The logic of equivalence testing and its use in laboratory medicine.

abstract：:An increasing prevalence of gestational diabetes has become a very challenging task in prenatal care worldwide. International Association of Diabetes and Pregnancy Study Groups (IADPSG) has recently issued recommendations on the diagnosis and classification of hyperglycaemia in pregnancy. These recommendations, the fi...

journal_title：Biochemia medica

authors： Lovrencić MV,Honović L,Kralik S,Matica J,Prasek M,Pape-Medvidović E,Ivanisević M,Delmis J

更新日期：2013-01-01 00:00:00

abstract：Introduction:Liquid chromatography coupled to atmospheric pressure ionization tandem mass spectrometry (LC-ESI-MS/MS) is currently considered the reference method for quantitative determination of urinary free cortisol (UFC). One of the major drawbacks of this measurement is a particular form of matrix effect, conventi...

journal_title：Biochemia medica

authors： Danese E,Salvagno GL,Guzzo A,Scurati S,Fava C,Lippi G

更新日期：2017-10-15 00:00:00

abstract：:Preanalytical phase is the most vulnerable part of the total testing process and is considered to be among the greatest challenges to the laboratory professionals. However, preanalytical activities, management of unsuitable specimens and reporting policies are not fully standardized, nor harmonized worldwide. Several ...

journal_title：Biochemia medica

authors： Simundic AM,Lippi G

更新日期：2012-01-01 00:00:00

abstract：:Diagnostic tests are important clinical tools. Bayes' theorem and Bayesian approach are important methods for interpreting test results. The Bayesian factor, the so-called likelihood ratio, has not always been well-understood. In this article, we try to discuss the likelihood ratio and its value for a specific test re...

journal_title：Biochemia medica

authors： Habibzadeh F,Habibzadeh P

更新日期：2019-06-15 00:00:00

abstract：Introduction:Severe hyperkalaemia is a serious medical condition requiring immediate medical attention. Before medical treatment is started, pseudohyperkalaemia has to be ruled out. Case description:A 10-month old infant presented to the emergency department with fever and coughing since 1 week. Routine venous blood t...

journal_title：Biochemia medica

authors： Van Elslande J,Dominicus T,Toelen J,Frans G,Vermeersch P

更新日期：2020-06-15 00:00:00

abstract：Introduction:In recent years, Six Sigma metrics has became the hotspot in all trades and professions, which contributes a general procedure to explain the performance on sigma scale. Nowadays, many large companies, such as General Healthcare, Siemens, etc., have applied Six Sigma to clinical medicine and achieved satis...

journal_title：Biochemia medica

authors： Mao X,Shao J,Zhang B,Wang Y

更新日期：2018-06-15 00:00:00

abstract：INTRODUCTION:Although prostatitis is a common male urinary tract infection, clinical diagnosis of prostatitis is difficult. The developmental mechanism of prostatitis is not yet unraveled which led to the elaboration of various biomarkers. As changes in asparagine-linked-(N-)-glycosylation were observed between healthy...

journal_title：Biochemia medica

authors： Vermassen T,Van Praet C,Poelaert F,Lumen N,Decaestecker K,Hoebeke P,Van Belle S,Rottey S,Delanghe J

更新日期：2015-10-15 00:00:00

abstract：Introduction:Measurement of parathyroid hormone (PTH) is essential in the investigation and management of calcium metabolism disorders. To assess the significance of any assay result when clinical decision making biological variation (BV) of the measurand must be taken into consideration. The aim of the present study i...

journal_title：Biochemia medica

authors： Ercan M,Akbulut ED,Avcı E,Yücel Ç,Oğuz EF,Turhan T,Serdar M

更新日期：2019-10-15 00:00:00

abstract：:Accumulating evidence shows that chronic inflammation is associated to increased risk of cancer. An inflammatory component is present also in the microenvironment of tumours epidemiologically unrelated to inflammation. Extensive investigations over the past decade have uncovered many of the important mechanistic pathw...

journal_title：Biochemia medica

authors： Del Prete A,Allavena P,Santoro G,Fumarulo R,Corsi MM,Mantovani A

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:The usefulness and cost-effectiveness of routine laboratory preoperative tests (POTs) have been challenged recently. In fact, the American Society of Anesthesiologists (ASA) Task Force has stated that test results obtained from the medical record within 6 months of surgery generally are mostly acceptable. ...

journal_title：Biochemia medica

authors： Rodríguez-Borja E,Corchon-Peyrallo A,Aguilar-Aguilar G,Carratala-Calvo A

更新日期：2017-10-15 00:00:00

abstract：INTRODUCTION:Our aim was to investigate if: (a) authors of Biochemia Medica meet authorship criteria given by International Committee of Medical Journal Editors (ICMJE), (b) authorship violations are more frequent in submissions containing some type of scientific misconduct. MATERIALS AND METHODS:Self-reported authors...

journal_title：Biochemia medica

authors： Šupak-Smolčić V,Mlinarić A,Antončić D,Horvat M,Omazić J,Šimundić AM

更新日期：2015-10-15 00:00:00

abstract：Introduction:Reference intervals (RIs) for complement assays in EDTA plasma samples have not previously been published. The objectives of the present study were to validate and/or determine RIs for classical pathway (CP50) activity and C3c, C4 and C1 inhibitor protein (C1INH) assays and to assess the need for age-speci...

journal_title：Biochemia medica

authors： Lopez B,Bertier N,Ledoult E,Joudinaud R,Maanaoui M,Majerus V,Moitrot E,Deleplancque AS,Rogeau S,Launay D,Lefèvre G,Labalette M,Dubucquoi S

更新日期：2019-10-15 00:00:00

abstract：:Authorship problems are deep-rooted in the field of science communication. Some of these relate to lack of specific journal instructions. For decades, experts in journal editing and publishing have been exploring the authorship criteria and contributions deserving either co-authorship or acknowledgment. The issue of i...

journal_title：Biochemia medica

authors： Gasparyan AY,Yessirkepov M,Gerasimov AN,Kostyukova EI,Kitas GD

更新日期：2016-01-01 00:00:00

abstract：Introduction:Autovalidation (AV) is an algorithm based on predefined rules designed, among others, to automate and standardize the postanalytical phase of laboratory work. The aim of this study was to examine the overall opinion of Croatian medical biochemistry laboratories regarding various aspects of AV. Material an...

journal_title：Biochemia medica

authors： Rimac V,Jokic A,Podolar S,Vlasic Tanaskovic J,Honovic L,Lenicek Krleza J

更新日期：2020-06-15 00:00:00

abstract：:Urinary angiotensin converting enzyme 2 (ACE2) is significantly increased in diabetes and diabetic nephropathy. While studies on its clinical significance are still underway, its urinary expression, association with metabolic and renal parameters has been in the recent past considerably studied. The recent studies hav...

journal_title：Biochemia medica

authors： Gilbert A,Liu J,Cheng G,An C,Deo K,Gorret AM,Qin X

更新日期：2019-02-15 00:00:00

abstract：:Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus (DM) and a leading cause of blindness in working-age adults in developed countries. Numerous investigations have recognised inflammation and angiogenesis as important factors in the development of this complication of ...

journal_title：Biochemia medica

authors： Kaštelan S,Orešković I,Bišćan F,Kaštelan H,Gverović Antunica A

更新日期：2020-10-15 00:00:00

abstract：:In this paper we would like to briefly introduce readers to the situation in the field of laboratory medicine in Bosnia and Herzegovina, with a focus on training in the field of medical biochemistry. As in some of neighboring countries, term Medical biochemist is the usual name for the Clinical biochemist or Clinical ...

journal_title：Biochemia medica

authors： Winterhalter-Jadrić M,Causević A,Jadrić R,Corić J,Hasić S,Kiseljaković E

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:The aim of this work is twofold. Firstly, to study the temporal evolution in the number of laboratory requests from primary care without clinical indication, and to analyse the number of such requests before and after the implementation of an automated requesting procedure. Secondly, to investigate what ar...

journal_title：Biochemia medica

authors： Salinas M,López-Garrigós M,Flores E,Leiva-Salinas M,Esteban P,Ahumada M,Leiva-Salinas C

更新日期：2016-10-15 00:00:00

abstract：INTRODUCTION:Acute kidney injury (AKI) is common in neonatal intensive care units (NICU). In recent years, every effort is made for early detection of AKI. Our hypothesis was that serum neutrophil gelatinase-associated lipocalin (sNGAL) may be a reliable screening test for early diagnosis of AKI in premature neonates a...

journal_title：Biochemia medica

authors： Pejović B,Erić-Marinković J,Pejović M,Kotur-Stevuljević J,Peco-Antić A

更新日期：2015-10-15 00:00:00

abstract：:Eosinophil cationic protein (ECP) is a heterogeneous molecule originating from activated eosinophil granulocytes. Biological activity and the cellular content of ECP are determined by genetic and posttranslational factors. Several single nucleotide polymorphisms (SNPs) in human ECP gene (RNASE3) have been described so...

journal_title：Biochemia medica

authors： Topic RZ,Dodig S

更新日期：2011-01-01 00:00:00

abstract：Introduction:Macroprolactinaemia is a well-known analytical problem in diagnostics of hyperprolactinaemia usually detected with polyethylene glycol (PEG) precipitation method. Since there is no harmonization in macroprolactin detection and reporting results, this study proposes and evaluates the usefulness of in-house ...

journal_title：Biochemia medica

authors： Šostarić M,Bokulić A,Marijančević D,Zec I

更新日期：2019-06-15 00:00:00

abstract：INTRODUCTION:The opening of research data is emerging thanks to the increasing possibilities of digital technology. The opening of clinical trial (CT) data is a part of this process, expected to have positive scientific, ethical, health, and economic impacts thus contributing to research integrity. The January 2016 pro...

journal_title：Biochemia medica

authors： Krleža-Jerić K,Gabelica M,Banzi R,Martinić MK,Pulido B,Mahmić-Kaknjo M,Reveiz L,Šimić J,Utrobičić A,Hrgović I

更新日期：2016-10-15 00:00:00

abstract：:Reliable procedures are needed to quantify the performance of instruments and methods in order to increase the quality in clinical laboratories. The Sigma metrics serves that purpose, and in the present study, the current methods for the calculation of the Sigma metrics are critically evaluated. Although the conventio...

journal_title：Biochemia medica

authors： Oosterhuis WP,Coskun A

更新日期：2018-06-15 00:00:00

abstract：:The Chi-square statistic is a non-parametric (distribution free) tool designed to analyze group differences when the dependent variable is measured at a nominal level. Like all non-parametric statistics, the Chi-square is robust with respect to the distribution of the data. Specifically, it does not require equality o...

journal_title：Biochemia medica

authors： McHugh ML

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:We examined the cost-effectiveness of the three different D-dimer measurements in the screening of DVT in models with and without calculation of pre-test probability (PTP) score. Moreover, we calculated the minimal cost in DVT detection. MATERIAL AND METHODS:In the group of 192 patients with clinically su...

journal_title：Biochemia medica

authors： Bogavac-Stanojević N,Dopsaj V,Jelić-Ivanović Z,Lakić D,Vasić D,Petrova G

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Winter swimming represents an intensive short-term exposure to cold, and thus it is considered a strong physical stress. Cold-based treatments, i.e. immersions in cold water, are spreading in sport medicine for improving recovery following muscle traumas, although a universal acceptance of that method is n...

journal_title：Biochemia medica

authors： Lombardi G,Ricci C,Banfi G

更新日期：2011-01-01 00:00:00

abstract：:With considering serum concentration of the uric acid in humans we are observing hyperuricemia and possible gout development. Many epidemiological studies have shown the relationship between the uric acid and different disorders such are obesity, metabolic syndrome, hypertension and coronary artery disease. Clinicians...

journal_title：Biochemia medica

authors： Pasalic D,Marinkovic N,Feher-Turkovic L

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Glycolysis affects glucose determination in vitro. The placement of sample tubes in ice-water slurry with plasma separation within 30 minutes is recommended, or alternatively the use of a glycolysis inhibitor. The aim of our two-steps study was to evaluate which Terumo tube is best for glucose determinatio...

journal_title：Biochemia medica

authors： Bonetti G,Carta M,Montagnana M,Lo Cascio C,Bonfigli AR,Mosca A,Testa R,Italian joint SIBioC-SIPMeL Study Group on Diabetes Mellitus.

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study is to present a case of 44 years old woman with topiramate induced metabolic acidosis and kidney stones. MATERIALS AND METHODS:The laboratory features of topiramate caused renal tubular acidosis in blood and urine during topiramate treatment, with correction of metabolic acidosis by ...

journal_title：Biochemia medica

authors： Salek T,Andel I,Kurfurstova I

更新日期：2017-06-15 00:00:00

abstract：:Peer review is widely used system for evaluating manuscripts prior to publication. It has been and still is widely used tool for making justified and fair editorial decision. However, the evidence of its efficacy is limited and it has been criticized to be time-consuming, biased, inconsistent, conservative, and open t...

journal_title：Biochemia medica

authors： Smolčić VŠ,Simundić AM

更新日期：2014-10-15 00:00:00