Blood pressure level and relation to other cardiovascular risk factors in male hypertensive patients without clinical evidence of ischemic heart disease.

Abstract:

:Arterial hypertension is accompanied by increased morbidity and mortality and constitutes a substantial part of medical care. Antihypertensive intervention reduces the cardiovascular morbidity and mortality. The aims of the study were to evaluate the relationship between cardiovascular risk factors and the blood pressure (BP), and to evaluate the percentage of patients who had achieved a BP level as recommended by the sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI). BP was evaluated in relation to age, body mass index, duration of hypertension, cholesterol and triglyceride level, smoking status, information of regular exercise, a family history of ischemic heart disease (IHD) and drug treatment, in 220 men treated for arterial hypertension. In the univariate analyses we found a higher systolic blood pressure (SBP) with older age, higher SBP in smoking patients and lower SBP in patients with regular exercise. In a multivariate model age (p = 0.0004), smoking status (p = 0.01) and regular exercise (p= 0.06) were independently associated with SBP. There was a lower diastolic blood pressure (DBP) with older age, and age was independently associated with DBP. Office SBP was above 140 mmHg in 83% and above 160 mmHg in 44% of patients. During ambulatory blood pressure monitoring (AMBP), SBP was above 135 mmHg in 40% and above 155 mmHg in 15% of patients. In addition to male sex and hypertension there was a high percentage of other cardiovascular risk factors--43% was smoking, 21% had a family history of IHD, 77% had a se-cholesterol above 5.5 mmol/l and 48% had a se-triglyceride above 1.6 mmol/l. In a consecutive group of asymptomatic male treated hypertensive patients SBP is independently associated with age and smoking status, and DBP with age. A high percentage of the patients do not have a well controlled BP, and a high percentage have additional risk factors such as smoking, hypercholesterolaemia, hypertriglyceridaemia and a family history of IHD. This means that there is room for much improvement in the control of hypertension.

journal_name

Blood Press

journal_title

Blood pressure

authors

Larsen CT,Sørum C,Hansen JF,Jensen HA,Rasmussen V

doi

10.1080/08037050050151780

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

91-7

issue

2-3

eissn

0803-7051

issn

1651-1999

journal_volume

9

pub_type

杂志文章
  • A comparison of spirapril and isradipine in patients with diabetic nephropathy and hypertension.

    abstract::The effects of spirapril and isradipine on blood pressure, urinary albumin excretion and sodium-volume homeostasis in hypertensive insulin-dependent diabetic patients with nephropathy were assessed. Fifteen Type 1 diabetic patients aged 28-53 years with a diabetes duration of 19-37 years were studied. All had hyperten...

    journal_title:Blood pressure

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/08037059309077172

    authors: Nørgaard K,Jensen T,Christensen P,Feldt-Rasmussen B

    更新日期:1993-12-01 00:00:00

  • Exercise systolic blood pressure at moderate workload predicts cardiovascular disease and mortality through 35 years of follow-up in healthy, middle-aged men.

    abstract:OBJECTIVE:There is an association between exercise systolic blood pressure (SBP) and cardiovascular disease and mortality. The aim of this study was to investigate this association, with 35 years of follow-up. METHODS:Through 1972-75, 2014 healthy, middle-aged men underwent thorough medical examination and a bicycle e...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/08037051.2017.1291276

    authors: Mariampillai JE,Engeseth K,Kjeldsen SE,Grundvold I,Liestøl K,Erikssen G,Erikssen J,Bodegard J,Skretteberg PT

    更新日期:2017-08-01 00:00:00

  • Vascular stiffness and endothelial dysfunction: Correlations at different levels of blood pressure.

    abstract:UNLABELLED:Resistant hypertensive (RHTN) patients have endothelial dysfunction and aldosterone excess, which contribute to the development of resistance to antihypertensive treatment and cardiovascular complications. Biophysical forces within the arterial wall provide functional regulation of arterial stiffness. Caroti...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037051.2011.617045

    authors: Figueiredo VN,Yugar-Toledo JC,Martins LC,Martins LB,de Faria AP,de Haro Moraes C,Sierra C,Coca A,Moreno H

    更新日期:2012-02-01 00:00:00

  • Effects of nebivolol and atenolol on central aortic pressure in hypertensive patients: a multicenter, randomized, double-blind study.

    abstract:INTRODUCTION:The main objective was to compare the mean change in augmentation index of hypertensive patients treated with nebivolol or atenolol. METHODS:Multicenter, double-blind randomized study conducted in six Spanish centers. We enrolled outpatients between the ages of 40 and 65 years with mild or moderate essent...

    journal_title:Blood pressure

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3109/08037051.2013.840421

    authors: Redón J,Pascual-Izuel JM,Rodilla E,Vicente A,Oliván J,Bonet J,Torguet JP,Calaforra O,Almirall J

    更新日期:2014-06-01 00:00:00

  • Purification of class I medullipins from the venous effluent of isolated normal kidneys perfused under high pressure with saline.

    abstract::Medullipin I (Med I) is a vasodepressor prohormone which is continuously elaborated into the renal venous effluent (RVE) of isolated rat kidneys perfused under high pressure. We have improved the yield of Med I by substituting saline for the albumin perfusate previously reported; and considerably improved refinement b...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037059409102295

    authors: Brooks B,Byers LW,Muirhead EE,Muirhead M,Pitcock JA,Maddipati KR,Maxey KM

    更新日期:1994-11-01 00:00:00

  • Post-marketing surveillance study of valsartan/amlodipine combination in Taiwanese hypertensive patients.

    abstract:AIMS:To assess safety and efficacy of valsartan/amlodipine combination in hypertensive Taiwanese patients. METHODS:This 12-week, multi-center, prospective, observational, post-marketing study enrolled 1029 patients to receive valsartan/amlodipine combination alone or as add-on to other antihypertensives. Efficacy was ...

    journal_title:Blood pressure

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.3109/08037051.2012.697629

    authors: Cheng SM,Mar GY,Huang SC,Chen CS,Hsieh CM,Huang LC,Ueng KC

    更新日期:2012-07-01 00:00:00

  • Effects of normal blood pressure, prehypertension and hypertension on left ventricular diastolic function and aortic elastic properties.

    abstract:BACKGROUND:The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (BP) provides guideline for the new category of BP levels as normal, prehypertension (PHT), and hypertension. Although PHT is associated with a markedly increased risk of developing h...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/08037050701395910

    authors: Erdogan D,Caliskan M,Yildirim I,Gullu H,Baycan S,Ciftci O,Yildirir A,Muderrisoglu H

    更新日期:2007-01-01 00:00:00

  • Left ventricular hypertrophy detection and body mass index in essential hypertension.

    abstract:BACKGROUND AND AIM:Weight and height are two major determinants of left ventricular mass (LVM); the anthropometric parameter to which LVM should be normalized remains, however, debated. In a population of hypertensives, we compared the prevalence of left ventricular hypertrophy (LVH) defined by two indexation criteria ...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037051.2010.506029

    authors: Cuspidi C,Giudici V,Lonati L,Sala C,Valerio C,Mancia G

    更新日期:2010-12-01 00:00:00

  • The effect of coronary angioplasty on plasma NT-proBNP level in patients with and without arterial hypertension.

    abstract:AIMS:The purpose of the study was to assess the effect of percutaneous transluminal coronary angioplasty (PTCA) on plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) level in hypertensive and normotensive subjects with and without systolic left ventricular dysfunction. METHODS AND RESULTS:Forty patients affec...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/08037050600804814

    authors: Brzezinska U,El Mokhtari NE,Simon R,Tykarski A

    更新日期:2006-01-01 00:00:00

  • White coat hypertension and carotid atherosclerosis.

    abstract::To investigate further the relationship between atherosclerotic vascular disease and blood pressure, and the phenomenon of white coat hypertension, we performed a cross-sectional study of patients referred for carotid Doppler scanning, to determine the relationship between ambulatory blood pressure monitoring (ABPM) a...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/080370599439652

    authors: Landray MJ,Sagar G,Murray S,Beevers M,Beevers DG,Lip GY

    更新日期:1999-01-01 00:00:00

  • The stroke preventive effect in elderly hypertensives cannot fully be explained by the reduction in office blood pressure--insights from the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension).

    abstract:OBJECTIVE:To study whether the cardiovascular preventive effect of antihypertensive therapy can be explained solely by the reduction in office blood pressure, and to what extent the risk of stroke and cardiac events is associated with in-study diastolic blood pressure (DBP) and systolic blood pressure (SBP). DESIGN:Th...

    journal_title:Blood pressure

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.3109/08037059209077513

    authors: Ekbom T,Dahlöf B,Hansson L,Lindholm LH,Odén A,Scherstén B,Wester PO

    更新日期:1992-10-01 00:00:00

  • Longitudinal tracking of muscle sympathetic nerve activity and its relationship with blood pressure in subjects with prehypertension.

    abstract::Prehypertension is associated with increased cardiovascular events. While the "tracking phenomenon" is an important longitudinal characteristic of blood pressure (BP), changes in muscle sympathetic nerve activity (MSNA) over time remain unclear. This study tested the hypothesis that MSNA tracking contributes to BP tre...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037051.2015.1121708

    authors: Hering D,Kara T,Kucharska W,Somers VK,Narkiewicz K

    更新日期:2016-06-01 00:00:00

  • The Bergen Blood Pressure Study: inappropriately low levels of circulating atrial natriuretic peptide in offspring of hypertensive families.

    abstract::Plasma atrial natriuretic peptide (ANP), plasma and 24-h urine catecholamines, plasma renin activity (PRA), and serum aldosterone were studied in offspring of hypertensive and normotensive families [n = 82; age 37 +/- 7 years (mean +/- SD)]. Despite higher age, higher blood pressure, and higher urine excretion of cate...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037059409102261

    authors: Mo R,Myking OL,Lund-Johansen P,Omvik P

    更新日期:1994-07-01 00:00:00

  • Marked hepatotoxicity associated with losartan treatment.

    abstract::Losartan represent a novel approach in the treatment of hypertension. Clinical trials have reported a very low incidence of side effects. We describe two patients who developed increases in alanine/aspartate amino transferase of 8 and 15 times the upper normal limit, as well as thoracic pain, after a short time of tre...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037059609062128

    authors: Nygaard B,Strandgaard S

    更新日期:1996-05-01 00:00:00

  • Predictors of orthostatic hypotension in patients attending a transient ischaemic attack clinic: database study.

    abstract:BACKGROUND:Orthostatic hypotension (OH) is common amongst the older population and is associated with morbidity and mortality. We sought to investigate predictors of OH to assist the clinician in identifying patients at risk. METHODS AND RESULTS:Database of 2696 patients attending a transient ischaemic attack (TIA) cl...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037051.2012.732780

    authors: de la Iglesia B,Ong AC,Potter JF,Metcalf AK,Myint PK

    更新日期:2013-04-01 00:00:00

  • Effectiveness of hypertension treatment assessed by blood pressure level achieved in primary care setting in Poland.

    abstract::The effectiveness of hypertension treatment remains low in many developed countries. The aim of our study was to evaluate the treatment effectiveness in hypertensives treated by general practitioners (GPs) in Poland. Twenty thousand three hundred and five hypertensive patients (mean age 60.1 +/- 12.0 years, 9918 women...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/08037050310015458

    authors: Grzybowski A,Bellwon J,Gruchała M,Stolarczyk L,Popaszkiewicz J,Sobiczewski W,Rynkiewicz A

    更新日期:2003-01-01 00:00:00

  • The Bergen Blood Pressure Study: definition of hypertensive and normotensive families based on 27 years' follow-up.

    abstract::The familial aggregation of hypertension is well documented. However, many studies on the familial predisposition have suffered from insufficient knowledge of parental blood pressure (BP). In the present study, the family history is defined according to parental data from two BP surveys conducted almost 30 years apart...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037059209077668

    authors: Mo R,Lund-Johansen P,Omvik P

    更新日期:1992-12-01 00:00:00

  • Ambulatory monitoring predicts development of drug-treated hypertension in subjects with high normal blood pressure.

    abstract:BACKGROUND:High normal blood pressure (HNBP), i.e. blood pressure (BP) > or = 130/85 mmHg and <140/90 mmHg, is an important predictor of progression to established hypertension. DESIGN:The purpose of this retrospective study was the evaluation of the predictive value of ambulatory blood pressure monitoring (ABPM) for ...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/08037050410021414

    authors: Pannarale G,Gaudio C,Mirabelli F,Monti F,Franchitto S,Di Michele S,Puddu PE,Fedele F

    更新日期:2004-01-01 00:00:00

  • Proximal renal tubular pressure-natriuresis-relation in essential hypertensives following acute vasodilatation.

    abstract::Blood pressure (BP) and excretory function including lithium clearance were investigated during water-loading and constant infusion of 131I-hippuran and 125I-iothalamate for measurement of renal haemodynamics in 8 untreated essential hypertensives (mean BP +/- SD: 169 +/- 14/107 +/- 6 mmHg) before and after vasodilata...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037059309077525

    authors: Krusell LR,Jespersen LT,Thomsen K,Pedersen OL

    更新日期:1993-03-01 00:00:00

  • Central hemodynamics in relation to low-level environmental lead exposure.

    abstract::Purpose: Arterial stiffness predicts cardiovascular complications. The association between arterial stiffness and blood lead (BL) remains poorly documented. We aimed to assess the association of central hemodynamic measurements, including pulse wave velocity (aPWV), with blood lead in a Flemish population.Materials an...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/08037051.2019.1658518

    authors: Yu CG,Wei FF,Zhang ZY,Thijs L,Yang WY,Mujaj B,Feng YM,Boggia J,Roels HA,Struijker-Boudier HAJ,Nawrot TS,Verhamme P,Staessen JA

    更新日期:2020-06-01 00:00:00

  • Intraplatelet free calcium concentrations and alcohol-related blood pressure elevation in a middle-aged male population.

    abstract::Elevated intracellular free calcium (Ca2+) has been proposed as a mechanism of alcohol-induced hypertension from animal experimental studies, but this has not been confirmed in man. In the present study, intraplatelet Ca2+ concentration (plt.[Ca2+]i) was measured in 83 middle-aged men, and the associations between alc...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037059509077576

    authors: Ikai E,Ishizaki M,Tsuritani I,Ishida M,Noborisaka Y,Yamada Y

    更新日期:1995-03-01 00:00:00

  • Unattended versus two attended, ambulatory and central blood pressure measurements in hypertensive patients with and without diabetes.

    abstract:OBJECTIVE:To compare unattended blood pressure (BP) with two attended BP, with 24-h ambulatory (ABPM) and central BP measurements in hypertensive patients with (DMs) and without diabetes (HTs). METHODS:In the same hypertension clinic we evaluate 129 consecutive HTs (56% female, 59 + 16 yrs) and 91 DMs (62% female, 64 ...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/08037051.2019.1568184

    authors: Polonia J,Baptista C,Silva J,Barbosa L

    更新日期:2019-04-01 00:00:00

  • The relationship between uric acid and erectile dysfunction in hypertensive subjects.

    abstract:BACKGROUND:Endothelial dysfunction plays a major role in erectile dysfunction (ED). Uric acid (UA) is a marker of endothelial dysfunction. We hypothesized that increased UA levels may be associated with ED and aimed to investigate whether there is a relationship between, UA and ED in hypertensive patients. METHODS:A t...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037051.2014.933032

    authors: Aribas A,Kayrak M,Ulucan S,Keser A,Demir K,Alibasic H,Akilli H,Solak Y,Avci A,Turan Y,Kaya Z,Katlandur H,Kanbay M

    更新日期:2014-12-01 00:00:00

  • Beta-adrenergic blocking drugs in the treatment of hypertension.

    abstract::The reduction in blood pressure seen with the use of beta-blocking drugs was an unexpected finding. Initially there was resistance to their use as the reduction of cardiac output and increase in peripheral resistance from beta-blockade was considered an undesirable pharmacological action for a drug in the treatment of...

    journal_title:Blood pressure

    pub_type: 杂志文章,评审

    doi:10.1080/080370501753400665

    authors: Prichard BN,Cruickshank JM,Graham BR

    更新日期:2001-01-01 00:00:00

  • How accurate are hypertension treatment decisions? Absolute risk assessment and prescribing for moderate hypertension--a study of Cambridge general practitioners.

    abstract:OBJECTIVE:To determine the factors influencing general practitioners' prescribing for patients with moderate hypertension, and to investigate their ability to assess patients' absolute risk of cardiovascular disease. DESIGN:Decision-making was assessed by a postal questionnaire involving five standardised example pati...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/080370500300000897

    authors: Hamilton-Craig CR,Tonkin AL,Jobling RG

    更新日期:2000-01-01 00:00:00

  • Comparison of cholinergic vasodilator responses to acetylcholine and methacholine in the human forearm.

    abstract::In order to study the contribution of the nitric oxide (NO)-pathway to cholinergic vasodilatation in the resistance vessels of the human forearm, we infused acetylcholine (ACh; 0.1 1000 ng/kg/min) or methacholine (MCh; 0.1 A 100 ng/kg/min) in the presence of saline, the NO-scavenger and guanylate cyclase inhibitor met...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.3109/08037059609078071

    authors: Bruning TA,Chang PC,Kemme MJ,Vermeij P,Pfaffendorf M,van Zwieten PA

    更新日期:1996-11-01 00:00:00

  • Arterial hypertension, left ventricular geometry and QT dispersion in a middle-aged Estonian female population.

    abstract::The aim of the present study was to determine the prevalence of Left ventricular hypertrophy (LVH) and different left ventricular (LV) geometric patterns in the middle-aged women population of Tallinn, to assess the relationship between LV geometry, age, blood pressure and LV repolarization duration and inhomogeneity....

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:

    authors: Shipilova T,Pshenichnikov I,Kaik J,Volozh O,Abina J,Kalev M,Lass J,Karai D

    更新日期:2003-01-01 00:00:00

  • Removing the mask on hypertension (REMAH) study: Design; quality of blood pressure phenotypes and characteristics of the first 490 participants.

    abstract::Purpose: Previous studies that evaluated the prevalence of hypertension in Nigeria were either clinic based, non-standardized or did not include out-of-clinic blood pressure (BP) measurement. Materials and Methods: We selected a rural and an urban community in one state in each of the 6 geopolitical zones of Nigeria. ...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/08037051.2019.1612706

    authors: Nwakile PC,Chori BS,Danladi B,Umar A,Okoye IC,Nwegbu M,Zawaya K,Essien I,Sada K,Ogedengbe J,Aje A,Isiguzo G,Odili AN

    更新日期:2019-08-01 00:00:00

  • The effect of percutaneous dilatation of renal arterial stenosis on captopril renography in hypertension.

    abstract:BACKGROUND:The clinical effects of percutaneous transluminal renal artery angioplasty (PTRA) in patients with renal vascular stenosis and hypertension is controversial. METHODS:We consecutively recruited all 23 patients referred for evaluation of renovascular hypertension that eventually underwent unilateral PTRA, to ...

    journal_title:Blood pressure

    pub_type: 杂志文章

    doi:10.1080/08037050500339275

    authors: Anfelter P,Granerus G,Stenström H,Eriksson P,Nyström FH

    更新日期:2005-01-01 00:00:00

  • Obstructive sleep apnea and blood pressure elevation: what is the relationship? Working Group on OSA and Hypertension.

    abstract::Sleep disordered breathing has increasingly been recognised as a frequent cause of ill-health in the community. Moderate or severe forms of the most common condition, obstructive sleep apnea (OSA), occur in up to 12% of the adult male population. A substantial body of literature has been published on the potential rel...

    journal_title:Blood pressure

    pub_type: 杂志文章,评审

    doi:10.3109/08037059309077548

    authors:

    更新日期:1993-09-01 00:00:00