Abstract:
:Prehypertension is associated with increased cardiovascular events. While the "tracking phenomenon" is an important longitudinal characteristic of blood pressure (BP), changes in muscle sympathetic nerve activity (MSNA) over time remain unclear. This study tested the hypothesis that MSNA tracking contributes to BP trends in prehypertension. BP and MSNA were assessed in 13 prehypertensive males at rest, during hand grip and mental stressors at baseline and after 8 years. Baseline office BP averaged 127 ± 2/81 ± 2 mmHg and MSNA 24 ± 4 bursts/min. BP increased by 7 ± 2/5 ± 2 mmHg (P < 0.01) and MSNA by 11 ± 2 bursts/min (P < 0.001) at follow-up. SBP and DBP were interrelated at baseline (r = 0.65, P = 0.02) and at follow-up (r = 0.78, P = 0.002). MSNA tracking (r = 0.82; P < 0.001) was similar to BP. MSNA was strongly related to DBP at baseline (r = 0.73; P < 0.01) and follow-up (r = 0.64; P = 0.01), more so than SBP. BMI increased (P < 0.001) at follow-up but was unrelated to BP or MSNA. Despite comparable pressor and cardiac increases to handgrip and mental stressors, sympathetic responses were blunted, more pronounced to isometric test (P < 0.006) at follow-up. In conclusion, the trend in MSNA corresponds with BP changes over time suggesting that tonic sympathetic activation may contribute to time-related increase in resting BP and the development of sustained hypertension in prehypertension.
journal_name
Blood Pressjournal_title
Blood pressureauthors
Hering D,Kara T,Kucharska W,Somers VK,Narkiewicz Kdoi
10.3109/08037051.2015.1121708subject
Has Abstractpub_date
2016-06-01 00:00:00pages
184-92issue
3eissn
0803-7051issn
1651-1999journal_volume
25pub_type
杂志文章相关文献
BLOOD PRESSURE文献大全abstract::BACKGROUND AND AIM. The ratio of deceleration time to early mitral wave velocity (mitral deceleration index, MDI) has been recently shown to predict cardiovascular events more precisely than deceleration time alone in human hypertension. Data, however, about the relationship of this parameter with cardiac structure ar...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2011.553926
更新日期:2011-08-01 00:00:00
abstract::Treatment with angiotensin-converting enzyme (ACE) inhibitors is frequently associated with persistent dry cough. This side effect is thought to be due to the non-specific action of ACE inhibitors, which, in addition to suppressing the renin-angiotensin system (RAS), leads to the accumulation of kinins, encephalins an...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370500439290
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Essential hypertension and insulin resistance frequently coexist; cyclosporine A (CsA) is known to induce hypertension which has been used as a model for essential hypertension. The present study aimed to evaluate whether elevated blood pressure and insulin resistance coexist during CsA therapy to prove the ...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章
doi:10.3109/08037059709086440
更新日期:1997-01-01 00:00:00
abstract::Plasma level of adrenaline has been reported to be elevated in borderline hypertension. However, its role in developing and maintaining hypertension is still not completely understood. This study aimed to estimate the role of plasma adrenaline in developing hypertension. Ten patients with borderline hypertension (BHT)...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059509077578
更新日期:1995-03-01 00:00:00
abstract::BACKGROUND. Ganglioneuromas (GNs) are neural crest cell-derived tumors and rarely occur in the adrenal gland. They are usually asymptomatic and hormonally silent. The majority of cases are detected incidentally during work-up for unrelated conditions. Hormone-secreting pure adrenal GNs in adults are extremely rare. To...
journal_title:Blood pressure
pub_type: 杂志文章,评审
doi:10.3109/08037051.2013.796103
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:Hypertension is a significant contributor to cardiovascular disease in HIV-infected individuals. The purposes of this study were to assess the development of new-onset hypertension and the use of antihypertensive treatment and blood pressure (BP) control. METHODS:In a longitudinal study of 434 HIV-infected ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2012.680742
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:High normal blood pressure (HNBP), i.e. blood pressure (BP) > or = 130/85 mmHg and <140/90 mmHg, is an important predictor of progression to established hypertension. DESIGN:The purpose of this retrospective study was the evaluation of the predictive value of ambulatory blood pressure monitoring (ABPM) for ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050410021414
更新日期:2004-01-01 00:00:00
abstract::Atherosclerosis is characterized by hypertrophy of the vascular media, intimal thickening and lipid-containing plaques. Atherosclerosis is a progressive systemic vascular disease which leads to impaired tissue perfusion due to vascular obstruction. In advanced stages it is often complicated by thrombosis. Recent resea...
journal_title:Blood pressure
pub_type: 杂志文章,评审
doi:10.3109/08037059409102274
更新日期:1994-09-01 00:00:00
abstract::The purpose: To evaluate longitudinal trends in the prevalence of hyperuricaemia and chronic kidney disease (CKD) in Czech adults with and without arterial hypertension (HT).Materials and methods: Two independent cross-sectional surveys were performed in 2006-2009 and 2015-2018, each screening involving 1% population ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037051.2020.1763158
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The lack of nocturnal BP fall less than 10% of the daytime, called non-dipper hypertension, is associated with increased cardiovascular morbidity and mortality. The aim of our study was to investigate atrial conduction time in patients with non-dipper hypertension using electromechanical coupling interval an...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2010.532302
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To determine the clinical profile and blood pressure (BP) control rates of anticoagulated patients with hypertension and atrial fibrillation (AF). METHODS:The PAULA study was a multicenter cross-sectional/retrospective observational study conducted throughout Spain. The study included patients with nonvalvul...
journal_title:Blood pressure
pub_type: 杂志文章,多中心研究
doi:10.1080/08037051.2017.1313094
更新日期:2017-10-01 00:00:00
abstract::Having found that circulating adrenaline (AD) is selectively elevated in stroke-prone spontaneously hypertensive rats (SHRSP) compared with Wistar-Kyoto rats (WKY), we extended the comparison to include other normotensive and hypertensive rat strains. Aortic catheters were implanted in young (5-7 weeks) and old (7-9 m...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059409101529
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Orthostatic hypotension (OH) is common amongst the older population and is associated with morbidity and mortality. We sought to investigate predictors of OH to assist the clinician in identifying patients at risk. METHODS AND RESULTS:Database of 2696 patients attending a transient ischaemic attack (TIA) cl...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2012.732780
更新日期:2013-04-01 00:00:00
abstract::Purpose: Previous studies that evaluated the prevalence of hypertension in Nigeria were either clinic based, non-standardized or did not include out-of-clinic blood pressure (BP) measurement. Materials and Methods: We selected a rural and an urban community in one state in each of the 6 geopolitical zones of Nigeria. ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037051.2019.1612706
更新日期:2019-08-01 00:00:00
abstract::It has previously been documented that patients with obstructive sleep apnoea (OSA) have an abnormal blood pressure (pressor) response to acute hypoxia when awake. The relationship between hypoxic chemosensitivity and 24 h blood pressure in OSA is not known. Twenty-four hour ambulatory BP (ABP) was measured at 15 min ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059409101521
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND AND AIM:Weight and height are two major determinants of left ventricular mass (LVM); the anthropometric parameter to which LVM should be normalized remains, however, debated. In a population of hypertensives, we compared the prevalence of left ventricular hypertrophy (LVH) defined by two indexation criteria ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2010.506029
更新日期:2010-12-01 00:00:00
abstract::It has been reported that the number of circulating endothelial progenitor cells (EPCs) reflects the endogenous vascular repair ability, with the EPCs pool declining in the presence of cardiovascular risk factors. However, their relationship with hypertension and the effects of anti-hypertensive treatment remain uncle...
journal_title:Blood pressure
pub_type: 杂志文章,随机对照试验
doi:10.3109/08037051.2010.535973
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:There are controversial results regarding the endothelial function in patients with white coat hypertension (WCH). The aim of this study was to assess endothelial function measuring nitric oxide (NO) and C-reactive protein (CRP) level in WCH and to compare those with essential hypertension (EH) and healthy s...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2011.649541
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:To compare the effects of amlodipine and candesartan on oxidized low-density lipoprotein (OxLDL), conjugated dienes (CD) and baseline diene conjugation in circulating low-density lipoproteins (LDL-BDC) level during antihypertensive treatment. METHODS:Forty-nine patients with untreated mild to moderate essent...
journal_title:Blood pressure
pub_type: 杂志文章,随机对照试验
doi:10.1080/08037050601037844
更新日期:2006-01-01 00:00:00
abstract::NORDIL--the Nordic Diltiazem Study (NORDIL)--is a prospective, randomized, open blinded-endpoint (PROBE), multicenter, parallel-group morbidity/mortality outcome study in hypertensive patients designed to compare an intervention strategy based on the calcium antagonist diltiazem with a strategy based on conventional a...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1080/080370599439517
更新日期:1999-01-01 00:00:00
abstract::Purpose: To study the differences in attitudes towards hypertension and drug treatment between patients persistent and non-persistent to antihypertensive drug treatment. Materials and methods: Cross-sectional study on patients with hypertension treated at 25 primary healthcare centres in Stockholm, Sweden. Questionnai...
journal_title:Blood pressure
pub_type: 杂志文章,多中心研究
doi:10.1080/08037051.2019.1627858
更新日期:2019-10-01 00:00:00
abstract:AIM:The purpose of this study was to evaluate the prevalence of home blood pressure (BP) measurement, the type of devices and accuracy in a large sample of hypertensive patients referred to hospital outpatient hypertension clinics. METHODS:Eight hundred and fifty-five consecutive treated hypertensive patients who atte...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050500210765
更新日期:2005-01-01 00:00:00
abstract::The study explored the relationship between time- and frequency-domain indices of cardiac autonomic control and 24 h blood pressure variability (BPV) in a sample of healthy men and women. Vagally mediated cardiac control was inversely related to 24 h BPV, and measures of cardiac autonomic control were better predictor...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2016.1090721
更新日期:2016-01-01 00:00:00
abstract::In this study we aimed to elucidate the role of central noradrenergic, dopaminergic, adrenergic and serotonergic neuronal systems in the development of essential hypertension. Fifteen untreated essential hypertensive subjects (aged 44 +/- 3 years) and 32 healthy volunteers (aged 38 +/- 3 years) participated in this st...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059409101522
更新日期:1994-03-01 00:00:00
abstract:AIMS:To assess safety and efficacy of valsartan/amlodipine combination in hypertensive Taiwanese patients. METHODS:This 12-week, multi-center, prospective, observational, post-marketing study enrolled 1029 patients to receive valsartan/amlodipine combination alone or as add-on to other antihypertensives. Efficacy was ...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究
doi:10.3109/08037051.2012.697629
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the prevalence and changes of cardiovascular risk factors in the middle-aged Lithuanian subjects after conducting the primary prevention program. DESIGN AND METHODS:Four cross-sectional investigations of cardiovascular risk factors were conducted in 2009 (n = 9625), 2010 ...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究
doi:10.3109/08037051.2014.961744
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES:We aimed to investigate left ventricular (LV) morphology and function in normotensive offspring of subjects with essential hypertension (familial trait - FT), and to determine the association between LV mass and determinants of LV diastolic function and endothelium-dependent (NO-mediated) dilation of the bra...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050701189941
更新日期:2007-01-01 00:00:00
abstract::Arterial hypertension is accompanied by increased morbidity and mortality and constitutes a substantial part of medical care. Antihypertensive intervention reduces the cardiovascular morbidity and mortality. The aims of the study were to evaluate the relationship between cardiovascular risk factors and the blood press...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050050151780
更新日期:2000-01-01 00:00:00
abstract::The aim of this study was to assess the associations between single nucleotide polymorphisms (SNPs) of the apelin and APJ (apelin receptor) genes and the risk of hypertension in people living in the south-east coastal area of China. A cross-sectional study involving 1031 participants was performed. Genotypes of the ap...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2016.1156905
更新日期:2016-08-01 00:00:00
abstract::Hypertensive patients who are at high risk of developing cardiovascular (CV) complications have become the focus of modern treatment guidelines. The choice of antihypertensive therapies in these patients should be evidence-based: in particular, there should be evidence of a beneficial impact on CV events in addition t...
journal_title:Blood pressure
pub_type: 杂志文章,评审
doi:10.1080/08037050211264
更新日期:2002-01-01 00:00:00