Abstract：
OBJECTIVE:Oxidative metabolism is impaired in several medical conditions including psychiatric disorders, and this imbalance may be involved in the etiology of these diseases. The present study evaluated oxidative balance in pediatric and adolescent patients with attention deficit hyperactivity disorder (ADHD). METHODS:The study included 48 children and adolescents (34 male, 14 female) with ADHD who had no neurological, systemic, or comorbid psychiatric disorders, with the exception of oppositional defiant disorder (ODD), and 24 sex- and age-matched healthy controls (17 male and seven female). RESULTS:TAS was significantly lower, and TOS and OSI were significantly higher in patients with ADHD than in healthy controls. Total antioxidant levels were lower in patients with comorbid ODD than in those with no comorbidity. No difference was found in TOS or OSI among the ADHD subtypes; however, TAS was higher in the attention-deficient subtype. CONCLUSION:Our findings demonstrated that oxidative balance is impaired and oxidative stress is increased in children and adolescents with ADHD. This results are consistent with those of previous studies.
journal_name
Psychiatry Investigjournal_title
Psychiatry investigationauthors
Kul M,Unal F,Kandemir H,Sarkarati B,Kilinc K,Kandemir SBdoi
10.4306/pi.2015.12.3.361subject
Has Abstractpub_date
2015-07-01 00:00:00pages
361-6issue
3eissn
1738-3684issn
1976-3026journal_volume
12pub_type
杂志文章abstract：OBJECTIVE:For the proper treatment of first-episode psychosis, assessment of treatment response, remission, relapse, and recovery is important. Therefore, the present study aimed to develop operational definitions of clinical outcomes in first-episode psychosis. METHODS:A questionnaire was developed by a panel of expe...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2019.0240
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVE:Electrophysiological studies, which are mostly focused on afferent pathway, have proven that auditory processing deficits exist in patients with schizophrenia. Nevertheless, reports on the suppressive effect of efferent auditory pathway on cochlear outer hair cells among schizophrenia patients are limited. Th...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2016.13.1.82
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:Intolerance of uncertainty (IU) is a transdiagnostic construct in various anxiety and depressive disorders. However, the relationship between IU and panic symptom severity is not yet fully understood. We examined the relationship between IU, panic, and depressive symptoms during mindfulness-based cognitive th...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2016.13.2.196
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:Associations of thyroid dysfunction with cognitive impairment and depression in late-life have been described but remain controversial. This study aimed to investigate the associations of serum thyroid stimulating hormone (TSH) levels with cognitive impairment and depression after controlling for potential co...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2010.7.4.264
更新日期：2010-12-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to identify patterns of brain activation elicited by erotic visual stimuli in patients treated with either Selective Serotonin Reuptake Inhibitors (SSRIs) or mirtazipine. METHODS:Nine middle-aged men with major depressive disorder treated with an SSRI and ten middle-aged men w...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2009.6.2.85
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVE:Suicide is a leading cause of death in college age students. Identification of the associated risk factors has important implications for how to prevent and respond to this population; however, few studies have been performed on this topic in this age group. The purpose of this study was to evaluate the preva...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2008.5.2.86
更新日期：2008-06-01 00:00:00
abstract：:I report here an elderly woman receiving perphenazine together with terbinafine. After 1 week of terbinafine treatment she experienced extrapyramidal symptoms and, in particular, akathisia. Her symptoms did not disappear for 6 weeks, and so at 2 weeks prior to this most recent admission she had stopped taking terbinaf...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2012.9.4.422
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:This study aimed to investigate the adolescent brain activation patterns in response to performance feedback (PF), social reward (SR) and monetary reward (MR) and their association with psychological factors. METHODS:Functional magnetic resonance imaging (fMRI) was performed while middle school boys (n=15) p...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2013.10.1.47
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:Although neuroimaging studies have shown volumetric reductions, such as the anterior cingulate, prefrontal cortices, and hippocampus in patients with major depressive disorder (MDD), few studies have investigated the volume of or shape alterations in the subcortical regions and the brainstem. We hypothesized ...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2020.0025
更新日期：2020-05-01 00:00:00
abstract：:Electroconvulsive therapy (ECT) is not currently used as a first-line treatment for obsessive-compulsive disorder (OCD). However, several related case reports have demonstrated that ECT seems to be effective for severe OCD, especially when first-line therapies have failed. In this study, we describe the courses, detai...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2014.11.2.210
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVE:Coping can be defined as the reactions to harm or distress individuals take to reduce stress. This study aimed to determine how an individual's temperament and character is correlated with the person's main coping method. METHODS:The Korean version of the Ways of Coping Questionnaire and Temperament and Char...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2019.0084
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to determine the dose-response relationship between physical activity and anxiety symptoms. METHODS:We included data of 124,434 participants who had comprehensive health-screening examinations from January 1st, 2012, to December 31st, 2016, in Kangbuk Samsung Hospital, Seoul and Suwo...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2019.0078
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:Personality is defined as the trait-like qualities of a person. However, it has been recently suggested that the state effect of a situation leads to changes in scores on personality assessments. We predicted that traumatic experiences would induce changes not only in personality scores but also in the factor...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2012.9.4.361
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:This article examined the psychometric properties of the Korean version of the Infant-Toddler Social and Emotional Assessment (K-ITSEA). METHODS:Translation and back-translation of the K-ITSEA were conducted after obtaining a permission. Two thousand two hundred thirty six Korean community infants (1,199 boy...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2018.02.25
更新日期：2018-05-01 00:00:00
abstract：Objective:Research has shown that intranasal oxytocin affects social cognition and behavior; however, its effects vary based on social context, individual characteristics and dose. The present study aimed to determine effective dose of oxytocin spray on emotion recognition in healthy Korean males. Methods:The study fo...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2018.02.19
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:Depression is a very common symptom in people with mild cognitive impairment (MCI), a preclinical stage of Alzheimer's disease (AD), and in those with clinically evident AD. Moreover, MCI individuals with depression show a higher conversion rate to clinical AD than those without depression. This study aimed t...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2010.7.3.208
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:This study aims to examine the parallel multiple mediators of depressive symptoms and sleep quality in the relations between stress and physical health-related quality of life (PHQOL)/mental health-related quality of life (MHQOL) among the women in late pregnancy. METHODS:Of 1120 pregnant women participated ...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2019.02.14
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVE:Previous studies have shown that there is a correlation between lipid levels and depressive mood, and that lipids could be useful biomarkers for depression. We conducted this study to clarify the association between lipid levels and depressive mood in adolescents, especially in community samples. METHODS:We ...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2019.03.24
更新日期：2019-10-01 00:00:00
abstract：:Despite the fact that the lifetime and yearly prevalence rates of mental illness continue rising, such diseases have only been acknowledged as involved in workplace health issue since the 2000s. Additionally, while the number of recognized cases of mental illnesses is rather low compared to their prevalence, they have...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2016.10.24
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVE:This study investigated the treatment response and cognitive enhancement effects of buspirone augmentation of escitalopram in patients with major depressive disorder (MDD), according to atypical feature subtypes of MDD. METHODS:An 8 week, randomized, parallel-controlled, open-label study was conducted. The C...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2020.0017
更新日期：2020-08-01 00:00:00
abstract：:Major depressive disorder is often resistant to antidepressant treatment. Repetitive transcranial magnetic stimulation (rTMS) has been used in treatment-resistant depression (TRD). Known adverse events of rTMS include transient headache, local pain, syncope, seizure induction, and hypomania induction. This report outl...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2016.13.4.468
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:Postoperative delirium (POD) is a highly prevalent complex neuropsychiatric syndrome in elderly patients. However, its pathophysiology is currently unknown. Early detection and prevention of POD is important; therefore, the aim of this study was to investigate the link between preoperative insulin growth fact...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2016.13.3.327
更新日期：2016-05-01 00:00:00
abstract：:While cognitive behavior therapy is considered to be the first-line therapy for adolescent depression, there are limited data on whether other psychotherapeutic techniques are also effective in treating adolescents with depression. This report suggests the potential application of eye movement desensitization and repr...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2008.5.1.60
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that negatively affects different areas of life. We aimed to evaluate the associations between the Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) and ADHD and to assess the effect of the BDNF polymorphism on th...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2016.13.5.518
更新日期：2016-09-01 00:00:00
abstract：:Suicide attempts at the Han river are rapidly increasing, which are 4.11 times from 2005 to 2015, whereas the rate of completed suicide in South Korea increased 1.07 times during the same period. However, few studies have been conducted on the issue because many suicide attempters were seriously injured after a fall i...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2017.14.6.904
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:Idiopathic Parkinson's disease (IPD) is a chronic progressive neurodegenerative movement disorder characterized by motor and non-motor symptoms that affects patients' quality of life and caregiver burden. The aim of our study was to assess the caregiver burden (CB) in early and late stages of disease and to s...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.30773/pi.2019.02.20
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to explore the prognostic values of biomarkers of neurodegeneration as measured by magnetic resonance imaging (MRI) and amyloid burden as measured by amyloid positron emission tomography (PET) in predicting conversion to Alzheimer's disease (AD) in patients with mild cognitive impair...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2017.14.2.205
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:The economic crisis and the implementation of austerity measures in Greece lead to significant socioeconomic changes. The effects of the crisis were mainly felt by the Greek population during the years 2011 and 2012. This study aimed to investigate the impact of Greece's economic crisis on the seasonality of ...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2017.14.1.16
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:To investigate the altitude, immigration and suicide rates association in Turkey. METHODS:Suicide and immigration rates of 81 provinces and their elevation data were obtained. RESULTS:There were not significant correlations between country elevation, immigration and mean suicide rate. CONCLUSION:The findin...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2013.10.1.89
更新日期：2013-03-01 00:00:00
abstract：Objective:The study investigated to compare health care utilization and expenditures between diabetic patients with and without depression in Taiwan. Methods:Health care utilization and expenditure among diabetic patients with and without depression disorder during 2000 and 2004 were examined using Taiwan's population...
journal_title：Psychiatry investigation
pub_type： 杂志文章
doi：10.4306/pi.2017.14.6.770
更新日期：2017-11-01 00:00:00
