Abstract：
:It is during gastrulation that the primordial germ layers are specified, embryonic axes become morphologically manifest, and the embryonic body plan begins to take shape. As morphogenetic movements push and pull nascent tissues into position within the gastrula, new interactions are established between neighboring cells and tissues. These interactions represent an emergent property within gastrulating embryos, and serve to regulate and promote ensuing morphogenesis that establishes the next set of cell/tissue contacts, and so on. Several recent studies demonstrate the critical roles of such interactions during gastrulation, including those between germ layers, along embryonic axes, and at tissue boundaries. Emergent tissue interactions result from - and result in - morphogen signaling, cell contacts, and mechanical forces within the gastrula. Together, these comprise a dynamic and complex regulatory cascade that drives gastrulation morphogenesis.
journal_name
Curr Opin Cell Bioljournal_title
Current opinion in cell biologyauthors
Williams ML,Solnica-Krezel Ldoi
10.1016/j.ceb.2017.04.006subject
Has Abstractpub_date
2017-10-01 00:00:00pages
33-39eissn
0955-0674issn
1879-0410pii
S0955-0674(16)30167-3journal_volume
48pub_type
杂志文章,评审abstract：:New structural analyses of the spectrin family of actin cross-linking proteins are providing molecular explanations for both the interchain binding between the alpha and beta chains of spectrin and the intermolecular associations between spectrin and other proteins. Additionally, the analyses bring into focus a confor...
journal_title：Current opinion in cell biology
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更新日期：1996-02-01 00:00:00
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journal_title：Current opinion in cell biology
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journal_title：Current opinion in cell biology
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.ceb.2009.12.008
更新日期：2010-04-01 00:00:00
abstract：:The control of translation and mRNA degradation plays a key role in the regulation of eukaryotic gene expression. In the cytosol, mRNAs engaged in translation are distributed throughout the cytosol, while translationally inactive mRNAs can accumulate in P bodies, in complex with mRNA degradation and translation repres...
journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.ceb.2008.06.002
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.ceb.2004.06.009
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in cell biology
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.ceb.2004.01.004
更新日期：2004-04-01 00:00:00
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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更新日期：1991-12-01 00:00:00
abstract：:The matrix metalloproteinases (MMPs) have been viewed as bulldozers, destroying the extracellular matrix to permit normal remodeling and contribute to pathological tissue destruction and tumor cell invasion. More recently, the identification of specific matrix and non-matrix substrates for MMPs and the elucidation of ...
journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/s0955-0674(00)00248-9
更新日期：2001-10-01 00:00:00
abstract：:In both prokaryotes and eukaryotes, transcription has been described as being temporally discontinuous, most genes being active mainly during short activity windows interspersed by silent periods. In mammalian cells, recent studies performed at the single cell level have revealed that transcriptional kinetics are high...
journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.ceb.2011.09.004
更新日期：2011-12-01 00:00:00
abstract：:The mitotic spindle assembly and chromosome segregation in eukaryotes must be coordinated with the nuclear envelope (NE) remodeling. In a so-called 'open' mitosis the envelope of the mother nucleus is dismantled allowing the cytoplasmic spindle microtubules to capture the chromosomes. Alternatively, cells undergoing '...
journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.ceb.2012.09.001
更新日期：2013-02-01 00:00:00
abstract：:This past year has seen a significant increase in our understanding of eukaryotic origins of replication, of the proteins that identify these origins, of DNA sequences that promote their unwinding, and of transcription factors that stimulate origin activity. DNA replication begins at specific sites in both simple and ...
journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/0955-0674(93)90008-e
更新日期：1993-06-01 00:00:00
abstract：:The adherens junction (AJ) is a major cell-cell junction that mediates cell recognition, adhesion, morphogenesis, and tissue integrity. Although AJs transmit forces generated by actomyosin from one cell to another, AJs have long been considered as an area where signal transduction from cadherin ligation takes place th...
journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/j.ceb.2011.07.001
更新日期：2011-10-01 00:00:00
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in cell biology
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journal_title：Current opinion in cell biology
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journal_title：Current opinion in cell biology
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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abstract：:Concomitant with packaging the genome, the cell nucleus must also spatially organize the nucleoplasm. This complex mixture of proteins and nucleic acids partitions into a variety of phase-separated, membraneless organelles called nuclear bodies. Significant progress has been made in understanding the relationship betw...
journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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更新日期：2017-06-01 00:00:00
abstract：:Actin filaments, microtubules, and intermediate filaments, have all been found to be dynamic structures in living cells. Recent studies have shed important light on the assembly, disassembly, and mobility of these structures. In addition, a growing emphasis has been placed on the regulation of cytoskeletal activities ...
journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
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abstract：:AB toxins deliver their enzymatically active A domain to the cytosol. Some AB-toxins are able to penetrate cellular membranes from endosomes where the low pH triggers their translocation. One such toxin is diphtheria toxin and important features of its translocation mechanism have been unraveled during the last year. ...
journal_title：Current opinion in cell biology
pub_type： 杂志文章,评审
doi：10.1016/s0955-0674(00)00109-5
更新日期：2000-08-01 00:00:00
