Principals and clinical applications of magnetic resonance cardiac spectroscopy in heart failure.

abstract：:The heart consumes huge amounts of energy to fulfil its function as a relentless pump. A highly sophisticated system of energy generation based on flexibility of substrate use and efficient energy production, effective energy sensing and energy transfer ensures function of the healthy heart across a range of physiolog...

journal_title：Heart failure reviews

authors： Siddiqi N,Singh S,Beadle R,Dawson D,Frenneaux M

更新日期：2013-09-01 00:00:00

abstract：:Diabetes mellitus is a chronic disease requiring lifelong control with hypoglycemic agents that must demonstrate excellent efficacy and safety profiles. In patients taking glucose-lowering drugs, hypoglycemia is a common cause of death associated with arrhythmias, increased thrombus formation, and specific effects of ...

journal_title：Heart failure reviews

authors： Anfinogenova Y,Grakova EV,Shvedova M,Kopieva KV,Teplyakov AT,Popov SV

更新日期：2018-05-01 00:00:00

abstract：:Sympathetic-parasympathetic interaction plays a major role in the evolution and outcome of many cardiovascular disorders. Nonetheless, a thorough understanding of this relationship and of its potential implications for prognosis and management still escapes many cardiologists. This article reviews the background of sy...

journal_title：Heart failure reviews

authors： Schwartz PJ,De Ferrari GM

更新日期：2011-03-01 00:00:00

abstract：:Objective and validated measures of depression/distress (anxiety and anger) are available and readily usable at the bedside or in clinic. Foremost among these is the Patient's Health Questionnaire--an adaptation of DSM IV criteria for Major Depressive Disorder that permits administration and scoring by nursing or phys...

journal_title：Heart failure reviews

authors： Ketterer MW,Knysz W

更新日期：2009-03-01 00:00:00

abstract：:Heart failure continues to be associated with high morbidity and mortality. Over the past decade, left ventricular assist devices have been shown to improve the survival and quality of life. However, it is quite clear that very sick patients do not do as well, and it is therefore imperative to select patients at the p...

journal_title：Heart failure reviews

authors： Gilotra NA,Russell SD

更新日期：2013-01-01 00:00:00

abstract：:Pulmonary hypertension that develops in the setting of underlying lung diseases such as COPD or idiopathic pulmonary fibrosis (IPF) is associated with decreased functional status, worsening hypoxemia and quality of life, and increased mortality. This complication of lung disease is complex in its origin and carries a ...

journal_title：Heart failure reviews

authors： Cuttica MJ

更新日期：2016-05-01 00:00:00

abstract：:There is ongoing controversy regarding the association between loop diuretics (LD), especially in high doses, and adverse clinical outcomes in outpatients with heart failure (HF). We performed a systematic review of the evidence for LD in outpatients with HF. We searched MEDLINE, EMBASE, and Cochrane Clinical Trial Co...

journal_title：Heart failure reviews

authors： Kapelios CJ,Bonou Μ,Malliaras K,Athanasiadi E,Vakrou S,Skouloudi M,Masoura C,Barbetseas J

更新日期：2020-06-21 00:00:00

abstract：:Heart failure with preserved ejection fraction (HFpEF) is a common disorder generating high mortality and important morbidity prevalence, with a very limited medical treatment available. Studies have shown that the pathophysiological hallmark of this condition is an elevated left intra-atrial pressure (LAP), exertiona...

journal_title：Heart failure reviews

authors： Burlacu A,Simion P,Nistor I,Covic A,Tinica G

更新日期：2019-09-01 00:00:00

abstract：:Stem cell therapy is a promising approach to the treatment of ischemic heart disease via replenishing cell loss after myocardial infarction. Both preclinical studies and clinical trials have indicated that cardiac function improved consistently, but very modestly after cell-based therapy. This mainly attributed to low...

journal_title：Heart failure reviews

authors： Huang P,Tian X,Li Q,Yang Y

更新日期：2016-11-01 00:00:00

abstract：:Recently, it has been suggested that erythropoietin may be useful in the treatment of cardiovascular disease, particularly heart failure. This may be by improving microvascular blood supply and ventricular function through prevention of apoptosis and angiogenesis. Promising results were seen in animals but the few, li...

journal_title：Heart failure reviews

authors： Tilling L,Clapp B

更新日期：2012-05-01 00:00:00

abstract：:The pathophysiology of heart failure (HF) is characterized by an abnormal activation of neurohumoral systems, including the sympathetic nervous and the renin-angiotensin-aldosterone systems, which have long-term deleterious effects on the disease progression. Perpetuation of this neurohumoral activation is partially d...

journal_title：Heart failure reviews

authors： Sousa-Pinto B,Ferreira-Pinto MJ,Santos M,Leite-Moreira AF

更新日期：2014-11-01 00:00:00

abstract：:The prevalence of heart failure (HF) is increasing. A distinction is made between diastolic HF (preserved left ventricular ejection fraction (LVEF)) and systolic HF (reduced LVEF). Advanced glycation end-products (AGEs) are crystallized proteins that accumulate during ageing, but are particularly increased in patients...

journal_title：Heart failure reviews

authors： Willemsen S,Hartog JW,Heiner-Fokkema MR,van Veldhuisen DJ,Voors AA

更新日期：2012-03-01 00:00:00

abstract：:Cardiac fibrosis stems from the changes in the expression of fibrotic genes in cardiac fibroblasts (CFs) in response to the tissue damage induced by various cardiovascular diseases (CVDs) leading to their transformation into active myofibroblasts, which produce high amounts of extracellular matrix (ECM) proteins leadi...

journal_title：Heart failure reviews

authors： Gorabi AM,Hajighasemi S,Kiaie N,Rosano GMC,Sathyapalan T,Al-Rasadi K,Sahebkar A

更新日期：2020-09-01 00:00:00

abstract：:It is well established that cardiac remodeling plays a pivotal role in the development of heart failure, a leading cause of death worldwide. Meanwhile, sympathetic hyperactivity is an important factor in inducing cardiac remodeling. Therefore, an in-depth understanding of beta-adrenoceptor signaling pathways would hel...

journal_title：Heart failure reviews

authors： Yang J,Liu Y,Fan X,Li Z,Cheng Y

更新日期：2014-11-01 00:00:00

abstract：:The underlying mechanism for clinical and biochemical manifestations of chronic heart failure (HF) may be due in part to neurohumoral adaptations, such as activation of the renin-angiotensin-aldosterone and sympathetic nervous systems in the periphery and the brain. Internet search and discussion with colleagues are t...

journal_title：Heart failure reviews

authors： Singh RB,Hristova K,Fedacko J,El-Kilany G,Cornelissen G

更新日期：2019-03-01 00:00:00

abstract：:Cor pulmonale is the condition in which the right ventricle undergoes morphological and/or functional changes due to diseases that affect the lungs, the pulmonary circulation, or the breathing process. Depending on the speed of onset of the pathological condition and subsequent effects on the right ventricle, it is po...

journal_title：Heart failure reviews

authors： Mandoli GE,Sciaccaluga C,Bandera F,Cameli P,Esposito R,D'Andrea A,Evola V,Sorrentino R,Malagoli A,Sisti N,Nistor D,Santoro C,Bargagli E,Mondillo S,Galderisi M,Cameli M,Working group of Echocardiography of Italian Society

更新日期：2020-08-29 00:00:00

abstract：:Cardiac hypertrophy is promoted by adrenergic over-activation and represents an independent risk factor for cardiovascular morbidity and mortality. The basic knowledge about mechanisms by which sustained adrenergic activation promotes myocardial growth, as well as understanding how structural changes in hypertrophied ...

journal_title：Heart failure reviews

authors： Osadchii OE

更新日期：2007-03-01 00:00:00

abstract：:According to previous epidemiological studies, we can reduce the thickness of epicardial fat and improve cardiovascular risk factors through exercise, and the changes may depend on the form of exercise. We systemically reviewed published studies that evaluated exercise intervention on epicardial adipose tissue (EAT) l...

journal_title：Heart failure reviews

authors： Colonetti T,Grande AJ,Amaral MC,Colonetti L,Uggioni ML,da Rosa MI,Hernandez AV,Tse G,Liu T,Nerlekar N,Biondi-Zoccai G,Neto MG,Durães AR,Pontes-Neto O,Resende ES,Roever L

更新日期：2020-05-16 00:00:00

abstract：:Dramatic advances in molecular biology dominated twentieth century biomedical science and delineated the function of individual genes and molecules in exquisite detail. However, biological processes cannot be fully understood based on the properties of individual genes and molecules alone, since these elements act in ...

journal_title：Heart failure reviews

authors： Adams KF

更新日期：2010-07-01 00:00:00

abstract：:Right ventricular (RV) diastolic dysfunction was first reported as an indicator for the assessment of ventricular dysfunction in heart failure a little over two decades ago. However, the underlying mechanisms and precise role of RV diastolic dysfunction in heart failure remain poorly described. Complexities in the str...

journal_title：Heart failure reviews

authors： Axell RG,Hoole SP,Hampton-Till J,White PA

更新日期：2015-05-01 00:00:00

abstract：:We aimed to study the cardiovascular and economic burden of diabetes mellitus (DM) in patients hospitalized for heart failure (HF) in the US and to assess the recent temporal trend. Data from the National Inpatient Sample were analyzed between 2005 and 2014. The prevalence of DM increased from 40.4 to 46.5% in patient...

journal_title：Heart failure reviews

authors： Mekhaimar M,Dargham S,El-Shazly M,Al Suwaidi J,Jneid H,Abi Khalil C

更新日期：2020-09-15 00:00:00

abstract：:Diabetes is a global epidemic and a leading cause of death with more than 422 million patients worldwide out of whom around 392 million alone suffer from type 2 diabetes (T2D). Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are novel and effective drugs in managing glycemia of T2D patients. These inhibitors gained...

journal_title：Heart failure reviews

authors： Kaplan A,Abidi E,El-Yazbi A,Eid A,Booz GW,Zouein FA

更新日期：2018-05-01 00:00:00

abstract：:Descriptions of the pathophysiology of heart failure have gone through a substantial evolution in the last 50 years. It is now recognised that heart failure can occur in the presence and also in the absence of a reduction in left ventricular function. In the former situation, this classically has been described to lea...

journal_title：Heart failure reviews

authors： Dorhout Mees EJ

更新日期：2013-07-01 00:00:00

abstract：:Congestive heart failure is most often caused by scar from coronary occlusion. The transition from occluded vessel to scar to dilation results in a remodeled ventricle that changes shape from ellipse to sphere. This shape change following an index event is called remodeling and a surgical approach for restoration (bri...

journal_title：Heart failure reviews

authors： Buckberg GD

更新日期：2004-10-01 00:00:00

abstract：:The prognosis for patients with congestive heart failure (CHF) has been improved as a result of the use of angiotensin converting enzyme inhibitors and beta-adrenergic receptor blockers. The success of these therapies underscores the pathogenic role of neurohormonal activation in CHF. Clinical and experimental evidenc...

journal_title：Heart failure reviews

authors： Kan H,Finkel MS

更新日期：2001-03-01 00:00:00

abstract：:Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, life-threatening disease characterized by deposition of insoluble amyloid fibrils in the myocardium, resulting in cardiac structural and functional abnormalities and ultimately heart failure. Disease frequency is reportedly lower in women than men, but s...

journal_title：Heart failure reviews

authors： Bruno M,Castaño A,Burton A,Grodin JL

更新日期：2021-01-01 00:00:00

abstract：:Important changes occur in the cardiovascular system with advancing age, even in apparently healthy individuals. Thickening and stiffening of the large arteries develop due to collagen and calcium deposition and loss of elastic fibers in the medial layer. These arterial changes cause systolic blood pressure to rise wi...

journal_title：Heart failure reviews

authors： Fleg JL,Strait J

更新日期：2012-09-01 00:00:00

abstract：:Cardiac hypertrophy (CH) is generally considered adaptive responses that may occur after myocardial infarction, pressure overload, volume overload, inflammatory heart muscle disease, or idiopathic dilated cardiomyopathy, whereas long-term stimulation eventually leads to heart failure (HF). However, the current molecul...

journal_title：Heart failure reviews

authors： Sun J,Wang C

更新日期：2020-11-01 00:00:00

abstract：:Due to the recent advances in diagnosis and management of patients with HER2-positive breast cancer, especially through novel HER2-targeted agents, cardiotoxicity becomes an emerging problem. Although chemotherapy significantly increases survival, the risk of cardiovascular disease development is high and still undere...

journal_title：Heart failure reviews

authors： Gonciar D,Mocan L,Zlibut A,Mocan T,Agoston-Coldea L

更新日期：2021-01-06 00:00:00

abstract：:There are multiple intrinsic mechanisms for diastolic dysfunction ranging from molecular to structural derangements in ventricular myocardium. The molecular mechanisms regulating the progression from normal diastolic function to severe dysfunction still remain poorly understood. Recent studies suggest a potentially im...

journal_title：Heart failure reviews

authors： Mikhailov AT,Torrado M

更新日期：2016-11-01 00:00:00