Using the context preexposure facilitation effect to study long-term context memory in preweanling, juvenile, adolescent, and adult rats.

Abstract:

:The present study used the context preexposure facilitation effect (CPFE) to examine long-term retention of incidental context learning in periweanling, adolescent and adult rats. The CPFE is a variant of contextual fear conditioning in which encoding the context representation, associating this representation with shock, and expressing the context-shock association each occur on separate occasions. Experiment 1 manipulated the retention interval-1d, 8d, 15d, or 22d-between context preexposure and training with immediate shock to determine how long the encoded context could be remembered (testing always occurred 24h following training). The other factors were age-postnatal day (PND) 24 vs 31-and training group-Preexposed to the training context (Pre) vs. an alternate context (Alt-Pre). At both ages, significantly more freezing was evident in the Pre vs. Alt Pre Groups at the 24h, 8d and 15d retention intervals but not at the 22d interval, indicating that juvenile-adolescent rats remember the context for up to 15d. In contrast, context memory persists for 22days in adult rats (Experiment 2); and is not evident after 24h, 8d, or 15d retention intervals in PND 17 rats (Experiment 3). The present study illustrates the value of the CPFE paradigm for investigations of long-term context memory in developing rats. Implications for the neurobiology of infantile amnesia are discussed.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Robinson-Drummer PA,Stanton ME

doi

10.1016/j.physbeh.2014.12.033

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

22-8

eissn

0031-9384

issn

1873-507X

pii

S0031-9384(14)00657-X

journal_volume

148

pub_type

杂志文章
  • Effects of prenatal testosterone propionate treatment on saccharin preference of adult rats exposed to ethanol in utero.

    abstract::Prenatal exposure to alcohol feminizes saccharin consumption patterns in adult male rats. To study the involvement of testosterone in this effect, testosterone propionate (TP) was administered to pregnant dams in an attempt to reverse that feminized saccharin consumption pattern in the male offspring. Female offspring...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(87)90016-3

    authors: McGivern RF,Holcomb C,Poland RE

    更新日期:1987-01-01 00:00:00

  • Antipsychotic drug and body weight set-point.

    abstract:OBJECTIVE:Antipsychotic (AP) drugs frequently induce weight gain. The present study aimed at exploring a potential association between antipsychotic-induced weight gain and delayed negative alliesthesia for sweet stimuli. RESEARCH METHODS AND PROCEDURES:The study aimed at recruiting patients undergoing AP treatment, h...

    journal_title:Physiology & behavior

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.physbeh.2008.05.013

    authors: Khazaal Y,Chatton A,Claeys F,Ribordy F,Zullino D,Cabanac M

    更新日期:2008-09-03 00:00:00

  • Angiotensin II (de)sensitization: Fluid intake studies with implications for cardiovascular control.

    abstract::Cardiovascular disease is the leading cause of death worldwide and hypertension is the most common risk factor for death. Although many anti-hypertensive pharmacotherapies are approved for use in the United States, rates of hypertension have increased over the past decade. This review article summarizes a presentation...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2016.01.020

    authors: Daniels D

    更新日期:2016-08-01 00:00:00

  • The effect of social environment on the immune response of female common voles in matriarchal laboratory groups.

    abstract::We used the hemagglutination test to investigate differences in the specific immune response to sheep red blood cells (SRBC) of female common voles living in matriarchal groups. The applied test proved to be a useful tool for studying the effect of the social environment on the immune response in small mammals. The re...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(00)00332-2

    authors: Heise SR,Van Acker A

    更新日期:2000-11-01 00:00:00

  • Behavioral responses of CD-1 mice to conspecific and heterospecific blood odors and to a blood odor component.

    abstract::The odor of blood may have both aversive and attractive properties for mammals, depending on the species of the odor donor and the species perceiving the odor. To better understand the informational content of blood odor for a prey species we assessed behavioral responses of male CD-1 mice (n=60) to the odor of blood ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2017.12.006

    authors: Lahger C,Laska M

    更新日期:2018-02-01 00:00:00

  • Ileal brake: a sensible food target for appetite control. A review.

    abstract::With the rising prevalence of obesity and related health problems increases, there is increased interest in the gastrointestinal system as a possible target for pharmacological or food-based approaches to weight management. Recent studies have shown that under normal physiological situations undigested nutrients can r...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2008.07.018

    authors: Maljaars PW,Peters HP,Mela DJ,Masclee AA

    更新日期:2008-10-20 00:00:00

  • The effect of cocaine on rotarod performance in male C57BL/6J mice.

    abstract::There is surprisingly little research examining the effect of cocaine on motor learning. Given that changes in motor activity can confound behavioral assays of learning and memory a direct assessment of cocaine on motor learning seems warranted. The present study was conducted to examine the effect of cocaine on motor...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2013.05.027

    authors: Heyser CJ,Vishnevetsky D,Berten S

    更新日期:2013-06-13 00:00:00

  • Diet self-selection and food hoarding after food deprivation by Siberian hamsters.

    abstract::Siberian hamsters (Phodopus sungorus) increase food hoarding, but not food intake, after a fast. Because the physiological mechanisms underlying these changes in food hoarding are virtually unknown, we sought insight into these mechanisms by allowing hamsters to self-select their diet from food sources varying in macr...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00167-5

    authors: Day DE,Mintz EM,Bartness TJ

    更新日期:1999-12-01 00:00:00

  • Fatty acid responses in taste cells from obesity-prone and -resistant rats.

    abstract::One of the transduction mechanisms for the chemoreception of fat has been proposed to involve the inhibition of delayed rectifying potassium (DRK) channels by polyunsaturated free fatty acids (PUFAs). In the present study we have compared the responsiveness of fungiform taste receptor cells (TRCs) to fatty acids in ob...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2005.08.057

    authors: Gilbertson TA,Liu L,Kim I,Burks CA,Hansen DR

    更新日期:2005-12-15 00:00:00

  • An activity indicator of acute withdrawal depends on amphetamine dose in rats.

    abstract::A moderate dose of amphetamine (AMPH) produces hypoactivity around 20 h post-administration. This hypoactivity may be an indicator of an acute withdrawal state. The purpose was to see how AMPH doses affected the expression of this hypoactivity and, by inference, AMPH-induced acute withdrawal. Rats were housed in indiv...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2005.10.009

    authors: White W,White IM

    更新日期:2006-02-28 00:00:00

  • Responsiveness of dog thalamic neurons to taste stimulation of various tongue regions.

    abstract::Receptive fields of single thalamic taste neurons in dogs were studied by examining responses to stimuli representing the four basic taste qualities applied to five different regions on the tongue surface. Twenty single thalamic units responded to taste stimulation of the tongue ipsilateral to the recording site were ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(82)90249-9

    authors: Ninomiya Y,Funakoshi M

    更新日期:1982-10-01 00:00:00

  • Effect of intracerebroventricular administration of vasopressin on stress-induced hyperthermia in rats.

    abstract::Vasopressin has been reported to be an endogenous antipyretic peptide. The present study assessed whether this peptide has similar effects on stress-induced hyperthermia. Infusion of 3 ng of vasopressin into the lateral ventricle prior to a 40-min restraint stress reduced significantly the hyperthermic response of rat...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:

    authors: Terlouw EM,Kent S,Cremona S,Dantzer R

    更新日期:1996-08-01 00:00:00

  • Overlapping litters and reproductive performance in the domestic rabbit.

    abstract::Rabbits (Oryctolagus cuniculus), like many small mammals, have a marked postpartum estrus, and during the breeding season, are often both pregnant and lactating. We examined reproductive performance and allocation of resources by rabbit mothers with overlapping litters under presumably optimal conditions of unrestrict...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2004.05.011

    authors: Martínez-Gómez M,Juárez M,Distel H,Hudson R

    更新日期:2004-09-30 00:00:00

  • Acute and conditioned blood pressure changes in relation to social and psychosocial stimuli in rats.

    abstract::The naturally occurring tendency to compete with other rats for territorial space has been used to study individual behavior characteristics and blood pressure reactivity to social stimuli in adult male TMD-S3 rats. The competitive characteristics of the individual rats are consistent in two different social situation...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(85)90073-3

    authors: Fokkema DS,Koolhaas JM

    更新日期:1985-01-01 00:00:00

  • Viewing and sectioning the rat's optic nerve using cheap retractors.

    abstract::A technique for sectioning the optic nerve in rats is described which permits direct viewing of the nerve during surgery. The technique results in no damage to the front of the eye. A procedure for constructing cheap, effective retractors is described. ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(76)90026-3

    authors: Asdourian D,Chiodo LA,Dark JG

    更新日期:1976-12-01 00:00:00

  • A new neurometric dissection of the area-under-curve-associated jiggle of the motor evoked potential induced by transcranial magnetic stimulation.

    abstract:OBJECTIVE:The jiggle of the motor evoked potential (MEP) induced by transcranial magnetic stimulation (TMS) depends on a number of factors including the assessment of this stochastic signal by the method known as area under curve (AUC). We aim to ascertain the MEP findings assessed by the AUC method obtained from indiv...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2015.01.014

    authors: Leon-Sarmiento FE,Rizzo-Sierra CV,Leon-Ariza JS,Leon-Ariza DS,Sobota R,Prada DG

    更新日期:2015-03-15 00:00:00

  • Exposure to PCB 77 affects the maternal behavior of rats.

    abstract::Polychlorinated biphenyls are environmental contaminants known to affect neurobehavioral development in many laboratory studies using different animal models. Because of their bioaccumulation and long half-life they are a serious concern for our own species. The dioxin-like PCB congener 3,4,3',4'-tetrachlorobiphenyl (...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2004.10.022

    authors: Simmons SL,Cummings JA,Clemens LG,Nunez AA

    更新日期:2005-01-31 00:00:00

  • A positioning fixture for L-shaped rotating undercutting microknives.

    abstract::A simple, inexpensive device which controls the insertion, positioning and withdrawal of cortical undercutting microkinives is described. The device aids the "rolling" insertion of an L-shaped microknife which produces a minimum amount of overlying tissue damage while it holds the knife steady during undercutting and ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(83)80010-9

    authors: Kubos KL,Kummel J,Moran TH,Sanberg PR,Bolduc PL,Robinson RG

    更新日期:1983-11-01 00:00:00

  • Effect of acute caffeine intake on hit accuracy and reaction time in professional e-sports players.

    abstract::Caffeine is considered a cognitive enhancer at low to moderate doses because it improves alertness, vigilance, attention, and reaction time. However, no previous investigation has assessed the effect of acute caffeine intake on e-sports-specific performance. The aim of this investigation was to determine the effect of...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2020.113031

    authors: Sainz I,Collado-Mateo D,Coso JD

    更新日期:2020-10-01 00:00:00

  • Influence of olfactory stimulation on nociceptive behavior in mice.

    abstract::The reactions elicited by nociceptive stimulations were studied in mice exposed to the presence of different odors: positive (attractive), negative (aversive), or neutral. In a first set of experiments, the animals were not habituated to the odors before the nociceptive stimuli were applied; in this case, the olfactor...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(97)00024-3

    authors: Jahangeer AC,Mellier D,Caston J

    更新日期:1997-08-01 00:00:00

  • Sexual experience blocks the ability of clitoral stimulation to induce a conditioned place preference in the rat.

    abstract::We have previously established the rewarding value of clitoral stimulation (CLS) through the demonstration that manual, distributed, CLS induces a significant conditioned place preference (CPP) and conditioned partner preference in naïve, hormonally primed and non-hormonally primed rats. The present experiment asks wh...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2013.06.005

    authors: Parada M,Jafari N,Pfaus JG

    更新日期:2013-07-02 00:00:00

  • Photoperiod and body weight in female Syrian hamsters: skeleton photoperiods, response magnitude, and development of photorefractoriness.

    abstract::Two experiments examined the effects of various photoperiods on body weight and reproductive function in Syrian hamsters (Mesocricetus auratus). In Experiment 1 female hamsters were exposed to symmetrical skeleton photoperiods in which dawn and dusk were mimicked by 1-hr light pulses. A skeleton long (LD 16:8) photope...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:

    authors: Wade GN,Bartness TJ,Alexander JR

    更新日期:1986-01-01 00:00:00

  • Dietary interventions for autism spectrum disorder: New perspectives from the gut-brain axis.

    abstract::There is still controversy surrounding the effectiveness of dietary interventions for autism spectrum disorder (ASD), namely the gluten-free/casein free diet and the ketogenic diet. Additionally, as studies mainly investigated their impact on ASD symptoms and behaviors, much remains unknown about their mechanisms of a...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2018.07.014

    authors: Doenyas C

    更新日期:2018-10-01 00:00:00

  • Effects of wheel running on food intake and weight gain of male and female rats.

    abstract::Adult male and female rats were housed in a sedentary condition or given free access to a running wheel for 50 days. Running wheel activity of female rats was higher than that of males throughout the experiment. Food intake, of both male and female rats that could take exercise increased, and the rate of increase of f...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(82)90211-6

    authors: Tokuyama K,Saito M,Okuda H

    更新日期:1982-05-01 00:00:00

  • Aversion induced by electrical stimulation of the mesencephalic locomotor region in the intact and freely moving rat.

    abstract::Electrical stimulation of the so-called "mesencephalic locomotor region" (MLR) in the acute mesencephalic and restrained rat is known to induce locomotion. In the intact and freely moving rat, electrical stimulation of an area coextensive with MLR is reported to elicit an apparently aversive type of behavioral respons...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90127-p

    authors: Depoortere R,Sandner G,Di Scala G

    更新日期:1990-03-01 00:00:00

  • Blood glucose levels in portal and peripheral circulation and their relation to food intake in the rat.

    abstract::Rats weighing about 450 g were provided with permanent catheters in the portal vein and the right auricle. This method allows blood sampling from the portal and peripheral circulation at the same moment in the nondisturbed unanesthetized rat. In the ad lib condition the portal glucose level was higher than that in the...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(77)90342-0

    authors: Strubbe JH,Steffens AB

    更新日期:1977-08-01 00:00:00

  • Autism: a large unmet medical need and a complex research problem.

    abstract::Autism has been becoming the focus of attention as its apparently increasing prevalence is better appreciated. According to some estimates, the frequency of children with autistic spectrum disorder (ASD) can be as high as 1 in 150. The diagnosis can be made as early as 2 years of age, and autistic patients often have ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/s0031-9384(03)00165-3

    authors: Gerlai J,Gerlai R

    更新日期:2003-08-01 00:00:00

  • Associations between Otitis media, taste sensitivity and adiposity: Two studies across childhood.

    abstract:BACKGROUND:Otitis media (OM), or middle ear infections, are one of the most common diseases during early childhood. OM has been linked to changes in food preferences through potential effects on taste signalling, and thereby, to increased weight. OBJECTIVES:We investigated the associations between OM, taste sensitivit...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.112570

    authors: Fogel A,Blissett J

    更新日期:2019-09-01 00:00:00

  • Effect of sucrose in breakfast items on pleasantness and food intake in the elderly.

    abstract::This study was designed to determine the differences between young and elderly people on the perceived intensity and pleasantness of sucrose in foods, in relation to their food intake. First, a group of 35 young subjects (mean age: 22 +/- 2 years) and 29 elderly subjects (mean age: 79 +/- 6 years) judged the intensity...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(96)00306-x

    authors: De Jong N,De Graaf C,Van Staveren WA

    更新日期:1996-12-01 00:00:00

  • Glucose tolerance in fish: Is the daily feeding time important?

    abstract::Daily rhythms in glucose tolerance have been reported for several species of mammals, which seem to be linked to factors such as daily rhythms of insulin resistance and feeding habits. In this paper, we studied entrainment to a daily scheduled meal of blood glucose after carbohydrate intake (dextrin or glucose). After...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2008.12.015

    authors: López-Olmeda JF,Egea-Alvarez M,Sánchez-Vázquez FJ

    更新日期:2009-03-23 00:00:00