[Periocular sub-tenon triamcinolone acetonide injections for the treatment of retinal angiomatous proliferation (RAP) and occult choroidal neovascularisation].

Abstract:

BACKGROUND:Intravitreal triamcinolone injections are used for the treatment of occult choroidal neovascularisations (CNV) combined with photodynamic therapy (PDT). However, this therapy is not without considerable risks. The periocular mode of application seems to be a logical alternative. PATIENTS AND METHODS:A retrospective case series of 39 eyes with occult CNV either with retinal angiomatous proliferations (RAP) (group A) or with occult choroidal neovascularisation (CNV) (group B), treated with periocular triamcinolone was reviewed. Data regarding efficacy and side effects were extracted. RESULTS:After a mean follow-up of 10 - 11 months 84 % in group A lost < 3 lines of visual acuity (VA). 26 % of them gained > or = 1 line of VA. 16 % lost > or = 3 lines of VA. In group B (19 eyes) VA was stable in 100 %, whereas 20 % gained > or = 1 line. Both groups showed similar results for magnification requirement (MR). A rise in intraocular pressure was found in 15 %. CONCLUSION:In patients with RAP or occult CNV sub-tenon injections seem to delay moderate to severe visual loss. Whether larger randomised controlled studies regarding this treatment are still relevant in the era of anti-VEGF treatments remains to be seen.

journal_name

Klin Monbl Augenheilkd

authors

Rutishauser-Arnold Y,Thölen AM

doi

10.1055/s-2006-927396

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

269-73

issue

4

eissn

0023-2165

issn

1439-3999

journal_volume

224

pub_type

杂志文章
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    pub_type: 杂志文章

    doi:

    authors: Naumann GO,Eisert S,Gieler J,Baur KF

    更新日期:1977-06-01 00:00:00

  • [Hereditary Optic Neuropathies].

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    doi:10.1055/a-0583-6290

    authors: Rüther K

    更新日期:2018-06-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Pfannkuch F

    更新日期:1978-09-01 00:00:00

  • [Retinal dysplasia with hydrocephalus (author's transl)].

    abstract::A Study is described of a family in which four children of the same generation died during early childhood; three of them had an obvious hydrocephalus. Two of the latter could be examined clinically, and their eyes removed for pathology. One of them presented clinically bilateral leucocoria; histology showed a total d...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Gerhard JP,Brini A,Willard D,Rohmer A,Messer J

    更新日期:1978-04-01 00:00:00

  • [Laser treatment of diabetic maculopathy].

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1050820

    authors: Giovannini A,Costantini G,Amato GP,Bottazzi M

    更新日期:1986-11-01 00:00:00

  • [Enzymatically induced posterior vitreous detachment in proliferative diabetic vitreoretinopathy].

    abstract:BACKGROUND:Complete detachment of the posterior vitreous cortex is an important aim in the treatment of proliferative diabetic vitreoretinopathy (PDVR). Today a posterior vitreous detachment (PVD) can only be achieved during vitrectomy. A randomized pilot study was started to evaluate wether intravitreally injected TPA...

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    doi:10.1055/s-2008-1034754

    authors: Hesse L,Kroll P

    更新日期:1999-02-01 00:00:00

  • [Intrastromal keratorhexis with the Nd:YAG laser--a possible method of refractive surgery?].

    abstract::A new method of refractive corneal surgery is presented. With the q-switched Nd:YAG-laser Visulas (Zeiss-Oberkochen) we succeed in altering the optical power of the cornea of rabbits, pigs and humans. The number of applied laser spots and the distribution pattern influence the way and the amount of change of refractio...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046315

    authors: Höh H,Becker KW

    更新日期:1990-12-01 00:00:00

  • [The best spectacles for vehicle drivers (author's transl)].

    abstract::Spectacles worn by vehicle drivers should fulfil the demands set down by DIN 58 216 standards and should furthermore be constructed in such a manner that the binocular field of vision is impaired as little as possible. In this connection, the nasal parts of the frame are particularly important. The external and intern...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Reiner J,Grewe R

    更新日期:1978-07-01 00:00:00

  • [Secondary ocular syphilis with chorioretinitis of the posterior pole - a case report].

    abstract:BACKGROUND:Diagnosis of syphilis is often very difficult due to the absence of typical organ manifestation. In addition syphilis has the ability to imitate any ocular inflammation. This may result in misdiagnosis and delay of appropriate antimicrobial therapy. Up to now the first choice therapy is penicillin. CASE REP...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2001-17141

    authors: Stübiger N,Denk PO,Kötter I,Zierhut M

    更新日期:2001-08-01 00:00:00

  • [Effect of a single oral dose of propranolol or metoprolol on the intraocular pressure of persons without glaucoma (author's transl)].

    abstract::Oral doses of propranolol and metoprolol were tested on 24 patients without glaucoma. The aim of this study was to compare the decrease in intraocular pressure in normal eyes following a single oral dose of propranolol or metoprolol. A statistically significant decrease in IOP was noticed, but no difference was seen b...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Merté HJ,Merkle W

    更新日期:1980-01-01 00:00:00

  • [A new apparatus for testing binocular vision (author's transl)].

    abstract::The Optometer can be used in a binocular manner if the loupe-lens is replaced by a concave mirror of appropriate size and form. The concave mirror or the plane mirror connected to it can be partially transparent. With an appropriate arrangement of these elements the test field can be seen in free space. The image can ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Reiner J

    更新日期:1977-01-01 00:00:00

  • [Posterior vitreous detachment with collapse, and peripheral retinal degeneration in the aetiology of idiopathic retinal detachment. A synapsis of clinical observations and anatomical studies (author's transl)].

    abstract::The crucial aetiological factors of idiopathic retinal detachment are posterior vitreous detachment with collapse, and degenerative lesions in the fundus periphery. Posterior vitreous detachment does not imply diagnostic problems to the expert in this field. On the other hand, the peripheral retinal degenerations incl...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057296

    authors: Hruby K

    更新日期:1981-10-01 00:00:00

  • [Retinal angiomatoses].

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    doi:10.1055/s-2008-1050609

    authors: Witmer R

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  • [Glaucoma without ocular hypertension. A clinical study].

    abstract::One hundred eighty-four glaucomatous eyes (125 patients) with visual field defects of Stage I and II in the central visual field were examined with the Octopus perimeter 201, Program 31 or 33, and were divided into 3 groups according to maximum intraocular pressures: (1) low-tension glaucoma (21 mm Hg), (2) glaucoma s...

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    doi:10.1055/s-2008-1050918

    authors: Gramer E,Leydhecker W

    更新日期:1985-04-01 00:00:00

  • [Acute corneal endothelial cell loss].

    abstract::Corneal endothelial cell loss may result from endogenic causes, such as acute angle-closure glaucoma, or exogenic causes, such as corneal contusion, corneal perforation or surgery involving the anterior chamber. The extent of endothelial cell loss varies with the severity of trauma. Despite the different causes the re...

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    doi:10.1055/s-2008-1054698

    authors: Mellin KB,Waubke TN

    更新日期:1983-01-01 00:00:00

  • [Strategies of visual acuity assessment].

    abstract::Visual acuity can be assessed by different strategies. The constant-stimulus-, the stair-case-, the Best-PEST-strategies, and the EN ISO 8596 are discussed. In cases of presumed psychogenic visual impairment and malingering it can be useful to modify these strategies striving for a determination of the (minimum) visua...

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    doi:10.1055/s-2004-812893

    authors: Gräf M

    更新日期:2004-07-01 00:00:00

  • [Type I lattice corneal dystrophy. Clinical and molecular genetic study of a large family].

    abstract:BACKGROUND:Lattice corneal dystrophy type I is one of the frequent forms of stromal dystrophies following autosomal dominant inheritance. The beta-IG-h3 gene encoding keratoepithelin on the long arm of chromosome 5 has recently been described as disease gene for lattice corneal dystrophy type I as well as for three oth...

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    doi:10.1055/s-2008-1034852

    authors: Meins M,Kohlhaas M,Richard G,Gal A

    更新日期:1998-03-01 00:00:00

  • [Genodermatosis with changes in eyes not previously described (author's transl)].

    abstract::Report on a patient with several symptoms which had not previously occurred together. The main symptom is palmoplantar keratosis; further alterations were kypho-skoliosis, brachytelephalangia of the thumbs, and in the eyes, keratoconus, a cataract and electroretinographic alterations. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057732

    authors: Richard G,Wreesmann P

    更新日期:1980-12-01 00:00:00

  • [Arteriovenous malformation of the orbit].

    abstract::Arteriovenous malformation is a rare vascular disease of the orbit that has to be differentiated from arteriovenous fistulas (e.g., of the carotid sinus), arterial aneurysms, the varices and the angiomas. It develops in the presence of an underlying constitutional maldifferentiation of the vascular bed but usually onl...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1046343

    authors: Witschel H,Grannemann D

    更新日期:1989-02-01 00:00:00

  • [Parapapillary autofluorescence as indicator for glaucoma].

    abstract:BACKGROUND:A pronounced fundus autofluorescence (lipofuscin) occurs in eyes with AMD. Parapapillary lipofuscin accumulation in the retinal pigment epithelial cells was observed in eyes with advanced glaucoma histologically. The aim of this study was to evaluate the parapapillary autofluorescence (PAF) in vivo in health...

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    authors: Viestenz A,Langenbucher A,Mardin CY

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  • [Treatment with azathioprine of peripheral chronic cyclitis with cystoid edema of the macula (author's transl)].

    abstract::Nine patients with peripheral chronic cyclitis and cystic edema of the macula were treated with azathioprine and small doses of corticosteroids. The results were quite good. In fact the inflammatory signs subsided nearly completely, while the cystic edema was still present in 2 cases. Besides excellent compatibility, ...

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    pub_type: 临床试验,杂志文章

    doi:

    authors: Charamis I,Skouras I

    更新日期:1977-03-01 00:00:00

  • [Initial results in percutaneous radiotherapy of malignant melanomas of the choroid with the linear accelerator].

    abstract::Twenty-seven eyes harboring a choroidal melanoma which could not be treated by other methods were treated with external beam radiation using a linear accelerator. After a mean follow-up period of 15.6 months 3 eyes had to be enucleated. In two eyes fresh tumors developed, which were successfully treated with local bet...

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    authors: Bornfeld N,Alberti W,Foerster MH,Gerke E,Wessing A,Meyer-Schwickerath G

    更新日期:1984-09-01 00:00:00

  • [Evaluation of the image quality of bi- and multifocal intraocular lenses with a new optical system].

    abstract::By means of a new optical device developed by Reiner, an "optical implantation" of 6 different bi- and multifocal intraocular lenses (MIOLs) was performed in 20 young healthy subjects, and results were compared with those of a monofocal reference IOL. The following parameters were investigated: distance and near visua...

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    doi:10.1055/s-2008-1045916

    authors: Eisenmann D,Jacobi KW,Reiner J

    更新日期:1992-12-01 00:00:00

  • [Technical problems in microsurgical processing of preserved donor tissue].

    abstract::The microsurgical processing of longterm preserved tissue is still a problem for lamellar and perforating keratoplasties. Advantages of donor tissue cut with rotortrephines versus manual trephines are presented. Optimal possibilities of examination and storage of donor tissue are explained. A lamellar microkeratome, a...

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    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1045717

    authors: Draeger J,Kohlhaas M

    更新日期:1992-02-01 00:00:00

  • [Bilateral neuroretinitis with zoster infection].

    abstract:BACKGROUND:Infections with varicella zoster virus may involve the optic nerve and the retina. Different pathomechanisms have been discussed. We present a case with an autoimmune inflammatory reaction according to the clinical course. PATIENT:A 69-year-old female was referred to our clinic because of suspected bilatera...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1034771

    authors: Nicaeus T,Wilhelm H

    更新日期:1999-03-01 00:00:00

  • [Ultrastructure of the hyaloid canal and its retraction during gestation (author's transl)].

    abstract::1. The cells of the hyaloid canal originate from the primitive meningeal cells; 2. The lumen of the hyaloid canal can be observed through the optic nerve up to the subarachnoid space around the optic nerve; 3. Injections of tracer substances into the subarachnoid space of the optic nerve have shown that a communicatio...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1055078

    authors: van der Zypen E,Fankhauser F

    更新日期:1982-05-01 00:00:00

  • [Unusual presentation of retinoblastoma].

    abstract::Among the 185 retinoblastoma patients seen at the Lausanne Retinoblastoma Clinic from 1963-1993, 24 (14%) first presented with another sign than classical leukocoria (60.5%) or strabismus (21.5%). Most of these atypical signs were related to inflammatory complications of unrecognized retinoblastoma; they consisted of ...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1035546

    authors: Balmer A,Gailloud C,Munier F,Lendi B,Uffer S

    更新日期:1994-05-01 00:00:00

  • [Effect of UVA on biosynthesis of melatonin in the retina].

    abstract::No difference in the retinal acetylserotonin-methyltransferase was found in two groups of quail which were exposed to irradiation of 0.1 W/m2 with green and blue light respectively for 1 hour. Decreased retinal enzyme activities (isoelectric point pH 5.0) were observed in response to exposure to green and UVA light co...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1050633

    authors: Cremer-Bartels G,Krause K

    更新日期:1986-04-01 00:00:00

  • [Circumscribed peripheral (equatorial or pre-equatorial) retinoschisis (author's transl)].

    abstract::Circumscribed areas of retinoschisis along or anterior to the Equator occur mainly in elderly subjects. Diagnosis is based on biomicroscopic criteria. ...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1057704

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    更新日期:1980-12-01 00:00:00