Abstract:
INTRODUCTION:Mycobacterium malmoense (MM) is an atypical mycobacterium responsible for opportunistic infection. The clinical and radiological picture is non-specific. The infection develops most frequently in a dystrophic lung. CASE REPORT:A patient of 52 years was admitted with an extensive multifocal pneumonia which later proved to be due to infection with MM. Empirical treatment was started with the combination of rifampicin, isoniazid, pyrazinamide (rifater) and ethambutol (myambutol). Subsequently, cultures showed sensitivity to rifampicin, ethambutol, oxfloxacin, clarithromycin (MIC < 2 mg/l) and rifabutin (MIC < 0.5 mg/l). More than two weeks after the start of treatment, material aspirated at fibroscopy showed the persistence of numerous acid-alcohol fast bacilli, an increase, compared with the original examination, from 5 to 25 per field on day 2, to 20 to 100 per field on day 19. Despite the late addition of clarithromycin there was a progressive deterioration in the pulmonary condition. CONCLUSION:There is little correlation between the in vivo and in vitro sensitivities of MM to antibiotics. In our patient the progress was unfavourable, even though the mycobacterium was sensitive to the combination of antibiotics used, with the exception of isoniazid that was not tested. In vitro isoniazid does not seem to be active against MM. There is no consensus of opinion on the antibiotic treatment of MM infections.
journal_name
Rev Mal Respirjournal_title
Revue des maladies respiratoiresauthors
Camara B,Borrel B,Panteix G,Merault JM,Vialas M,Sanchez A,Massip P,Barel Pdoi
10.1016/s0761-8425(08)74984-2subject
Has Abstractpub_date
2008-11-01 00:00:00pages
1127-30issue
9eissn
0761-8425issn
1776-2588pii
S0761-8425(08)74984-2journal_volume
25pub_type
杂志文章abstract:INTRODUCTION:Blunt chest trauma is a frequent injury and it can be difficult to evaluate its seriousness. The risk of acute decompensation because of an occult thoracic lesion is a significant and justified cause for concern. STATE OF ART:As is common in the case of trauma to the torso, few studies are available to gu...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2010.09.028
更新日期:2011-02-01 00:00:00
abstract:INTRODUCTION:Spinal metastases of lung cancer occur frequently and lead to the risk of spinal cord compression. Our objective is to clarify the management of this disease, emphasizing, in particular the use of prognostic scores. BACKGROUND:The first step is to evaluate the characteristics of the spinal lesion and its ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/j.rmr.2012.12.016
更新日期:2013-06-01 00:00:00
abstract::The authors review the literature about respiratory burns and their initial and late functional repercussions. Upper airway oedema induces initial upper airway obstructive impairment. Pulmonary parenchymal failure is characterised by the functional consequences observed with adult respiratory distress syndrome. Surviv...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
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更新日期:1985-01-01 00:00:00
abstract::Communication in oncology often means communicating in difficult circumstances. Moreover, "to tell" is an essential requirement in medicine. We need to make this communication a series of realistic proposals and proceed step by step. This is probably one of the greatest challenges that we have to face in oncology. The...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(08)74410-3
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journal_title:Revue des maladies respiratoires
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doi:10.1016/j.rmr.2009.11.006
更新日期:2010-01-01 00:00:00
abstract::The definition of asthma brings with it the idea of inflammation, as bronchial obstruction, which characterises it, is associated with bronchospasm, hypersecretion and oedema. In the asthmatic, awareness of the bronchial inflammation at the time of diagnosis is essential, as it contributes to prognosis and therapeutic...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1987-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2017.11.003
更新日期:2018-03-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:2005-12-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2008-10-01 00:00:00
abstract::In a prospective study the level of carcinoembryonic antigen (ACE) were simultaneously measured in plasma and bronchoalveolar lavage liquid (LBA), in fifteen patients suffering from bronchopulmonary cancer and fifteen patients suffering from non-malignant pulmonary disease. In these two groups the level of ACE in LBA ...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 临床试验,杂志文章
doi:10.1016/j.rmr.2011.01.008
更新日期:2011-05-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1996-11-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2013.09.013
更新日期:2014-05-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:10.1016/s0761-8425(04)71290-5
更新日期:2004-04-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2019.06.009
更新日期:2019-10-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2020-09-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/s0761-8425(04)71237-1
更新日期:2004-02-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2008-02-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1016/j.rmr.2010.05.019
更新日期:2011-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章
doi:10.1019/200530119
更新日期:2005-12-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
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更新日期:2016-10-01 00:00:00
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journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::Results of isolated surgical resection for stage III lung cancer are not satisfactory, since overall 5-year survival rates rarely exceed 15%. Deaths during follow-up are mainly due to metastatic progression. The multimodality approach adds chemotherapy to surgery, with the intent to improve the control of micrometasta...
journal_title:Revue des maladies respiratoires
pub_type: 杂志文章,评审
doi:
更新日期:1998-06-01 00:00:00