[Goals of blood glucose regulation in prevention of diabetic retinopathy].

Abstract:

:In several studies a correlation between blood glucose levels and HbA1 (A1c) and the prevalence of retinopathy was documented. Minimal risk for the onset of retinopathy was observed when HbA1 was below 9% from the beginning of diabetes mellitus. This HbA1 (A1c) value corresponds with values above 7 mmol of blood glucose. In intervention trials with near normal values of blood glucose, initially i.e. during the first months of treatment, an increase of microaneurysm was observed. However, in the next 7 years (as was observed in the Oslo Study) the grade of retinopathy in patients was less severe than in patients with HbA1 > 10%. Only 20% of patients treated conventionally can reach the aim of optimal blood glucose regulation. Obviously, in patients with diabetes beginning before the age of 30, this is the reason why the prevalence for the diabetic retinopathy is 40-98% after 15 years of diabetes. Only the functional insulin therapy allows the achievement of optimal blood glucose control in about 40% of patients without increased risk of hypoglycemia. Therefore, this kind of therapy should be the therapy of choice in a great number of type 1 diabetes patients.

journal_name

Klin Monbl Augenheilkd

authors

Berger W

doi

10.1055/s-2008-1045622

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

437-42

issue

5

eissn

0023-2165

issn

1439-3999

journal_volume

202

pub_type

杂志文章,评审
  • [Results of 1-year use of local pindolol in open-angle glaucoma].

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    authors: Stryz JR,Merté HJ

    更新日期:1985-01-01 00:00:00

  • [Conventional versus digital planimetry of optic disc photograph: a clinical comparative study].

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    更新日期:2001-11-01 00:00:00

  • [Fluorescence angiography in age-related macular degeneration. Study of the incidence of lesions treatable with coagulation].

    abstract:BACKGROUND:The treatment of late age-related Macular Degeneration (AMD) according to the results of prospective clinical studies is indicated in classical choroidal neovascularisations (NV), which can be delineated from the center of the fovea. To evaluate the effectiveness of this therapy, the knowledge of the frequen...

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    更新日期:1996-11-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Wollensak J,Grajewski O

    更新日期:1978-11-01 00:00:00

  • [Polyglycolic acid suture in strabismus surgery (author's transl)].

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1057640

    authors: Demmler N

    更新日期:1980-01-01 00:00:00

  • [Individual postoperative refraction after cataract surgery -- a comparison of optical and acoustical biometry].

    abstract:BACKGROUND:Optical biometry with the IOL-Master is an innovative technique that claims to improve the refractive results of cataract surgery compared to acoustical biometry. METHODS:In 140 consecutive non-selected eyes prior to cataract surgery firstly an optical biometry (IOL-Master, Zeiss, V.2.02) and secondly an ul...

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    doi:10.1055/s-2004-813385

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    更新日期:2004-09-01 00:00:00

  • [The Fieldmaster-200 computer perimeter: a comparative, controlled clinical study of its sensitivity and specificity in glaucomatous field defects (author's transl)].

    abstract::The central visual fields of 119 glaucomatous eyes (78 patients) were evaluated under controlled conditions using the Goldmann kinetic perimeter and the Fieldmaster-200 automatic supra-threshold computer perimeter. Where there were qualitative differences between the two instruments, the high-resolution program 61 of ...

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    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2008-1057325

    authors: Krieglstein GK,Glaab E,Gramer E

    更新日期:1981-11-01 00:00:00

  • [Solitary retinal astrocytoma with "acoustic shadowing"].

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    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035428

    authors: Seitz B,Jonas JB

    更新日期:1995-03-01 00:00:00

  • [Indications, technique and results of anterior vitrectomy (author's transl)].

    abstract::The indications for anterior vitrectomy are presented and the surgical technique is described. An analysis is made of the results of anterior vitrectomy in 93 eyes followed for 4 years and compared with the results of a previous study in which vitreous loss was treated more conservatively. The results of anterior vitr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Luntz MH

    更新日期:1977-06-01 00:00:00

  • [Diagonal incision in capsulotomy for extracapsular cataract extraction].

    abstract::From previous experience with all current surgery methods and kinds of anterior capsulotomy as well as of 6-year follow-up observation we developed our own diagonally-shaped (linear) capsulotomy technique. This technique was used in more than 500 successive extracapsular cataract extractions, followed by implantation ...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1046104

    authors: Mitschischek E

    更新日期:1991-12-01 00:00:00

  • [The value of preoperative calculation of intraocular lenses].

    abstract::In 82 cataract patients the power of the pseudophakos to be implanted was determined. Axial length and anterior chamber depth were measured by ultrasound. The results of keratometry and the echographic data were used for lens power calculation. For the accuracy of prediction the estimated post-operative anterior chamb...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1055264

    authors: Hauff W

    更新日期:1982-11-01 00:00:00

  • [Lowering of intraocular pressure by aqueous solution of bupranolol in chronic uncomplicated glaucoma simplex (author's transl)].

    abstract::In two previous studies the effects of topically applied 1% and 0.2% solutions of bupranolol on intraocular pressure were investigated in 21 and respectively 20 eyes with chronic uncomplicated open-angle glaucoma.--As early as 30 minutes after both solutions a very significant pressure drop, without concomittant pupil...

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    pub_type: 杂志文章

    doi:

    authors: Oancea I,Trif V

    更新日期:1979-05-01 00:00:00

  • [Intraocular pressure values in intubation anesthesia in patients with and without chronic open angle glaucoma].

    abstract:BACKGROUND:A number of clinical studies have investigated the influence of hypnotics and relaxants on intraocular pressure. All of them referred to the normal eye. Our goal was to show if there is a difference in intraocular pressure profile during general anesthesia between eyes with and without primary open angle gla...

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    authors: Hoffmann PC,Köhalmi E,Hütz WW,Eckhardt HB

    更新日期:1998-01-01 00:00:00

  • [Optic neuritis].

    abstract::Optic neuritis is a frequent neuro-ophthalmological disease in which the diagnosis can be based on just a few symptoms and findings. It is not only important to differentiate from other optic nerve disorders but also to recognise special types of optic neuritis, which is mostly only possible during the course of the d...

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  • [Intravitreal Ranibizumab Injection for the Treatment of Occult and Classic CNV in Exsudative AMD].

    abstract:BACKGROUND:Double-blind, randomised, placebo-controlled and multicentre studies have proven an increase in visual acuity in one-third of the patients receiving Ranibizumab (0.5 mg) injections, who suffer from exsudative AMD. The purpose of this study was to evaluate the early effects of intravitreal Ranibizumab therapy...

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    authors: Maier MM,Feucht N,Fegert C,Fiore B,Winkler von Mohrenfels C,Lohmann C

    更新日期:2011-02-01 00:00:00

  • [Inverted In Vitro Confocal Microscopy in Mycotic Keratitis with Corneal Endothelial Epithelial Decompensation].

    abstract::The sensitivity of confocal microscopy ranges between 80 and 90% and thus lies above the sensitivity of pathogen identification by microbiological culture. Typically, in vivo confocal microscopy enables us to diagnose mycotic keratitis non-invasively and atraumatically on the day of admission. Herein we present a pati...

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    doi:10.1055/a-0983-1752

    authors: Daas L,Seitz B,Zimpfer A,Bischoff M,Viestenz A

    更新日期:2019-12-01 00:00:00

  • [Keratitis in measles].

    abstract::We are reporting a case of a 23-year-old patient suffering from measles despite vaccination during childhood. He presented with bilateral punctate keratitis without conjunctival reaction 10 days after the onset of rash. We assume a late immunological reaction, possibly related to earlier vaccination. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2008-1035466

    authors: Trüb PR

    更新日期:1995-05-01 00:00:00

  • [Contribution to the epithelial tumors of the ciliary body (clinical, histopathological and electronmicroscopical observation) (author's transl)].

    abstract::An adenoma of the non pigmented epithelium of the ciliary body was supposed to be an irisciliary body melanoma (32P-test positive) and was treated by irido-cyclectomy. Vision acuity remained 0,4 one year after operation. The tumor formed adenoid tubes lined with a cubical or cylindrical epithelium. The cytoplasm of al...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Lommatzsch P,Vorpahl K,Bauke G,Klug H

    更新日期:1979-01-01 00:00:00

  • [Cyclophotocoagulation with the Nd:YAG-laser].

    abstract::Hopeless glaucoma cases fluctuate between excessive pressures and phthisis. Due to the underlying disease (neovascularization in the chamber angle, chronic inflammation, dysgenesis, aphakia) the customary surgical pressure-lowering operations often fail and medication is also useless. As a "last-ditch" measure, there ...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1046201

    authors: Robert Y,Martenet AC,Milano D

    更新日期:1990-05-01 00:00:00

  • [Intraocular solitary granuloma of toxocara canis (author's transl)].

    abstract::5 cases of intraocular Toxocara canis solitary granuloma are demonstrated. The coincidence of two different aspects of a disease: pseudocoloboma of the macula (toxoplasmosis) in the right and a toxocara solitary granuloma in the left eye of the same patient (case 5) perhaps will furnish proof possibility of foetal inf...

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    pub_type: 杂志文章

    doi:

    authors: Huismans H

    更新日期:1976-08-01 00:00:00

  • [Perimetry in chiasmal syndrome -Liminal and surpraliminal stimuli (author's transl)].

    abstract::The value of static and kinetic perimetry with white and colored stimuli in chiasmal syndrome seems to be equal. The presentation of evenly moving supraliminal targets allows for an evaluation of sensory disturbance. This procedure is even more subjective, variable and difficult to perform accurately. It may reveal, h...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Dannheim F

    更新日期:1977-09-01 00:00:00

  • [Anatomic and subjective success of structured surgical treatment strategy in the management of chronic epiphora - a postoperative analysis of contentment].

    abstract:BACKGROUND:Epiphora is the result of hypersecretion or reduced tear outflow because of relative or absolute obstruction of the lacrimal system. For the treatment a specific surgical procedure is usually required. Herein we present the subjective and objective findings of 243 consecutive patients with non-irritative ind...

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    pub_type: 杂志文章

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    authors: Eisenbeis C,Neppert B,Menke T,Pape S,Schrader S,Geerling G,Müller M

    更新日期:2010-11-01 00:00:00

  • [Cure of scleromalacia perforans manifesting in the course of rheumatoid arthritis with d-penicillamine and fascia lata-autograft (author's transl)].

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    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Balla L,Sziklai P,Oláh M,Kiss G

    更新日期:1975-09-01 00:00:00

  • [Development of retinal vein thrombosis after argon laser photocoagulation (author's transl)].

    abstract::In this paper 21 cases of branch vein thrombosis and 15 cases of central retinal vein thrombosis treated by argon laser photocoagulation are compared with an untreated control group. The visual prognosis after photocoagulation was no better in the treated group than in the control group. After central retinal vein occ...

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    doi:10.1055/s-2008-1057347

    authors: Vidic B,Hiti H,Schuhmann G,Hubel K

    更新日期:1981-12-01 00:00:00

  • [Immunolocalization of fodrin in the retina of vertebrates].

    abstract::Fodrin, a member of the spectrin family, is abundantly found in brain and lens. Based on its often observed peripheral cellular distribution, it is generally believed that fodrin - like other spectrins - participates in the linkage of membrane components to cytoskeletal elements providing their anchorage to distinct, ...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1045994

    authors: Rungger E,Stepanian E,Gilodi N

    更新日期:1991-05-01 00:00:00

  • [Secondary glaucomas caused by intraocular epithelial invasion. A clinico-pathologic study of 30 patients].

    abstract::The clinical data of 30 eyes with intraocular epithelial invasion were correlated to the histopathological findings (15 iridocyclectomies, four diagnostic iridectomies, one corneal button, ten globes). The diffuse (46.7%) and cystic (53.3%) types occurred with equal frequency. The correlation to the clinical data make...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1050215

    authors: Zagorski Z,Shrestha HG,Lang GK,Naumann GO

    更新日期:1988-07-01 00:00:00

  • [Retraction syndrome (author's transl)].

    abstract::A report on 70 cases of retraction syndrome (Stilling-Türk-Duane). The patients presented with typical symptoms: severe limitation of abduction, slight limitation of adduction and convergence, which is always accompanied by retraction of the globe, narrowing of the palpebral fissure, vertical deviation and elevated in...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1055309

    authors: Kaufmann H,Kolling G,Hartwig H

    更新日期:1981-02-01 00:00:00

  • [Calculation of pseudophakic toric intraocular lenses].

    abstract:BACKGROUND:A high corneal astigmatism limits the attainable visual acuity and the ability of correction with spectacles or contact lenses. The astigmatism can also be an impairment for visual rehabilitation, especially after penetrating keratoplasty. A pseudohakic toric intraocular lens (T-IOL) can correct high corneal...

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    pub_type: 杂志文章,评审

    doi:10.1055/s-0029-1246046

    authors: Eppig T,Viestenz A,Seitz B,Langenbucher A

    更新日期:2011-08-01 00:00:00

  • [Lidloading and intraocular pressure].

    abstract:BACKGROUND:Implantation of rigid gold or platinum lid weights (lidloading) represents the most common method for therapy of patients with lagophthalmus as a result of facial palsy. In a more recent approach also flexible platinum chains have been used. Glaucoma has frequently been described as a contraindication for li...

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    pub_type: 杂志文章

    doi:10.1055/s-2004-813940

    authors: Schrom T,Habermann A,Wernecke K,Scherer H,Duncker G

    更新日期:2005-01-01 00:00:00

  • [Clinically unsuspected malignant melanomas of the posterior uvea (author's transl)].

    abstract::Out of 1300 eyes enucleated between 1966-1974, 300 subsequently revealed histologically-proved malignant melanomas of the uvea. In 264 cases the clinical diagnosis was correctly made. In 36 cases the i.o. malignant melanomas were clinically unsuspected. The incorrect clinical diagnoses included: secondary glaucoma (30...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Völcker HE,Naumann GO

    更新日期:1976-03-01 00:00:00