Abstract:
AIMS:To elucidate the intramuscular distribution and branching patterns of the abducens nerve in the lateral rectus (LR) muscle so as to provide anatomical confirmation of the presence of compartmentalization, including for use in clinical applications such as botulinum toxin injections. METHODS:Thirty whole-mount human cadaver specimens were dissected and then Sihler's stain was applied. The basic dimensions of the LR and its intramuscular nerve distribution were investigated. The distances from the muscle insertion to the point at which the abducens nerve enters the LR and to the terminal nerve plexus were also measured. RESULTS:The LR was 46.0 mm long. The abducens nerve enters the muscle on the posterior one-third of the LR and then typically divides into a few branches (average of 1.8). This supports a segregated abducens nerve selectively innervating compartments of the LR. The intramuscular nerve distribution showed a Y-shaped ramification with root-like arborization. The intramuscular nerve course finished around the middle of the LR (24.8 mm posterior to the insertion point) to form the terminal nerve plexus. This region should be considered the optimal target site for botulinum toxin injections. We have also identified the presence of an overlapping zone and communicating nerve branches between the neighboring LR compartments. CONCLUSION:Sihler's staining is a useful technique for visualizing the entire nerve network of the LR. Improving the knowledge of the nerve distribution patterns is important not only for researchers but also clinicians to understand the functions of the LR and the diverse pathophysiology of strabismus.
journal_name
Curr Eye Resjournal_title
Current eye researchauthors
Shin HJ,Lee SH,Shin KJ,Koh KS,Song WCdoi
10.1080/02713683.2018.1438631subject
Has Abstractpub_date
2018-06-01 00:00:00pages
689-695issue
6eissn
0271-3683issn
1460-2202journal_volume
43pub_type
杂志文章abstract::Previous attempts to prepare monoclonal antibodies (MAbs) against S-antigen, a photoreceptor cell protein involved in the visual process and a potent autoantigen for the induction of experimental autoimmune uveitis (EAU), have yielded MAbs which define only carboxyl terminal epitopes. In this study we devised alternat...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713689008999622
更新日期:1990-04-01 00:00:00
abstract:PURPOSE:To evaluate the immediate effect of 3% diquafosol ophthalmic solution on tear MUC5AC concentration, periodic acid-Schiff (PAS)-positive goblet cells, and tear film stability in normal and keratoconjunctivitis sicca (KCS) rat models. METHODS:Rats were divided into normal and KCS groups. 3% of diquafosol solutio...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713683.2016.1233986
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abstract::Lipid synthesis was investigated in bovine lens in organ culture for 9 hours using 14C acetate as a precursor. The greatest incorporation occurred in phospholipid fraction with phosphatidyl choline being the major phospholipid labeled. Considerable activity was incorporated in the free fatty acid fraction, cholesterol...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713688709034889
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abstract::Calmodulin has been shown to perform several important functions in the lens including regulation of the plasma membrane Ca(2+)-ATPase. This study investigated the effects of a variety of different CaM antagonists on rat lens membrane potential, membrane resistance, intracellular Na+ and Ca2+ content and transparency,...
journal_title:Current eye research
pub_type: 杂志文章
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713688109019985
更新日期:1981-01-01 00:00:00
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journal_title:Current eye research
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713688809033207
更新日期:1988-08-01 00:00:00
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更新日期:1992-01-01 00:00:00
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journal_title:Current eye research
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doi:10.3109/02713689209001798
更新日期:1992-05-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713689808951219
更新日期:1998-04-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713689308995765
更新日期:1993-08-01 00:00:00
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journal_title:Current eye research
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713688709020074
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journal_title:Current eye research
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2020-09-11 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
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更新日期:2002-06-01 00:00:00
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journal_title:Current eye research
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1987-01-01 00:00:00
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更新日期:2002-12-01 00:00:00
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journal_title:Current eye research
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更新日期:1997-03-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713680490889465
更新日期:2004-12-01 00:00:00
abstract:PURPOSE:Phagocytosis of rod outer segments (ROS) is an important function of retinal pigment epithelial (RPE) cells. Since the details of the process are not fully known, we studied effects of cytokines produced by RPE and photoreceptor cells on phagocytosis of ROS by rat RPE cells. METHODS:RPE cells were isolated and...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713689609000760
更新日期:1996-05-01 00:00:00
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journal_title:Current eye research
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更新日期:2015-01-01 00:00:00