Abstract:
OBJECTIVE:Associations of thyroid dysfunction with cognitive impairment and depression in late-life have been described but remain controversial. This study aimed to investigate the associations of serum thyroid stimulating hormone (TSH) levels with cognitive impairment and depression after controlling for potential confounding factors. METHODS:The sample consisted of 495 community residents aged 65 or over in whom serum TSH had been assayed. Cognitive impairment was defined using the Community Screening Interview for Dementia, and depression was diagnosed using the Geriatric Mental State schedule. Age, gender, education, smoking history, physical activity, blood pressure, diabetes, and serum total cholesterol and albumin were included as covariates. RESULTS:There was a significant association between lower (hyperthyroid) serum TSH levels (<0.5 mIU/L) and cognitive impairment after adjustment [odds ratio 7.12 (95% confidence interval 1.35-37.5)]. However, no association was found between TSH levels and depression. CONCLUSION:Based on TSH levels, hyperthyroidism but not hypothyroidism was associated with cognitive impairment in this sample, and we found no evidence for an association of either with depression.
journal_name
Psychiatry Investigjournal_title
Psychiatry investigationauthors
Kim JM,Stewart R,Kim SY,Bae KY,Yang SJ,Kim SW,Shin IS,Yoon JSdoi
10.4306/pi.2010.7.4.264subject
Has Abstractpub_date
2010-12-01 00:00:00pages
264-9issue
4eissn
1738-3684issn
1976-3026journal_volume
7pub_type
杂志文章abstract:OBJECTIVE:This study analyzed the symptom frequencies of 17-item Hamilton Depression Rating Scale (HDRS-17) to understand the characteristics of each item and to propose the possible symptoms clusters. METHODS:From psychiatric clinics of 18 Hospitals in Korea, 1,183 patients, diagnosed with major depressive disorder (...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2011.8.4.312
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:The current study aimed to examine whether specific features of psychomotor retardation (PMR) and cognitive functioning established different profiles in unipolar (UD) and bipolar depression (BD). METHODS:Two groups of age-matched patients with UD (n=54) and BD (n=20) completed the Montgomery-Asberg Depressi...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.0116
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:Idiopathic Parkinson's disease (IPD) is a chronic progressive neurodegenerative movement disorder characterized by motor and non-motor symptoms that affects patients' quality of life and caregiver burden. The aim of our study was to assess the caregiver burden (CB) in early and late stages of disease and to s...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.02.20
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:Although the executive function subtests of the Cambridge Neuropsychological Test Automated Battery (CANTAB) have been used to assess cognitive function in diverse psychiatric illnesses, few studies have verified the validity of this battery for Korean psychiatric patients. Therefore, this preliminary study e...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2014.11.4.394
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that negatively affects different areas of life. We aimed to evaluate the associations between the Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) and ADHD and to assess the effect of the BDNF polymorphism on th...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2016.13.5.518
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:This study investigated the impact of executive function on the performance of two different affective tasks, the Facial Affect Identification Task (FAIT) and the Iowa Gambling Task (IGT), in patients with schizophrenia. METHODS:Thirty-nine patients with schizophrenia and 33 healthy controls completed the FA...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2009.6.3.156
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:Intolerance of uncertainty (IU) is a transdiagnostic construct in various anxiety and depressive disorders. However, the relationship between IU and panic symptom severity is not yet fully understood. We examined the relationship between IU, panic, and depressive symptoms during mindfulness-based cognitive th...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2016.13.2.196
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To analyze the relationship between seizure threshold (ST) and psychotropic drugs in patients treated with ECT. METHODS:We examined clinical data from 43 patients. ST was titrated at each treatment session. We examined associations between ST and psychotropic drugs using multivariate correlation analyses. Da...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.5.647
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:Recently, an increasing number of Korean male conscripts have been retiring because of military maladjustment despite the presence of qualifying medical and psychological screening tests in the Korean army. These problems suggest the presence of a common personality problem. To further examine this possibilit...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2013.10.2.131
更新日期:2013-06-01 00:00:00
abstract::Differentiating early Alzheimer's disease (AD) from depression with cognitive impairment is challenging in the elderly. To develop a model for differentiating these two conditions using electroencephalography (EEG), we enrolled 11 patients with early probable AD and 11 age- and cognitive function-matched patients with...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.5.708
更新日期:2017-09-01 00:00:00
abstract::This study investigated the relationship of personality, depression, somatization, anxiety with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH). The LUTS/BPH patients were evaluated with the International Prostate Symptom Score (IPSS), 44-item Big Five Inventory (BFI), the Patient He...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.2.268
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The aims of current study were to determine whether childhood maltreatment contributes to the occurrence of major depressive disorder (MDD) with bipolarity or suicidality. METHODS:In total, 132 outpatients diagnosed with MDD between 2014 and 2015 on the medical records were included. The subjects were divide...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.2.136
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:This study was conducted at Hanawon-a government sponsored educational facility for the settlement of North Korean refugees during their initial phase in South Korea-in 2004 to explore their mental health status and traumatic experiences in North Korea and during their escape period. METHODS:A survey was con...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2008.5.4.213
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:Suicide is a leading cause of death in college age students. Identification of the associated risk factors has important implications for how to prevent and respond to this population; however, few studies have been performed on this topic in this age group. The purpose of this study was to evaluate the preva...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2008.5.2.86
更新日期:2008-06-01 00:00:00
abstract:Objective:The Delirium Motor Subtype Scale (DMSS) is a validated and reliable instrument developed from various methods previously used to assess delirium motor subtypes. It focuses on pure motor disturbances with a relative specificity for delirium. The aim of this study was to investigate the validity and reliability...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2018.15.1.6
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To examine the reliability and validity of the self-report Korean version of Strengths and Difficulties Questionnaire (SDQ-Kr) in the community sample. METHODS:The SDQ-Kr was administered to a large sample of school children and adolescents (n=2814) and youth attendees of a psychiatric clinic (n=385) aged 11...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.4.491
更新日期:2015-10-01 00:00:00
abstract: Objective:To identify attachment insecurity as an associative factor with unresolved psychological distress 1 year after surgery in the early breast cancer (BC) population. Methods:One-hundred fourteen participants completed the Hospital Anxiety and Depression Scale (HADS) and the Experiences in Close Relationship (E...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.06.07
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:We aimed to examine the reliability and validity of the Korean Altman Self-Rating Mania Scale (K-ASRM) in a large sample of Korean non-clinical undergraduates. METHODS:Participants (n=1,091) filled out the K-ASRM with other self-report questionnaires assessing bipolarity, mood symptoms and affect. Reliabilit...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.5.562
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:The present study aimed to identify risk factors for future SI and to predict individual-level risk for future or persistent SI among college students. METHODS:Mental health check-up data collected over 3 years were retrospectively analyzed. Students were categorized as suicidal ideators and non-ideators at ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.08.21.3
更新日期:2018-11-01 00:00:00
abstract::This current study's goal is to summarize the literature regarding Antenatal Depression (AD) in the East Asian countries of Taiwan, China (including Hong Kong and Macau), Japan, and Korea. The main search utilized a Pub med Chinese Electronic Periodical Service (CEPS) literature review using keywords 'AD', and 'Prenat...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2012.9.2.111
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:This article examined the psychometric properties of the Korean version of the Infant-Toddler Social and Emotional Assessment (K-ITSEA). METHODS:Translation and back-translation of the K-ITSEA were conducted after obtaining a permission. Two thousand two hundred thirty six Korean community infants (1,199 boy...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.02.25
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:Electrophysiological studies, which are mostly focused on afferent pathway, have proven that auditory processing deficits exist in patients with schizophrenia. Nevertheless, reports on the suppressive effect of efferent auditory pathway on cochlear outer hair cells among schizophrenia patients are limited. Th...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2016.13.1.82
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the associative role of depression and apolipoprotein E epsilon 4 allele (APOEε4) in subjective cognitive decline (SCD) and its progression to objective cognitive decline. METHODS:After literature search in electronic databases, studies were selected by following precise eligibility criteria. Met...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.0324
更新日期:2020-09-01 00:00:00
abstract::The REAP-AP study recruited 3,746 patients with schizophrenia, in March and April 2016, from 71 centers in 15 Asian countries/territories namely Bangladesh, China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Myanmar, Pakistan, Singapore, Sri Lanka, Taiwan, Thailand and Vietnam. Our findings reveal a trend acc...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.09.06
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to investigate whether insight and mentalizing abilities are related to the severity of Obsessive Compulsive Disorder (OCD) in treatment resistant OCD. We look at the association between treatment resistance, insight, and mentalizing ability. METHODS:The study was conducted with 71 O...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.05.02.2
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:A defense mechanism is an automatic psychological process necessary for successful adaptation. It reflects adaptive capacity. The purpose of this study is to explore the relationship between the adaptation ability of individuals who face mandatory military service and the pattern of defense mechanisms. METHO...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.11.07
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:Coping can be defined as the reactions to harm or distress individuals take to reduce stress. This study aimed to determine how an individual's temperament and character is correlated with the person's main coping method. METHODS:The Korean version of the Ways of Coping Questionnaire and Temperament and Char...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.0084
更新日期:2020-01-01 00:00:00
abstract::Hallervorden-Spatz disease (HSD) is a rare autosomal-recessive hereditary disorder characterized by the early onset of progressive movement alterations, including dystonia, rigidity, choreoathetosis, and mental deterioration. HSD is also associated with a variety of psychiatric symptoms, primarily depression and menta...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2009.6.3.226
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:This study assessed the associations of the abnormal brain activation and functional connectivity (FC) during memory processing and brain volume alteration in conjunction with psychiatric symptom severity in patients with obsessive-compulsive disorder (OCD). METHODS:Twenty-OCD patients and 20-healthy control...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2020.0124
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:Seasonal affective disorder and seasonal changes in mood and behavior are associated with several genes that regulate circadian rhythms. In this study, we investigated the relationship between the C825T polymorphism of the G-protein β3 subunit and seasonal variations in mood and behavior in a young healthy Ko...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2017.09.21
更新日期:2018-02-01 00:00:00