Abstract：
:Muscarinic receptors can be pharmacologically classified into 3 types at the present time, however, five genes for the receptor have been identified. The muscarinic receptor types have unique antagonist selectivity, distribution and are linked to specific second messenger systems. The interaction between the muscarinic receptor types and G proteins may depend on the systems in which the receptors are integrated. Expression of the cloned gene in mammalian cells will be useful in delineating the relationships between the pharmacological types of muscarinic receptors and their genes and studying the interactions between the receptor, G proteins, and second messenger coupling.
journal_name
Life Scijournal_title
Life sciencesauthors
Mei L,Roeske WR,Yamamura HIdoi
10.1016/0024-3205(89)90537-7subject
Has Abstractpub_date
1989-01-01 00:00:00pages
1831-51issue
20eissn
0024-3205issn
1879-0631pii
0024-3205(89)90537-7journal_volume
45pub_type
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