Inflammatory and angiogenic biomarkers in diabetic retinopathy.

abstract：:Reliable procedures are needed to quantify the performance of instruments and methods in order to increase the quality in clinical laboratories. The Sigma metrics serves that purpose, and in the present study, the current methods for the calculation of the Sigma metrics are critically evaluated. Although the conventio...

journal_title：Biochemia medica

authors： Oosterhuis WP,Coskun A

更新日期：2018-06-15 00:00:00

abstract：INTRODUCTION:The opening of research data is emerging thanks to the increasing possibilities of digital technology. The opening of clinical trial (CT) data is a part of this process, expected to have positive scientific, ethical, health, and economic impacts thus contributing to research integrity. The January 2016 pro...

journal_title：Biochemia medica

authors： Krleža-Jerić K,Gabelica M,Banzi R,Martinić MK,Pulido B,Mahmić-Kaknjo M,Reveiz L,Šimić J,Utrobičić A,Hrgović I

更新日期：2016-10-15 00:00:00

abstract：:Eosinophil cationic protein (ECP) is a heterogeneous molecule originating from activated eosinophil granulocytes. Biological activity and the cellular content of ECP are determined by genetic and posttranslational factors. Several single nucleotide polymorphisms (SNPs) in human ECP gene (RNASE3) have been described so...

journal_title：Biochemia medica

authors： Topic RZ,Dodig S

更新日期：2011-01-01 00:00:00

abstract：Introduction:The aim of this nested study is to provide the reference intervals for already published measurements of salivary cortisol from the Croatian Adolescence Stress Study (CLASS). Material and methods:A total of 969 individuals (372 males and 597 females) were included in the reference sample (age range: 18-21...

journal_title：Biochemia medica

authors： Šupe-Domić D,Milas G,Stanišić L,Drmić Hofman I,Martinović Klarić I

更新日期：2018-02-15 00:00:00

abstract：INTRODUCTION:The usefulness and cost-effectiveness of routine laboratory preoperative tests (POTs) have been challenged recently. In fact, the American Society of Anesthesiologists (ASA) Task Force has stated that test results obtained from the medical record within 6 months of surgery generally are mostly acceptable. ...

journal_title：Biochemia medica

authors： Rodríguez-Borja E,Corchon-Peyrallo A,Aguilar-Aguilar G,Carratala-Calvo A

更新日期：2017-10-15 00:00:00

abstract：INTRODUCTION:Acute kidney injury (AKI) is common in neonatal intensive care units (NICU). In recent years, every effort is made for early detection of AKI. Our hypothesis was that serum neutrophil gelatinase-associated lipocalin (sNGAL) may be a reliable screening test for early diagnosis of AKI in premature neonates a...

journal_title：Biochemia medica

authors： Pejović B,Erić-Marinković J,Pejović M,Kotur-Stevuljević J,Peco-Antić A

更新日期：2015-10-15 00:00:00

abstract：:Accumulating evidence shows that chronic inflammation is associated to increased risk of cancer. An inflammatory component is present also in the microenvironment of tumours epidemiologically unrelated to inflammation. Extensive investigations over the past decade have uncovered many of the important mechanistic pathw...

journal_title：Biochemia medica

authors： Del Prete A,Allavena P,Santoro G,Fumarulo R,Corsi MM,Mantovani A

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Our aim was to investigate if: (a) authors of Biochemia Medica meet authorship criteria given by International Committee of Medical Journal Editors (ICMJE), (b) authorship violations are more frequent in submissions containing some type of scientific misconduct. MATERIALS AND METHODS:Self-reported authors...

journal_title：Biochemia medica

authors： Šupak-Smolčić V,Mlinarić A,Antončić D,Horvat M,Omazić J,Šimundić AM

更新日期：2015-10-15 00:00:00

abstract：:Peer review is widely used system for evaluating manuscripts prior to publication. It has been and still is widely used tool for making justified and fair editorial decision. However, the evidence of its efficacy is limited and it has been criticized to be time-consuming, biased, inconsistent, conservative, and open t...

journal_title：Biochemia medica

authors： Smolčić VŠ,Simundić AM

更新日期：2014-10-15 00:00:00

abstract：:A 51-year old male patient was admitted to the hospital with acute dyspnea and history of chronic asthma. Venous blood was drawn into a 3.0 mL heparinized syringe and delivered to the laboratory for blood gas analysis (GEM Premier 4000, Instrumentation Laboratory), which revealed high potassium value (5.2 mmol/L; refe...

journal_title：Biochemia medica

authors： Salvagno GL,Demonte D,Lippi G

更新日期：2019-02-15 00:00:00

abstract：Introduction:Macroprolactinaemia is a well-known analytical problem in diagnostics of hyperprolactinaemia usually detected with polyethylene glycol (PEG) precipitation method. Since there is no harmonization in macroprolactin detection and reporting results, this study proposes and evaluates the usefulness of in-house ...

journal_title：Biochemia medica

authors： Šostarić M,Bokulić A,Marijančević D,Zec I

更新日期：2019-06-15 00:00:00

abstract：INTRODUCTION:ISO 15189 was a new standard published in 2003 for accrediting medical laboratories. We believe that some requirements of the ISO 15189 standard are especially difficult to meet for majority of laboratories. The aim of this article was to present the frequency of nonconformities to requirements of the ISO ...

journal_title：Biochemia medica

authors： Ho B,Ho E

更新日期：2012-01-01 00:00:00

abstract：:An increasing prevalence of gestational diabetes has become a very challenging task in prenatal care worldwide. International Association of Diabetes and Pregnancy Study Groups (IADPSG) has recently issued recommendations on the diagnosis and classification of hyperglycaemia in pregnancy. These recommendations, the fi...

journal_title：Biochemia medica

authors： Lovrencić MV,Honović L,Kralik S,Matica J,Prasek M,Pape-Medvidović E,Ivanisević M,Delmis J

更新日期：2013-01-01 00:00:00

abstract：Introduction:Reference intervals (RIs) for complement assays in EDTA plasma samples have not previously been published. The objectives of the present study were to validate and/or determine RIs for classical pathway (CP50) activity and C3c, C4 and C1 inhibitor protein (C1INH) assays and to assess the need for age-speci...

journal_title：Biochemia medica

authors： Lopez B,Bertier N,Ledoult E,Joudinaud R,Maanaoui M,Majerus V,Moitrot E,Deleplancque AS,Rogeau S,Launay D,Lefèvre G,Labalette M,Dubucquoi S

更新日期：2019-10-15 00:00:00

abstract：INTRODUCTION:The aim of this work is twofold. Firstly, to study the temporal evolution in the number of laboratory requests from primary care without clinical indication, and to analyse the number of such requests before and after the implementation of an automated requesting procedure. Secondly, to investigate what ar...

journal_title：Biochemia medica

authors： Salinas M,López-Garrigós M,Flores E,Leiva-Salinas M,Esteban P,Ahumada M,Leiva-Salinas C

更新日期：2016-10-15 00:00:00

abstract：INTRODUCTION:Although prostatitis is a common male urinary tract infection, clinical diagnosis of prostatitis is difficult. The developmental mechanism of prostatitis is not yet unraveled which led to the elaboration of various biomarkers. As changes in asparagine-linked-(N-)-glycosylation were observed between healthy...

journal_title：Biochemia medica

authors： Vermassen T,Van Praet C,Poelaert F,Lumen N,Decaestecker K,Hoebeke P,Van Belle S,Rottey S,Delanghe J

更新日期：2015-10-15 00:00:00

abstract：:Extravascular body fluids (EBF) analysis can provide useful information in the differential diagnosis of conditions that caused their accumulation. Their unique nature and particular requirements accompanying EBF analysis need to be recognized in order to minimize possible negative implications on patient safety. This...

journal_title：Biochemia medica

authors： Milevoj Kopcinovic L,Culej J,Jokic A,Bozovic M,Kocijan I

更新日期：2020-02-15 00:00:00

abstract：:This systematic review presents the latest trends in salivary research and its applications in health and disease. Among the large number of analytes present in saliva, many are affected by diverse physiological and pathological conditions. Further, the non-invasive, easy and cost-effective collection methods prompt a...

journal_title：Biochemia medica

authors： Nunes LA,Mussavira S,Bindhu OS

更新日期：2015-06-05 00:00:00

abstract：:Hypothesis testing is a methodological paradigm widely popularized outside the field of pure statistics, and nowadays more or less familiar to the largest part of biomedical researchers. Conversely, the equivalence testing is still somehow obscure and misunderstood, although it represents a conceptual mainstay for som...

journal_title：Biochemia medica

authors： Ialongo C

更新日期：2017-02-15 00:00:00

abstract：INTRODUCTION:Urinary tract infection (UTI) is one of the most common bacterial infectious diseases in children. The aim of this study was to determine the total prooxidant and antioxidant capacity of children with UTI, as well as changes of oxidative status parameters according to acute inflammation persistence and acu...

journal_title：Biochemia medica

authors： Petrovic S,Bogavac-Stanojevic N,Kotur-Stevuljevic J,Peco-Antic A,Ivanisevic I,Ivanisevic J,Paripovic D,Jelic-Ivanovic Z

更新日期：2014-01-01 00:00:00

abstract：:With considering serum concentration of the uric acid in humans we are observing hyperuricemia and possible gout development. Many epidemiological studies have shown the relationship between the uric acid and different disorders such are obesity, metabolic syndrome, hypertension and coronary artery disease. Clinicians...

journal_title：Biochemia medica

authors： Pasalic D,Marinkovic N,Feher-Turkovic L

更新日期：2012-01-01 00:00:00

abstract：Introduction:Measurement of parathyroid hormone (PTH) is essential in the investigation and management of calcium metabolism disorders. To assess the significance of any assay result when clinical decision making biological variation (BV) of the measurand must be taken into consideration. The aim of the present study i...

journal_title：Biochemia medica

authors： Ercan M,Akbulut ED,Avcı E,Yücel Ç,Oğuz EF,Turhan T,Serdar M

更新日期：2019-10-15 00:00:00

abstract：Introduction:Autovalidation (AV) is an algorithm based on predefined rules designed, among others, to automate and standardize the postanalytical phase of laboratory work. The aim of this study was to examine the overall opinion of Croatian medical biochemistry laboratories regarding various aspects of AV. Material an...

journal_title：Biochemia medica

authors： Rimac V,Jokic A,Podolar S,Vlasic Tanaskovic J,Honovic L,Lenicek Krleza J

更新日期：2020-06-15 00:00:00

abstract：Introduction:Dyslipidaemia contributes to the occurrence of colorectal cancer (CRC). We hypothesized that qualitative changes of lipoproteins are associated with the risk for CRC development. This study analyses low-density lipoprotein (LDL) and high-density lipoprotein (HDL) diameters, as well as distribution of LDL a...

journal_title：Biochemia medica

authors： Stevanovic M,Vekic J,Bogavac-Stanojevic N,Janac J,Stjepanovic Z,Zeljkovic D,Trifunovic B,Spasojevic-Kalimanovska V,Zeljkovic A

更新日期：2018-10-15 00:00:00

abstract：:In this paper we would like to briefly introduce readers to the situation in the field of laboratory medicine in Bosnia and Herzegovina, with a focus on training in the field of medical biochemistry. As in some of neighboring countries, term Medical biochemist is the usual name for the Clinical biochemist or Clinical ...

journal_title：Biochemia medica

authors： Winterhalter-Jadrić M,Causević A,Jadrić R,Corić J,Hasić S,Kiseljaković E

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:In vitro human diagnostic (IVD) company recalls are a common practice aimed to either minimize a potential error or eliminate an existing failure. In this case report, we aim to provide a critical analysis of a recent IVD recall and to provide a practical framework about what to do when an IVD company reca...

journal_title：Biochemia medica

authors： Lima-Oliveira G,Lippi G,Salvagno GL,Brocco G,Guidi GC

更新日期：2015-06-05 00:00:00

abstract：INTRODUCTION:We examined the cost-effectiveness of the three different D-dimer measurements in the screening of DVT in models with and without calculation of pre-test probability (PTP) score. Moreover, we calculated the minimal cost in DVT detection. MATERIAL AND METHODS:In the group of 192 patients with clinically su...

journal_title：Biochemia medica

authors： Bogavac-Stanojević N,Dopsaj V,Jelić-Ivanović Z,Lakić D,Vasić D,Petrova G

更新日期：2013-01-01 00:00:00

abstract：Introduction:In recent years, Six Sigma metrics has became the hotspot in all trades and professions, which contributes a general procedure to explain the performance on sigma scale. Nowadays, many large companies, such as General Healthcare, Siemens, etc., have applied Six Sigma to clinical medicine and achieved satis...

journal_title：Biochemia medica

authors： Mao X,Shao J,Zhang B,Wang Y

更新日期：2018-06-15 00:00:00

abstract：INTRODUCTION:The phlebotomists' procedures are a still source of laboratory variability. The aim of this study was to verify the efficacy of minor modification in procedure for collection of diagnostic blood specimens by venipuncture from CLSI H03-A6 document is able to reduce the tourniquet application time. MATERIAL...

journal_title：Biochemia medica

authors： Lima-Oliveira G,Lippi G,Salvagno GL,Montagnana M,Picheth G,Guidi GC

更新日期：2013-01-01 00:00:00

abstract：:Preanalytical phase is the most vulnerable part of the total testing process and is considered to be among the greatest challenges to the laboratory professionals. However, preanalytical activities, management of unsuitable specimens and reporting policies are not fully standardized, nor harmonized worldwide. Several ...

journal_title：Biochemia medica

authors： Simundic AM,Lippi G

更新日期：2012-01-01 00:00:00