Hematopoietic Stem and Immune Cells in Chronic HIV Infection.

abstract：:Stem cells are a promising cell source for regenerative medicine. Stem cell differentiation must be regulated for applications in regenerative medicine. Stem cells are surrounded by extracellular matrix (ECM) in vivo. The ECM is composed of many types of proteins and glycosaminoglycans that assemble into a complex str...

journal_title：Stem cells international

authors： Hoshiba T,Chen G,Endo C,Maruyama H,Wakui M,Nemoto E,Kawazoe N,Tanaka M

更新日期：2016-01-01 00:00:00

abstract：:This study evaluated the efficacy of mesenchymal stem cells (MSCs) from bone marrow of a third-party donor for refractory aGVHD. We report the first experience using MSCs to treat refractory aGVHD in 33 pediatric patients undergoing allogeneic HSCT from Turkey. Totally, 68 doses of bone marrow derived MSCs were infuse...

journal_title：Stem cells international

authors： Erbey F,Atay D,Akcay A,Ovali E,Ozturk G

更新日期：2016-01-01 00:00:00

abstract：:The aryl hydrocarbon receptor (AhR) is a transcription factor belonging to the basic helix-loop-helix/PER-ARNT-SIM family. It is activated by a variety of ligands, such as environmental contaminants like polycyclic aromatic hydrocarbons or dioxins, but also by naturally occurring compounds and endogenous ligands. Bind...

journal_title：Stem cells international

authors： Dietrich C

更新日期：2016-01-01 00:00:00

abstract：:Beer is one of the most consumed alcoholic beverages in the world, rich in chemical compounds of natural origin with high nutritional and biological value. It is made up of water, barley malt, hops, and yeast. The main nutrients are carbohydrates, amino acids, minerals, vitamins, and other compounds such as polyphenol...

journal_title：Stem cells international

authors： Di Domenico M,Feola A,Ambrosio P,Pinto F,Galasso G,Zarrelli A,Di Fabio G,Porcelli M,Scacco S,Inchingolo F,Quagliuolo L,Ballini A,Boccellino M

更新日期：2020-10-10 00:00:00

abstract：:Background and Objectives. Culture expanded multipotential stromal cells (MSCs) have considerable potential for bone regeneration therapy but their wider use is constrained by the lack of simple and predictive assays of functional potency. Extended passaging leads to loss of multipotency but speed of decline depends o...

journal_title：Stem cells international

authors： Churchman SM,Boxall SA,McGonagle D,Jones EA

更新日期：2017-01-01 00:00:00

abstract：:Myocardial infarction is a leading cause of death among all cardiovascular diseases. Cell therapies using a cell population enriched with endothelial progenitor cells (EPCs), expanded CD133+ cells, have promise as a therapeutic option for the treatment of ischemic areas after infarction. Recently, secreted membrane ve...

journal_title：Stem cells international

authors： Angulski ABB,Capriglione LGA,Barchiki F,Brofman P,Stimamiglio MA,Senegaglia AC,Correa A

更新日期：2019-12-01 00:00:00

abstract：:Ion channels orchestrate directed flux of ions through membranes and are essential for a wide range of physiological processes including depolarization and repolarization of biomechanical activity of cells. Besides their electrophysiological functions in the heart, recent findings have demonstrated that ion channels a...

journal_title：Stem cells international

authors： Keßler M,Just S,Rottbauer W

更新日期：2012-01-01 00:00:00

abstract：:Tumor microenvironment has been implicated in tumor development and progression. As a three-dimensional tumor microenvironment model, air liquid interface (ALI) organoid culture from oncogene transgenic mouse gastrointestinal tissues was recently produced. However, ALI organoid culture system from tissues of colorecta...

journal_title：Stem cells international

authors： Usui T,Sakurai M,Enjoji S,Kawasaki H,Umata K,Ohama T,Fujiwara N,Yabe R,Tsuji S,Yamawaki H,Hazama S,Takenouchi H,Nakajima M,Tsunedomi R,Suzuki N,Nagano H,Sato K

更新日期：2016-01-01 00:00:00

abstract：:There are remarkable similarities in the description of cancer stem cells (CSCs) and cancer cells with mesenchymal phenotype. Both cell types are highly tumorigenic, resistant against common anticancer treatment, and thought to cause metastatic growth. Moreover, cancer cells are able to switch between CSC and non-CSC ...

journal_title：Stem cells international

authors： Gener P,Seras-Franzoso J,Callejo PG,Andrade F,Rafael D,Martínez F,Montero S,Arango D,Sayós J,Abasolo I,Schwartz S Jr

更新日期：2018-10-10 00:00:00

abstract：:Myocarditis is a common inflammatory cardiomyopathy, associated with cardiomyocyte apoptosis, which can lead to chronic left ventricular dysfunction. Under conventional heart failure therapy, inflammatory cardiomyopathy typically has a progressive course, indicating a need for alternative therapeutic strategies to imp...

journal_title：Stem cells international

authors： Miteva K,Van Linthout S,Volk HD,Tschöpe C

更新日期：2013-01-01 00:00:00

abstract：:Intestinal stem cells are located at the base of the crypts and are surrounded by a complex structure called niche. This environment is composed mainly of epithelial cells and stroma which provides signals that govern cell maintenance, proliferation, and differentiation. Understanding how the niche regulates stem cell...

journal_title：Stem cells international

authors： Gjorevski N,Ordóñez-Morán P

更新日期：2017-01-01 00:00:00

abstract：:Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are characterized by their unique capacity to stepwise differentiate towards any particular cell type in an adult organism. Pluripotent stem cells provide a beneficial platform to model hereditary diseases and even cancer development. While the inc...

journal_title：Stem cells international

authors： Hohwieler M,Müller M,Frappart PO,Heller S

更新日期：2019-02-25 00:00:00

abstract：:Stem cell therapy with neural precursor cells (NPCs) has the potential to improve neuroregeneration after spinal cord injury (SCI). Unfortunately, survival and differentiation of transplanted NPCs in the injured spinal cord remains low. Growth factors have been successfully used to improve NPC transplantation in anima...

journal_title：Stem cells international

authors： Younsi A,Zheng G,Scherer M,Riemann L,Zhang H,Tail M,Hatami M,Skutella T,Unterberg A,Zweckberger K

更新日期：2020-06-17 00:00:00

abstract：:The development of chemoresistance to cisplatin regimens causes a poor prognosis in patients with advanced NSCLC. The role of noncanonical Wnt signaling in the regulation of properties of lung cancer stem cells and chemoresistance was interrogated, by accessing capacities of cell proliferation, migration, invasion, an...

journal_title：Stem cells international

authors： Yang J,Zhang K,Wu J,Shi J,Xue J,Li J,Chen J,Zhu Y,Wei J,He J,Liu X

更新日期：2016-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are a reliable source for cell-based regenerative medicine owing to their multipotency and biological functions. However, aging-induced systemic homeostasis disorders in vivo and cell culture passaging in vitro induce a functional decline of MSCs, switching MSCs to a senescent status with...

journal_title：Stem cells international

authors： Wang R,Wang Y,Zhu L,Liu Y,Li W

更新日期：2020-09-10 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/3978595.]. ...

journal_title：Stem cells international

authors： Zadroga A,Jezierska-Woźniak K,Czarzasta J,Barczewska M,Wojtkiewicz J,Maksymowicz W

更新日期：2017-01-01 00:00:00

abstract：:Ischemic heart disease affects a majority of people, especially elderly patients. Recent studies have utilized autologous adult stem/progenitor cells as a treatment option to heal cardiac tissue after myocardial infarction. However, donor cells from aging patients are more likely to be in a senescent stage. Rejuvenati...

journal_title：Stem cells international

authors： Kaur G,Cai C

更新日期：2018-03-29 00:00:00

abstract：Background:Cancer stem cell (CSC) promotes angiogenesis which plays an important role in tumor occurrence, growth, and metastasis. Accurately, quantifying the tumor vasculature can help understanding CSC characteristics and improve cancer diagnosis, therapy planning, and evaluation. The objective of this study is to pr...

journal_title：Stem cells international

authors： Zhang L,Zheng F,Peng Z,Hu Z,Yang Z

更新日期：2018-04-03 00:00:00

abstract：:The maternal part of the placenta, the decidua, consists of maternal immune cells, decidual stromal cells, and extravillous fetal trophoblasts. In a successful pregnancy, these cell compartments interact to provide an intricate balance between fetal tolerance and antimicrobial defense. These processes are still poorly...

journal_title：Stem cells international

authors： Solders M,Gorchs L,Gidlöf S,Tiblad E,Lundell AC,Kaipe H

更新日期：2017-01-01 00:00:00

abstract：:A major challenge in cartilage repair is the lack of chondrogenic cells migrating from healthy tissue into damaged areas and strategies to promote this should be developed. The aim of this study was to evaluate the effect of peripheral blood derived mononuclear cell (PBMC) stimulation on mesenchymal stromal cells (MSC...

journal_title：Stem cells international

authors： Hopper N,Wardale J,Howard D,Brooks R,Rushton N,Henson F

更新日期：2015-01-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility in women of reproductive age. Chronic inflammation is considered to be the cause of ovarian dysfunction. Increasing evidence in animal studies and in preliminary clinical trials has demonstrated that MSCs possess immunomodulatory effe...

journal_title：Stem cells international

authors： Xie Q,Xiong X,Xiao N,He K,Chen M,Peng J,Su X,Mei H,Dai Y,Wei D,Lin G,Cheng L

更新日期：2019-09-12 00:00:00

abstract：:Previously, we demonstrated a high quality of minerals formed by serum-free cultured jaw periosteal cells (JPCs) by Raman spectroscopy but the mineralization extent was not satisfactory. In the present study, we analyzed the proliferation and mineralization potential of human platelet lysate- (hPL-) cultured JPCs in c...

journal_title：Stem cells international

authors： Wanner Y,Umrath F,Waidmann M,Reinert S,Alexander D

更新日期：2017-01-01 00:00:00

abstract：:Mandibular bone defect reconstruction is an urgent challenge due to the requirements for daily eating and facial aesthetics. Three-dimensional- (3D-) printed titanium (Ti) scaffolds could provide patient-specific implants for bone defects. Appropriate load-bearing properties are also required during bone reconstructio...

journal_title：Stem cells international

authors： Yu L,Wu Y,Liu J,Li B,Ma B,Li Y,Huang Z,He Y,Wang H,Wu Z,Qiu G

更新日期：2018-09-05 00:00:00

abstract：:The application of human bone marrow mesenchymal stem cells (hBM-MSCs) in cell-based clinical therapies is hindered by the limited number of cells remaining after the initial isolation process and by cellular senescence following in vitro expansion. Understanding the process of in vitro senescence in hBM-MSCs would en...

journal_title：Stem cells international

authors： Xu Z,Wu W,Shen F,Yu Y,Wang Y,Xiang C

更新日期：2019-07-11 00:00:00

abstract：:In cholestatic liver diseases, impaired bile excretion disrupts lipid homeostasis. We investigated changes of lipid metabolism, including mitochondrial β-oxidation, in a rat model of bile duct ligation (BDL) in which chorionic plate-derived mesenchymal stem cells (CP-MSCs) were transplanted. Serum cholesterol level, w...

journal_title：Stem cells international

authors： Lee YB,Choi JH,Kim EN,Seok J,Lee HJ,Yoon JH,Kim GJ

更新日期：2017-01-01 00:00:00

abstract：:Tendinopathy is a tendon disorder characterized by activity-related pain, local edema, focal tenderness to palpation, and decreased strength in the affected area. Tendinopathy is prevalent in both athletes and the general population, highlighting the need to elucidate the pathogenesis of this disorder. Current treatme...

journal_title：Stem cells international

authors： Zhang X,Lin YC,Rui YF,Xu HL,Chen H,Wang C,Teng GJ

更新日期：2016-01-01 00:00:00

abstract：:Alopecia is caused by a variety of factors which affect the hair cycle and decrease stem cell activity and hair follicle regeneration capability. This process causes lower self-acceptance, which may result in depression and anxiety. However, an early onset of androgenic alopecia is associated with an increased inciden...

journal_title：Stem cells international

authors： Owczarczyk-Saczonek A,Krajewska-Włodarczyk M,Kruszewska A,Banasiak Ł,Placek W,Maksymowicz W,Wojtkiewicz J

更新日期：2018-08-05 00:00:00

abstract：:Blastocyst injection and morula aggregation are commonly used to evaluate stem cell pluripotency based on chimeric contribution of the stem cells. To assess the protocols for generating chimeras from stem cells, 8-cell mouse embryos were either injected or cocultured with mouse embryonic stem cells and induced pluripo...

journal_title：Stem cells international

authors： Guo J,Wu B,Li S,Bao S,Zhao L,Hu S,Sun W,Su J,Dai Y,Li X

更新日期：2014-01-01 00:00:00

abstract：:The latest research achievements in the field of stem cells led in 2016 to the publication of "Guidelines for Stem Cell Research and Clinical Translation" by the International Society for Stem Cell Research (ISSCR). Updating the topics covered in previous publications, the new recommendations offer interesting ethical...

journal_title：Stem cells international

authors： Frati P,Scopetti M,Santurro A,Gatto V,Fineschi V

更新日期：2017-01-01 00:00:00

abstract：:Aging of population brings related social problems, such as muscle attenuation and regeneration barriers with increased aging. Muscle repair and regeneration depend on muscle stem cells (MuSCs). Obstructive sleep apnea (OSA) rises in the aging population. OSA leads to hypoxia and upper airway muscle injury. However, l...

journal_title：Stem cells international

authors： Zhu LY,Yu LM,Zhang WH,Deng JJ,Liu SF,Huang W,Zhang MH,Lu YQ,Han XX,Liu YH

更新日期：2020-03-04 00:00:00