Economic evaluation of different screening alternatives for patients with clinically suspected acute deep vein thrombosis.

abstract：Introduction:Macroprolactinaemia is a well-known analytical problem in diagnostics of hyperprolactinaemia usually detected with polyethylene glycol (PEG) precipitation method. Since there is no harmonization in macroprolactin detection and reporting results, this study proposes and evaluates the usefulness of in-house ...

journal_title：Biochemia medica

authors： Šostarić M,Bokulić A,Marijančević D,Zec I

更新日期：2019-06-15 00:00:00

abstract：Introduction:It is often quoted that 70% of clinical decisions are based on laboratory results, but the evidence to substantiate this claim is lacking. Since clinical guidelines aim to document best-practice decision making for specific disease conditions, inclusion of any laboratory test means that the best available ...

journal_title：Biochemia medica

authors： Hicks AJ,Carwardine ZL,Hallworth MJ,Kilpatrick ES

更新日期：2021-02-15 00:00:00

abstract：:The Chi-square statistic is a non-parametric (distribution free) tool designed to analyze group differences when the dependent variable is measured at a nominal level. Like all non-parametric statistics, the Chi-square is robust with respect to the distribution of the data. Specifically, it does not require equality o...

journal_title：Biochemia medica

authors： McHugh ML

更新日期：2013-01-01 00:00:00

abstract：Introduction:Measurement of parathyroid hormone (PTH) is essential in the investigation and management of calcium metabolism disorders. To assess the significance of any assay result when clinical decision making biological variation (BV) of the measurand must be taken into consideration. The aim of the present study i...

journal_title：Biochemia medica

authors： Ercan M,Akbulut ED,Avcı E,Yücel Ç,Oğuz EF,Turhan T,Serdar M

更新日期：2019-10-15 00:00:00

abstract：Introduction:Liquid chromatography coupled to atmospheric pressure ionization tandem mass spectrometry (LC-ESI-MS/MS) is currently considered the reference method for quantitative determination of urinary free cortisol (UFC). One of the major drawbacks of this measurement is a particular form of matrix effect, conventi...

journal_title：Biochemia medica

authors： Danese E,Salvagno GL,Guzzo A,Scurati S,Fava C,Lippi G

更新日期：2017-10-15 00:00:00

abstract：INTRODUCTION:Winter swimming represents an intensive short-term exposure to cold, and thus it is considered a strong physical stress. Cold-based treatments, i.e. immersions in cold water, are spreading in sport medicine for improving recovery following muscle traumas, although a universal acceptance of that method is n...

journal_title：Biochemia medica

authors： Lombardi G,Ricci C,Banfi G

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:The usefulness and cost-effectiveness of routine laboratory preoperative tests (POTs) have been challenged recently. In fact, the American Society of Anesthesiologists (ASA) Task Force has stated that test results obtained from the medical record within 6 months of surgery generally are mostly acceptable. ...

journal_title：Biochemia medica

authors： Rodríguez-Borja E,Corchon-Peyrallo A,Aguilar-Aguilar G,Carratala-Calvo A

更新日期：2017-10-15 00:00:00

abstract：:Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus (DM) and a leading cause of blindness in working-age adults in developed countries. Numerous investigations have recognised inflammation and angiogenesis as important factors in the development of this complication of ...

journal_title：Biochemia medica

authors： Kaštelan S,Orešković I,Bišćan F,Kaštelan H,Gverović Antunica A

更新日期：2020-10-15 00:00:00

abstract：INTRODUCTION:The opening of research data is emerging thanks to the increasing possibilities of digital technology. The opening of clinical trial (CT) data is a part of this process, expected to have positive scientific, ethical, health, and economic impacts thus contributing to research integrity. The January 2016 pro...

journal_title：Biochemia medica

authors： Krleža-Jerić K,Gabelica M,Banzi R,Martinić MK,Pulido B,Mahmić-Kaknjo M,Reveiz L,Šimić J,Utrobičić A,Hrgović I

更新日期：2016-10-15 00:00:00

abstract：:Authorship problems are deep-rooted in the field of science communication. Some of these relate to lack of specific journal instructions. For decades, experts in journal editing and publishing have been exploring the authorship criteria and contributions deserving either co-authorship or acknowledgment. The issue of i...

journal_title：Biochemia medica

authors： Gasparyan AY,Yessirkepov M,Gerasimov AN,Kostyukova EI,Kitas GD

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study is to present a case of 44 years old woman with topiramate induced metabolic acidosis and kidney stones. MATERIALS AND METHODS:The laboratory features of topiramate caused renal tubular acidosis in blood and urine during topiramate treatment, with correction of metabolic acidosis by ...

journal_title：Biochemia medica

authors： Salek T,Andel I,Kurfurstova I

更新日期：2017-06-15 00:00:00

abstract：INTRODUCTION:The aim of this work is twofold. Firstly, to study the temporal evolution in the number of laboratory requests from primary care without clinical indication, and to analyse the number of such requests before and after the implementation of an automated requesting procedure. Secondly, to investigate what ar...

journal_title：Biochemia medica

authors： Salinas M,López-Garrigós M,Flores E,Leiva-Salinas M,Esteban P,Ahumada M,Leiva-Salinas C

更新日期：2016-10-15 00:00:00

abstract：:Logistic regression is used to obtain odds ratio in the presence of more than one explanatory variable. The procedure is quite similar to multiple linear regression, with the exception that the response variable is binomial. The result is the impact of each variable on the odds ratio of the observed event of interest....

journal_title：Biochemia medica

authors： Sperandei S

更新日期：2014-02-15 00:00:00

abstract：:Peer review is widely used system for evaluating manuscripts prior to publication. It has been and still is widely used tool for making justified and fair editorial decision. However, the evidence of its efficacy is limited and it has been criticized to be time-consuming, biased, inconsistent, conservative, and open t...

journal_title：Biochemia medica

authors： Smolčić VŠ,Simundić AM

更新日期：2014-10-15 00:00:00

abstract：:Extravascular body fluids (EBF) analysis can provide useful information in the differential diagnosis of conditions that caused their accumulation. Their unique nature and particular requirements accompanying EBF analysis need to be recognized in order to minimize possible negative implications on patient safety. This...

journal_title：Biochemia medica

authors： Milevoj Kopcinovic L,Culej J,Jokic A,Bozovic M,Kocijan I

更新日期：2020-02-15 00:00:00

abstract：Introduction:Reference intervals (RIs) for complement assays in EDTA plasma samples have not previously been published. The objectives of the present study were to validate and/or determine RIs for classical pathway (CP50) activity and C3c, C4 and C1 inhibitor protein (C1INH) assays and to assess the need for age-speci...

journal_title：Biochemia medica

authors： Lopez B,Bertier N,Ledoult E,Joudinaud R,Maanaoui M,Majerus V,Moitrot E,Deleplancque AS,Rogeau S,Launay D,Lefèvre G,Labalette M,Dubucquoi S

更新日期：2019-10-15 00:00:00

abstract：INTRODUCTION:Duplicate measurements can be used to describe the performance and analytical robustness of assays and to identify outliers. We performed about 235,000 duplicate measurements of nine routinely measured quantities and evaluated the observed differences between the replicates to develop new markers for analy...

journal_title：Biochemia medica

authors： Neubig S,Grotevendt A,Kallner A,Nauck M,Petersmann A

更新日期：2017-02-15 00:00:00

abstract：:This systematic review presents the latest trends in salivary research and its applications in health and disease. Among the large number of analytes present in saliva, many are affected by diverse physiological and pathological conditions. Further, the non-invasive, easy and cost-effective collection methods prompt a...

journal_title：Biochemia medica

authors： Nunes LA,Mussavira S,Bindhu OS

更新日期：2015-06-05 00:00:00

abstract：INTRODUCTION:Although prostatitis is a common male urinary tract infection, clinical diagnosis of prostatitis is difficult. The developmental mechanism of prostatitis is not yet unraveled which led to the elaboration of various biomarkers. As changes in asparagine-linked-(N-)-glycosylation were observed between healthy...

journal_title：Biochemia medica

authors： Vermassen T,Van Praet C,Poelaert F,Lumen N,Decaestecker K,Hoebeke P,Van Belle S,Rottey S,Delanghe J

更新日期：2015-10-15 00:00:00

abstract：INTRODUCTION:Acute kidney injury (AKI) is common in neonatal intensive care units (NICU). In recent years, every effort is made for early detection of AKI. Our hypothesis was that serum neutrophil gelatinase-associated lipocalin (sNGAL) may be a reliable screening test for early diagnosis of AKI in premature neonates a...

journal_title：Biochemia medica

authors： Pejović B,Erić-Marinković J,Pejović M,Kotur-Stevuljević J,Peco-Antić A

更新日期：2015-10-15 00:00:00

abstract：:A 51-year old male patient was admitted to the hospital with acute dyspnea and history of chronic asthma. Venous blood was drawn into a 3.0 mL heparinized syringe and delivered to the laboratory for blood gas analysis (GEM Premier 4000, Instrumentation Laboratory), which revealed high potassium value (5.2 mmol/L; refe...

journal_title：Biochemia medica

authors： Salvagno GL,Demonte D,Lippi G

更新日期：2019-02-15 00:00:00

abstract：:In Croatian medical laboratories (ML), external quality assessment (EQA) has a long tradition of almost half of a century. At national level, EQA is provided by Croatian Centre for Quality Assessment in Laboratory Medicine (CROQALM) which is a part of Croatian Society of Medical Biochemistry and Laboratory Medicine.
T...

journal_title：Biochemia medica

authors： Krleza JL,Celap I,Tanaskovic JV

更新日期：2017-02-15 00:00:00

abstract：INTRODUCTION:The phlebotomists' procedures are a still source of laboratory variability. The aim of this study was to verify the efficacy of minor modification in procedure for collection of diagnostic blood specimens by venipuncture from CLSI H03-A6 document is able to reduce the tourniquet application time. MATERIAL...

journal_title：Biochemia medica

authors： Lima-Oliveira G,Lippi G,Salvagno GL,Montagnana M,Picheth G,Guidi GC

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Glycolysis affects glucose determination in vitro. The placement of sample tubes in ice-water slurry with plasma separation within 30 minutes is recommended, or alternatively the use of a glycolysis inhibitor. The aim of our two-steps study was to evaluate which Terumo tube is best for glucose determinatio...

journal_title：Biochemia medica

authors： Bonetti G,Carta M,Montagnana M,Lo Cascio C,Bonfigli AR,Mosca A,Testa R,Italian joint SIBioC-SIPMeL Study Group on Diabetes Mellitus.

更新日期：2016-01-01 00:00:00

abstract：:The kappa statistic is frequently used to test interrater reliability. The importance of rater reliability lies in the fact that it represents the extent to which the data collected in the study are correct representations of the variables measured. Measurement of the extent to which data collectors (raters) assign th...

journal_title：Biochemia medica

authors： McHugh ML

更新日期：2012-01-01 00:00:00

abstract：Introduction:The measurement of β-hydroxybutyrate (βOHB) concentrations is a corner stone of the diagnosis of diabetic ketoacidosis and other ketonic states. The aim of this study was to perform a validation of a peripheral blood βOHB assay (Randox) on a Roche cobas c502 analyser and to establish a βOHB reference range...

journal_title：Biochemia medica

authors： Kraus FB,Kocijancic M,Kluttig A,Ludwig-Kraus B

更新日期：2020-02-15 00:00:00

abstract：:In this paper we would like to briefly introduce readers to the situation in the field of laboratory medicine in Bosnia and Herzegovina, with a focus on training in the field of medical biochemistry. As in some of neighboring countries, term Medical biochemist is the usual name for the Clinical biochemist or Clinical ...

journal_title：Biochemia medica

authors： Winterhalter-Jadrić M,Causević A,Jadrić R,Corić J,Hasić S,Kiseljaković E

更新日期：2011-01-01 00:00:00

abstract：:Reliable procedures are needed to quantify the performance of instruments and methods in order to increase the quality in clinical laboratories. The Sigma metrics serves that purpose, and in the present study, the current methods for the calculation of the Sigma metrics are critically evaluated. Although the conventio...

journal_title：Biochemia medica

authors： Oosterhuis WP,Coskun A

更新日期：2018-06-15 00:00:00

abstract：INTRODUCTION:Many additional tasks in the Stat laboratory (SL) increase the workload. It is necessary to control them because they can affect the service provided by the laboratory. Our aim is to calculate these tasks, study their evolution over a 10 year period, and compare turnaround times (TAT) in summer period to t...

journal_title：Biochemia medica

authors： Salinas M,López-Garrigós M,Flores E,Leiva-Salinas M,Lillo R,Leiva-Salinas C

更新日期：2016-01-01 00:00:00

abstract：:Accumulating evidence shows that chronic inflammation is associated to increased risk of cancer. An inflammatory component is present also in the microenvironment of tumours epidemiologically unrelated to inflammation. Extensive investigations over the past decade have uncovered many of the important mechanistic pathw...

journal_title：Biochemia medica

authors： Del Prete A,Allavena P,Santoro G,Fumarulo R,Corsi MM,Mantovani A

更新日期：2011-01-01 00:00:00