Abstract:
:The purpose: To evaluate longitudinal trends in the prevalence of hyperuricaemia and chronic kidney disease (CKD) in Czech adults with and without arterial hypertension (HT).Materials and methods: Two independent cross-sectional surveys were performed in 2006-2009 and 2015-2018, each screening involving 1% population random sample of the general population of nine districts of the Czech Republic aged 25-64 years, stratified by age and gender. Hyperuricaemia was defined as serum uric acid ≥ 420 μmol/l in men, and ≥ 360 μmol/l in women. CKD was defined as estimated glomerular filtration rate < 60 ml/min/1.73 m2 and/or albumin/creatinine ratio ≥ 3 mg/mmol.Results: Final analyses included 3504 individuals examined in 2006-2009, and 2309 in 2015-2018. The overall prevalence of hyperuricaemia increased from 16.4% to 25.2% in men (p < 0.001), and from 7.6% to 10.9% in women (p < 0.001), whereas the overall prevalence of CKD declined from 6.8% to 3.6% in men (p = 0.001), and from 7.6% to 4.8% in women (p < 0.001). There was no interaction between HT and hyperuricaemia in either gender; the increase in hyperuricaemia prevalence was observed both in hypertensive and normotensive adults and was accompanied by the increased prevalence of abdominal obesity. Contrarily, there was an interaction between HT and CKD in both men (p < 0.001) and women (p = 0.011); the CKD prevalence declined only in hypertensive individuals, specifically in those using antihypertensive medication and was accompanied by the increased use of renin-angiotensin-aldosterone system (RAS) inhibitors and calcium channel blockers (CCBs).Conclusions: Over the period of 10 years, the overall prevalence of hyperuricaemia increased, while the prevalence of CKD decreased. An increase in the prevalence of hyperuricaemia was observed both in hypertensive and normotensive individuals and was accompanied by an increase in the prevalence of abdominal obesity. A decline in the prevalence of CKD was only observed in hypertensive individuals and was accompanied by the increased use of RAS inhibitors and CCBs.
journal_name
Blood Pressjournal_title
Blood pressureauthors
Krajčoviechová A,Wohlfahrt P,Bruthans J,Šulc P,Lánská V,Borghi C,Cífková Rdoi
10.1080/08037051.2020.1763158subject
Has Abstractpub_date
2020-10-01 00:00:00pages
308-318issue
5eissn
0803-7051issn
1651-1999journal_volume
29pub_type
杂志文章相关文献
BLOOD PRESSURE文献大全abstract::Arterial hypertension is accompanied by increased morbidity and mortality and constitutes a substantial part of medical care. Antihypertensive intervention reduces the cardiovascular morbidity and mortality. The aims of the study were to evaluate the relationship between cardiovascular risk factors and the blood press...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050050151780
更新日期:2000-01-01 00:00:00
abstract::Low compliance to therapeutic regimens can have serious impact on patient health. A variety of technologies such as tablet dispensers and reminders has been developed to improve compliance. The aim of this study was to assess the acceptance of patients and physicians with regard to the functions and usefulness of a re...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037050903289598
更新日期:2009-01-01 00:00:00
abstract::We have previously shown that the angiotensin receptor blocker valsartan is associated with a lower incidence of new-onset type 2 diabetes than that with the calcium-channel antagonist amlodipine in the treatment of hypertensive patients at high cardiovascular risk. We have now investigated the benefits of valsartan v...
journal_title:Blood pressure
pub_type: 杂志文章,随机对照试验
doi:10.1080/08037050802169644
更新日期:2008-01-01 00:00:00
abstract::Treatment with angiotensin-converting enzyme (ACE) inhibitors is frequently associated with persistent dry cough. This side effect is thought to be due to the non-specific action of ACE inhibitors, which, in addition to suppressing the renin-angiotensin system (RAS), leads to the accumulation of kinins, encephalins an...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370500439290
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Hypertension is a significant contributor to cardiovascular disease in HIV-infected individuals. The purposes of this study were to assess the development of new-onset hypertension and the use of antihypertensive treatment and blood pressure (BP) control. METHODS:In a longitudinal study of 434 HIV-infected ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2012.680742
更新日期:2012-10-01 00:00:00
abstract::BACKGROUND. Ganglioneuromas (GNs) are neural crest cell-derived tumors and rarely occur in the adrenal gland. They are usually asymptomatic and hormonally silent. The majority of cases are detected incidentally during work-up for unrelated conditions. Hormone-secreting pure adrenal GNs in adults are extremely rare. To...
journal_title:Blood pressure
pub_type: 杂志文章,评审
doi:10.3109/08037051.2013.796103
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To determine the clinical profile and blood pressure (BP) control rates of anticoagulated patients with hypertension and atrial fibrillation (AF). METHODS:The PAULA study was a multicenter cross-sectional/retrospective observational study conducted throughout Spain. The study included patients with nonvalvul...
journal_title:Blood pressure
pub_type: 杂志文章,多中心研究
doi:10.1080/08037051.2017.1313094
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To investigate if young normotensive subjects with a familial history of essential hypertension (FHH) or young borderline-hypertensive (BHT) subjects have a defect endothelial function. METHODS:Fifteen young (26 +/- 4 years) healthy normotensive (115 +/- 8/71 +/- 6 mmHg) subjects with a FHH, 31 matched healt...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370502320779485
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The clinical effects of percutaneous transluminal renal artery angioplasty (PTRA) in patients with renal vascular stenosis and hypertension is controversial. METHODS:We consecutively recruited all 23 patients referred for evaluation of renovascular hypertension that eventually underwent unilateral PTRA, to ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050500339275
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:Compare multiple in office BP measurements in adolescents using an oscillometric device with out-of-office blood pressure measurements (home blood pressure monitoring - HBPM). MATERIALS AND METHODS:Office measurements were performed with validated semi-automatic devices twice (3 minutes interval) in two differ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037051.2017.1312279
更新日期:2017-10-01 00:00:00
abstract::It has been reported that the number of circulating endothelial progenitor cells (EPCs) reflects the endogenous vascular repair ability, with the EPCs pool declining in the presence of cardiovascular risk factors. However, their relationship with hypertension and the effects of anti-hypertensive treatment remain uncle...
journal_title:Blood pressure
pub_type: 杂志文章,随机对照试验
doi:10.3109/08037051.2010.535973
更新日期:2011-04-01 00:00:00
abstract::The purpose of this study was to test the hypothesis of a causal relationship between high insulin levels and the development of benign prostatic hyperplasia (BPH) and to determine the clinical, anthropometric, metabolic and insulin profile in men with fast-growing BPH compared with men with slow-growing BPH. The pres...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370599438365
更新日期:1999-01-01 00:00:00
abstract::Gestational hypertension is a recognized risk factor for the development of complications during pregnancy. The present study retrospectively assessed the respective values of blood pressure components derived from conventional and 24-h recordings (ABPM) as predictors of premature delivery in women with gestational hy...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050902836753
更新日期:2009-01-01 00:00:00
abstract::We wanted to investigate whether time to steady state was reached within 2 h of insulin infusion during isoglycemic hyperinsulinemic clamp, comparing the glucose uptake index (M/IG) with Bergman's insulin sensitivity index (Sip). We performed a 2-h oral glucose tolerance test and a 3-h isoglycemic hyperinsulinemic cla...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章
doi:10.1080/080370599439580
更新日期:1999-01-01 00:00:00
abstract::In order to study the role of opioid receptors in two models of experimental hypertension the binding of 3H-naloxone to membranes prepared from discrete brain regions and spinal cord was determined. Renal hypertensive rats (RHR) were found to have a greater density of 3H-naloxone binding sites in the hippocampus and h...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059409102254
更新日期:1994-05-01 00:00:00
abstract::Serum uric acid (SUA) but also hemorheological parameters such as hematocrit (Hct) and whole blood viscosity (WBV) are markers of cardiovascular risk. Increased blood cell volume is one of the known causes of hyperuricemia. We therefore aimed to investigate the relationship between SUA and hemorheology in untreated bo...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::In a sample comprising 51 normotensive subjects and 51 subjects with in-clinic arterial hypertension [blood pressures (BPs) > or = 140/90 mmHg), we investigated the prevalence of target organ damage [left ventricular hypertrophy (LVH) and retinal vasculopathy] in white coat hypertension (WCH) groups defined using: (a)...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370502760050377
更新日期:2002-01-01 00:00:00
abstract::An estimate of arterial compliance--the stroke volume/pulse pressure ratio (SV/PP)--was studied in 801 participants in the Tecumseh Blood Pressure Study, a population-based ongoing cardiovascular, epidemiological investigation. The subjects were normal young adults (mean age 30 +/- 5.6 years) and 373 were females. Car...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059209065121
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the prevalence and changes of cardiovascular risk factors in the middle-aged Lithuanian subjects after conducting the primary prevention program. DESIGN AND METHODS:Four cross-sectional investigations of cardiovascular risk factors were conducted in 2009 (n = 9625), 2010 ...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究
doi:10.3109/08037051.2014.961744
更新日期:2015-02-01 00:00:00
abstract::In order to study the contribution of the nitric oxide (NO)-pathway to cholinergic vasodilatation in the resistance vessels of the human forearm, we infused acetylcholine (ACh; 0.1 1000 ng/kg/min) or methacholine (MCh; 0.1 A 100 ng/kg/min) in the presence of saline, the NO-scavenger and guanylate cyclase inhibitor met...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059609078071
更新日期:1996-11-01 00:00:00
abstract::To investigate if increased lipid peroxidation is involved in hypercholesterolemia-induced hypertension and renal injury, we examined the effects of allopurinol, a xanthine oxidase inhibitor, on these conditions. Groups of male Sprague--Dawley rats were fed for 8 weeks with a high-cholesterol diet (4% cholesterol), a ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050510008878
更新日期:2005-01-01 00:00:00
abstract::Low birth weight and high placental weight are associated with increased cardiovascular morbidity and mortality. Children born after hypertensive pregnancies have higher blood pressure than children born after normotensive pregnancies. Hypertension in pregnancy is considered a major risk factor for intrauterine growth...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059609078060
更新日期:1996-09-01 00:00:00
abstract::We examined the influence of the Q89R variant in low-density lipoprotein receptor-related protein 5 on hypertension in a large Japanese cohort. We used multivariate logistic regression analysis to adjust for the effects of other factors known to influence hypertension such as age, body mass index, blood chemistry and ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050600650191
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:To characterize further the different reflected waves visible at the peripheral arterial pressure waveform, we recorded changes in the pulse wave contour during different stressful interventions. METHODS:Ten young healthy volunteers underwent two protocols. At the first occasion, the digital arterial pressu...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050310015962
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Endothelial dysfunction plays a major role in erectile dysfunction (ED). Uric acid (UA) is a marker of endothelial dysfunction. We hypothesized that increased UA levels may be associated with ED and aimed to investigate whether there is a relationship between, UA and ED in hypertensive patients. METHODS:A t...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2014.933032
更新日期:2014-12-01 00:00:00
abstract::Northern Africans constitute one of the largest immigrant groups in France; however, limited data are available on their cardiovascular risk factors. We carried out a retrospective cross-sectional study in a French hypertension unit, comparing 719 patients born in Northern Africa to 3558 controls born in Europe, indiv...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037050903464741
更新日期:2010-04-01 00:00:00
abstract::Abstract Background. The relationship between the C-344T polymorphism of CYP11b2 gene and blood pressure (BP) is controversial. The present study aimed to investigate whether it was affected by environmental determinants in Chinese Mongolian population. Methods. A cross-sectional study was conducted between 2003 and 2...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2010.495859
更新日期:2010-12-01 00:00:00
abstract::NORDIL--the Nordic Diltiazem Study (NORDIL)--is a prospective, randomized, open blinded-endpoint (PROBE), multicenter, parallel-group morbidity/mortality outcome study in hypertensive patients designed to compare an intervention strategy based on the calcium antagonist diltiazem with a strategy based on conventional a...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1080/080370599439517
更新日期:1999-01-01 00:00:00
abstract::Prehypertension is associated with increased cardiovascular events. While the "tracking phenomenon" is an important longitudinal characteristic of blood pressure (BP), changes in muscle sympathetic nerve activity (MSNA) over time remain unclear. This study tested the hypothesis that MSNA tracking contributes to BP tre...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2015.1121708
更新日期:2016-06-01 00:00:00
abstract::Sympathetic nerve activity is augmented by calcium-channel blocker treatment as a result of decreased blood pressure. Dihydropyridine calcium-channel blockers are divided into three different types. The purpose of the present study was to investigate whether treatment effects on hemodynamics, cardiac autonomic nerve a...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/08037051.2012.694200
更新日期:2012-12-01 00:00:00