Additional technician tasks and turnaround time in the clinical Stat laboratory.

abstract：:Accumulating evidence shows that chronic inflammation is associated to increased risk of cancer. An inflammatory component is present also in the microenvironment of tumours epidemiologically unrelated to inflammation. Extensive investigations over the past decade have uncovered many of the important mechanistic pathw...

journal_title：Biochemia medica

authors： Del Prete A,Allavena P,Santoro G,Fumarulo R,Corsi MM,Mantovani A

更新日期：2011-01-01 00:00:00

abstract：:With considering serum concentration of the uric acid in humans we are observing hyperuricemia and possible gout development. Many epidemiological studies have shown the relationship between the uric acid and different disorders such are obesity, metabolic syndrome, hypertension and coronary artery disease. Clinicians...

journal_title：Biochemia medica

authors： Pasalic D,Marinkovic N,Feher-Turkovic L

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Acute kidney injury (AKI) is common in neonatal intensive care units (NICU). In recent years, every effort is made for early detection of AKI. Our hypothesis was that serum neutrophil gelatinase-associated lipocalin (sNGAL) may be a reliable screening test for early diagnosis of AKI in premature neonates a...

journal_title：Biochemia medica

authors： Pejović B,Erić-Marinković J,Pejović M,Kotur-Stevuljević J,Peco-Antić A

更新日期：2015-10-15 00:00:00

abstract：INTRODUCTION:Our aim was to investigate if: (a) authors of Biochemia Medica meet authorship criteria given by International Committee of Medical Journal Editors (ICMJE), (b) authorship violations are more frequent in submissions containing some type of scientific misconduct. MATERIALS AND METHODS:Self-reported authors...

journal_title：Biochemia medica

authors： Šupak-Smolčić V,Mlinarić A,Antončić D,Horvat M,Omazić J,Šimundić AM

更新日期：2015-10-15 00:00:00

abstract：Introduction:It is often quoted that 70% of clinical decisions are based on laboratory results, but the evidence to substantiate this claim is lacking. Since clinical guidelines aim to document best-practice decision making for specific disease conditions, inclusion of any laboratory test means that the best available ...

journal_title：Biochemia medica

authors： Hicks AJ,Carwardine ZL,Hallworth MJ,Kilpatrick ES

更新日期：2021-02-15 00:00:00

abstract：:Reliable procedures are needed to quantify the performance of instruments and methods in order to increase the quality in clinical laboratories. The Sigma metrics serves that purpose, and in the present study, the current methods for the calculation of the Sigma metrics are critically evaluated. Although the conventio...

journal_title：Biochemia medica

authors： Oosterhuis WP,Coskun A

更新日期：2018-06-15 00:00:00

abstract：INTRODUCTION:Early identification and management of chronic kidney disease (CKD) is highly cost-effective and can reduce the risk of kidney failure progression and cardiovascular disease. In 2014, the Joint Croatian Working Group (JCWG) for laboratory diagnostic of CKD on the behalf of Croatian society of medical bioch...

journal_title：Biochemia medica

authors： Biljak VR,Honović L,Matica J,Knežević B,Vojak SŠ

更新日期：2015-01-01 00:00:00

abstract：:Eosinophil cationic protein (ECP) is a heterogeneous molecule originating from activated eosinophil granulocytes. Biological activity and the cellular content of ECP are determined by genetic and posttranslational factors. Several single nucleotide polymorphisms (SNPs) in human ECP gene (RNASE3) have been described so...

journal_title：Biochemia medica

authors： Topic RZ,Dodig S

更新日期：2011-01-01 00:00:00

abstract：Introduction:The evaluation of patients with suspected appendicitis strives to identify all patients with presenting symptoms while minimizing negative appendectomy rate. The aim of the study was to identify the optimal combination of clinical and laboratory parameters that should facilitate the emergency department su...

journal_title：Biochemia medica

authors： Soldo I,Radisic Biljak V,Bakula B,Bakula M,Simundic AM

更新日期：2018-10-15 00:00:00

abstract：:In Croatian medical laboratories (ML), external quality assessment (EQA) has a long tradition of almost half of a century. At national level, EQA is provided by Croatian Centre for Quality Assessment in Laboratory Medicine (CROQALM) which is a part of Croatian Society of Medical Biochemistry and Laboratory Medicine.
T...

journal_title：Biochemia medica

authors： Krleza JL,Celap I,Tanaskovic JV

更新日期：2017-02-15 00:00:00

abstract：:The kappa statistic is frequently used to test interrater reliability. The importance of rater reliability lies in the fact that it represents the extent to which the data collected in the study are correct representations of the variables measured. Measurement of the extent to which data collectors (raters) assign th...

journal_title：Biochemia medica

authors： McHugh ML

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Duplicate measurements can be used to describe the performance and analytical robustness of assays and to identify outliers. We performed about 235,000 duplicate measurements of nine routinely measured quantities and evaluated the observed differences between the replicates to develop new markers for analy...

journal_title：Biochemia medica

authors： Neubig S,Grotevendt A,Kallner A,Nauck M,Petersmann A

更新日期：2017-02-15 00:00:00

abstract：INTRODUCTION:The phlebotomists' procedures are a still source of laboratory variability. The aim of this study was to verify the efficacy of minor modification in procedure for collection of diagnostic blood specimens by venipuncture from CLSI H03-A6 document is able to reduce the tourniquet application time. MATERIAL...

journal_title：Biochemia medica

authors： Lima-Oliveira G,Lippi G,Salvagno GL,Montagnana M,Picheth G,Guidi GC

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:The opening of research data is emerging thanks to the increasing possibilities of digital technology. The opening of clinical trial (CT) data is a part of this process, expected to have positive scientific, ethical, health, and economic impacts thus contributing to research integrity. The January 2016 pro...

journal_title：Biochemia medica

authors： Krleža-Jerić K,Gabelica M,Banzi R,Martinić MK,Pulido B,Mahmić-Kaknjo M,Reveiz L,Šimić J,Utrobičić A,Hrgović I

更新日期：2016-10-15 00:00:00

abstract：Introduction:Macroprolactinaemia is a well-known analytical problem in diagnostics of hyperprolactinaemia usually detected with polyethylene glycol (PEG) precipitation method. Since there is no harmonization in macroprolactin detection and reporting results, this study proposes and evaluates the usefulness of in-house ...

journal_title：Biochemia medica

authors： Šostarić M,Bokulić A,Marijančević D,Zec I

更新日期：2019-06-15 00:00:00

abstract：:An increasing prevalence of gestational diabetes has become a very challenging task in prenatal care worldwide. International Association of Diabetes and Pregnancy Study Groups (IADPSG) has recently issued recommendations on the diagnosis and classification of hyperglycaemia in pregnancy. These recommendations, the fi...

journal_title：Biochemia medica

authors： Lovrencić MV,Honović L,Kralik S,Matica J,Prasek M,Pape-Medvidović E,Ivanisević M,Delmis J

更新日期：2013-01-01 00:00:00

abstract：:Hypothesis testing is a methodological paradigm widely popularized outside the field of pure statistics, and nowadays more or less familiar to the largest part of biomedical researchers. Conversely, the equivalence testing is still somehow obscure and misunderstood, although it represents a conceptual mainstay for som...

journal_title：Biochemia medica

authors： Ialongo C

更新日期：2017-02-15 00:00:00

abstract：INTRODUCTION:The aim of this work is twofold. Firstly, to study the temporal evolution in the number of laboratory requests from primary care without clinical indication, and to analyse the number of such requests before and after the implementation of an automated requesting procedure. Secondly, to investigate what ar...

journal_title：Biochemia medica

authors： Salinas M,López-Garrigós M,Flores E,Leiva-Salinas M,Esteban P,Ahumada M,Leiva-Salinas C

更新日期：2016-10-15 00:00:00

abstract：:In laboratory medicine, several studies have described the most frequent errors in the different phases of the total testing process, and a large proportion of these errors occur in the pre-analytical phase. Schemes for registration of errors and subsequent feedback to the participants have been conducted for decades ...

journal_title：Biochemia medica

authors： Kristensen GB,Aakre KM,Kristoffersen AH,Sandberg S

更新日期：2014-02-15 00:00:00

abstract：:The Chi-square statistic is a non-parametric (distribution free) tool designed to analyze group differences when the dependent variable is measured at a nominal level. Like all non-parametric statistics, the Chi-square is robust with respect to the distribution of the data. Specifically, it does not require equality o...

journal_title：Biochemia medica

authors： McHugh ML

更新日期：2013-01-01 00:00:00

abstract：Introduction:Reference intervals (RIs) for complement assays in EDTA plasma samples have not previously been published. The objectives of the present study were to validate and/or determine RIs for classical pathway (CP50) activity and C3c, C4 and C1 inhibitor protein (C1INH) assays and to assess the need for age-speci...

journal_title：Biochemia medica

authors： Lopez B,Bertier N,Ledoult E,Joudinaud R,Maanaoui M,Majerus V,Moitrot E,Deleplancque AS,Rogeau S,Launay D,Lefèvre G,Labalette M,Dubucquoi S

更新日期：2019-10-15 00:00:00

abstract：INTRODUCTION:Glycolysis affects glucose determination in vitro. The placement of sample tubes in ice-water slurry with plasma separation within 30 minutes is recommended, or alternatively the use of a glycolysis inhibitor. The aim of our two-steps study was to evaluate which Terumo tube is best for glucose determinatio...

journal_title：Biochemia medica

authors： Bonetti G,Carta M,Montagnana M,Lo Cascio C,Bonfigli AR,Mosca A,Testa R,Italian joint SIBioC-SIPMeL Study Group on Diabetes Mellitus.

更新日期：2016-01-01 00:00:00

abstract：Introduction:Measurement of parathyroid hormone (PTH) is essential in the investigation and management of calcium metabolism disorders. To assess the significance of any assay result when clinical decision making biological variation (BV) of the measurand must be taken into consideration. The aim of the present study i...

journal_title：Biochemia medica

authors： Ercan M,Akbulut ED,Avcı E,Yücel Ç,Oğuz EF,Turhan T,Serdar M

更新日期：2019-10-15 00:00:00

abstract：INTRODUCTION:The aim of this study is to present a case of 44 years old woman with topiramate induced metabolic acidosis and kidney stones. MATERIALS AND METHODS:The laboratory features of topiramate caused renal tubular acidosis in blood and urine during topiramate treatment, with correction of metabolic acidosis by ...

journal_title：Biochemia medica

authors： Salek T,Andel I,Kurfurstova I

更新日期：2017-06-15 00:00:00

abstract：:A 51-year old male patient was admitted to the hospital with acute dyspnea and history of chronic asthma. Venous blood was drawn into a 3.0 mL heparinized syringe and delivered to the laboratory for blood gas analysis (GEM Premier 4000, Instrumentation Laboratory), which revealed high potassium value (5.2 mmol/L; refe...

journal_title：Biochemia medica

authors： Salvagno GL,Demonte D,Lippi G

更新日期：2019-02-15 00:00:00

abstract：:This systematic review presents the latest trends in salivary research and its applications in health and disease. Among the large number of analytes present in saliva, many are affected by diverse physiological and pathological conditions. Further, the non-invasive, easy and cost-effective collection methods prompt a...

journal_title：Biochemia medica

authors： Nunes LA,Mussavira S,Bindhu OS

更新日期：2015-06-05 00:00:00

abstract：:Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus (DM) and a leading cause of blindness in working-age adults in developed countries. Numerous investigations have recognised inflammation and angiogenesis as important factors in the development of this complication of ...

journal_title：Biochemia medica

authors： Kaštelan S,Orešković I,Bišćan F,Kaštelan H,Gverović Antunica A

更新日期：2020-10-15 00:00:00

abstract：INTRODUCTION:ISO 15189 was a new standard published in 2003 for accrediting medical laboratories. We believe that some requirements of the ISO 15189 standard are especially difficult to meet for majority of laboratories. The aim of this article was to present the frequency of nonconformities to requirements of the ISO ...

journal_title：Biochemia medica

authors： Ho B,Ho E

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Urinary tract infection (UTI) is one of the most common bacterial infectious diseases in children. The aim of this study was to determine the total prooxidant and antioxidant capacity of children with UTI, as well as changes of oxidative status parameters according to acute inflammation persistence and acu...

journal_title：Biochemia medica

authors： Petrovic S,Bogavac-Stanojevic N,Kotur-Stevuljevic J,Peco-Antic A,Ivanisevic I,Ivanisevic J,Paripovic D,Jelic-Ivanovic Z

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The usefulness and cost-effectiveness of routine laboratory preoperative tests (POTs) have been challenged recently. In fact, the American Society of Anesthesiologists (ASA) Task Force has stated that test results obtained from the medical record within 6 months of surgery generally are mostly acceptable. ...

journal_title：Biochemia medica

authors： Rodríguez-Borja E,Corchon-Peyrallo A,Aguilar-Aguilar G,Carratala-Calvo A

更新日期：2017-10-15 00:00:00