Takotsubo-shaped cardiomyopathy with type I CD36 deficiency.

Abstract:

:A transient left ventricular apical ballooning (so-called "ampulla" or "Takotsubo-shaped" cardiomyopathy) with type I CD36 deficiency is described in a 71-year-old woman. The patient was referred because of chest pain and worsening of dyspnea. Electrocardiogram showed T-wave inversions on the precordal leads, and acute coronary syndrome was suspected. Left ventricular apical ballooning was observed by echocardiogram and left ventriculography, and coronary arteriography did not reveal any significant stenosis. Left ventricular motion normalized at the follow-up period and there were no increases in specific markers for myocardial damage, such as myocardial band fraction of creatine kinase and troponin T, through out the admission. 123I-metaiodobengylguanidine myocardial single photon emission computed tomography (SPECT) revealed decreased accumulation areas at the apex, while 201Tl SPECT showed normal accumulation. An abnormal metabolism of cardiac free fatty acid was suggested by lack of accumulation of 123I beta-methyliodophenyl pentadecanoic acid (BMIPP) SPECT. No CD36 expression in either platelets or monocytes/macrophages was shown using flow cytometer analysis and type I CD36 deficiency was diagnosed. DNA sequencing showed that the patient had compound heterozygosity of the CD36 gene (a nucleotide change in C478T and an adenine insertion at nucleotide 1159 in exon 10). Although CD36 deficiency is thought to be involved with many cardiovascular disease and metabolic abnormalities, Takotsubo-shaped cardiomyopathy with CD36 deficiency had not been reported. Further studies of Takotsubo-shaped cardiomyopathy and CD36 deficiency may reveal an association between this cardiomyopathy and specific genetic profiles.

journal_name

Heart Vessels

journal_title

Heart and vessels

authors

Kushiro T,Saito F,Kusama J,Takahashi H,Imazeki T,Tani S,Kikuchi S,Imai S,Matsudaira K,Watanabe I,Hino T,Sato Y,Nakayama T,Nagao K,Kanmatsuse K

doi

10.1007/s00380-004-0787-3

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

123-5

issue

3

eissn

0910-8327

issn

1615-2573

journal_volume

20

pub_type

杂志文章
  • Hepatocyte growth factor(HGF): a new biochemical marker for acute myocardial infarction.

    abstract::The purpose of this study was to investigate the use of hepatocyte growth factor as a biochemical marker for acute myocardial infarction. Several biochemical markers are used for noninvasive detection of acute myocardial infarction. However, hepatocyte growth factor has not been used previously for this purpose. We me...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF02766790

    authors: Sato T,Yoshinouchi T,Sakamoto T,Fujieda H,Murao S,Sato H,Kobayashi H,Ohe T

    更新日期:1997-01-01 00:00:00

  • Effects of elastase on contractility and morphology of elastic tissue in isolated guinea pig papillary muscles.

    abstract::Elastase (ELA) is an enzyme catalyzing the digestion of elastin, an essential constituent of elastic fibers. Using isolated guinea pig papillary muscles, we examined the effect of ELA (3 x 10(-7) -3 x 10(-4) g/ml) on resting tension (RT) and twitch tension (TT). The effects of ELA on elastic fibers located in the sube...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF01744386

    authors: Sato T,Imanishi S,Arita M,Shimada T

    更新日期:1993-01-01 00:00:00

  • Successful repair of a large aortic abscess causing apical displacement of the anterior mitral valve.

    abstract::Anatomic continuity between the anterior mitral leaflet and the aortic root may predispose those patients with aortic root pathology to functional changes of the mitral valve without any involvement of this valve. A 34-year-old man presented with aortic valve endocarditis. Transthoracic echocardiograpy showed severe a...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-004-0761-0

    authors: Gunay I,Mert M,Kucukoglu S,Ozkan AA,Okcun B

    更新日期:2005-02-01 00:00:00

  • Analysis of 10-year nationwide population-based data on sex differences in hospitalization for heart failure.

    abstract::Sex-related factors play an important role in the pathophysiology of heart failure (HF). However, trends in sex-related differences in hospital management for HF are not clear. We identified patients hospitalized for HF through a nationwide database (National Health Insurance in Taiwan), containing 722,272 subjects fr...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-012-0299-5

    authors: Yang HY,Chiu WC,Huang JH,Hsu CY,Lin YK,Chen YJ

    更新日期:2013-11-01 00:00:00

  • Regional work of the ventricle: wall tension--area relation.

    abstract::We clarified that the set of the isotropic component (T) of wall tension and the area (A) of a selected region of the left ventricular wall expresses the regional work with sufficient accuracy. The area surrounded by the locus of the T-A relation in the T-A plane is approximately equal to the real work done by that re...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF02066408

    authors: Sugawara M,Tamiya K,Nakano K

    更新日期:1985-08-01 00:00:00

  • Cardiovascular medicine heart failure (CVM-HF) index as prognostic model for candidates to MitraClip therapy.

    abstract::Transcatheter MitraClip repair is a new tool for the management of severe mitral regurgitation in patients at very high risk for conventional surgery. Aim of our study was reporting one-year clinical outcomes in candidates to MitraClip procedures, divided into three groups according to the cardiovascular medicine hear...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-015-0772-z

    authors: Ussia GP,Cammalleri V,Mazzotta E,Pascuzzo G,Muscoli S,Marchei M,Macrini M,Anceschi A,Romeo F

    更新日期:2016-10-01 00:00:00

  • Vasoconstrictor effects of endogenous digitalis-like factors extracted from urine of hypertensive patients.

    abstract::The vascular effects of endogenous digitalis-like factors (EDLFs) extracted from the urine of hypertensive patients were investigated in isolated and perfused intermediate auricular and mesenteric arterial preparations of dogs. EDLFs produced a transient vasoconstriction in a dose-related manner in intermediate auricu...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF02058788

    authors: Chiba S,Tsukada M,Katsuyama Y,Tada A,Zenda H

    更新日期:1987-01-01 00:00:00

  • Increased C-reactive protein is associated with future development of diabetes mellitus in essential hypertensive patients.

    abstract::Coexistence of hypertension and diabetes mellitus (DM) increases the risk of cardiovascular disease. However, factors associated with future development of DM have not been well elucidated in patients already having essential hypertension. This study prospectively included 168 patients (mean age 41 +/- 7 years, 112 me...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-009-1218-2

    authors: Weng CM,Chou CH,Huang YY,Lin CC,Liu YW,Tsai WC

    更新日期:2010-09-01 00:00:00

  • Longer coronary anastomosis provides lower energy loss in coronary artery bypass grafting.

    abstract::Distal anastomosis technique affects graft patency and long-term outcomes in coronary artery bypass grafting, however, there is no standard for the appropriate length of distal anastomosis. The purpose of this study is to evaluate whether longer distal anastomosis provides higher quality of distal anastomosis and bett...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-016-0880-4

    authors: Tsukui H,Shinke M,Park YK,Yamazaki K

    更新日期:2017-01-01 00:00:00

  • Efficacy and safety of novel epicardial circumferential left atrial ablation with pulmonary vein isolation in sustained atrial fibrillation.

    abstract::The aim of this study was to examine the efficacy and safety of this novel epicardial circumferential left atrial ablation (CLAA) with pulmonary vein isolation (PVI) in sustained atrial fibrillation (AF). Thirty domestic pigs were divided equally into 3 groups: AF without ablation (AF group), AF with PVI (PVI group), ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-014-0594-4

    authors: Jiang Z,Yin H,He Y,Ma N,Tang M,Liu H,Ding F,Mei J

    更新日期:2015-09-01 00:00:00

  • The efficacy of everolimus-eluting stent implantation in patients with ST-segment elevation myocardial infarction: outcomes of 2-year clinical follow-up.

    abstract::First-generation drug-eluting stents (DES) demonstrated delay in vascular healing and increase in incidence of late and very late stent thrombosis compared with bare-metal stents (BMS). Second-generation DES, however, have shown a reduction of late and very late stent thrombosis compared with first-generation DES. Thu...

    journal_title:Heart and vessels

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00380-015-0783-9

    authors: Yano H,Horinaka S,Ishikawa M,Ishimitsu T

    更新日期:2016-10-01 00:00:00

  • Reduction of inorganic phosphate-induced human smooth muscle cells calcification by inhibition of protein kinase A and p38 mitogen-activated protein kinase.

    abstract::High levels of serum phosphate are associated with calcification of human smooth muscle cells (HSMCs). We investigated whether inhibition of protein kinase A (PKA) and mitogen-activated protein kinase (MAPK) signals [p38, extracellular signal-regulated kinase (ERK), and c-Jun N-terminal kinase (JNK)] can reduce inorga...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-013-0427-x

    authors: Kang JH,Toita R,Asai D,Yamaoka T,Murata M

    更新日期:2014-09-01 00:00:00

  • Echocardiographic surrogates of right atrial pressure in pulmonary hypertension.

    abstract::Right atrial pressure (RAP), a representative parameter of right heart failure, is very important for prognostic evaluation and risk assessment in pulmonary hypertension. However, its measurement requires invasive cardiac catheterization. In this study, we determined the most accurate echocardiographic surrogate of ca...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-018-1264-8

    authors: Watanabe R,Amano H,Saito F,Toyoda S,Sakuma M,Abe S,Nakajima T,Inoue T

    更新日期:2019-03-01 00:00:00

  • Expression of vascular endothelial growth factor in human myocardial infarction.

    abstract::To define mechanisms that may influence collateral circulation and angiogenesis, we investigated vascular endothelial growth factor (VEGF) mRNA expression in human hearts. In non-ischemic human hearts, VEGF mRNA was not detected in vessels, but was found in cardiomyocytes. In hearts with myocardial infarction, the int...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF01745169

    authors: Shinohara K,Shinohara T,Mochizuki N,Mochizuki Y,Sawa H,Kohya T,Fujita M,Fujioka Y,Kitabatake A,Nagashima K

    更新日期:1996-01-01 00:00:00

  • ZBTB17 loss-of-function mutation contributes to familial dilated cardiomyopathy.

    abstract::Dilated cardiomyopathy (DCM) is a common primary myocardial disease leading to congestive heart failure, arrhythmia and sudden cardiac death. Increasing studies demonstrate substantial genetic determinants for DCM. Nevertheless, DCM is of substantial genetic heterogeneity, and the genetic basis for DCM in most patient...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-017-1110-4

    authors: Sun YM,Wang J,Xu YJ,Wang XH,Yuan F,Liu H,Li RG,Zhang M,Li YJ,Shi HY,Zhao L,Qiu XB,Qu XK,Yang YQ

    更新日期:2018-07-01 00:00:00

  • Protective effect of coenzyme Q10 on thyrotoxic heart in rabbits.

    abstract::An excess of thyroid hormone is known to produce cardiac dysfunction and failure, i.e., thyrotoxic heart. We studied the protective effect of coenzyme Q10 (CoQ10) on the thyrotoxic heart in 29 rabbits. A group treated with 1-thyroxine sodium salt (T4; 167 micrograms/kg) for 3 weeks showed marked decreases in the myoca...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF02058524

    authors: Kotake C,Ito Y,Yokoyama M,Fukuzaki H

    更新日期:1987-01-01 00:00:00

  • Lower heart rate in the early postoperative period does not correlate with long-term outcomes after repair of type A acute aortic dissection.

    abstract::Little evidence exists regarding the need for a reduction in postoperative heart rate after repair of type A acute aortic dissection. This single-center retrospective study was conducted to determine if lower heart rate during the early postoperative phase is associated with improved long-term outcomes after surgery f...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-014-0486-7

    authors: Ohnuma T,Kimura N,Sasabuchi Y,Asaka K,Shiotsuka J,Komuro T,Mouri H,Lefor AT,Adachi H,Sanui M

    更新日期:2015-05-01 00:00:00

  • Aortic annulus angulation does not attenuate procedural success of transcatheter aortic valve replacement using a novel self-expanding bioprosthesis.

    abstract::The objectives of the study were to evaluate the impact of aortic angulation (AA) on success of transcatheter aortic valve replacement (TAVR) with a new generation self-expandable prosthesis (Medtronic Evolut R®). Specific anatomical conditions, such as for example the presence of a horizontal aorta with elevated AA, ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-019-01436-8

    authors: D'Ancona G,Kische S,El-Mawardy M,Dißmann M,Heinze H,Zohlnhöfer-Momm D,Gürer H,Ince H

    更新日期:2019-12-01 00:00:00

  • Altered expression of Na+ transporters at the mRNA level in rat normal and hypertrophic myocardium.

    abstract::Intracellular Na(+) ([Na(+)](i)) regulation plays a crucial role in the structural, mechanical, and electrical properties of myocardium. It is assumed that the [Na(+)](i) handling system may differ not only between normal and diseased hearts but also regionally within a heart. To gain new insight concerning disease- a...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-008-1071-8

    authors: Yamamoto T,Shirayama T,Takahashi T,Matsubara H

    更新日期:2009-01-01 00:00:00

  • Changes in coagulation and fibrinolytic parameters caused by extracorporeal circulation.

    abstract::During cardiopulmonary bypass (CPB) mechanical stress and the contact of blood with artificial surfaces lead to the activation of pro- and anticoagulant systems and the complement cascade, and to changes in cellular components. This phenomenon causes the "postperfusion-syndrome", with leukocytosis, increased capillary...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF01747190

    authors: Grossmann R,Babin-Ebell J,Misoph M,Schwender S,Neukam K,Hickethier T,Elert O,Keller F

    更新日期:1996-01-01 00:00:00

  • Our tortuous heart in dynamic mode--an echocardiographic study of mitral flow and movement in exercising subjects.

    abstract::Blood traces tortuous paths of flow through the heart. We postulate that momentum changes associated with direction changes optimize dynamic coupling between ventricular and atrial function, particularly on exercise. Traces of pulsed Doppler mitral flow and M-mode long-axis mitral ring movement were recorded before an...

    journal_title:Heart and vessels

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02767127

    authors: Kilner PJ,Henein MY,Gibson DG

    更新日期:1997-01-01 00:00:00

  • Effects of dietary sodium on reactive oxygen species formation and endothelial dysfunction in low-density lipoprotein receptor-deficient mice on high-fat diet.

    abstract::Hypertension and high serum cholesterol level are important risk factors for atherosclerosis and coronary heart disease. In the present study we tested the hypothesis whether high sodium intake, when given in combination with Western type high-fat diet, induces endothelial dysfunction and promotes atherosclerosis. Fur...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-008-1066-5

    authors: Ketonen J,Mervaala E

    更新日期:2008-11-01 00:00:00

  • Noninvasive assessment of acute cardiopulmonary effects of an oral single dose of sildenafil in patients with idiopathic pulmonary hypertension.

    abstract::We aimed to assess the acute cardiopulmonary effects of a 100-mg oral single dose of sildenafil in patients with idiopathic pulmonary hypertension (IPAH) using a well-validated but less-used noninvasive echocardiographic method for the measurement of both systolic and diastolic pulmonary artery pressure (PAP), by tric...

    journal_title:Heart and vessels

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00380-009-1208-4

    authors: Behzadnia N,Najafizadeh K,Sharif-Kashani B,Dameshghi DO,Shahabi P

    更新日期:2010-07-01 00:00:00

  • The relationship between systolic vector flow mapping parameters and left ventricular cardiac function in healthy dogs.

    abstract::Vector flow mapping (VFM) is a novel echocardiographic technology that shows blood flow vectors and vortexes, enabled the hydrokinetic evaluation of hemodynamics within the left ventricle. VFM provides several unique parameters: circulation, vorticity, vortex area, and energy loss. The present study aims to reveal a r...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-017-1093-1

    authors: Goya S,Wada T,Shimada K,Hirao D,Tanaka R

    更新日期:2018-05-01 00:00:00

  • Role of myocardial interstitial edema in conduction disturbances in acute myocarditis.

    abstract::The presence of myocardial interstitial edema in acute myocarditis (AM) leads to thickening of the ventricular wall, and conduction disturbances, such as complete atrioventricular block (CAV), also frequently develop. This study was undertaken in order to clarify the relationship between conduction disturbances and my...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-006-0922-4

    authors: Morimoto S,Kato S,Hiramitsu S,Uemura A,Ohtsuki M,Kato Y,Sugiura A,Miyagishima K,Yoshida Y,Hishida H

    更新日期:2006-11-01 00:00:00

  • Clinical characteristics and prognostic factors in acute coronary syndrome patients complicated with cardiogenic shock in Japan: analysis from the Japanese Circulation Society Cardiovascular Shock Registry.

    abstract::Cardiogenic shock frequently leads to death even with intensive treatment. Although the leading cause of cardiogenic shock is acute coronary syndrome (ACS), the clinical characteristics and the prognosis of ACS with cardiogenic shock in the present era still remain to be elucidated. We analyzed clinical characteristic...

    journal_title:Heart and vessels

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00380-019-01354-9

    authors: Sakamoto K,Matoba T,Mohri M,Ueki Y,Tsujita Y,Yamasaki M,Tanaka N,Hokama Y,Fukutomi M,Hashiba K,Fukuhara R,Suwa S,Matsuura H,Tachibana E,Yonemoto N,Nagao K

    更新日期:2019-08-01 00:00:00

  • Assessment of vascular autonomic function using peripheral arterial tonometry.

    abstract::Peripheral autonomic function is impaired in diabetic polyneuropathy. However, it is difficult to evaluate it due to the lack of non-invasive quantitative assessment. We aimed to establish a novel index to evaluate vascular autonomic function using reactive hyperemia peripheral arterial tonometry (RH-PAT), a widely pe...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-016-0870-6

    authors: Hamada S,Oono A,Ishihara Y,Hasegawa Y,Akaza M,Sumi Y,Inoue Y,Izumiyama H,Hirao K,Isobe M,Sasano T

    更新日期:2017-03-01 00:00:00

  • Serum carboxy-terminal telopeptide of type I collagen (I-CTP) is predictive of clinical outcome in peripheral artery disease patients following endovascular therapy.

    abstract::Peripheral artery disease (PAD) is a risk factor for the development of heart failure and mortality. The serum levels of carboxy-terminal telopeptide of type I collagen (I-CTP), a marker for collagen degradation derived from the extracellular matrix of vascular and myocardial tissue, is reportedly a useful marker for ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-016-0858-2

    authors: Otaki Y,Watanabe T,Takahashi H,Yamaura G,Nishiyama S,Arimoto T,Shishido T,Miyamoto T,Kubota I

    更新日期:2017-02-01 00:00:00

  • Aneurysmal aorto-left ventricular tunnel causing right ventricular outflow tract obstruction, associated with bicuspid aortic valve.

    abstract::We report the case of a newborn with an aneurysmal aorto-left ventricular tunnel causing significant paravalvular aortic regurgitation and obstruction of the right ventricular outflow tract (RVOT), coexisting with a bicuspid aortic valve. The coexistence of the two malformations together with the obstruction of the RV...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-013-0445-8

    authors: Toganel R,Benedek T,Suteu C,Benedek I

    更新日期:2015-01-01 00:00:00

  • More coronary artery stenosis, more cerebral artery stenosis? A simultaneous angiographic study discloses their strong correlation.

    abstract::Cerebral artery stenosis (CAS) has the same pathogenesis as coronary artery disease (CAD), but the coexistence of these two diseases has been rarely reported. To detect coexistent CAS in CAD patients, we conducted a study of simultaneous coronary and cerebral angiography. Of the 663 consecutive newly diagnosed CAD pat...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-006-0971-8

    authors: Li AH,Chu YT,Yang LH,Chen KC,Chu SH

    更新日期:2007-09-01 00:00:00