Endoscopic Management of Pancreatic Cysts.

abstract：:It is known that the muscularis mucosae and mucosa are not pharmacologically homogeneous throughout the rat colon. The aim of this study was to simultaneously characterize all three neurokinin (NK) receptors in the muscularis mucosae and mucosa along the length of the rat colon. Strips of proximal, mid, and distal col...

journal_title：Digestive diseases and sciences

authors： Appleyard CB,Morales M,Percy WH

更新日期：2006-03-01 00:00:00

abstract：:Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited. This study evaluates screening FS in subjects > or = 75 years of age (elderly) compared with ages 50-74 years (general screening population). Data were collected on patient characteristics, insertion depth, procedural di...

journal_title：Digestive diseases and sciences

authors： Pabby A,Suneja A,Heeren T,Farraye FA

更新日期：2005-11-01 00:00:00

abstract：:The aims of this study were to determine the impact of irritable bowel syndrome on quality of life using a well-standardized measure, the SF-36, and to determine whether apparent impairments may be due to neuroticism. Undergraduate students with irritable bowel syndrome who had consulted a physician (41 females, 42 ma...

journal_title：Digestive diseases and sciences

authors： Whitehead WE,Burnett CK,Cook EW 3rd,Taub E

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Dextran sodium sulphate (DSS) is commonly used to induce intestinal inflammation in rodents. Despite its continuing importance as a model system for examining IBD pathogenesis, the mucosal and systemic immune responses have not been comprehensively documented. AIMS:The purpose of this study was to dissect f...

journal_title：Digestive diseases and sciences

authors： Hall LJ,Faivre E,Quinlan A,Shanahan F,Nally K,Melgar S

更新日期：2011-01-01 00:00:00

abstract：:Zinc is an essential trace element, exerting important antioxidant, anti-inflammatory, and antiapoptotic effects. It affects growth and development and participates in processes such as aging and cancer induction. The liver is important for the regulation of zinc homeostasis, while zinc is necessary for proper liver f...

journal_title：Digestive diseases and sciences

authors： Stamoulis I,Kouraklis G,Theocharis S

更新日期：2007-07-01 00:00:00

abstract：:Growth factors upregulate cyclooxygenase-2 (COX-2) expression and extracellular signal-regulated kinase (ERK) activity, yet little is known regarding the interaction between COX-2 and ERK in terms of mitogenic signal transduction pathways in gastric epithelial cells. Therefore, we examined the role of COX-2 in EGF-ind...

journal_title：Digestive diseases and sciences

authors： Sasaki E,Tominaga K,Watanabe T,Fujiwara Y,Oshitani N,Matsumoto T,Higuchi K,Tarnawski AS,Arakawa T

更新日期：2003-12-01 00:00:00

abstract：:Prevalence estimates for irritable bowel syndrome from surveys in Western countries are 4.4% to 22%, generally higher in women than men, and only a minority seek health care. There are few studies of bowel patterns in Asian countries. We conducted a survey of a nonpatient population in Ho Chi Minh City, Vietnam, to de...

journal_title：Digestive diseases and sciences

authors： Zuckerman MJ,Nguyen G,Ho H,Nguyen L,Gregory GG

更新日期：2006-05-01 00:00:00

abstract：:Eosinophilic gastroenteritis is a rare benign disease characterized by tissue eosinophilic infiltration that may involve several digestive tract layers. Also known as allergic, or eosinophilic allergic, gastroenteropathy, it usually involves the stomach and small intestine: rarely the colon. It may or may not be accom...

journal_title：Digestive diseases and sciences

authors： Méndez-Sánchez N,Chávez-Tapia NC,Vazquez-Elizondo G,Uribe M

更新日期：2007-11-01 00:00:00

abstract：:Patients affected by diabetes mellitus are reported to have an increased incidence of gallbladder abnormalities. The pathophysiologic mechanisms for this phenomenon are unclear. In the present study ultrasonography was used to determine gallbladder emptying in response to a meal or separate cephalic or hormonal stimul...

journal_title：Digestive diseases and sciences

authors： Fiorucci S,Bosso R,Scionti L,DiSanto S,Annibale B,Delle Fave G,Morelli A

更新日期：1990-09-01 00:00:00

abstract：:This study set out to evaluate the effects of dietary fiber on cancer development in the large bowel under in vivo experimental conditions as similar as possible to those under which this cancer develops in vivo in humans. Forty-eight Sprague-Dawley rats were divided into three groups that were fed either a nonfiber d...

journal_title：Digestive diseases and sciences

authors： Iwane S,Nakaji S,Ohta M,Tamura K,Sakamoto J,Munakata A,Sugawara K

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Suppressive activity of recurrence by interferon-free direct-acting antivirals (DAA) is not elucidated after curative treatment of hepatocellular carcinoma (HCC). PATIENTS AND METHODS:A total of 177 patients received DAA after curative manners of HCC: 89 patients underwent DAA therapy after initial HCC trea...

journal_title：Digestive diseases and sciences

authors： Ikeda K,Kawamura Y,Kobayashi M,Kominami Y,Fujiyama S,Sezaki H,Hosaka T,Akuta N,Saitoh S,Suzuki F,Suzuki Y,Arase Y,Kumada H

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Biosimilar approval, such as Inflectra™ (CT-P13) for treating ulcerative colitis (UC) and Crohn's disease (CD), has reduced direct drug costs. Though clinicians are comfortable with biosimilar use in treatment-naïve patients, there are concerns in some jurisdictions that there are insufficient data ...

journal_title：Digestive diseases and sciences

authors： Bernard EJ,Fedorak RN,Jairath V

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Hepatic encephalopathy is a syndrome whose physiopathology is poorly understood; therefore, current diagnostic tests are imperfect and modern therapy is nonspecific. Particularly, it has been suggested that inflammation plays an important role in the pathogenesis of portal hypertensive encephalopathy in the ...

journal_title：Digestive diseases and sciences

authors： Merino J,Aller MA,Rubio S,Arias N,Nava MP,Loscertales M,Arias J,Arias JL

更新日期：2011-08-01 00:00:00

abstract：:In addition to cholecystokinin, other hormones have been suggested to be involved in regulation of postprandial gallbladder contraction. We aimed to evaluate effects of growth hormone (GH) on gallbladder contractility and cholecystokinin release. Gallbladder and gastric emptying (by ultrasound) and cholecystokinin rel...

journal_title：Digestive diseases and sciences

authors： Moschetta A,Twickler TB,Rehfeld JF,van Ooteghem NA,Cabezas MC,Portincasa P,van Berge-Henegouwen GP,van Erpecum KJ

更新日期：2004-03-01 00:00:00

abstract：:On-demand therapy is effective for maintaining symptoms control in nonerosive gastroesophageal reflux disease (GERD). Our aim was to assess the clinical effectiveness of on-demand therapy with a proton pump inhibitor (PPI) in mild GERD (nonerosive and low-grade esophagitis), its impact on health-related quality of lif...

journal_title：Digestive diseases and sciences

authors： Ponce J,Argüello L,Bastida G,Ponce M,Ortiz V,Garrigues V

更新日期：2004-06-01 00:00:00

abstract：:Intravenous administration of platelet-activating factor (PAF) induces extensive damage in rat gastric mucosa. The aim of the present study was to examine whether the presence or absence of acid in the gastric lumen could modify the PAF-induced gastric damage. The effects of inhibition of basal and pentagastrin-stimul...

journal_title：Digestive diseases and sciences

authors： Piqué JM,Pérez Ayuso RM,Bilbao J,Terés J

更新日期：1991-12-01 00:00:00

abstract：:Antagonists of nitric oxide synthesis inhibit nerve-induced hyperpolarization and relaxation of muscle from the opossum lower esophageal sphincter. These studies test the hypothesis that nitric oxide is released during stimulation of intrinsic esophageal nerves. The intrinsic nerves were stimulated with an electrical ...

journal_title：Digestive diseases and sciences

authors： Murray J,Bates JN,Conklin JL

更新日期：1994-09-01 00:00:00

abstract：:The aim of this study was to examine the seroprevalence of antibody to CagA antigen, as well as other major H. pylori antigens by Western blot in H. pylori-infected subjects with endoscopically normal mucosa (N = 54) and duodenal ulcer (N = 51). The role of the host and environmental factors was also evaluated. There ...

journal_title：Digestive diseases and sciences

authors： Chen TS,Chang FY,Lee SD

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Oxaliplatin is one of the most effective chemotherapeutic drugs used for the treatment of colorectal cancer (CRC). However, intervention that attenuates the resistance of oxaliplatin is still required in the treatment of CRC. AIMS:To investigate the role of miR-325 in changing the oxaliplatin sensitivity to...

journal_title：Digestive diseases and sciences

authors： Zhang L,Chen H,Song Y,Gu Q,Zhang L,Xie Q,Xu J,Zhang M

更新日期：2020-09-10 00:00:00

abstract：:The protective effect of a human strain of Bifidobacterium bifidum (B. bifidum) against murine group A rotavirus (MRV) was examined in the intestines of BALB/c infected mice. In experiments designed to determine whether B. bifidum mediated MRV shedding during diarrheal disease, pregnant dams (and their expected litter...

journal_title：Digestive diseases and sciences

authors： Duffy LC,Zielezny MA,Riepenhoff-Talty M,Dryja D,Sayahtaheri-Altaie S,Griffiths E,Ruffin D,Barrett H,Ogra PL

更新日期：1994-11-01 00:00:00

abstract：:Immune (gamma) interferon is a substance produced by immunologically activated mononuclear cells. Besides its antiviral activity, interferon gamma has a crucial role in immunoregulation, by acting directly upon lymphocytes and monocytes, and interacting with other soluble mediators of the immune response. Studies of t...

journal_title：Digestive diseases and sciences

authors： Lieberman BY,Fiocchi C,Youngman KR,Sapatnekar WK,Proffitt MR

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Prior studies have shown poor compliance with quality measures for IBD at academic and private practices. We sought to provide focused interventions to improve compliance and documentation with the IBD measures. METHODS:Two centers, academic practice (AP) and private practice (PP), initially reviewed their ...

journal_title：Digestive diseases and sciences

authors： Feuerstein JD,Papamichael K,Popejoy S,Nadelson A,Lewandowski JJ,Geissler K,Martinez-Vazquez M,Leffler DA,Ariyabuddhiphongs K,Thukral C,Cheifetz AS

更新日期：2018-01-01 00:00:00

abstract：:Ornithine decarboxylase (ODC) activity has been associated with mucosal growth and injury, yet, little information is available on ODC activity during gastric ulcer healing. We measured ODC activity in the ulcer base submucosa and the surrounding mucosa at 1 cm and 2 cm and assessed ulcer surface healing and a histolo...

journal_title：Digestive diseases and sciences

authors： Marcuard SP,Silverman JF,Finley JL,Seidel ER

更新日期：1992-07-01 00:00:00

abstract：:Sonic Hedgehog (Shh) signaling has been extensively studied for its role in developmental biology and cancer biology. The association between Shh and cancer development in general is well established but the functional role of Shh in the development and progression of gastric cancer specifically is largely unknown. Bo...

journal_title：Digestive diseases and sciences

authors： Martin J,Donnelly JM,Houghton J,Zavros Y

更新日期：2010-06-01 00:00:00

abstract：:We have previously reported impressive results in using a gonadotropin-releasing hormone analog, leuprolide acetate (Lupron), in the treatment of moderate to severe symptoms (especially abdominal pain and nausea) in patients with functional bowel disease (FBD). Pain is the hallmark of patients with FBD, and there is n...

journal_title：Digestive diseases and sciences

authors： Mathias JR,Clench MH,Abell TL,Koch KL,Lehman G,Robinson M,Rothstein R,Snape WJ

更新日期：1998-06-01 00:00:00

abstract：:Previous studies showed that bile salts had a promoting effect on colon cancer development and this effect was inhibited by ursodeoxycholate (UDC). We recently found that both human colorectal adenomas and carcinomas were associated with a specific decrease in alkaline sphingomyelinase activity. In this work, we compa...

journal_title：Digestive diseases and sciences

authors： Duan RD,Cheng Y,Tauschel HD,Nilsson A

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Fecal Occult Blood Test (FOBT) is an accepted screening test for colorectal cancer (CRC). It has been shown to decrease mortality by up to 30%. The outcome of screening failures has not been adequately studied. AIMS:The purpose of this study was to assess the outcome of patients who were diagnosed with CRC ...

journal_title：Digestive diseases and sciences

authors： Half EE,Mlynarsky L,Naftali T,Benjaminov F,Konikoff FM

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Notch signaling is required for the maintenance of intestinal epithelial proliferation. Dysfunction of this signaling pathway is associated with the loss of proliferated crypt epithelial cells. AIM:The aim of this study was to investigate the role of Notch signaling in small bowel resection (SBR)-associated...

journal_title：Digestive diseases and sciences

authors： Chen G,Sun L,Yu M,Meng D,Wang W,Yang Y,Yang H

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Capsule endoscopy (CE) has the problem that lumen visualization is impaired by bubbles, bile, and debris. The benefits of bowel preparation are still controversial and the best method remains to be determined. The objective of this study was to evaluate the effect of the method of bowel preparation ...

journal_title：Digestive diseases and sciences

authors： Park SC,Keum B,Seo YS,Kim YS,Jeen YT,Chun HJ,Um SH,Kim CD,Ryu HS

更新日期：2011-06-01 00:00:00

abstract：:Glutamine synthetase is responsible for the ATP-dependent amidation of glutamate to glutamine. In liver the enzyme is highly localized in perivenous hepatocytes; in brain the enzyme is localized in astrocytes. Portacaval anastomosis resulted in liver atrophy, hyperammonemia, and up to 90% loss of glutamine synthetase ...

journal_title：Digestive diseases and sciences

authors： Girard G,Butterworth RF

更新日期：1992-07-01 00:00:00