Using clinical guidelines to assess the potential value of laboratory medicine in clinical decision-making.

abstract：:A 51-year old male patient was admitted to the hospital with acute dyspnea and history of chronic asthma. Venous blood was drawn into a 3.0 mL heparinized syringe and delivered to the laboratory for blood gas analysis (GEM Premier 4000, Instrumentation Laboratory), which revealed high potassium value (5.2 mmol/L; refe...

journal_title：Biochemia medica

authors： Salvagno GL,Demonte D,Lippi G

更新日期：2019-02-15 00:00:00

abstract：INTRODUCTION:The phlebotomists' procedures are a still source of laboratory variability. The aim of this study was to verify the efficacy of minor modification in procedure for collection of diagnostic blood specimens by venipuncture from CLSI H03-A6 document is able to reduce the tourniquet application time. MATERIAL...

journal_title：Biochemia medica

authors： Lima-Oliveira G,Lippi G,Salvagno GL,Montagnana M,Picheth G,Guidi GC

更新日期：2013-01-01 00:00:00

abstract：:The Chi-square statistic is a non-parametric (distribution free) tool designed to analyze group differences when the dependent variable is measured at a nominal level. Like all non-parametric statistics, the Chi-square is robust with respect to the distribution of the data. Specifically, it does not require equality o...

journal_title：Biochemia medica

authors： McHugh ML

更新日期：2013-01-01 00:00:00

abstract：Introduction:Liquid chromatography coupled to atmospheric pressure ionization tandem mass spectrometry (LC-ESI-MS/MS) is currently considered the reference method for quantitative determination of urinary free cortisol (UFC). One of the major drawbacks of this measurement is a particular form of matrix effect, conventi...

journal_title：Biochemia medica

authors： Danese E,Salvagno GL,Guzzo A,Scurati S,Fava C,Lippi G

更新日期：2017-10-15 00:00:00

abstract：INTRODUCTION:ISO 15189 was a new standard published in 2003 for accrediting medical laboratories. We believe that some requirements of the ISO 15189 standard are especially difficult to meet for majority of laboratories. The aim of this article was to present the frequency of nonconformities to requirements of the ISO ...

journal_title：Biochemia medica

authors： Ho B,Ho E

更新日期：2012-01-01 00:00:00

abstract：Introduction:Reference intervals (RIs) for complement assays in EDTA plasma samples have not previously been published. The objectives of the present study were to validate and/or determine RIs for classical pathway (CP50) activity and C3c, C4 and C1 inhibitor protein (C1INH) assays and to assess the need for age-speci...

journal_title：Biochemia medica

authors： Lopez B,Bertier N,Ledoult E,Joudinaud R,Maanaoui M,Majerus V,Moitrot E,Deleplancque AS,Rogeau S,Launay D,Lefèvre G,Labalette M,Dubucquoi S

更新日期：2019-10-15 00:00:00

abstract：Introduction:Severe hyperkalaemia is a serious medical condition requiring immediate medical attention. Before medical treatment is started, pseudohyperkalaemia has to be ruled out. Case description:A 10-month old infant presented to the emergency department with fever and coughing since 1 week. Routine venous blood t...

journal_title：Biochemia medica

authors： Van Elslande J,Dominicus T,Toelen J,Frans G,Vermeersch P

更新日期：2020-06-15 00:00:00

abstract：:Diagnostic tests are important clinical tools. Bayes' theorem and Bayesian approach are important methods for interpreting test results. The Bayesian factor, the so-called likelihood ratio, has not always been well-understood. In this article, we try to discuss the likelihood ratio and its value for a specific test re...

journal_title：Biochemia medica

authors： Habibzadeh F,Habibzadeh P

更新日期：2019-06-15 00:00:00

abstract：:Reliable procedures are needed to quantify the performance of instruments and methods in order to increase the quality in clinical laboratories. The Sigma metrics serves that purpose, and in the present study, the current methods for the calculation of the Sigma metrics are critically evaluated. Although the conventio...

journal_title：Biochemia medica

authors： Oosterhuis WP,Coskun A

更新日期：2018-06-15 00:00:00

abstract：:Authorship problems are deep-rooted in the field of science communication. Some of these relate to lack of specific journal instructions. For decades, experts in journal editing and publishing have been exploring the authorship criteria and contributions deserving either co-authorship or acknowledgment. The issue of i...

journal_title：Biochemia medica

authors： Gasparyan AY,Yessirkepov M,Gerasimov AN,Kostyukova EI,Kitas GD

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Winter swimming represents an intensive short-term exposure to cold, and thus it is considered a strong physical stress. Cold-based treatments, i.e. immersions in cold water, are spreading in sport medicine for improving recovery following muscle traumas, although a universal acceptance of that method is n...

journal_title：Biochemia medica

authors： Lombardi G,Ricci C,Banfi G

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Urinary tract infection (UTI) is one of the most common bacterial infectious diseases in children. The aim of this study was to determine the total prooxidant and antioxidant capacity of children with UTI, as well as changes of oxidative status parameters according to acute inflammation persistence and acu...

journal_title：Biochemia medica

authors： Petrovic S,Bogavac-Stanojevic N,Kotur-Stevuljevic J,Peco-Antic A,Ivanisevic I,Ivanisevic J,Paripovic D,Jelic-Ivanovic Z

更新日期：2014-01-01 00:00:00

abstract：:Preanalytical phase is the most vulnerable part of the total testing process and is considered to be among the greatest challenges to the laboratory professionals. However, preanalytical activities, management of unsuitable specimens and reporting policies are not fully standardized, nor harmonized worldwide. Several ...

journal_title：Biochemia medica

authors： Simundic AM,Lippi G

更新日期：2012-01-01 00:00:00

abstract：:In Croatian medical laboratories (ML), external quality assessment (EQA) has a long tradition of almost half of a century. At national level, EQA is provided by Croatian Centre for Quality Assessment in Laboratory Medicine (CROQALM) which is a part of Croatian Society of Medical Biochemistry and Laboratory Medicine.
T...

journal_title：Biochemia medica

authors： Krleza JL,Celap I,Tanaskovic JV

更新日期：2017-02-15 00:00:00

abstract：Introduction:Autovalidation (AV) is an algorithm based on predefined rules designed, among others, to automate and standardize the postanalytical phase of laboratory work. The aim of this study was to examine the overall opinion of Croatian medical biochemistry laboratories regarding various aspects of AV. Material an...

journal_title：Biochemia medica

authors： Rimac V,Jokic A,Podolar S,Vlasic Tanaskovic J,Honovic L,Lenicek Krleza J

更新日期：2020-06-15 00:00:00

abstract：INTRODUCTION:Our aim was to investigate if: (a) authors of Biochemia Medica meet authorship criteria given by International Committee of Medical Journal Editors (ICMJE), (b) authorship violations are more frequent in submissions containing some type of scientific misconduct. MATERIALS AND METHODS:Self-reported authors...

journal_title：Biochemia medica

authors： Šupak-Smolčić V,Mlinarić A,Antončić D,Horvat M,Omazić J,Šimundić AM

更新日期：2015-10-15 00:00:00

abstract：:Eosinophil cationic protein (ECP) is a heterogeneous molecule originating from activated eosinophil granulocytes. Biological activity and the cellular content of ECP are determined by genetic and posttranslational factors. Several single nucleotide polymorphisms (SNPs) in human ECP gene (RNASE3) have been described so...

journal_title：Biochemia medica

authors： Topic RZ,Dodig S

更新日期：2011-01-01 00:00:00

abstract：Introduction:In recent years, Six Sigma metrics has became the hotspot in all trades and professions, which contributes a general procedure to explain the performance on sigma scale. Nowadays, many large companies, such as General Healthcare, Siemens, etc., have applied Six Sigma to clinical medicine and achieved satis...

journal_title：Biochemia medica

authors： Mao X,Shao J,Zhang B,Wang Y

更新日期：2018-06-15 00:00:00

abstract：INTRODUCTION:Glycolysis affects glucose determination in vitro. The placement of sample tubes in ice-water slurry with plasma separation within 30 minutes is recommended, or alternatively the use of a glycolysis inhibitor. The aim of our two-steps study was to evaluate which Terumo tube is best for glucose determinatio...

journal_title：Biochemia medica

authors： Bonetti G,Carta M,Montagnana M,Lo Cascio C,Bonfigli AR,Mosca A,Testa R,Italian joint SIBioC-SIPMeL Study Group on Diabetes Mellitus.

更新日期：2016-01-01 00:00:00

abstract：Introduction:This study aimed to investigate the analytical bias in haematological parameters induced by storage at 33 ºC. Materials and methods:Blood from the diversion pouch of 20 blood donors were collected in K 2 EDTA vials and stored at 33 ºC. Readings from each vial ...

journal_title：Biochemia medica

authors： Jain A,Jain S,Singh N,Aswal P,Pal S,Meinia SK,Chowdhury N

更新日期：2018-06-15 00:00:00

abstract：:Peer review is widely used system for evaluating manuscripts prior to publication. It has been and still is widely used tool for making justified and fair editorial decision. However, the evidence of its efficacy is limited and it has been criticized to be time-consuming, biased, inconsistent, conservative, and open t...

journal_title：Biochemia medica

authors： Smolčić VŠ,Simundić AM

更新日期：2014-10-15 00:00:00

abstract：:With considering serum concentration of the uric acid in humans we are observing hyperuricemia and possible gout development. Many epidemiological studies have shown the relationship between the uric acid and different disorders such are obesity, metabolic syndrome, hypertension and coronary artery disease. Clinicians...

journal_title：Biochemia medica

authors： Pasalic D,Marinkovic N,Feher-Turkovic L

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Although prostatitis is a common male urinary tract infection, clinical diagnosis of prostatitis is difficult. The developmental mechanism of prostatitis is not yet unraveled which led to the elaboration of various biomarkers. As changes in asparagine-linked-(N-)-glycosylation were observed between healthy...

journal_title：Biochemia medica

authors： Vermassen T,Van Praet C,Poelaert F,Lumen N,Decaestecker K,Hoebeke P,Van Belle S,Rottey S,Delanghe J

更新日期：2015-10-15 00:00:00

abstract：Introduction:The measurement of β-hydroxybutyrate (βOHB) concentrations is a corner stone of the diagnosis of diabetic ketoacidosis and other ketonic states. The aim of this study was to perform a validation of a peripheral blood βOHB assay (Randox) on a Roche cobas c502 analyser and to establish a βOHB reference range...

journal_title：Biochemia medica

authors： Kraus FB,Kocijancic M,Kluttig A,Ludwig-Kraus B

更新日期：2020-02-15 00:00:00

abstract：:In laboratory medicine, several studies have described the most frequent errors in the different phases of the total testing process, and a large proportion of these errors occur in the pre-analytical phase. Schemes for registration of errors and subsequent feedback to the participants have been conducted for decades ...

journal_title：Biochemia medica

authors： Kristensen GB,Aakre KM,Kristoffersen AH,Sandberg S

更新日期：2014-02-15 00:00:00

abstract：:An increasing prevalence of gestational diabetes has become a very challenging task in prenatal care worldwide. International Association of Diabetes and Pregnancy Study Groups (IADPSG) has recently issued recommendations on the diagnosis and classification of hyperglycaemia in pregnancy. These recommendations, the fi...

journal_title：Biochemia medica

authors： Lovrencić MV,Honović L,Kralik S,Matica J,Prasek M,Pape-Medvidović E,Ivanisević M,Delmis J

更新日期：2013-01-01 00:00:00

abstract：:Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus (DM) and a leading cause of blindness in working-age adults in developed countries. Numerous investigations have recognised inflammation and angiogenesis as important factors in the development of this complication of ...

journal_title：Biochemia medica

authors： Kaštelan S,Orešković I,Bišćan F,Kaštelan H,Gverović Antunica A

更新日期：2020-10-15 00:00:00

abstract：INTRODUCTION:Early identification and management of chronic kidney disease (CKD) is highly cost-effective and can reduce the risk of kidney failure progression and cardiovascular disease. In 2014, the Joint Croatian Working Group (JCWG) for laboratory diagnostic of CKD on the behalf of Croatian society of medical bioch...

journal_title：Biochemia medica

authors： Biljak VR,Honović L,Matica J,Knežević B,Vojak SŠ

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Many additional tasks in the Stat laboratory (SL) increase the workload. It is necessary to control them because they can affect the service provided by the laboratory. Our aim is to calculate these tasks, study their evolution over a 10 year period, and compare turnaround times (TAT) in summer period to t...

journal_title：Biochemia medica

authors： Salinas M,López-Garrigós M,Flores E,Leiva-Salinas M,Lillo R,Leiva-Salinas C

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:In vitro human diagnostic (IVD) company recalls are a common practice aimed to either minimize a potential error or eliminate an existing failure. In this case report, we aim to provide a critical analysis of a recent IVD recall and to provide a practical framework about what to do when an IVD company reca...

journal_title：Biochemia medica

authors： Lima-Oliveira G,Lippi G,Salvagno GL,Brocco G,Guidi GC

更新日期：2015-06-05 00:00:00