[The effect of levobunolol eyedrops on trabecular outflow of aqueous humor in chronic simple glaucoma].

Abstract:

:The present paper reports a double-blind, cross-over, randomized study in which 31 patients (62 eyes) suffering from open-angle glaucoma were included. These patients were treated for one year with 0.5% levobunolol and 0.5% timolol ophthalmic solutions and followed up. Tonographic examinations of outflow facility showed a statistically significant increase following topical applications of 0.5% levobunolol, while there was little change with 0.5% timolol. The difference in the effect of outflow facility due to instillations of 0.5% levobunolol and 0.5% timolol can be explained by the different pharmacokinetic profiles of the two beta-blocker solutions in topical ocular application.

journal_name

Klin Monbl Augenheilkd

authors

Călugăru M

subject

Has Abstract

pub_date

1989-03-01 00:00:00

pages

164-9

issue

3

eissn

0023-2165

issn

1439-3999

journal_volume

194

pub_type

临床试验,杂志文章,随机对照试验
  • [Factors influencing applanation tonometry - a practical approach].

    abstract::Applanation tonometry has been the gold standard in clinical ophthalmology for more than fifty years. The most popular factor is central corneal thickness that is now routinely considered in glaucoma management. However, other individual features of the cornea can also play a key role for the interpretation of the app...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0029-1246037

    authors: Rosentreter A,Neuburger M,Jordan JF,Schild AM,Dietlein TS

    更新日期:2011-02-01 00:00:00

  • [Fluorescein fundus angiography of the iris (author's transl)].

    abstract::A special method of examining hemodynamic and hydrodynamic conditions of the iris and the ciliary body is described. The process is based on the injection of fluorescein solution into the vortex vein of a rabbit. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057677

    authors: Bisantis C,Romeo G

    更新日期:1980-10-01 00:00:00

  • [Congenital fibrosis syndrome. Considerations on etiology, genetics and surgical therapy].

    abstract::Fibrosis syndrome has been a well-known clinical entity for more than a century. Nevertheless, there are still some unresolved questions concerning its etiology, chronological course, and optimal timing of surgery. On the basis of their experience in 12 cases (2 unilateral, 10 bilateral, 7 with eye muscles and/or lid ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046253

    authors: Boergen KP,Lorenz B,Müller-Höcker J

    更新日期:1990-08-01 00:00:00

  • [Optimised frontal suspension for correction of complicated ptosis].

    abstract::Complicated ptosis can be corrected by frontal suspension with autologous fascia lata. Via an open approach, the fascia is implanted between the brow and the tarsal plate behind the septum. The oblique implantation between the tarsus and the brow preserves the flexibility of elevation, closure and blinking of the uppe...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1281848

    authors: Pfeiffer MJ

    更新日期:2012-01-01 00:00:00

  • [Familial cataract in plasma galactitol increase without known enzyme defect].

    abstract:BACKGROUND:Several enzyme defects of the galactose pathway may lead to cataract formation. We report on a family with familiar cataract. PATIENTS:A 2-year-old Turkish girl (daughter of first cousins) presented with dense cortical and subcapsular opacifications and mature cataract respectively. Bilateral phacectomy, pl...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034710

    authors: Budde M,Gusek-Schneider GC,Jünemann A,Jansen F,Shin YS

    更新日期:1999-10-01 00:00:00

  • [Auto-allo-keratoplasty (with special reference to chondrokeratoprosthesis procedure) (author's transl)].

    abstract::Biological, rather then purely technical approach seems to be very essential to ensure better results in alloplasty of the cornea. The diseased corneal tissue (especially, after corneal burns) usually fails to accept a keratoprosthesis permanently. The cornea must, therefore, be biologically reconstructed by transplan...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Krasnov MM

    更新日期:1976-05-01 00:00:00

  • [An in-vivo evaluation of Brilliant Blue G in macular surgery].

    abstract:OBJECTIVE:The aim of this study was to evaluate the functional outcome of Brilliant Blue G (BBG) and the staining properties in macular surgery. METHODS:BBG was applied during vitrectomy for macular holes (n = 21) or epiretinal membranes (n = 18) in a prospective, non-comparative consecutive series of patients (Brilli...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0031-1273351

    authors: Höing A,Remy M,Dirisamer M,Priglinger S,Schönfeld CL,Kampik A,Haritoglou C

    更新日期:2011-08-01 00:00:00

  • [Botulinum Toxin - New Developments in Ophthalmology].

    abstract::Botulinum toxin is recognised as the gold standard for the treatment of essential blepharospasm and hemifacial spasm, which is similar in effect in synkinesis after facial nerve palsy. The injection intervals can be adjusted according to the patients' needs and be shortened for up to six weeks in cases of eyelid cramp...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0042-122339

    authors: Wabbels B

    更新日期:2018-06-01 00:00:00

  • [The effect of natural and artificial light via the eye on the hormonal and metabolic balance of man (author's transl)].

    abstract::Examinations of hormone levels in blind persons compared with almost blind and people with normal vision and hormone evaluation with increased artificial light exposure show a definite stimulating effect of light on the human hormonal balance. The effect of light is mediated by an intact perception of light by the eye...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Hollwich F,Dieckhues B,Schrameyer B

    更新日期:1977-07-01 00:00:00

  • [Is timolol effective in neovascular glaucoma? (author's transl)].

    abstract::Timolol lowered intraocular pressure in six patients with severe neovascular glaucoma only from about 45 mmHg to about 38 mmHg. The intense pain suffered by five patients was not alleviated. Hence, Timolol treatment does not seem very effective in neovascular glaucoma, although it may be of some value as a supplement ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057639

    authors: Bischoff P,Speiser P

    更新日期:1980-01-01 00:00:00

  • [Closure of the central artery of the retina in progressive scleroderma (author's transl)].

    abstract::In the present paper a case of generalized scleroderma with concomitant central arterial occlusion is reported. To our knowledge this coincidence of generalized scleroderma and central arterial occlusion has not been described so far. As fibrinoid necrosis and proliferative changes of the choroidal vessels occur with ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Berndt K,Hoffmann A

    更新日期:1977-10-01 00:00:00

  • [Experimental studies of the significance of the renin-angiotensin system in the retina. A review].

    abstract::BACKGROUND Many peptides now identified in the brain were previously thought of as exclusively peripheral hormones. Among those, the renin-angiotensin system (RAS) is not only found to be of great importance in peripheral vasomotor and electrolyte homeostasis but also acts as neurotransmitter or modulator in the centr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1045478

    authors: Jacobi PC,Jurklies B,Kohler K,Zrenner E

    更新日期:1994-06-01 00:00:00

  • [Optic Disk Drusen: Historical and Up-To-Date Aspects].

    abstract::Optic disc drusen are an important differential diagnosis in the diagnostic evaluation of a prominent optic nerve head. Drusen of the optic disc occur in 0.34 to 2.4 % of human individuals and manifest themselves bilaterally in three of four cases. Drusen are found six times more often within histological sections tha...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0042-101554

    authors: Nentwich MM,Maertz J,Rudolph G

    更新日期:2016-03-01 00:00:00

  • [Investigations into mucous membrane compatibility using the Endorfer Jod-Thermalsole treatment of the conjunctivae of rabbits (author's transl)].

    abstract::The conjunctivae of nine rabbits of the same breed were used to compare the local compatibility of the Endorfer Jod-Thermalsole with that of a physiological NaCl solution. The neuroleptanalgesics were administered using perfusion techniques. The reddening thus caused was used to measure the degree of inflammation. The...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1055295

    authors: Hirsch E

    更新日期:1981-01-01 00:00:00

  • ["White dot syndromes" in childhood].

    abstract:BACKGROUND:The term "white dot syndromes" describes a group of heterogeneous inflammatory disorders of the choriocapillaris. They were first described a few decades ago and our knowledge about these variable diseases is very limited, especially in regard to their overall incidence and their differential diagnostic rele...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2007-963179

    authors: Spital G,Heiligenhaus A,Scheider A,Pauleikhoff D,Herbort CP

    更新日期:2007-06-01 00:00:00

  • [O'Connor's surgical method in abducens nerve paralysis].

    abstract::Eighteen patients who underwent surgery for nervus abducens paresis (NAP), were kept under observation for up to 23 years after the operation. Three patients had paresis of both nerves. The operation, employing O'Connor's method (11 patients) included the grafting of split inferior and superior rectus muscles on to th...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054369

    authors: Miettinen P,Aine E,Partanen M

    更新日期:1985-11-01 00:00:00

  • [Optimization of irradiation time in the treatment of malignant melanoma of the choroid with beta applicators (106Ru/106Rh)].

    abstract::Brachytherapy with 106Ru/106Rh necessitates protracted irradiation because the applicators have to be sutured to the sclera. Protracted radiotherapy causes more intensive damage in tumor cells with increased metabolism and a higher mitosis rate than in normal tissue. Beta irradiation of rabbit eyes with 0.258-0.231 Gy...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050770

    authors: Lommatzsch PK,Weise B,Ballin R

    更新日期:1986-08-01 00:00:00

  • [Inferior nasal transposition of the lateral rectus muscle for third nerve palsy].

    abstract:OBJECTIVE:The choice and extent of extraocular muscle surgery in N.III palsy are based on the specific pattern and degree of the palsy. In severe paralysis the eye has to be shifted from an exotropic to a straight ahead position. Additionally, a change in vertical position may be desirable. To reach this aim, transposi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0029-1245737

    authors: Gräf M,Lorenz B

    更新日期:2010-10-01 00:00:00

  • [Experiences with the implantation of anterior chamber lenses (author's transl)].

    abstract::On account of the good results with the new generation of anterior chamber lenses reported by C.D. Binkhorst, the implantation of lenses was begun in 1969 at the Department of Ophthalmology in Bremen and 350 anterior chamber lenses were implanted till 1st Febr. 1977. After the presentation of indications and the opera...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:

    authors: Draeger J,Koudelka A,Modzanowski P

    更新日期:1978-03-01 00:00:00

  • [Real-time monitoring of a femtosecond laser in Sub-Bowman Keratomileusis on human donor eyes using OCT].

    abstract:PURPOSE:In LASIK (laser in situ keratomileusis) the thickness of the corneal flap is important since it is the residual corneal bed that determines corneal stability. The introduction of real-time OCT visualisation of the corneal layers during the fs-laser cut should enable the surgeon to control and monitor the positi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0028-1109682

    authors: Kermani O,Oberheide U,Will GF,Massow O,Lubatschowski H

    更新日期:2009-12-01 00:00:00

  • [Keratoplasty -- a simple classification/terminology of current treatment options].

    abstract::Thanks to technical advances the surgical options for corneal grafting have been widely expanded in recent years. Promoted by new instruments and techniques for intrastromal dissection a number of variations of lamellar keratoplasty, including descriptive terms and abbreviations have been suggested. This creative chao...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-858461

    authors: Geerling G,Seitz B

    更新日期:2005-08-01 00:00:00

  • [Ultrastructural changes in keratoconus].

    abstract::In case of keratoconus the epithelial cells are also participating in the pathological processes. Their activity of producing basal membrane is increased. In the stroma four cell types are found; two of them are normal elements. The origin of the two pathological forms is unknown. They may represent as well vagrant ce...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Süveges I

    更新日期:1979-03-01 00:00:00

  • [Genodermatosis with changes in eyes not previously described (author's transl)].

    abstract::Report on a patient with several symptoms which had not previously occurred together. The main symptom is palmoplantar keratosis; further alterations were kypho-skoliosis, brachytelephalangia of the thumbs, and in the eyes, keratoconus, a cataract and electroretinographic alterations. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057732

    authors: Richard G,Wreesmann P

    更新日期:1980-12-01 00:00:00

  • [Evaluation of glaucomas. Frequently misdiagnosed glaucoma conditions].

    abstract::On the basis of a number of examples the authors describe specific glaucomas which have often reached their final stages by the time the patients are referred to the clinic. They include sub-acute and chronic angle-closure glaucoma, pseudoexfoliation syndrome, and pigmentary glaucoma. An unpleasant feature of these gl...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046389

    authors: Gloor BP,Robert Y

    更新日期:1989-05-01 00:00:00

  • [Iritis and optic nerve meningitis--initial symptoms of latent syphilis].

    abstract::A 19-year-old woman presented in the latent phase of secondary syphilis with chronic bilateral anterior uveitis and a slightly elevated optic disk with indistinct margins in the left eye; this was interpreted as a meningitis of the optic nerve. Serologic examination revealed the syphilitic infection, which had not pre...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050356

    authors: Barthelmess-Mösler S,Völcker HE

    更新日期:1987-03-01 00:00:00

  • [Pseudoexfoliation syndrome].

    abstract::The Frequency of the Pseudoexfoliation-Syndrom (= PES) was investigated about two months in a prospective study of 1069 patients in the university eye hospital of Zurich. 7.35% of these patients had a PES with or without glaucoma. Among the clinic patients there were 9.9% and among the policlinic patients 6.26%. All o...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045974

    authors: Esmail F

    更新日期:1991-05-01 00:00:00

  • [Comparative studies of the pressure-lowering effect of timolol and phospholine iodide (author's transl)].

    abstract::A comparative study of the intraocular pressure-lowering effects of timolol and phospholine iodide in cases of aphakic glaucoma was carried out. The authors compared the I.O.P.-lowering effect of these two drugs in 30 eyes (30 patients) with aphakic glaucoma over an eight-month observation period. The following was es...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057292

    authors: Christakis C,Mangouritsas N

    更新日期:1981-09-01 00:00:00

  • Vasorelaxing effect of the potassium (K+)-channel opener pinacidil in isolated porcine ciliary arteries.

    abstract:PURPOSE:The aim of this study was to investigate the vasorelaxing properties of pinacidil (a potassium-channel-opener) in isolated porcine ciliary arteries. METHODS:Isometric contractions of isolated porcine ciliary arteries were measured with a myograph system. The vessels were first precontracted with the thromboxan...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2001-15894

    authors: Morf T,Zhu P,Flammer J,Haefliger IO

    更新日期:2001-05-01 00:00:00

  • [High altitude retinal hemorrhages in mountain climbers (author's transl)].

    abstract::A report is given on three patients who noticed an acute deterioration of visual acuity after a sojourn at 5000 altitude caused by retinal hemorrhages. We documented both the ophthalmological examinations such as visual acuity, fundus, perimetry and fluorescence-angiography and the systemic results. During the period ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Vogt C,Greite JH,Hess J

    更新日期:1978-05-01 00:00:00

  • [Exudative reaction after implantation of an artificial lens].

    abstract::Results of clinical observation over post-operative period and degree of exsudative reaction in 240 patients (262 eyes) with implantation of intraocular lenses are analysed. Three types of postoperative course are distinguished: a reactive, postoperative with early exsudative reaction and postoperative with late exsud...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046034

    authors: Georgiew D

    更新日期:1991-06-01 00:00:00