A novel EBNA-1 titration method and putative anti-EBNA-1 protein.

Abstract:

:A novel and rapid EBNA-1 titration method has been developed which uses immunoprecipitation of specific DNA-protein complexes with EBNA-1-positive serum. The method is more sensitive than the conventional immunofluorescence method and has potential value as a diagnostic reagent for clinical laboratories. TPA induction of putative anti-EBNA-1 protein of cellular origin is discussed, which may play a key role for the shift from latent to lytic replication of EBV.

journal_name

J Virol Methods

authors

Nonoyama M,Wen LT,Tabata T,Tanaka A

doi

10.1016/0166-0934(88)90062-6

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

161-70

issue

1-4

eissn

0166-0934

issn

1879-0984

pii

0166-0934(88)90062-6

journal_volume

21

pub_type

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