ZBTB17 loss-of-function mutation contributes to familial dilated cardiomyopathy.

abstract：:A cardiac angiotensin II-generating system is thought to be involved in cardiac fibrosis. Both angiotensin-converting enzyme (ACE) and human chymase can convert angiotensin I to angiotensin II. However, the relative contributions of these two enzymatic pathways to angiotensin II generation in vivo remain to be clarifi...

journal_title：Heart and vessels

authors： Ohmichi N,Iwai N,Shimoike H,Izumi M,Watarida S,Mori A,Nakamura Y,Kinoshita M

更新日期：1997-01-01 00:00:00

abstract：:Soluble urokinase-type plasminogen activator receptor (suPAR) is a membrane-binding protein that is released into the blood stream by immune activation. Recent reports suggest that circulating suPAR levels are associated with adverse cardiovascular outcomes. Exercise tolerance is an independent predictor of prognosis ...

journal_title：Heart and vessels

authors： Ishikawa H,Izumiya Y,Shibata A,Ichikawa Y,Yamaguchi T,Yamaguchi Y,Kitada R,Iwata S,Ehara S,Tomita S,Hanatani A,Yoshiyama M

更新日期：2020-05-01 00:00:00

abstract：:It has been shown that green tea catechins (GTC) suppress proliferation of vascular smooth muscle cells (VSMCs) and that epigallocatechin-3-gallate (EGCG), which is a major constituent of GTC, selectively inhibits the platelet-derived growth factor-BB (PDGF-BB)-induced intracellular signaling transduction pathway. Vas...

journal_title：Heart and vessels

authors： Kim DW,Park YS,Kim YG,Piao H,Kwon JS,Hwang KK,Youn TJ,Park JB,Yun YP,Sachinidis A,Kim CH,Cho MC,Ahn HY

更新日期：2004-09-01 00:00:00

abstract：:The overall transfer function of a photoplethysmograph (PPG) converting changes in intravascular volume to changes in recorder pen deflection was investigated. The specifications of the apparatus working as a red cell densitometer were assessed in vitro, and it was found that PPG output is a logarithmic function of re...

journal_title：Heart and vessels

authors： Jespersen LT,Pedersen OL

更新日期：1986-01-01 00:00:00

abstract：:In the original publication of the article, under the results section, the following sentence. ...

journal_title：Heart and vessels

authors： Watanabe T,Kanzaki Y,Yamauchi Y,Ito T,Nishida Y,Yamamura K,Komori T,Sohmiya K,Hoshiga M

更新日期：2020-05-01 00:00:00

abstract：:Blood traces tortuous paths of flow through the heart. We postulate that momentum changes associated with direction changes optimize dynamic coupling between ventricular and atrial function, particularly on exercise. Traces of pulsed Doppler mitral flow and M-mode long-axis mitral ring movement were recorded before an...

journal_title：Heart and vessels

authors： Kilner PJ,Henein MY,Gibson DG

更新日期：1997-01-01 00:00:00

abstract：:Normoxic isolated rat hearts were perfused for 30 or 60 min with Krebs-Henseleit bicarbonate buffer (KHB) (in which the Pi concentration was adjusted to 0, 1.2, 2.4, or 10 mM) in both the presence and the absence of glucose as exogenous substrate. Functional performance and coronary flow were monitored throughout the ...

journal_title：Heart and vessels

authors： Humphrey SM,Armiger LC,Holliss DG,Buckman JE

更新日期：1988-01-01 00:00:00

abstract：:A transient left ventricular apical ballooning (so-called "ampulla" or "Takotsubo-shaped" cardiomyopathy) with type I CD36 deficiency is described in a 71-year-old woman. The patient was referred because of chest pain and worsening of dyspnea. Electrocardiogram showed T-wave inversions on the precordal leads, and acut...

journal_title：Heart and vessels

authors： Kushiro T,Saito F,Kusama J,Takahashi H,Imazeki T,Tani S,Kikuchi S,Imai S,Matsudaira K,Watanabe I,Hino T,Sato Y,Nakayama T,Nagao K,Kanmatsuse K

更新日期：2005-05-01 00:00:00

abstract：:The modulation of L-type Ca2+ currents (I(Ca,L)) by the basal activities of G proteins was studied in adult guinea pig ventricular myocytes by whole-cell patch-clamp techniques. With intrapipette guanosine triphosphate (GTP) (100 microM), a specific inhibition of G1 proteins by pertussis toxin (PTX) produced an increa...

journal_title：Heart and vessels

authors： Makita T,Horie M,Xie LH,Okada Y,Sasayama S

更新日期：2000-01-01 00:00:00

abstract：:Since the amount of contrast media during percutaneous coronary intervention (PCI) is closely related to the exacerbation of renal function, it should be important to reduce the dose of contrast media during PCI. The purpose of this retrospective study was to evaluate the association of less-contrast media with clinic...

journal_title：Heart and vessels

authors： Mukai Y,Sakakura K,Yamamoto K,Taniguchi Y,Tsukui T,Seguchi M,Wada H,Momomura SI,Fujita H

更新日期：2020-02-01 00:00:00

abstract：:Distal anastomosis technique affects graft patency and long-term outcomes in coronary artery bypass grafting, however, there is no standard for the appropriate length of distal anastomosis. The purpose of this study is to evaluate whether longer distal anastomosis provides higher quality of distal anastomosis and bett...

journal_title：Heart and vessels

authors： Tsukui H,Shinke M,Park YK,Yamazaki K

更新日期：2017-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is a complex disease with multiple inter-relating causes culminating in rapid atrial activation and atrial structural remodeling. The contribution of endoplasmic reticulum and mitochondria stress to AF has been highlighted. As the class III antiarrhythmic agent, ibutilide are widely used to AF...

journal_title：Heart and vessels

authors： Wang Y,Wang YL,Huang X,Yang Y,Zhao YJ,Wei CX,Zhao M

更新日期：2017-02-01 00:00:00

abstract：:This study was designed to test the ability of adenovirus-delivered vascular endothelial growth factor (Ad-VEGF) to stimulate angiogenesis and arteriogenesis in the rabbit hindlimb following the induction of ischemia and to evaluate the functional changes in the collateral circulation. Ten days after the surgical indu...

journal_title：Heart and vessels

authors： Hershey JC,Baskin EP,Corcoran HA,Bett A,Dougherty NM,Gilberto DB,Mao X,Thomas KA,Cook JJ

更新日期：2003-07-01 00:00:00

abstract：:Downregulation of glucose and fatty acid oxidation occurs in heart failure (HF). Trimetazidine reduces fatty acid oxidation and increases glucose oxidation. In this single-blind study, trimetazidine, 20 mg three times per day (n = 51) or placebo (n = 36) was added to treatment of 87 HF patients receiving optimal HF th...

journal_title：Heart and vessels

authors： Gunes Y,Guntekin U,Tuncer M,Sahin M

更新日期：2009-07-01 00:00:00

abstract：:Abnormal P-wave characteristics were reportedly associated with left ventricular interstitial fibrosis as defined by cardiac magnetic resonance images. The objective of this study is to investigate the utility of P-wave characteristics to predict atrial fibrillation (AF) recurrence and the recovery of left ventricular...

journal_title：Heart and vessels

authors： Doi A,Takagi M,Katayama H,Yoshiyama T,Hayashi Y,Tatsumi H,Yoshiyama M

更新日期：2018-11-01 00:00:00

abstract：:Left ventricular (LV) remodeling in systemic arterial hypertension causes electrical conduction delay and impairs synchronous contraction, which may contribute to the development of heart failure. This study aimed to assess the change of LV mechanics in hypertension by layer-specific dyssynchrony. One hundred and twen...

journal_title：Heart and vessels

authors： Kim SA,Kim MN,Shim WJ,Park SM

更新日期：2016-04-01 00:00:00

abstract：:Very late stent thrombosis (VLST) is a serious complication after percutaneous coronary intervention. However, the best therapy for VLST with late-acquired incomplete stent apposition and incomplete neointimal coverage remains unknown. In these cases, neointimal coverage was nearly complete and no late-acquired malapp...

journal_title：Heart and vessels

authors： Kakefuda Y,Sato A,Watabe H,Aihara H,Nishina H,Noguchi Y,Hoshi T,Aonuma K

更新日期：2016-07-01 00:00:00

abstract：:We investigated the signaling mechanism of stretch-induced cell remodeling in human umbilical vein endothelial cells (HUVECs). Freshly dissociated HUVECs were cultured on an elastic silicon membrane and subjected to uniaxial cyclic stretch (20% in length, 1 Hz). The cells started to change their morphology as early as...

journal_title：Heart and vessels

authors： Sokabe M,Naruse K,Sai S,Yamada T,Kawakami K,Inoue M,Murase K,Miyazu M

更新日期：1997-01-01 00:00:00

abstract：:Vascular calcification is an ectopic calcification that commonly occurs in atherosclerosis. Because taurine was previously shown to protect against cardiovascular diseases, the effect of taurine on vascular calcification was evaluated in calcified vascular smooth muscle cells (VSMCs) of rat in vitro in the present stu...

journal_title：Heart and vessels

authors： Li J,Zhang B,Huang Z,Wang S,Tang C,Du J

更新日期：2004-05-01 00:00:00

abstract：:Complex congenital heart diseases with abnormal formation of the aorticopulmonary septum are also associated with defective large artery elastogenesis. In the current study, we tested the hypothesis that carotid artery elastic function was impaired in patients with tetralogy of Fallot (ToF). The study included 45 Fall...

journal_title：Heart and vessels

authors： László A,Pintér A,Horváth T,Kádár K,Temesvári A,Kollai M,Studinger P

更新日期：2011-09-01 00:00:00

abstract：:We investigated the incidence of post-intubation hypotension (PIH) in hemodynamically stable patients with STEMI requiring rapid sequences intubation (RSI) and medicated with ketamine or midazolam as induction agent. STEMI patients admitted between 1st January 2009 and 1st January 2017 who did not receive any type of ...

journal_title：Heart and vessels

authors： Zuin M,Rigatelli G,Dell'Avvocata F,Faggian G,Conte L,Giatti S,Michielan F,Roncon L

更新日期：2018-03-01 00:00:00

abstract：:The use of cine-computed tomography scanning is described in evaluating cardiac function in a patient with a bileaflet mitral valve prosthesis (St. Jude medical valve) and in a second patient with both mitral and aortic bileaflet prostheses. Both biventricular and prosthesis function were assessed successfully. ...

journal_title：Heart and vessels

authors： Wachspress JD,Untereker WJ,Kraushaar BT

更新日期：1987-01-01 00:00:00

abstract：:This study aimed to search genes altered in expression after long-term treatment with the angiotensin II type 1 receptor (AT1) antagonist, CV-11974, in volume-overloaded hearts. Arteriovenous shunt was made between the common carotid artery and jugular vein in Japanese White rabbits. Shunt-operated rabbits were random...

journal_title：Heart and vessels

authors： Itoh M,Takeishi Y,Nakada S,Miyamoto T,Tsunoda Y,Takahashi H,Kubota I,Tomoike H

更新日期：2002-11-01 00:00:00

abstract：:The relations of the light chains of myosins of the atria, ventricles, and atrioventricular conducting tissue (specialized myocardial tissue) and the distribution of the light chains of myosin in different regions of the atrioventricular conducting tissue in bovine heart were examined. Two-dimensional gel electrophore...

journal_title：Heart and vessels

authors： Tamura Y,Orino S,Saijyo Y,Nishimoto T,Nagase N,Mori H

更新日期：1986-01-01 00:00:00

abstract：:Activities of daily living (ADL) are maintained in patients with mild cognitive impairment (MCI), but, in patients with cardiovascular disease, ADL may have already declined. MCI combined with cardiac disease may accentuate the decline of ADL in these patients. Because the relationship between MCI and ADL in patients ...

journal_title：Heart and vessels

authors： Ishihara K,Izawa KP,Kitamura M,Shimogai T,Kanejima Y,Morisawa T,Shimizu I

更新日期：2019-12-01 00:00:00

abstract：:Vascular smooth muscle cell (VSMC) differentiation and phenotypic modulation are characterized by changes in gene expression for smooth muscle (SM) marker contractile proteins such as SM alpha-actin and SM22alpha. Hyperplasia suppressor gene (HSG) is a potent VSMC proliferation-inhibiting factor; however, it is not kn...

journal_title：Heart and vessels

authors： Jiang GJ,Han M,Zheng B,Wen JK

更新日期：2006-09-01 00:00:00

abstract：:Atrial tachyarrhythmias often originate from the superior vena cava (SVC), and right superior (RSPV) and inferior pulmonary veins (RIPV). However, a precise differentiation of those origins is challenging using the standard 12-lead electrocardiogram (ECG) P-wave morphology due to the anatomical proximity. The recently...

journal_title：Heart and vessels

authors： Hisazaki K,Miyazaki S,Hasegawa K,Kaseno K,Amaya N,Shiomi Y,Tama N,Ikeda H,Fukuoka Y,Morishita T,Ishida K,Uzui H,Tada H

更新日期：2020-02-01 00:00:00

abstract：:The vascular endothelial growth factor (VEGF) family of peptides and caveolins (CAVs) are reported to contribute, in early graft failure in patients, a coronary artery bypass grafting (CABG). To investigate the possible association of ultimate luminal occlusion to VEGFs and CAVs expression, a functional analysis (base...

journal_title：Heart and vessels

authors： Podemska-Jedrzejczak Z,Malinska A,Sujka-Kordowska P,Nowicki M,Puslecki M,Jemielity M,Perek B

更新日期：2018-09-01 00:00:00

abstract：:An unusual case of total occlusion of aorta just distal to the left subclavian artery, bicuspid aortic valve, and occluded left external iliac artery in a 21-year-old man who was admitted with headache and severe hypertension is presented. We wish to report this case because so far there have been none reported with s...

journal_title：Heart and vessels

authors： Tanindi A,Tavil Y,Mutluay R,Taktak H,Cengel A

更新日期：2007-03-01 00:00:00

abstract：:Right atrial pressure (RAP), a representative parameter of right heart failure, is very important for prognostic evaluation and risk assessment in pulmonary hypertension. However, its measurement requires invasive cardiac catheterization. In this study, we determined the most accurate echocardiographic surrogate of ca...

journal_title：Heart and vessels

authors： Watanabe R,Amano H,Saito F,Toyoda S,Sakuma M,Abe S,Nakajima T,Inoue T

更新日期：2019-03-01 00:00:00