Fat-suppressed alternating-SSFP for whole-brain fMRI using breath-hold and visual stimulus paradigms.

Abstract:

PURPOSE:To achieve artifact-suppressed whole-brain pass-band-balanced steady-state free precession functional MRI from a single functional magnetic resonance imaging (fMRI) scan. METHODS:A complete and practical data acquisition sequence for alt-SSFP fMRI was developed. First, multishot flyback-echo-planar imaging (EPI) and echo-time shifting were used to achieve data acquisition that was robust against eddy currents, gradient delays, and ghosting artifacts. Second, a steady-state catalyzation scheme was implemented to reduce oscillations in the transient signal when catalyzing in and out of alternate steady states. Next, a short spatial-spectral radiofrequency (RF) pulse was designed to achieve excellent fat-suppression while maintaining a repetition time <15 ms to sensitize functional activation toward smaller vessels and capillaries. Lastly, parallel imaging was used to achieve whole-brain coverage and sufficiently high temporal resolution. RESULTS:Breath-hold experiments showed excellent fat-suppression and alt-SSFP's capability to recover functional sensitivity from signal dropout regions of conventional gradient-echo and banding artifacts from conventional pass-band-balanced steady-state free precession. Applying fat-suppression resulted in improved activation maps and increased temporal SNR. Visual stimulus functional studies verify the proposed method's excellent functional sensitivity to neuronal activation. CONCLUSION:Artifact-suppressed images are demonstrated, showing a practical pass-band-balanced steady-state free precession fMRI method that permits whole-brain imaging with excellent blood oxygen level-dependent sensitivity and fat suppression.

journal_name

Magn Reson Med

authors

Jou T,Patterson S,Pauly JM,Bowen CV

doi

10.1002/mrm.25797

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

1978-88

issue

5

eissn

0740-3194

issn

1522-2594

journal_volume

75

pub_type

杂志文章
  • Prospective GIRF-based RF phase cycling to reduce eddy current-induced steady-state disruption in bSSFP imaging.

    abstract:PURPOSE:To propose an explicit Balanced steady-state free precession (bSSFP) signal model that predicts eddy current-induced steady-state disruptions and to provide a prospective, practical, and general eddy current compensation method. THEORY AND METHODS:Gradient impulse response functions (GIRF) were used to simulat...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28097

    authors: Bruijnen T,Stemkens B,van den Berg CAT,Tijssen RHN

    更新日期:2020-07-01 00:00:00

  • Rigid-body motion correction with self-navigation MRI.

    abstract::The use of phase correlation to detect rigid-body translational motion is reviewed and applied to individual echotrains in turbo-spin-echo data acquisition. It is shown that when the same echotrain is acquired twice, the subsampled correlation provides an array of delta-functions, from which the motion that occurred b...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21883

    authors: Mendes J,Kholmovski E,Parker DL

    更新日期:2009-03-01 00:00:00

  • Spiral trajectory design: a flexible numerical algorithm and base analytical equations.

    abstract:PURPOSE:Spiral-based trajectories for magnetic resonance imaging can be advantageous, but are often cumbersome to design or create. This work presents a flexible numerical algorithm for designing trajectories based on explicit definition of radial undersampling, and also gives several analytical expressions for charact...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24675

    authors: Pipe JG,Zwart NR

    更新日期:2014-01-01 00:00:00

  • Fast model-based T2 mapping using SAR-reduced simultaneous multislice excitation.

    abstract:PURPOSE:To obtain whole-brain high-resolution T2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. METHODS:A multi-echo spin-echo sequence was modified to acquire multiple s...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27890

    authors: Hilbert T,Schulz J,Marques JP,Thiran JP,Krueger G,Norris DG,Kober T

    更新日期:2019-12-01 00:00:00

  • Comparison between simulated decoupling regimes for specific absorption rate prediction in parallel transmit MRI.

    abstract:PURPOSE:The use of electromagnetic (EM) modeling is critical for specific absorption rate (SAR) characterization in parallel transmission MRI. Radiofrequency arrays that include decoupling networks can be difficult to characterize accurately in simulation. A practical method of simplifying modeling is to exclude the de...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25504

    authors: Beqiri A,Hand JW,Hajnal JV,Malik SJ

    更新日期:2015-11-01 00:00:00

  • Fast anatomical imaging of the heart and assessment of myocardial perfusion with arrhythmia insensitive magnetization preparation.

    abstract::A new contrast preparation based on modified driven equilibrium Fourier transfer is introduced and evaluated for generation of T1-weighted images for assessment of the myocardial perfusion with contrast agent first-pass kinetics. The new preparation scheme produces T1 contrast with insensitivity to arrhythmias in pros...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910340408

    authors: Tsekos NV,Zhang Y,Merkle H,Wilke N,Jerosch-Herold M,Stillman A,Uğurbil K

    更新日期:1995-10-01 00:00:00

  • Tilt optimized flip uniformity (TOFU) RF pulse for uniform image contrast at low specific absorption rate levels in combination with a surface breast coil at 7 Tesla.

    abstract:PURPOSE:Going to ultrahigh field MRI (e.g., 7 Tesla [T]), the nonuniformity of the B1+ field and the increased radiofrequency (RF) power deposition become challenging. While surface coils improve the power efficiency in B1+, its field remains nonuniform. In this work, an RF pulse was designed that uses the slab selecti...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25415

    authors: van Kalleveen IM,Boer VO,Luijten PR,Klomp DW

    更新日期:2015-08-01 00:00:00

  • Determining the extent to which delayed-enhancement images reflect the partition-coefficient of Gd-DTPA in canine studies of reperfused and unreperfused myocardial infarction.

    abstract::MRI after a constant infusion (CI) of Gd-DTPA has been used to identify the extent of myocardial infarction (MI). However, Gd-DTPA-enhanced "viability" imaging is more commonly performed with a bolus (for "delayed-enhancement" (DE) imaging). This study sought to determine how image delay time and time postinfarction i...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20236

    authors: Thornhill RE,Prato FS,Wisenberg G,Moran GR,Sykes J

    更新日期:2004-11-01 00:00:00

  • High-resolution quantitative sodium imaging at 9.4 Tesla.

    abstract:PURPOSE:Investigation of the feasibility to perform high-resolution quantitative sodium imaging at 9.4 Tesla (T). METHODS:A proton patch antenna was combined with a sodium birdcage coil to provide a proton signal without compromising the efficiency of the X-nucleus coil. Sodium density weighted images with a nominal r...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25096

    authors: Mirkes CC,Hoffmann J,Shajan G,Pohmann R,Scheffler K

    更新日期:2015-01-01 00:00:00

  • Robust diffusion tensor imaging by spatiotemporal encoding: Principles and in vivo demonstrations.

    abstract:PURPOSE:Evaluate the usefulness of single-shot and of interleaved spatiotemporally encoded (SPEN) methods to perform diffusion tensor imaging (DTI) under various preclinical and clinical settings. METHODS:A formalism for analyzing SPEN DTI data is presented, tailored to account for the spatially dependent b-matrix wei...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26197

    authors: Solomon E,Liberman G,Nissan N,Frydman L

    更新日期:2017-03-01 00:00:00

  • Template-based field map prediction for rapid whole brain B0 shimming.

    abstract:PURPOSE:In typical MRI protocols, time is spent acquiring a field map to calculate the shim settings for best image quality. We propose a fast template-based field map prediction method that yields near-optimal shims without measuring the field. METHODS:The template-based prediction method uses prior knowledge of the ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27020

    authors: Shi Y,Vannesjo SJ,Miller KL,Clare S

    更新日期:2018-07-01 00:00:00

  • Characterization of perfluorocarbon relaxation times and their influence on the optimization of fluorine-19 MRI at 3 tesla.

    abstract:PURPOSE:To characterize and optimize 19 F MRI for different perfluorocarbons (PFCs) at 3T and quantify the loss of acquisition efficiency as a function of different temperature and cellular conditions. METHODS:The T1 and T2 relaxation times of the commonly used PFCs perfluoropolyether (PFPE), perfluoro-15-crown-5-ethe...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26317

    authors: Colotti R,Bastiaansen JAM,Wilson A,Flögel U,Gonzales C,Schwitter J,Stuber M,van Heeswijk RB

    更新日期:2017-06-01 00:00:00

  • PRESTO-SENSE: an ultrafast whole-brain fMRI technique.

    abstract::A new ultrafast MR imaging method is proposed and tested, which enables whole-brain fMRI with a true temporal resolution of 1 sec. The method combines a 3D PRESTO pulse sequence with the concept of sensitivity-encoding with multiple receiver coils (SENSE). The so-called PRESTO-SENSE technique is demonstrated on a set ...

    journal_title:Magnetic resonance in medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/1522-2594(200006)43:6<779::aid-mrm1>3.0.co

    authors: Golay X,Pruessmann KP,Weiger M,Crelier GR,Folkers PJ,Kollias SS,Boesiger P

    更新日期:2000-06-01 00:00:00

  • Direct projective time-of-flight NMR angiography within 4s.

    abstract::To enhance contrast between flow and static tissue, NMR projective angiographic methods usually require data subtraction, or alternatively the application of special data processing routines such as the "maximum intensity projection" algorithm. We have successfully developed a direct projection method which yields suf...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910180213

    authors: Matsuda T,Doyle M,Pohost GM

    更新日期:1991-04-01 00:00:00

  • Quantitative magnetization transfer imaging in human brain at 3 T via selective inversion recovery.

    abstract::Quantitative magnetization transfer imaging yields indices describing the interactions between free water protons and immobile, macromolecular protons-including the macromolecular to free pool size ratio (PSR) and the rate of magnetization transfer between pools k(mf) . This study describes the first implementation of...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22928

    authors: Dortch RD,Li K,Gochberg DF,Welch EB,Dula AN,Tamhane AA,Gore JC,Smith SA

    更新日期:2011-11-01 00:00:00

  • Flow-suppressed hyperpolarized 13 C chemical shift imaging using velocity-optimized bipolar gradient in mouse liver tumors at 9.4 T.

    abstract:PURPOSE:To optimize and investigate the influence of bipolar gradients for flow suppression in metabolic quantification of hyperpolarized 13 C chemical shift imaging (CSI) of mouse liver at 9.4 T. METHODS:The trade-off between the amount of flow suppression using bipolar gradients and T2* effect from static spins was ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26578

    authors: Lee H,Lee J,Joe E,Yang S,Song JE,Choi YS,Wang E,Joo CG,Song HT,Kim DH

    更新日期:2017-11-01 00:00:00

  • Black-blood native T1 mapping: Blood signal suppression for reduced partial voluming in the myocardium.

    abstract:PURPOSE:To study the feasibility of black-blood contrast in native T1 mapping for reduction of partial voluming at the blood-myocardium interface. METHODS:A saturation pulse prepared heart-rate-independent inversion recovery (SAPPHIRE) T1 mapping sequence was combined with motion-sensitized driven-equilibrium (MSDE) b...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26378

    authors: Weingärtner S,Meßner NM,Zöllner FG,Akçakaya M,Schad LR

    更新日期:2017-08-01 00:00:00

  • Manganese-enhanced magnetic resonance imaging for in vivo assessment of damage and functional improvement following spinal cord injury in mice.

    abstract::In past decades, much effort has been invested in developing therapies for spinal injuries. Lack of standardization of clinical read-out measures, however, makes direct comparison of experimental therapies difficult. Damage and therapeutic effects in vivo are routinely evaluated using rather subjective behavioral test...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20888

    authors: Stieltjes B,Klussmann S,Bock M,Umathum R,Mangalathu J,Letellier E,Rittgen W,Edler L,Krammer PH,Kauczor HU,Martin-Villalba A,Essig M

    更新日期:2006-05-01 00:00:00

  • T2 relaxation-time mapping in healthy and diseased skeletal muscle using extended phase graph algorithms.

    abstract:PURPOSE:Multi-echo spin-echo (MSE) transverse relaxometry mapping using multi-component models is used to study disease activity in neuromuscular disease by assessing the T2 of the myocytic component (T2water ). Current extended phase graph algorithms are not optimized for fat fractions above 50% and the effects of ina...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28290

    authors: Keene KR,Beenakker JM,Hooijmans MT,Naarding KJ,Niks EH,Otto LAM,van der Pol WL,Tannemaat MR,Kan HE,Froeling M

    更新日期:2020-11-01 00:00:00

  • Removal of nuisance signals from limited and sparse 1H MRSI data using a union-of-subspaces model.

    abstract:PURPOSE:To remove nuisance signals (e.g., water and lipid signals) for (1) H MRSI data collected from the brain with limited and/or sparse (k, t)-space coverage. METHODS:A union-of-subspace model is proposed for removing nuisance signals. The model exploits the partial separability of both the nuisance signals and the...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25635

    authors: Ma C,Lam F,Johnson CL,Liang ZP

    更新日期:2016-02-01 00:00:00

  • Multiclass imbalance learning: Improving classification of pediatric brain tumors from magnetic resonance spectroscopy.

    abstract:PURPOSE:Classification of pediatric brain tumors from 1 H-magnetic resonance spectroscopy (MRS) can aid diagnosis and management of brain tumors. However, varied incidence of the different tumor types leads to imbalanced class sizes and introduces difficulties in classifying rare tumor groups. This study assessed diffe...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26318

    authors: Zarinabad N,Wilson M,Gill SK,Manias KA,Davies NP,Peet AC

    更新日期:2017-06-01 00:00:00

  • Comprehensive approach for correction of motion and distortion in diffusion-weighted MRI.

    abstract::Patient motion and image distortion induced by eddy currents cause artifacts in maps of diffusion parameters computed from diffusion-weighted (DW) images. A novel and comprehensive approach to correct for spatial misalignment of DW imaging (DWI) volumes acquired with different strengths and orientations of the diffusi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10677

    authors: Rohde GK,Barnett AS,Basser PJ,Marenco S,Pierpaoli C

    更新日期:2004-01-01 00:00:00

  • High-resolution 1 H-MRSI of the brain using short-TE SPICE.

    abstract:PURPOSE:To improve signal-to-noise ratio (SNR) for high-resolution spectroscopic imaging using a subspace-based technique known as SPectroscopic Imaging by exploiting spatiospectral CorrElation (SPICE). METHODS:The proposed method is based on a union-of-subspaces model of MRSI signals, which exploits the partial separ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26130

    authors: Ma C,Lam F,Ning Q,Johnson CL,Liang ZP

    更新日期:2017-02-01 00:00:00

  • Fat-water separation based on Transition REgion Extraction (TREE).

    abstract:PURPOSE:To develop a method based on fat-water transition region extraction (TREE) for robust fat-water separation and quantification in challenging scenarios, including low signal-to-noise ratio (SNR), fast changing B0 field, and disjointed anatomies. THEORY AND METHODS:In TREE method, the phasor solutions of each pi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27710

    authors: Peng H,Zou C,Cheng C,Tie C,Qiao Y,Wan Q,Lv J,He Q,Liang D,Liu X,Liu W,Zheng H

    更新日期:2019-07-01 00:00:00

  • Precise relaxation time measurements of normal-appearing white matter in inflammatory central nervous system disease.

    abstract::Precise relaxation time (RT) measurements have been made, with a standard deviation of 3% for T1 and T2 in white matter in normal volunteers. This sets an upper limit to the instrumental random errors (imprecision). Achieving this precision requires careful adjustment and use of the imager. The wide variation in RTs s...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910110307

    authors: Miller DH,Johnson G,Tofts PS,MacManus D,McDonald WI

    更新日期:1989-09-01 00:00:00

  • Effect of distortion corrections on the tractography quality in spinal cord diffusion-weighted imaging.

    abstract:PURPOSE:To assess the impact of a different distortion correction (DC) method and patient geometry (sagittal balance) on the quality of spinal cord tractography rendering according to different tractography approaches. METHODS:Forty-four adults free of spinal cord diseases underwent cervical diffusion-weighted imaging...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28665

    authors: Dauleac C,Bannier E,Cotton F,Frindel C

    更新日期:2021-01-21 00:00:00

  • Evaluation of wave delivery methodology for brain MRE: Insights from computational simulations.

    abstract:PURPOSE:MR elastography (MRE) of the brain is being explored as a biomarker of neurodegenerative disease such as dementia. However, MRE measures for healthy brain have varied widely. Differing wave delivery methodologies may have influenced this, hence finite element-based simulations were performed to explore this pos...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26333

    authors: McGrath DM,Ravikumar N,Beltrachini L,Wilkinson ID,Frangi AF,Taylor ZA

    更新日期:2017-07-01 00:00:00

  • Accelerated MR parameter mapping with low-rank and sparsity constraints.

    abstract:PURPOSE:To enable accurate magnetic resonance (MR) parameter mapping with accelerated data acquisition, utilizing recent advances in constrained imaging with sparse sampling. THEORY AND METHODS:A new constrained reconstruction method based on low-rank and sparsity constraints is proposed to accelerate MR parameter map...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25421

    authors: Zhao B,Lu W,Hitchens TK,Lam F,Ho C,Liang ZP

    更新日期:2015-08-01 00:00:00

  • Simplified synthesis and relaxometry of magnetoferritin for magnetic resonance imaging.

    abstract::Magnetoferritin nanoparticles have been developed as high-relaxivity, functional contrast agents for MRI. Several previous techniques have relied on unloading native ferritin and re-incorporation of iron into the core, often resulting in a polydisperse sample. Here, a simplified technique is developed using commercial...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22526

    authors: Jordan VC,Caplan MR,Bennett KM

    更新日期:2010-11-01 00:00:00

  • Generalization of intravoxel incoherent motion model by introducing the notion of continuous pseudodiffusion variable.

    abstract:PURPOSE:A generalized intravoxel incoherent motion (IVIM) model, called the GIVIM, was proposed to better account for complex perfusion present in the tissues having various vessels and flow regimes, such as the liver. THEORY AND METHODS:The notions of continuous pseudodiffusion variable as well as perfusion fraction ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26064

    authors: Kuai ZX,Liu WY,Zhang YL,Zhu YM

    更新日期:2016-11-01 00:00:00