Abstract:
INTRODUCTION:Organizing pneumonia is a particular type of inflammatory reaction of the lung which gives rise to a clinico-pathological syndrome. It is called "secondary" when a cause such as an infection, a drug toxicity, or a connective tissue disease can be identified, or "cryptogenic" when no cause is identified. The clinical picture is usually characterized by the subacute onset of fever, fatigue, cough and dyspnea, with multiple subpleural areas of consolidation on thoracic imaging. STATE OF THE ART:Organizing pneumonia is characterised by the presence of buds of endoalveolar connective tissue. These result from an injury to the alveolar epithelium, followed by the deposition of fibrin in the alveolar spaces, and the migration of fibroblasts which produce a myxoid endoalveolar matrix. A remarkable feature of organizing pneumonia is the complete disappearance of these endoalveolar buds with corticosteroid treatment, in sharp contrast with what is seen in pulmonary fibrosis. The clinical response to corticosteroids is usually prompt and excellent. Relapses are frequent but usually benign. PERSPECTIVES AND CONCLUSION:As the clinical, imaging and pathological characteristics of organizing pneumonia are now well established, many questions remain unanswered, such as the mechanisms involved in the complete reversibility of the pulmonary lesions, and the role of steroid-sparing treatments such as immunomodulatory macrolides.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Petitpierre N,Beigelman C,Letovanec I,Lazor Rdoi
10.1016/j.rmr.2015.08.004subject
Has Abstractpub_date
2016-10-01 00:00:00pages
703-717issue
8eissn
0761-8425issn
1776-2588pii
S0761-8425(15)01110-9journal_volume
33pub_type
杂志文章,评审abstract::General reviews about occupational asthma divide the susceptible allergens capable of initiating asthma into two distinct groups: those of high and of low molecular weight. Atopy would be a risk factor for developing occupational asthma to high molecular weight allergens but not to those of low molecular weight. In th...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::Excessive widening of the alveolar-arterial gradient for oxygen, with respect to the subject's age and oxygen uptake, is the most sensitive signal of a disturbance in pulmonary gas exchange, whether it is due to ventilation, circulation or diffusion. During incremental exercise, simultaneous measurements of metabolic ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2012.05.018
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Thymic epithelial tumors (TET), including thymomas and thymic carcinomas, are rare and characterized by very different evolutionary patterns depending on histology and invasion stage. The therapeutic management is not well defined but is a subject of increasing interest. The descriptive and analytic objectiv...
journal_title:Revue des maladies respiratoires
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doi:10.1016/j.rmr.2013.09.015
更新日期:2014-09-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2010.07.005
更新日期:2010-10-01 00:00:00
abstract::Mediastinoscopy is a technique which enables palpation, inspection and biopsy of superior mediastinal glands. When this examination is done routinely in patients suffering from lung cancer which is presumed to be operable, 25-30% are found to have a positive gland and the greater part of these individuals become inope...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:2006-11-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2015.05.010
更新日期:2016-03-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2008-12-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2011.05.016
更新日期:2012-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(08)70465-0
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2009.08.004
更新日期:2010-02-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(09)72583-5
更新日期:2009-03-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1998-09-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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更新日期:2006-11-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2011-02-01 00:00:00
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journal_title:Revue des maladies respiratoires
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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更新日期:2016-09-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
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pub_type: 杂志文章
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