley RJ,Manz H

更新日期：1991-10-01 00:00:00

abstract：:There were 31 Duchenne patients placed on overnight mouth intermittent positive pressure ventilation for severe respiratory insufficiency at the average age of 19.9 years. Most patients had vital capacities less than 200 cc at their last evaluations. Of these, 23 patients are alive at the average age of 27 years and l...

journal_title：Muscle & nerve

authors： Bach JR,O'Brien J,Krotenberg R,Alba AS

更新日期：1987-02-01 00:00:00

abstract：INTRODUCTION:When treating ocular myasthenia gravis (MG), the risk/benefit profile of corticosteroids is unclear, and acetylcholinesterase inhibitors are not very effective. We examined the efficacy of topical naphazoline in the treatment of myasthenic blepharoptosis. METHODS:Sixty MG patients with blepharoptosis (32 ...

journal_title：Muscle & nerve

authors： Nagane Y,Utsugisawa K,Suzuki S,Masuda M,Shimizu Y,Utsumi H,Uchiyama S,Suzuki N

更新日期：2011-07-01 00:00:00

abstract：:The clinical efficacy of functional electrical stimulation (FES) is limited by the rapid onset of fatigue. Functional electrical stimulation applications typically stimulate skeletal muscles with constant-frequency trains (CFTs). Our laboratory has identified trains that we call doublet-frequency trains (DFTs) and tha...

journal_title：Muscle & nerve

authors： Scott WB,Lee SC,Johnston TE,Binder-Macleod SA

更新日期：2005-05-01 00:00:00

abstract：:The present study was conducted to determine the effects of acute overload exercise on mitochondrial DNA and the structure of skeletal muscles. Rats were forced to run for 20 min until reaching complete exhaustion. We detected the large-scale deletion (7052 bp) of mitochondrial DNA by the nested polymerase chain react...

journal_title：Muscle & nerve

authors： Sakai Y,Iwamura Y,Hayashi J,Yamamoto N,Ohkoshi N,Nagata H

更新日期：1999-02-01 00:00:00

abstract：:An appreciation of the comparative functions of the corticospinal tract is of direct relevance to the understanding of how results from animal models can advance knowledge of the human motor system and its disorders. Two critical functions of the corticospinal tract are discussed: first, the role of descending project...

journal_title：Muscle & nerve

authors： Lemon RN,Griffiths J

更新日期：2005-09-01 00:00:00

abstract：INTRODUCTION:Glucocorticosteroids (GC) are effective in slowing weakness in boys with Duchenne muscular dystrophy (DMD). METHODS:This is a multisite, 1-year, open-label trial of twice-weekly prednisolone (5 mg/kg/dose) in infants/young boys (0.4-2.4 years) with DMD. We compared changes in Bayley III Scales of Infant D...

journal_title：Muscle & nerve

authors： Connolly AM,Zaidman CM,Golumbek PT,Cradock MM,Flanigan KM,Kuntz NL,Finkel RS,McDonald CM,Iannaccone ST,Anand P,Siener CA,Florence JM,Lowes LP,Alfano LN,Johnson LB,Nicorici A,Nelson LL,Mendell JR,MDA DMD Clinical Resea

更新日期：2019-06-01 00:00:00

abstract：:We report two female patients with a history of alcohol abuse presenting with proximal painful muscle weakness following aversion therapy with emetine hydrochloride. Muscle biopsy of Case 1 showed a reversible floccular-shaped loss of myosin ATPase and dehydrogenase, an accumulation of PAS positive material, and a nor...

journal_title：Muscle & nerve

authors： Sugie H,Russin R,Verity MA

更新日期：1984-01-01 00:00:00