Marked hepatotoxicity associated with losartan treatment.

abstract：:Plasma atrial natriuretic peptide (ANP), plasma and 24-h urine catecholamines, plasma renin activity (PRA), and serum aldosterone were studied in offspring of hypertensive and normotensive families [n = 82; age 37 +/- 7 years (mean +/- SD)]. Despite higher age, higher blood pressure, and higher urine excretion of cate...

journal_title：Blood pressure

authors： Mo R,Myking OL,Lund-Johansen P,Omvik P

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:Hypertension is a significant contributor to cardiovascular disease in HIV-infected individuals. The purposes of this study were to assess the development of new-onset hypertension and the use of antihypertensive treatment and blood pressure (BP) control. METHODS:In a longitudinal study of 434 HIV-infected ...

journal_title：Blood pressure

authors： Manner IW,Baekken M,Oektedalen O,Os I

更新日期：2012-10-01 00:00:00

abstract：:Having found that circulating adrenaline (AD) is selectively elevated in stroke-prone spontaneously hypertensive rats (SHRSP) compared with Wistar-Kyoto rats (WKY), we extended the comparison to include other normotensive and hypertensive rat strains. Aortic catheters were implanted in young (5-7 weeks) and old (7-9 m...

journal_title：Blood pressure

authors： Jablonskis LT,Howe PR

更新日期：1994-03-01 00:00:00

abstract：:In a previous study we investigated the differential time courses of the vasodilator effect of various calcium antagonists (CA) in small isolated rat mesenteric arteries (van der Lee et al., Fundam Clin Pharmacol, 1998: 12: 607-12). We concluded that the differences observed could be due to differences in lipophilicit...

journal_title：Blood pressure

authors： van der Lee R,Pfaffendorf M,Koopmans RP,van Lieshout JJ,van Montfrans GA,van Zwieten PA

更新日期：2001-01-01 00:00:00

abstract：:It has been reported that the number of circulating endothelial progenitor cells (EPCs) reflects the endogenous vascular repair ability, with the EPCs pool declining in the presence of cardiovascular risk factors. However, their relationship with hypertension and the effects of anti-hypertensive treatment remain uncle...

journal_title：Blood pressure

authors： de Ciuceis C,Pilu A,Rizzoni D,Porteri E,Muiesan ML,Salvetti M,Paini A,Belotti E,Zani F,Boari GE,Rosei CA,Rosei EA

更新日期：2011-04-01 00:00:00

abstract：:Purpose: Elevated blood pressure induces electrocardiographic changes and is associated with an increase in cardiovascular disease later in life compared to normal blood pressure levels. The purpose of this study was to evaluate the association between normal to high normal blood pressure values (90-139/50-89 mmHg) an...

journal_title：Blood pressure

authors： Hassing GJ,van der Wall HEC,van Westen GJP,Kemme MJB,Adiyaman A,Elvan A,Burggraaf J,Gal P

更新日期：2020-04-01 00:00:00

abstract：:Northern Africans constitute one of the largest immigrant groups in France; however, limited data are available on their cardiovascular risk factors. We carried out a retrospective cross-sectional study in a French hypertension unit, comparing 719 patients born in Northern Africa to 3558 controls born in Europe, indiv...

journal_title：Blood pressure

authors： Lepoutre-Lussey C,Plouin PF,Steichen O

更新日期：2010-04-01 00:00:00

abstract：:To investigate if increased lipid peroxidation is involved in hypercholesterolemia-induced hypertension and renal injury, we examined the effects of allopurinol, a xanthine oxidase inhibitor, on these conditions. Groups of male Sprague--Dawley rats were fed for 8 weeks with a high-cholesterol diet (4% cholesterol), a ...

journal_title：Blood pressure

authors： Minami M,Ishiyama A,Takagi M,Omata M,Atarashi K

更新日期：2005-01-01 00:00:00

abstract：:We wanted to investigate whether time to steady state was reached within 2 h of insulin infusion during isoglycemic hyperinsulinemic clamp, comparing the glucose uptake index (M/IG) with Bergman's insulin sensitivity index (Sip). We performed a 2-h oral glucose tolerance test and a 3-h isoglycemic hyperinsulinemic cla...

journal_title：Blood pressure

authors： Olsen MH,Andersen UB,Wachtell K,Ibsen H,Dige-Petersen H

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The efficacy and safety of renin angiotensin aldosterone system blockers (RAASB's) if introduced immediately after renal transplantation have not been extensively investigated. METHODS:The medical charts of 142 kidney transplant recipients who received a RAASB in the early postoperative period and of 114 ma...

journal_title：Blood pressure

authors： Chatzikyrkou C,Eichler J,Karch A,Clajus C,Scurt FG,Ramackers W,Lehner F,Menne J,Haller H,Mertens PR,Schiffer M

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (BP) provides guideline for the new category of BP levels as normal, prehypertension (PHT), and hypertension. Although PHT is associated with a markedly increased risk of developing h...

journal_title：Blood pressure

authors： Erdogan D,Caliskan M,Yildirim I,Gullu H,Baycan S,Ciftci O,Yildirir A,Muderrisoglu H

更新日期：2007-01-01 00:00:00

abstract：:BACKGROUND AND AIM. The ratio of deceleration time to early mitral wave velocity (mitral deceleration index, MDI) has been recently shown to predict cardiovascular events more precisely than deceleration time alone in human hypertension. Data, however, about the relationship of this parameter with cardiac structure ar...

journal_title：Blood pressure

authors： Cuspidi C,Negri F,Sala C,Mancia G

更新日期：2011-08-01 00:00:00

abstract：:Patients with severe hypertension with retinoscopic bilateral papilloedema only are not classically regarded as having malignant hypertension (MHT). We have encountered 23 such patients between 1965-1993, whilst over a similar period we have seen 315 patients who fulfilled the conventional criteria for MHT with bilate...

journal_title：Blood pressure

authors： Lip GY,Beevers M,Dodson PM,Beevers DG

更新日期：1995-11-01 00:00:00

abstract：:Atherosclerosis is characterized by hypertrophy of the vascular media, intimal thickening and lipid-containing plaques. Atherosclerosis is a progressive systemic vascular disease which leads to impaired tissue perfusion due to vascular obstruction. In advanced stages it is often complicated by thrombosis. Recent resea...

journal_title：Blood pressure

authors： Wennmalm A

更新日期：1994-09-01 00:00:00

abstract：:Blood pressure (BP) and excretory function including lithium clearance were investigated during water-loading and constant infusion of 131I-hippuran and 125I-iothalamate for measurement of renal haemodynamics in 8 untreated essential hypertensives (mean BP +/- SD: 169 +/- 14/107 +/- 6 mmHg) before and after vasodilata...

journal_title：Blood pressure

authors： Krusell LR,Jespersen LT,Thomsen K,Pedersen OL

更新日期：1993-03-01 00:00:00

abstract：AIMS:Cardiovascular disease is the leading cause of mortality and morbidity in the western world and has reached epidemic proportions. The incidence of congestive heart failure (CHD) and hypertension is also rising rapidly in many of the affluent Arab nations and cardiovascular diseases continue to be a leading cause o...

journal_title：Blood pressure

authors： Bener A,al Suwaidi J,el-Menyar A,Gehani A

更新日期：2004-01-01 00:00:00

abstract：:Hypertensive patients who are at high risk of developing cardiovascular (CV) complications have become the focus of modern treatment guidelines. The choice of antihypertensive therapies in these patients should be evidence-based: in particular, there should be evidence of a beneficial impact on CV events in addition t...

journal_title：Blood pressure

authors： Ruilope LM

更新日期：2002-01-01 00:00:00

abstract：:Gestational hypertension is a recognized risk factor for the development of complications during pregnancy. The present study retrospectively assessed the respective values of blood pressure components derived from conventional and 24-h recordings (ABPM) as predictors of premature delivery in women with gestational hy...

journal_title：Blood pressure

authors： Liro M,Gasowski J,Wydra D,Grodzicki T,Emerich J,Narkiewicz K

更新日期：2009-01-01 00:00:00

abstract：UNLABELLED:Resistant hypertensive (RHTN) patients have endothelial dysfunction and aldosterone excess, which contribute to the development of resistance to antihypertensive treatment and cardiovascular complications. Biophysical forces within the arterial wall provide functional regulation of arterial stiffness. Caroti...

journal_title：Blood pressure

authors： Figueiredo VN,Yugar-Toledo JC,Martins LC,Martins LB,de Faria AP,de Haro Moraes C,Sierra C,Coca A,Moreno H

更新日期：2012-02-01 00:00:00

abstract：:NORDIL--the Nordic Diltiazem Study (NORDIL)--is a prospective, randomized, open blinded-endpoint (PROBE), multicenter, parallel-group morbidity/mortality outcome study in hypertensive patients designed to compare an intervention strategy based on the calcium antagonist diltiazem with a strategy based on conventional a...

journal_title：Blood pressure

authors： Hedner T

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To determine the clinical profile and blood pressure (BP) control rates of anticoagulated patients with hypertension and atrial fibrillation (AF). METHODS:The PAULA study was a multicenter cross-sectional/retrospective observational study conducted throughout Spain. The study included patients with nonvalvul...

journal_title：Blood pressure

authors： Barrios V,Escobar C,Prieto Valiente L,Lobos JM,Vargas-Ortega D,Polo J,Marin Montañés N

更新日期：2017-10-01 00:00:00

abstract：:In this study we aimed to elucidate the role of central noradrenergic, dopaminergic, adrenergic and serotonergic neuronal systems in the development of essential hypertension. Fifteen untreated essential hypertensive subjects (aged 44 +/- 3 years) and 32 healthy volunteers (aged 38 +/- 3 years) participated in this st...

journal_title：Blood pressure

authors： Lambert GW,Ferrier C,Kaye DM,Kalff V,Kelly MJ,Cox HS,Turner AG,Jennings GL,Esler MD

更新日期：1994-03-01 00:00:00

abstract：PURPOSE:Event-based clinical outcome trials have shown limited evidence to support guidelines recommendations to lower blood pressure (BP) to <130/80 mmHg in middle-aged and elderly hypertensive patients with diabetes mellitus or with general high cardiovascular (CV) risk. We addressed this issue by post-hoc analysing ...

journal_title：Blood pressure

authors： Olsen E,Holzhauer B,Julius S,Kjeldsen SE,Larstorp ACK,Mancia G,Mehlum MH,Mo R,Rostrup M,Søraas CL,Zappe D,Weber MA

更新日期：2021-01-06 00:00:00

abstract：:This 1-year, dose-titration, General Practitioner (GP) study compared efficacy, tolerability and safety of oral temocapril (10-40 mg once daily) with atenolol (25-100 mg once daily) in mild to moderate adult hypertensives (diastolic blood pressure (DBP) 95-114 mmHg). A 12-week dose-titration period, randomized 3:1 tem...

journal_title：Blood pressure

authors： Sierakowski B,Püchler K,Witte PU,Renneisen K,Delius W

更新日期：1997-07-01 00:00:00

abstract：:Sleep disordered breathing has increasingly been recognised as a frequent cause of ill-health in the community. Moderate or severe forms of the most common condition, obstructive sleep apnea (OSA), occur in up to 12% of the adult male population. A substantial body of literature has been published on the potential rel...

journal_title：Blood pressure

authors：

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:To investigate if young normotensive subjects with a familial history of essential hypertension (FHH) or young borderline-hypertensive (BHT) subjects have a defect endothelial function. METHODS:Fifteen young (26 +/- 4 years) healthy normotensive (115 +/- 8/71 +/- 6 mmHg) subjects with a FHH, 31 matched healt...

journal_title：Blood pressure

authors： Millgård J,Hägg A,Sarabi M,Lind L

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:There are controversial results regarding the endothelial function in patients with white coat hypertension (WCH). The aim of this study was to assess endothelial function measuring nitric oxide (NO) and C-reactive protein (CRP) level in WCH and to compare those with essential hypertension (EH) and healthy s...

journal_title：Blood pressure

authors： Guven A,Tolun F,Caliskan M,Ciftci O,Muderrisoglu H

更新日期：2012-10-01 00:00:00

abstract：:The aim of the present study was to determine the prevalence of Left ventricular hypertrophy (LVH) and different left ventricular (LV) geometric patterns in the middle-aged women population of Tallinn, to assess the relationship between LV geometry, age, blood pressure and LV repolarization duration and inhomogeneity....

journal_title：Blood pressure

authors： Shipilova T,Pshenichnikov I,Kaik J,Volozh O,Abina J,Kalev M,Lass J,Karai D

更新日期：2003-01-01 00:00:00

abstract：:There is compelling evidence to indicate an important role for increased local renin-angiotensin system activity in the pathogenesis of cardiac hypertrophy and heart failure. Resveratrol is a natural polyphenol that activates SIRT1, a novel cardioprotective and longevity factor having NAD(+)-dependent histone deacetyl...

journal_title：Blood pressure

authors： Biala A,Tauriainen E,Siltanen A,Shi J,Merasto S,Louhelainen M,Martonen E,Finckenberg P,Muller DN,Mervaala E

更新日期：2010-06-01 00:00:00

abstract：:The BBB study (Swedish for Behandla Blodtryck Bättre or Treat Blood Pressure Better) was a multicenter trial designed to investigate three aspects of antihypertensive treatment: i) Is it possible to lower the diastolic blood pressure further in "well-treated" hypertensive patients through intensified therapy? ii) Can ...

journal_title：Blood pressure

authors： Hannson L

更新日期：1994-07-01 00:00:00