Abstract：
:Obesity is generally associated with low-grade chronic inflammation that involves the recruitment of macrophages and other inflammation factors to the adipocytes of obese individuals. Tumor necrosis factor-alpha (TNF-α), a cytokine associated with systemic inflammation, is elevated in conditions of obesity. TNF-α is an important factor that plays an important role in skeletal muscle wasting. Apoptosis of myonuclei contributes to the loss of muscle mass and therefore plays an important role in skeletal muscle atrophy. In mouse models that were fed a high fat diet (HFD), a lipolysis-stimulating peptide-VHVV (purified from hydrolysate resulting from flavourzyme treatment of soy protein) was found to reduce HFD-related apoptotic effects in mice skeletal muscle and potentially control atrophy. HFD fed mice had heavier body weight than those fed with normal chow, and VHVV administration restricted lipid accumulation in muscle tissues of mice fed with HFD but increased nutrient uptake. Moreover, specific concentrations of VHVV regulated TNF-α expression that was elevated by HFD, suppressed apoptosis-related proteins and regulated the proteins of lipid metabolism.
journal_name
J Med Foodjournal_title
Journal of medicinal foodauthors
Marthandam Asokan S,Hung TH,Chiang WD,Lin WTdoi
10.1089/jmf.2017.3941subject
Has Abstractpub_date
2018-03-01 00:00:00pages
225-232issue
3eissn
1096-620Xissn
1557-7600journal_volume
21pub_type
杂志文章abstract：:The oxygen radical absorbance capacity (ORAC) assay has been widely used to quantify peroxyl radical scavenging capacity of pure antioxidant compounds and antioxidant plant/food extracts. However, it has never been applied to natural compounds derived from microalgae-based dietary supplements, namely, phycocyanin (PC)...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2008.0257
更新日期：2010-02-01 00:00:00
abstract：:The purpose of this study was to investigate the effects of a proprietary blend of soybean peptides, taurine, Pueraria isoflavone, and ginseng saponin complex (STPG capsule) on exercise performance in humans. Fourteen male volunteers were randomly assigned to two crossover treatments in which they consumed either four...
journal_title：Journal of medicinal food
pub_type： 杂志文章,随机对照试验
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更新日期：2011-03-01 00:00:00
abstract：:We have provided a protocol for establishing an atopic dermatitis (AD) in vitro model, and evaluated the effects of Costaria costata (CC) extracts on AD in an in vitro model using keratinocytes and splenocytes from AD-induced mice and mast cells. HaCaT cells were each treated with 200 μg/mL of CC water extract (CCW), ...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2016.3691
更新日期：2016-10-01 00:00:00
abstract：:Several biological and clinical studies have suggested that conjugated linoleic acid (CLA) prevents body fat accumulation and increases lean body mass. CLA is available as a concentrated dietary supplement and is purported to provide the aforementioned benefits for people who perform physical activity. This study was ...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2011.0144
更新日期：2012-04-01 00:00:00
abstract：:Fermentation has shown to be an effective technique in bioactive peptides release. That is why in this study antihypertensive, antithrombotic, and antioxidant activity was evaluated during amaranth proteins fermentation with Lactobacillus casei Shirota and Streptococcus thermophilus 54102 in mono and combined culture....
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2019.0039
更新日期：2019-10-01 00:00:00
abstract：:Essential oil preparation of the terpenic type was introduced for the first time in the 1930s for the management of urolithiasis. Although essential oil preparations are registered in 50 countries, including some developed countries such as the United Kingdom, Italy, and Japan, for use in urolithiasis, no literature h...
journal_title：Journal of medicinal food
pub_type： 杂志文章,评审
doi：10.1089/jmf.2008.0115
更新日期：2010-04-01 00:00:00
abstract：:To observe the effects of marine collagen peptides (MCPs) prepared from chum salmon (Oncorhynchus keta) skin on life span and spontaneous tumor incidence, Sprague-Dawley rats were fed diets supplemented with MCP at concentrations of 0%, 2.25%, 4.5%, and 9% (wt/wt) from the age of 4 weeks until natural death. There wer...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2009.1279
更新日期：2010-08-01 00:00:00
abstract：:Tagatose, a low-calorie, full-bulk natural sugar, has just attained GRAS (Generally Recognized As Safe) status under U.S. Food and Drug Administration (FDA) regulations, thereby permitting its use as a sweetener in foods and beverages. This paper presents all current aspects of tagatose with respect to demonstrated fo...
journal_title：Journal of medicinal food
pub_type： 杂志文章,评审
doi：10.1089/109662002753723197
更新日期：2002-04-01 00:00:00
abstract：:The effect of the administration of a whey protein isolate (WPI) and collagen hydrolysates on ethanol-induced ulcerative lesions was studied in rats. WPI and bovine or porcine collagen hydrolysate (BCH and PCH, respectively) were given to rats by gavage. In acute experiments, (single-dose) physiological saline (10 mL/...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2008.0277
更新日期：2010-02-01 00:00:00
abstract：:Ultraviolet (UV) light is a physical carcinogen, and UV irradiation from sunlight has negative effects on human skin. UVB-induced inflammation is linked to excessive induction of various inflammatory cytokines/chemokines in many types of cells, including keratinocytes. The purpose of this study was to investigate the ...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2009.1239
更新日期：2010-06-01 00:00:00
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journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2005.067
更新日期：2007-03-01 00:00:00
abstract：:This study evaluated the antioxidant and protective effects of bioactive compounds isolated from pressurized steam-treated Corni Fructus (PSC). We had previously tested the protective effects of the furan fraction containing 5-hydroxymethylfurfural (5-HMF), polyphenol fraction containing gallic acid, and iridoid glyco...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2017.4149
更新日期：2018-11-01 00:00:00
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journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2011.1851
更新日期：2012-03-01 00:00:00
abstract：:High glucose levels can change podocyte gene expression and subsequently induce podocyte damage through altered glucose metabolism. l-Carnitine is known to play a beneficial role in diabetes; however, there are no studies on the effects of l-carnitine on podocyte alteration under high glucose conditions. This study in...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2010.1079
更新日期：2010-12-01 00:00:00
abstract：:In Mexican traditional medicine the orchid Prosthechea michuacana is highly valued as a food and in the treatment of various human diseases, including drug-related renal disease. Methanol, hexane, and chloroform extracts of bulbs of P. michuacana were studied in the cisplatin-induced renal injury model in rats. Result...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2009.0175
更新日期：2010-08-01 00:00:00
abstract：:Oxidative stress and hypogonadism are two factors linked to the increased incidence of cardiovascular disease in males. Eating fruits and vegetables is known to reduce the incidences of oxidative stress. The objective of this research was to delineate whether drinking daily squeezed orange juice (OJ) or grapefruit jui...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2006.9.422
更新日期：2006-10-01 00:00:00
abstract：:Soy products are mainly composed of proteins, phytochemicals such as isoflavones, soy lipids, and carbohydrates. It is unclear whether an individual component alone or a combined effect of multiple bioactive compounds contributes to the beneficial properties of soy. We investigated the effect of dietary genistein (the...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2006.9.459
更新日期：2006-01-01 00:00:00
abstract：:In South America, particularly in the Northeastern regions of Brazil, Turnera subulata leaf extract is used as an alternative traditional medicine approach for several types of chronic diseases, such as diabetes, hypertension, chronic pain, and general inflammation. Despite its widespread use, little is known about th...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2016.0047
更新日期：2016-10-01 00:00:00
abstract：:This study evaluates the effects of green tea polyphenols (GTPs) on bone microarchitecture in high-fat-diet (HFD)-induced obese female rats. Thirty-six 3-month-old female rats were fed either a control diet or a HFD for 4 months. Animals in the control group continued on the control diet for another 4 months. Animals ...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2012.0199
更新日期：2013-05-01 00:00:00
abstract：:Glucomannan-enriched squid surimi improves cholesterolemia and liver antioxidant status. The effect of squid surimi enriched with glucomannan or glucomannan plus spirulina on liver and heart structures and cell damage markers was tested in fa/fa rats fed highly saturated-hyper-energetic diets. Animals were fed 70% AIN...
journal_title：Journal of medicinal food
pub_type： 杂志文章
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更新日期：2017-06-01 00:00:00
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journal_title：Journal of medicinal food
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doi：10.1089/jmf.2011.0226
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journal_title：Journal of medicinal food
pub_type： 杂志文章
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更新日期：2011-04-01 00:00:00
abstract：:Extracts of Cissus quadrangularis L. were tested for antioxidant activity by beta-carotene linoleic acid model and also by 1,1-diphenyl-2-picrylhydrazyl model. The ethyl acetate fraction of both fresh and dry stem extracts at a concentration of 100 ppm showed 64.8% antioxidant activity in the beta-carotene linoleic ac...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/109662003322233495
更新日期：2003-07-01 00:00:00
abstract：:Recent studies have determined that gastrointestinal function contributes to the control of Parkinson's disease (PD). Gastrointestinal dysfunction results in a leaky intestinal barrier, inducing inflammation in the gut. Korean red ginseng (KRG) is widely used for the treatment of numerous afflictions, including inflam...
journal_title：Journal of medicinal food
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更新日期：2020-12-01 00:00:00
abstract：:The transport behavior and absorption mechanism of Ala-His-Leu-Leu (AHLL) intestinal absorption in Caco-2 cell monolayers were clarified systemically. The safe absorptive concentration of AHLL was 200 μg/mL, which was determined by the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay. The permeat...
journal_title：Journal of medicinal food
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更新日期：2017-03-01 00:00:00
abstract：:Advanced glycation endproducts and oxidative stress contribute to the pathogenesis of diabetic complications. The total phenolic content (TPC), antioxidant, and antiglycation properties of crude ethanolic extracts of 10 common culinary herbs and spices from Mauritius were investigated in vitro. Fluorescence at 370 nm/...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2012.0113
更新日期：2012-12-01 00:00:00
abstract：:This study aimed to assess the effects of a yacon-based product (YBP) on constipation in adults, including the elderly. Forty-eight individuals were recruited and divided into equal intervention groups named the test and control groups. The YBP (test) and the control (maltodextrin) were dissolved in commercial orange ...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2014.0115
更新日期：2015-09-01 00:00:00
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journal_title：Journal of medicinal food
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更新日期：2011-03-01 00:00:00
abstract：:The quantitative distribution of flavan-3-ols was determined using high-performance liquid chromatography in several grape seed extracts (GSEs). In all GSEs, polymers of four or more carbon units were the group of procyanidins present in the highest concentration, the real quantity ranging between 60% and 99.5%. In a ...
journal_title：Journal of medicinal food
pub_type： 杂志文章
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更新日期：2001-07-01 00:00:00
abstract：:Telfairia occidentalis (Cucurbitaceae) is a leafy vegetable used in soup and folk medicine in southern Nigeria. Ethnobotanical survey revealed that preparations of the plant are used in the treatment of central nervous system-related disorders including convulsion. This study was conducted to investigate the effect of...
journal_title：Journal of medicinal food
pub_type： 杂志文章
doi：10.1089/jmf.2012.0211
更新日期：2013-09-01 00:00:00
