Abstract：
INTRODUCTION:There are few data on primary bronchial carcinoma in France. We report here the results of the study KBP 2000-CPHG in which there were 1868 patients aged 70 or more and 338 aged 80 or more. METHODS:We compared the patients under 70 (Group I) with those aged 70 or more (Group II) as well as with the details of the over 80's. RESULTS:Group II included significantly more women (17.4% vs 15.2%; p = 0.04), non-smokers (11.2% vs 5.3%; p<0.0001), patients of poor performance status (24.2% vs 14.5%; p<0.0001) and squamous carcinomas (44.5% vs 37.8%; p<0.001) than Group I, but fewer adenocarcinomas (27.2% vs 31.5%; p = 0.009) and as many small cell carcinomas (15.9% vs 16.9%; p = 0.32). In Group II there were less stage III and IV tumours (75.1% vs 78.1%; p = 0.0005) more symptomatic treatment (23.2% vs 6.1%) and radiotherapy alone (12.8% vs 3.8%; p < 0.0001). The results were similar beyond 80 years. On multivariate analysis age, performance status and stage appeared to be independent variables in the choice of curative or symptomatic treatment. CONCLUSIONS:Age alone is not therefore a limiting factor in the choice of treatment.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Piquet J,Blanchon F,Grivaux M,Collon T,Zureik M,Barbieux H,Bénichou-Flurin M,Breton JL,Coëtmeur D,Delclaux B,Braun D,Homasson JP,Mouysset F,Riou R,le Poulain-Doubliez M,Marsal L,CPHG.subject
Has Abstractpub_date
2004-11-01 00:00:00pages
8S70-8issue
5 Pt 3eissn
0761-8425issn
1776-2588journal_volume
21pub_type
杂志文章abstract：INTRODUCTION:The aim of the article is to present a summary of current knowledge on tobacco smoking in France available through representative population surveys. STATE OF ART:Smoking is very common in France as more than a quarter (28.7%) of 15-75years old individuals reported daily smoking in 2016. The rate is also ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2018.01.008
更新日期：2018-06-01 00:00:00
abstract：INTRODUCTION:Dry powder inhalers (DPIs) require a certain threshold of inspiratory effort to generate respirable particles. We undertook a literature review to determine whether this may, in particular clinical settings (young children, elderly subjects, acute or chronic respiratory obstructive syndromes - asthma and C...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/s0761-8425(05)85613-x
更新日期：2005-09-01 00:00:00
abstract：INTRODUCTION:Breath-hold diving has been practised since the dawn of humanity but is open to many risks. The consequences mainly involve the respiratory system. The pathophysiological mechanisms are complex because of the multiple forces applied to the body during breath-hold diving. OBSERVATION:The case reported here...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(07)74263-8
更新日期：2007-11-01 00:00:00
abstract：INTRODUCTION:Mycobacterium malmoense (MM) is an atypical mycobacterium responsible for opportunistic infection. The clinical and radiological picture is non-specific. The infection develops most frequently in a dystrophic lung. CASE REPORT:A patient of 52 years was admitted with an extensive multifocal pneumonia which...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(08)74984-2
更新日期：2008-11-01 00:00:00
abstract：INTRODUCTION:The correct use of medication and the ability to assess the severity of the disease and to react appropriately in the case of exacerbation are essential objectives in the management of asthma patients. This study, conducted in a school of asthma in Seine-Saint-Denis, aims to measure the influence of socio-...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2014.02.008
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:The high prevalence of allergic rhinitis that occurs in elite athletes has been extensively investigated. However, data among recreational athletes practicing indoor activities remain contradictory. The aim of the present study was to determine whether taking part in gym based sporting activities constitut...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2013.02.015
更新日期：2013-09-01 00:00:00
abstract：:Allergic bronchopulmonary aspergillosis (ABPA) is an immunologic bronchopulmonary inflammation due to an immune response of the lower respiratory tract against Aspergillus fumigatus. The major clinical features of ABPA include asthma, recurrent pulmonary infiltrates, immediate wheal and flare skin reactivity to A. fum...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：2000-02-01 00:00:00
abstract：:Epidermal growth factor receptor (EGFR) is a cell membrane tyrosine kinase receptor. Activating mutations at exon 19 and 21 of the EGFR gene are associated with the occurrence and development of lung adenocarcinoma. These gain of function mutations predict responsiveness to EGFR tyrosine kinase inhibitors (TKis), erlo...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2011.03.005
更新日期：2011-04-01 00:00:00
abstract：:Thrombocytopenia induced by rifampicin in the absence of prior sensitization is exceptional, especially when it occurs in a patient without risk factors. We report the case of a patient aged 25 years with no past history of medical, surgical or knowledge of having taken rifampicin previously, who was hospitalized for ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2013.03.009
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVES:To report the results of minimally invasive surgery in patients with stage I or II thymoma in the Masaoka classification. The reference technique is partial or complete thymectomy by sternotonomy. METHODS:A retrospective single-center study of a prospective database including all cases of thymoma operated f...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2017.01.002
更新日期：2017-05-01 00:00:00
abstract：:The aim of this study was to analyze the characteristics of patients on long-term continuous positive pressure therapy for obstructive sleep apnea in order to determine the efficacy, observance, tolerance, degree of patient satisfaction and patient quality of life using the Nottingham scale. A questionnaire was sent t...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:Since 1975, 340 patients were treated by tracheal sleeve resection for tracheal or subglottic laryngeal iatrogenic stenoses in our unit. Preoperative iterative Nd YAG laser sessions have usually been performed, without success. The length of the sleeve specimen was an average of 3 1/4 cm. Twelve patients died on the p...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：STATE OF THE ART:The IRAD2 trial is evaluating a 3-month home intervention which includes education, oral supplements, exercise and androgenic steroids in undernourished patients with chronic respiratory failure. The main objective is to increase the six-minute walking distance by more than 50 m with an improvement in ...
journal_title：Revue des maladies respiratoires
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0761-8425(04)71362-5
更新日期：2004-06-01 00:00:00
abstract：INTRODUCTION:Organizing pneumonia is a particular type of inflammatory reaction of the lung which gives rise to a clinico-pathological syndrome. It is called "secondary" when a cause such as an infection, a drug toxicity, or a connective tissue disease can be identified, or "cryptogenic" when no cause is identified. Th...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2015.08.004
更新日期：2016-10-01 00:00:00
abstract：:60 patients were studied with severe chronic respiratory failure (IRC) and a permanent tracheostomy treated with domiciliary ventilation (VADT). The study commenced from the time of the tracheostomy and included length of survival (by the actuarial method) quality of life, subjectively and objectively (progress of blo...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:Therapeutic options for patients with severe emphysema remain limited. In selected patients, lung volume reduction surgery has been shown to improve pulmonary function, exercise capacity, quality of life and also survival. The technique of inserting one-way valves endoscopically into the airways supplying th...
journal_title：Revue des maladies respiratoires
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0761-8425(04)71590-9
更新日期：2004-12-01 00:00:00
abstract：:Toxocariasis is a frequent disease in children, but the severe clinical manifestations are rare in the literature (diffuse interstitial pneumonia with hypoxaemia and acute severe asthma). The diagnosis is made thanks to the reliability of serological techniques (the ELISA test and using antigen excretion-secretion tes...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:The link between tuberculosis and HIV infection has long been established but the link between tuberculosis and smoking is not well understood. However, many patients with tuberculosis are smokers and an increasing proportion of them live in developing countries where there is a high incidence of the disease. Smoking ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2012.04.007
更新日期：2012-10-01 00:00:00
abstract：INTRODUCTION:Primary sarcomas of the mediastinum are rare and account for 2 to 8% of malignant mediastinal tumours. The aim of this study is to describe their clinical and pathological characteristics. PATIENTS AND METHODS:Fifteen cases of primary mediastinal sarcoma, diagnosed between 1993 and 2009, were reviewed ret...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/j.rmr.2010.05.015
更新日期：2011-01-01 00:00:00
abstract：INTRODUCTION:The nerve growth factor (NGF) is known as a factor involved in neuronal growth and survival. From recent studies it may also be considered as a mediator of inflammation, in particular in the airways. STATE OF ART:Several animal studies have shown that NGF may increase the sensory innervation, and particip...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/s0761-8425(04)71290-5
更新日期：2004-04-01 00:00:00
abstract：:Bradykinin and related kinins formed in tissues and fluids during inflammation, exert many physiological effects mediated by two receptor subtypes: B1 and B2. The involvement of kinins in bronchial asthma has been speculated in numerous clinicals reports. The effects of bradykinin on airways have been studied in vivo ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：:The feasibility and the good immediate acceptability of unilateral lung transplants in the patients with obstructive respiratory problems have recently been demonstrated and since the initial reports, some hundreds of lung transplants have been performed in various parts of the world for this indication. Nevertheless,...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:One out of two smokers who smoke throughout their lifetime will die from a disease related to smoking. Tobacco smoking therefore represents a major global public health issue. Smoking is the leading cause of chronic obstructive pulmonary disease (COPD). Projections for 2020 indicate that by then, COPD will have become...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2014.07.001
更新日期：2014-12-01 00:00:00
abstract：:Static lung hyperinflation is defined as the elevation of end- expiratory lung volume above its predicted value, with no increase in end-expiratory alveolar pressure, which remains equal to atmospheric pressure. Dynamic hyperinflation is the transient increase of this volume above the relaxation volume. In patients wi...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/s0761-8425(08)75094-0
更新日期：2008-12-01 00:00:00
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journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(07)91390-x
更新日期：2007-09-01 00:00:00
abstract：INTRODUCTION:Mechanical ventilation is associated with ventilator-induced diaphragmatic dysfunction (VIDD) in animal models and also in humans. BACKGROUND:The main pathophysiological pathways implicated in VIDD seems to be related to muscle inactivity but may also be the consequence of high tidal volumes. Systemic ins...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2014.08.013
更新日期：2015-04-01 00:00:00
abstract：METHODS:A questionnaire was sent to 50 000 general practicioners (GP) and specialists. RESULTS:4,898 physicians (9.4%) responded, including 59.1% GP, 16.9% pneumologists, 13% pediatricians and about 10% other specialists, ENT, allergologists, and intensivists. The main reason for pneumologists to prescribe nebulizatio...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：10.1016/s0761-8425(08)70465-0
更新日期：2008-01-01 00:00:00
abstract：:When administered in a single dose, nedocromil can inhibit the effect of various stimuli: adenosine, SO2, cold air, smog, tachykinins, metabisulfite, exercise and antigen. When administered in a chronic way, this preparation diminishes bronchial hyperresponsiveness. In a clinical study done in England, nedocromil has ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Excessive widening of the alveolar-arterial gradient for oxygen, with respect to the subject's age and oxygen uptake, is the most sensitive signal of a disturbance in pulmonary gas exchange, whether it is due to ventilation, circulation or diffusion. During incremental exercise, simultaneous measurements of metabolic ...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章,评审
doi：10.1016/j.rmr.2012.05.018
更新日期：2012-12-01 00:00:00
abstract：:Clinical data support the hypothesis that aggressivity is inhibited amongst asthmatics. The relationship of violence, as a marker of aggressiveness, to asthma was examined in a population-based sample of 12.466 students of secondary schools in France (Enquête sur la Santé de l'adolescent 1993/1994) using an epidemiolo...
journal_title：Revue des maladies respiratoires
pub_type： 杂志文章
doi：
更新日期：2001-06-01 00:00:00
