Supplementation with soybean peptides, taurine, Pueraria isoflavone, and ginseng saponin complex improves endurance exercise capacity in humans.


:The purpose of this study was to investigate the effects of a proprietary blend of soybean peptides, taurine, Pueraria isoflavone, and ginseng saponin complex (STPG capsule) on exercise performance in humans. Fourteen male volunteers were randomly assigned to two crossover treatments in which they consumed either four STPG capsules (STPG treatment) or placebo (P treatment) for 15 days before a 75% maximal oxygen uptake (VO(2max)) exhaustive cycling test. Blood samples and respiratory gas were collected prior to the exercise (Pre-Ex), at 10 (Ex-10), 15 (Ex-15), 20 (Ex-20), and 25 (Ex-25) minutes during exercise, and immediately after exercise (exhaustion) to assess the blood metabolites, cardiorespiratory responses, and energy substrate utilization. The result showed that exercise time to exhaustion of the 75% (VO(2max)) exhaustive cycling test of the STPG-treated subjects was significantly greater than with the P treatment (30.99 ± 2.01 vs. 28.05 ± 1.48 minutes). The plasma lactate concentrations at Ex-20 and Ex-25 in the STPG treatment were significantly lower with STPG treatment than with P treatment (10.5 ± 0.7 vs. 11.5 ± 0.8 and 10.7 ± 0.9 vs.12.3 ± 1.0 mmol/L, respectively). Nonesterified fatty acid levels at Ex-15, Ex-20, Ex-25, and exhaustion in the STPG group (0.27 ± 0.03, 0.32 ± 0.04, 0.32 ± 0.06, and 0.37 ± 0.05 mmol/L, respectively) were significantly higher than those in the P treatment (0.21 ± 0.03, 0.23 ± 0.03, 0.24 ± 0.03, and 0.25 ± 0.03 mmol/L, respectively). It was concluded that supplementation of four capsules (2 g) of STPG complex, consisting of soybean peptides, taurine, Pueraria isoflavone, and ginseng saponin, for 15 days was effective in promoting utilization of free fatty acids and improving exhaustive cycling test performance in humans.


J Med Food


Yeh TS,Chan KH,Hsu MC,Liu JF




Has Abstract


2011-03-01 00:00:00












  • No Synergistic Effect of Silibinin and Morin in a Kainic Acid-Induced Epileptic Mouse Model.

    abstract::Temporal lobe epilepsy (TLE) is the most common form of localization-related epilepsy, with the highest prevalence rate in adulthood. Recently, we reported the beneficial effects of the individual treatment with flavonoids such as silibinin and morin in kainic acid (KA)-treated mouse model for TLE. In this study, we i...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Hong J,Lee JM,Yoon D,Jung UJ,Kim SR

    更新日期:2020-02-01 00:00:00

  • Modulation of doxorubicin-induced oxidative stress by a grape (Vitis vinifera L.) seed extract in normal and tumor cells.

    abstract::The major limitation of Doxorubicin (Dox) clinical use is the development of chronic and acute toxic side effects induced through the generation of reactive oxygen species. The present work was designated to investigate in vitro effects of a red grape-seed hydroethanolic extract Burgund Mare (BM), in associated admini...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Postescu ID,Chereches G,Tatomir C,Daicoviciu D,Filip GA

    更新日期:2012-07-01 00:00:00

  • Almond Skin Polyphenol Extract Inhibits Inflammation and Promotes Lipolysis in Differentiated 3T3-L1 Adipocytes.

    abstract::Studies have shown that polyphenols reduce the risk of inflammation-related diseases and upregulates energy expenditure in adipose tissue. Here, we investigated the mechanism of the anti-inflammatory and antiobesity effects of almond skin polyphenol extract (ASP) in differentiated 3T3-L1 adipocytes. The antioxidant ef...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Huang WC,Chen CY,Wu SJ

    更新日期:2017-02-01 00:00:00

  • Antioxidant and antimicrobial activity of Cissus quadrangularis L.

    abstract::Extracts of Cissus quadrangularis L. were tested for antioxidant activity by beta-carotene linoleic acid model and also by 1,1-diphenyl-2-picrylhydrazyl model. The ethyl acetate fraction of both fresh and dry stem extracts at a concentration of 100 ppm showed 64.8% antioxidant activity in the beta-carotene linoleic ac...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Chidambara Murthy KN,Vanitha A,Mahadeva Swamy M,Ravishankar GA

    更新日期:2003-07-01 00:00:00

  • Thyme (Thymus vulgaris L.) leaves and its constituents increase the activities of xenobiotic-metabolizing enzymes in mouse liver.

    abstract::The effects of thyme (Thymus vulgaris L.) leaves and its phenolic compounds, thymol and carvacrol, on the activities of xenobiotic-metabolizing enzymes, i.e., phase I enzymes such as 7-ethoxycoumarin O-deethylase (ECOD) and phase II enzymes such as glutathione S-transferase (GST) and quinone reductase (QR), were inves...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Sasaki K,Wada K,Tanaka Y,Yoshimura T,Matuoka K,Anno T

    更新日期:2005-07-01 00:00:00

  • The potential effects of ethyl acetate fraction from Curcuma longa L. on lipolysis in differentiated 3T3-L1 adipocytes.

    abstract::The effects of the turmeric ethyl acetate fraction (TEF) from the methanolic extract from Curcuma longa L. on lipid metabolism and underlying mechanisms of lipolysis were investigated in 3T3-L1 adipocytes. The intracellular lipid droplets were stained with Oil red O dye and quantified. Compared to the control, lipid a...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Lee J,Yoon HG,Lee YH,Park J,You Y,Kim K,Jang JY,Yang JW,Jun W

    更新日期:2010-04-01 00:00:00

  • Efficacy and acceptance of a commercial Hoodia parviflora product for support of appetite and weight control in a consumer trial.

    abstract::Species of Hoodia Sweet ex Decne., family Apocynaceae, a southern African succulent plant, have been recognized for their appetite suppressing properties. Products that support appetite and weight control have been developed in Israel from locally cultivated Hoodia spp. To study consumer acceptance, efficacy of, and t...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章,随机对照试验


    authors: Landor M,Benami A,Segev N,Loberant B

    更新日期:2015-02-01 00:00:00

  • Antibacterial Investigation of Thyme Essential Oil and Its Main Constituents in Combination with Tetracycline.

    abstract::The chemical composition and antibacterial activity of Thymus glabrescens Willd. (thyme) essential oil were examined, as well as its association with tetracycline. The antibacterial activities of geraniol and thymol, the main constituents of T. glabrescens oil, were also determined. Gas chromatography and gas chromato...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Miladinović DL,Ilić BS,Kocić BD,Ćirić VM,Nikolić DM

    更新日期:2015-08-01 00:00:00

  • The Effects of Costaria costata Extracts on Atopic Dermatitis in an In Vitro Model.

    abstract::We have provided a protocol for establishing an atopic dermatitis (AD) in vitro model, and evaluated the effects of Costaria costata (CC) extracts on AD in an in vitro model using keratinocytes and splenocytes from AD-induced mice and mast cells. HaCaT cells were each treated with 200 μg/mL of CC water extract (CCW), ...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Kim OK,Nam DE,Lee M,Kwon HO,Park J,You Y,Kim SI,Lee J,Jun W

    更新日期:2016-10-01 00:00:00

  • Yacon-Based Product in the Modulation of Intestinal Constipation.

    abstract::This study aimed to assess the effects of a yacon-based product (YBP) on constipation in adults, including the elderly. Forty-eight individuals were recruited and divided into equal intervention groups named the test and control groups. The YBP (test) and the control (maltodextrin) were dissolved in commercial orange ...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: de Souza Lima Sant'Anna M,Rodrigues VC,Araújo TF,de Oliveira TT,do Carmo Gouveia Peluzio M,de Luces Fortes Ferreira CL

    更新日期:2015-09-01 00:00:00

  • Aqueous Extract of Humulus japonicus Attenuates Hyperlipidemia and Fatty Liver in Obese Mice.

    abstract::In this study, the effects of Humulus japonicus (HJ) aqueous extract on 3T3-L1 preadipocytes and HepG2 cells (in vitro model) as well as on C57BL/6 mice fed on high-fat diet (HFD) (in vivo model) were evaluated. Mice fed on HFD for 12-weeks were taken the HJ water extract (HJW) at various doses, 50, 150, and 250 mg/kg...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Chung YH,Bang JS,Kang CM,Goh JW,Lee HS,Hong SM,Kim DS,Park ES,Jung TW,Shin YK,Lee JH,Jeong JH

    更新日期:2018-10-01 00:00:00

  • Anticonvulsant activity of ethanol leaf extract of Spathodea campanulata P. Beauv (Bignoniaceae).

    abstract::The anticonvulsant properties of ethanol leaf extract of Spathodea campanulata, a plant used in traditional medicine to treat convulsion and epilepsy, were studied in mice using pentylenetetrazole-, picrotoxin-, and electroshock-induced models in mice. Other central nervous system effects and anticonvulsant-related ac...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Ilodigwe EE,Akah PA,Nworu CS

    更新日期:2010-08-01 00:00:00

  • Immunomodulatory properties of frondoside A, a major triterpene glycoside from the North Atlantic commercially harvested sea cucumber Cucumaria frondosa.

    abstract::Frondoside A, a major triterpene glycoside from North Atlantic commercially harvested sea cucumber Cucumaria frondosa, possesses strong immunomodulatory properties in subtoxic doses. Frondoside A stimulates lysosomal activity of mouse macrophages in vivo at a maximal effective stimulatory dose of 0.2 microg per mouse ...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Aminin DL,Agafonova IG,Kalinin VI,Silchenko AS,Avilov SA,Stonik VA,Collin PD,Woodward C

    更新日期:2008-09-01 00:00:00

  • The evaluation of nitric oxide scavenging activity of certain Indian medicinal plants in vitro: a preliminary study.

    abstract::The plant extracts of 17 commonly used Indian medicinal plants were examined for their possible regulatory effect on nitric oxide (NO) levels using sodium nitroprusside as an NO donor in vitro. Most of the plant extracts tested demonstrated direct scavenging of NO and exhibited significant activity. The potency of sca...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Jagetia GC,Baliga MS

    更新日期:2004-10-01 00:00:00

  • Effect of production batches of antibiotics on in vitro selection criterion for potential probiotic candidates.

    abstract::Fifty-four potential probiotic candidates were assayed for their phenotypic susceptibility to two batches of antibiotics manufactured by the same company, using the agar disc diffusion method on de Man, Rogosa, and Sharpe (MRS) agar. Cloxacillin was generally resisted (40.0-100%), while gentamicin (3.85-20.0%) was the...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Ogunshe AA

    更新日期:2008-12-01 00:00:00

  • Inhibition of nuclear transcription factor-κB and activation of peroxisome proliferator-activated receptors in HepG2 cells by cucurbitane-type triterpene glycosides from Momordica charantia.

    abstract::Momordica charantia is used to treat various diseases, including inflammatory conditions. Previous reports indicated that the extract of this plant inhibits activation of nuclear transcription factor-κB (NF-κB) but activates peroxisome proliferator-activated receptor (PPAR). Additionally, cucurbitane-type triterpene g...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Nhiem NX,Yen PH,Ngan NT,Quang TH,Kiem PV,Minh CV,Tai BH,Cuong NX,Song SB,Kim YH

    更新日期:2012-04-01 00:00:00

  • Oxygen radical absorbance capacity of phycocyanin and phycocyanobilin from the food supplement Aphanizomenon flos-aquae.

    abstract::The oxygen radical absorbance capacity (ORAC) assay has been widely used to quantify peroxyl radical scavenging capacity of pure antioxidant compounds and antioxidant plant/food extracts. However, it has never been applied to natural compounds derived from microalgae-based dietary supplements, namely, phycocyanin (PC)...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Benedetti S,Benvenuti F,Scoglio S,Canestrari F

    更新日期:2010-02-01 00:00:00

  • Inhibitory effects of salidroside on nitric oxide and prostaglandin E₂ production in lipopolysaccharide-stimulated RAW 264.7 macrophages.

    abstract::The aim of this study was to evaluate the effect of salidroside on lipopolysaccharide (LPS)-induced nitric oxide (NO) and prostaglandin E₂ (PGE₂) production in RAW 264.7 macrophages and related anti-inflammatory mechanism. PGE₂ production was measured by enzyme-linked immunosorbent assay (ELISA); NO production was tes...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Song B,Huang G,Xiong Y,Liu J,Xu L,Wang Z,Li G,Lu J,Guan S

    更新日期:2013-11-01 00:00:00

  • Cuscuta chinensis extract promotes osteoblast differentiation and mineralization in human osteoblast-like MG-63 cells.

    abstract::The aim of the present study was to investigate whether the aqueous extract of To-Sa-Za (TSZ-AE), the seed of Cuscuta chinensis Lam., which is a traditional medicinal herb commonly used in Korea and other oriental countries, could induce osteogenic activity in human osteoblast-like MG-63 cells. TSZ-AE treatment mildly...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Yang HM,Shin HK,Kang YH,Kim JK

    更新日期:2009-02-01 00:00:00

  • N-Oleoyl-Phosphatidyl-Ethanolamine and Epigallo Catechin-3-Gallate Mitigate Oxidative Stress in Overweight and Class I Obese People on a Low-Calorie Diet.

    abstract::Oxidative stress and lipid peroxidation are considered key factors linking obesity with its associated complications. Epigallo catechin-3-gallate (EGCG) and oleoylethanolamide, together with its phospholipid precursor N-oleoyl-phosphatidylethanolamine (NOPE), are nutritional compounds that might improve the oxidative ...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章,随机对照试验


    authors: Cazzola R,Rondanelli M

    更新日期:2020-03-01 00:00:00

  • Effects of heating, storage, and ultraviolet exposure on antimicrobial activity of garlic juice.

    abstract::This study was designed to investigate the effect of heating, storage, and ultraviolet exposure on antimicrobial activity of garlic juice and its bacteriocidal activity against common human pathogens. Antimicrobial activity of fresh garlic juice was tested against Escherichia coli, Staphylococcus aureus, Streptococcus...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Al-Waili NS,Saloom KY,Akmal M,Al-Waili TN,Al-Waili AN,Al-Waili H,Ali A,Al-Sahlani K

    更新日期:2007-03-01 00:00:00

  • High temperature- and high pressure-processed garlic improves lipid profiles in rats fed high cholesterol diets.

    abstract::Garlic protects against degenerative diseases such as hyperlipidemia and cardiovascular diseases. However, raw garlic has a strong pungency, which is unpleasant. In this study, we examined the effect of high temperature/high pressure-processed garlic on plasma lipid profiles in rats. Sprague-Dawley rats were fed a nor...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Sohn CW,Kim H,You BR,Kim MJ,Kim HJ,Lee JY,Sok DE,Kim JH,Lee KJ,Kim MR

    更新日期:2012-05-01 00:00:00

  • Effects of Stevia rebaudiana (Bertoni) extract and N-nitro-L-arginine on renal function and ultrastructure of kidney cells in experimental type 2 Diabetes.

    abstract::Diabetes is the leading cause of chronic renal failure. Our purpose was to determine the effects of N-nitro-l-arginine (l-NNA) and an extract of Stevia rebaudiana (Bertoni) (SrB) leaves on renal function in streptozotocin-nicotinamide (STZ-NA)-induced diabetic rats. Rats were divided into seven groups. Three of these ...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Ozbayer C,Kurt H,Kalender S,Ozden H,Gunes HV,Basaran A,Cakmak EA,Civi K,Kalender Y,Degirmenci I

    更新日期:2011-10-01 00:00:00

  • Myricetin protects against cytokine-induced cell death in RIN-m5f β cells.

    abstract::Cytokine-induced cell death is recognized as a major cause of progressive β-cell loss. Tumor necrosis factor α (TNF-α), interleukin 1β (IL-1β), and interferon γ (IFN-γ) in combination trigger a series of events that lead to β-cell death. In the past few decades, the use of myricetin as an anti-inflammatory and cytopro...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Ding Y,Zhang ZF,Dai XQ,Li Y

    更新日期:2012-08-01 00:00:00

  • Antihypertensive effects of Gynura procumbens extract in spontaneously hypertensive rats.

    abstract::Aqueous extracts of Gynura procumbens (Lour.) Merr. were orally administered to spontaneously hypertensive (SHR) rats for 4 weeks, and antihypertensive effects were determined. Oral administration of 500 mg/kg of G. procumbens (Lour.) Merr. extract (GPE) resulted in significantly lower blood pressure in SHR rats compa...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Kim MJ,Lee HJ,Wiryowidagdo S,Kim HK

    更新日期:2006-01-01 00:00:00

  • High environmental stress yields greater tocotrienol content while changing vitamin e profiles of wild emmer wheat seeds.

    abstract::Vitamin E is an essential human nutrient that was first isolated from wheat. Emmer wheat, the cereal of Old World agriculture and a precursor to durum wheat, grows wild in the Fertile Crescent. Evolution Canyon, Israel, provides a microsite that models effects of contrasting environments. The north-facing and south-fa...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Watts EJ,Shen Y,Lansky EP,Nevo E,Bobe G,Traber MG

    更新日期:2015-02-01 00:00:00

  • Influence of sesame oil on blood glucose, lipid peroxidation, and antioxidant status in streptozotocin diabetic rats.

    abstract::The present study was carried out to assess the influence of sesame oil on blood glucose, lipid peroxidation, and status of antioxidants in normal and streptozotocin (STZ) diabetic rats. Diabetes was induced in adult female albino Wistar rats weighing 180-200 g by administration of STZ (40 mg/kg of body weight) intrap...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Ramesh B,Saravanan R,Pugalendi KV

    更新日期:2005-10-01 00:00:00

  • Bioactivity of Peptides Released During Lactic Fermentation of Amaranth Proteins with Potential Cardiovascular Protective Effect: An In Vitro Study.

    abstract::Fermentation has shown to be an effective technique in bioactive peptides release. That is why in this study antihypertensive, antithrombotic, and antioxidant activity was evaluated during amaranth proteins fermentation with Lactobacillus casei Shirota and Streptococcus thermophilus 54102 in mono and combined culture....

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Ayala-Niño A,Rodríguez-Serrano GM,Jiménez-Alvarado R,Bautista-Avila M,Sánchez-Franco JA,González-Olivares LG,Cepeda-Saez A

    更新日期:2019-10-01 00:00:00

  • Increase of bioavailability of coenzyme Q(10) and vitamin E.

    abstract::Commercial coenzyme Q(10) (CoQ(10)) and alpha-tocopherol (vitamin E) formulations often show poor intestinal absorption. Delivery of CoQ(10) and vitamin E was enhanced when used with a new formulation, NanoSolve (Lipoid GmbH, Ludwigshafen, Germany), as shown by an open, comparative monocenter, crossover study of 24 vo...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章,随机对照试验


    authors: Wajda R,Zirkel J,Schaffer T

    更新日期:2007-12-01 00:00:00

  • Systemic and Adipose Tissue Redox Status in Sprague-Dawley Rats Fed Normal- and High-Fat Diets Supplemented with Lycopene.

    abstract::Dietary patterns high in fat influence local and systemic oxidative stress through adipose tissue (AT) accrual and increased reactive oxygen species generation. Lycopene, a carotenoid with antioxidant functionality, may mitigate excess oxidative stress, yet the lipophilic nature of this compound may limit its function...

    journal_title:Journal of medicinal food

    pub_type: 杂志文章


    authors: Senkus KE,Tan L,Crowe-White KM

    更新日期:2020-07-15 00:00:00