Characterization of a competitive and reversible ligand to E2 conformation of Na, K ATPase molecule.

abstract：:The isolation and characterization of cofactor-independent phosphoglycerate mutase gene from maize (Zea mays) is here reported. This gene sequence constitutes the first described from this enzyme. The gene spans 5.4 kilo base pairs and has nine exons in the translated region. Canonical TATA and CCAAT and Sp1-like boxe...

journal_title：Biochemical and biophysical research communications

authors： Pérez de la Ossa P,Graña X,Ruiz-Lozano P,Climent F

更新日期：1994-09-15 00:00:00

abstract：:Sorbitol levels in proximal tubule cells cultured for 96 h in the presence of 16.5 mM and 27.5 mM glucose were significantly elevated when compared to cells cultured in 5.5 mM glucose. No changes in the levels of aldose reductase activity, mRNA and immunoreactivity were observed in cells cultured for up to 168 h in me...

journal_title：Biochemical and biophysical research communications

authors： Petrash JM,Flath M,Sens D,Bylander J

更新日期：1992-08-31 00:00:00

abstract：:The HSP30 gene of the budding yeast Saccharomyces cerevisiae encodes a seven-transmembrane heat shock protein expressed in response to various types of stress including heat shock. Although Hsp30p contains a potential N-glycosylation consensus sequence (Asn(2)-Asp(3)-Thr(4)), whether it is actually N-glycosylated has ...

journal_title：Biochemical and biophysical research communications

authors： Kamo K,Takabatake A,Inoue Y,Izawa S

更新日期：2012-03-30 00:00:00

abstract：:We have examined the role of K+ channels in mediating vasorelaxation produced by bacterial lipopolysaccharide (LPS) in endothelial-denuded strips of rat aorta precontracted with phenylephrine (1 microM). Salmonella typhosa LPS (0.1 microgram/ml) caused significant relaxation of tension which peaked at approximately 4h...

journal_title：Biochemical and biophysical research communications

authors： Hall S,Turcato S,Clapp L

更新日期：1996-07-05 00:00:00

abstract：:Lactobacillus, a representative useful bacterium, in the intestinal tract was found to bind to some specific glycosphingolipids, like the pathogenic intestinal bacteria. Thin layer chromatography overlay assays using rabbit antiserum against Lactobacillus casei revealed that the bacteria bound to GA1 and trihexosylcer...

journal_title：Biochemical and biophysical research communications

authors： Yamamoto K,Miwa T,Taniguchi H,Nagano T,Shimamura K,Tanaka T,Kumagai H

更新日期：1996-11-01 00:00:00

abstract：:Integrins alpha(M)beta(2) plays important role on leukocytes, such as adhesion, migration, phagocytosis, and apoptosis. It was hypothesized that homomeric associations of integrin subunits provide a driving force for integrins activation, and simultaneously inducing the formation of integrins clusters. However, experi...

journal_title：Biochemical and biophysical research communications

authors： Fu G,Wang C,Wang GY,Chen YZ,He C,Xu ZZ

更新日期：2006-12-29 00:00:00

abstract：:c-Raf-1 is a serine/threonine-specific protein kinase which is regulated by phosphorylation. A putative c-AMP dependent protein kinase PKA phosphorylation site with the consensus sequence RRXS, Ser43, and a predominant phosphorylation site of c-Raf-1, Ser259, can be phosphorylated by PKA in vitro as shown by compariso...

journal_title：Biochemical and biophysical research communications

authors： Schramm K,Niehof M,Radziwill G,Rommel C,Moelling K

更新日期：1994-06-15 00:00:00

abstract：:Sphingosine 1-phosphate (S1P) has recently been described to induce antimycobacterial activity. The present study analyses the role played by S1P in antigen presentation of monocytes and in the next activation of Mycobacterium tuberculosis (MTB)-specific CD4+ T cell response. Results reported herein show that S1P stim...

journal_title：Biochemical and biophysical research communications

authors： Santucci MB,Greco E,De Spirito M,Arcovito G,De Angelis G,Cauda R,Fraziano M

更新日期：2007-09-28 00:00:00

abstract：:Calcium/calmodulin-dependent protein kinase II (CaM KII) is thought to be involved in the majority of the neuronal functions mediated by intracellular free Ca(2+), and has been implicated in long-term potentiation, learning, and memory. In this work, we have examined in detail the RNA expression pattern for the Drosop...

journal_title：Biochemical and biophysical research communications

authors： Rachidi M,Lopes C,Takamatsu Y,Ohsako S,Benichou JC,Delabar JM

更新日期：1999-07-14 00:00:00

abstract：:Peptide array consisting of hundreds of peptides spatially addressed and synthesized on a cellulose membrane support was used to screen ligand-inhibitory peptides. As a model, angiotensin II (Ang II), a significant peptide related to the treatment of cardiovascular diseases, was chosen as the target ligand. Peptide ar...

journal_title：Biochemical and biophysical research communications

authors： Kato R,Kunimatsu M,Fujimoto S,Kobayashi T,Honda H

更新日期：2004-02-27 00:00:00

abstract：:We report the cloning and characterization of both the cDNA (tufA) and genomic clones encoding for a chloroplast translation elongation factor (EF-Tu) from pea. The analysis of the deduced amino acids of the cDNA clone reveals the presence of putative transit peptide sequence and four GTP binding domains and two EF-Tu...

journal_title：Biochemical and biophysical research communications

authors： Singh BN,Mishra RN,Agarwal PK,Goswami M,Nair S,Sopory SK,Reddy MK

更新日期：2004-07-23 00:00:00

abstract：:Even though earlier reports have revealed that Aquaporin 8 (AQP8) exert essential roles in diverse malignancies, its relationship between specific microRNAs (miRNAs) in regulation of colorectal carcinoma (CRC) progression has never been elaborated. Herein, we proved that AQP8 was downregulated in CRC and high level of...

journal_title：Biochemical and biophysical research communications

authors： Zhang H,Du WB,Guo XM,Wang LK,Cheng JM,Wei LJ

更新日期：2020-06-18 00:00:00

abstract：:Fungi, particularly the white rot basidiomycetes, have an extraordinary capability to degrade and/or mineralize (to CO(2)) the recalcitrant fused-ring high molecular weight (4 aromatic-rings) polycyclic aromatic hydrocarbons (HMW PAHs). Despite over 30years of research demonstrating involvement of P450 monooxygenation...

journal_title：Biochemical and biophysical research communications

authors： Syed K,Doddapaneni H,Subramanian V,Lam YW,Yadav JS

更新日期：2010-09-03 00:00:00

abstract：:A fast and robust assay, based on the combination of the highly sensitive immuno-PCR (IPCR), employing standardized self-assembled DNA-protein conjugates as reagents, and the well-established, reliable, and fast real-time PCR detection by means of the TaqMan principle is introduced in this work. The use of anti-specie...

journal_title：Biochemical and biophysical research communications

authors： Adler M,Wacker R,Niemeyer CM

更新日期：2003-08-22 00:00:00

abstract：:Stimulation of human T cell line Jurkat results in rapid tyrosine phosphorylation of a 35-38 kDa protein that is found in large and buoyant detergent-resistant membrane microdomains containing also glycosylphosphatidylinositol (GPI)-anchored proteins, glycolipids and Src-family protein tyrosine kinases ("GPI-microdoma...

journal_title：Biochemical and biophysical research communications

authors： Brdiĉka T,Cerný J,Horejŝí V

更新日期：1998-07-20 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and often fatal pulmonary disorder, and its pathology is characterized by parenchymal fibrosis. To investigate the characteristics of fibroblasts in IPF, we obtained eight fibroblast cell lines from lungs with IPF and eight lines from normal lungs. We foun...

journal_title：Biochemical and biophysical research communications

authors： Shoda H,Yokoyama A,Nishino R,Nakashima T,Ishikawa N,Haruta Y,Hattori N,Naka T,Kohno N

更新日期：2007-02-23 00:00:00

abstract：:The posttranscriptional RNA editing by the type 1 adenosine deaminase acting on RNAs (ADAR1), expressed as p110 and p150 isoforms, is important for both physiological and pathological processes. Their expression and significance in leukemias remain unknown. Here, we investigated the expression of ADAR1 in Chinese pedi...

journal_title：Biochemical and biophysical research communications

authors： Ma CH,Chong JH,Guo Y,Zeng HM,Liu SY,Xu LL,Wei J,Lin YM,Zhu XF,Zheng GG

更新日期：2011-03-11 00:00:00

abstract：:Many studies have been reported that tripartite motif-containing (TRIM) proteins play important roles in various cellular processes and involved in many diseases. TRIM3, a member of TRIM family, has been proved that it plays important roles in various cancers. Nevertheless, its effects on cervical cancer reminded unkn...

journal_title：Biochemical and biophysical research communications

authors： Song Y,Guo Q,Gao S,Hua K

更新日期：2018-04-06 00:00:00

abstract：:G-quadruplex is one of the best-studied non-B type DNA that is now known to be prevalently present in the genomes of almost all the biological species. Recent studies reveal roles of G-quadruplex (G4) structures in various nucleic acids and chromosome transactions. In this short article, we will first describe recent ...

journal_title：Biochemical and biophysical research communications

authors： Masai H,Tanaka T

更新日期：2020-10-08 00:00:00

abstract：:DNase coatings show great potential to prevent biofilm formation in various applications of the medical implant, food and marine industry. However, straightforward and quantitative methods to characterize the enzymatic activity of these coatings are currently not available. We here introduce the qDNase assay, a quanti...

journal_title：Biochemical and biophysical research communications

authors： Van der Gucht M,Aktan MK,Hendrix H,Velde GV,Paeshuyse J,Braem A,Lavigne R

更新日期：2021-01-01 00:00:00

abstract：:Licorice is a popular medicinal plant, and it has been used to treat various diseases, including liver diseases. Glycycoumarin (GCM) is a major coumarin compound isolated from licorice with favorable bioavailability property. Our previous studies have shown that GCM is capable of inhibiting lipoapoptosis in both cell ...

journal_title：Biochemical and biophysical research communications

authors： Zhang E,Yin S,Zhao C,Fan L,Hu H

更新日期：2020-07-12 00:00:00

abstract：:Diabetic retinopathy (DR) is the leading cause of vision loss among working-age populations in developed countries. Current treatment options are limited to tight glycemic, blood pressure control and destructive laser surgery. Carbonic anhydrases (CAs) are a group of enzymes involving in the rapid conversion of carbon...

journal_title：Biochemical and biophysical research communications

authors： Weiwei Z,Hu R

更新日期：2009-12-18 00:00:00

abstract：:Runt-related transcription factor-2 (RUNX2)/core binding factor a1 (Cbfa1) is implicated in the regulation of osteoblast differentiation and osteoblast-specific gene expression. Mutations in RUNX2 cause the bone disease cleidocranial dysplasia, which is characterized by multiple skeletal defects. RUNX2 is expressed as...

journal_title：Biochemical and biophysical research communications

authors： Sudhakar S,Li Y,Katz MS,Elango N

更新日期：2001-11-30 00:00:00

abstract：:Membrane rafts are small and dynamic regions enriched in sphingolipids, cholesterol, ganglioside GM1 and protein markers like flotillins, forming the flatter domains or caveolins, which are characterized as stable flask-shape invaginations. We explored whether membrane rafts participate in the entry of Trypanosoma cru...

journal_title：Biochemical and biophysical research communications

authors： Barrias ES,Dutra JM,De Souza W,Carvalho TM

更新日期：2007-11-23 00:00:00

abstract：:Pro-inflammatory cytokines contribute to pancreatic beta cell death in the pathogenesis of type 1 diabetes mellitus (DM). Cytochrome P450-derived epoxyeicosatrienoic acids (EETs), produced by selective epoxidation of arachidonic acid, display anti-inflammatory activity in numerous disease models, in part through inhib...

journal_title：Biochemical and biophysical research communications

authors： Grimes D,Watson D

更新日期：2019-12-03 00:00:00

abstract：:Type I protein arginine N-methyltransferases catalyze the formation of omega-NG-monomethylarginine and asymmetric omega-NG, NG-dimethylarginine residues using S-adenosyl-l-methionine as the methyl donor. In vitro these enzymes can modify a number of soluble methyl-accepting substrates in yeast and mammalian cell extra...

journal_title：Biochemical and biophysical research communications

authors： Frankel A,Clarke S

更新日期：1999-06-07 00:00:00

abstract：:Human prostasin was recently identified as a potential regulator of epithelial sodium channel (ENaC) function. Through the use of positional scanning combinatorial substrate libraries, prostasin was shown to have a preference for poly-basic substrates: in position P4 preference was for arginine or lysine; in P3 prefer...

journal_title：Biochemical and biophysical research communications

authors： Shipway A,Danahay H,Williams JA,Tully DC,Backes BJ,Harris JL

更新日期：2004-11-12 00:00:00

abstract：:Mammalian X and Y chromosomes evolved from a pair of autosomes. Although most ancestral genes have been lost from the Y chromosome, a small number of ancestral X-Y gene pairs are still present on the sex chromosomes. The KDM5C and KDM5D genes, which encode H3K4 histone demethylases, are a surviving ancestral gene pair...

journal_title：Biochemical and biophysical research communications

authors： Kosugi M,Otani M,Kikkawa Y,Itakura Y,Sakai K,Ito T,Toyoda M,Sekita Y,Kimura T

更新日期：2020-02-17 00:00:00

abstract：:SecB, a molecular chaperone in Escherichia coli, binds a subset of precursor proteins that are exported across the plasma membrane via the Sec pathway. Previous studies showed that SecB bound directly to the mature region rather than to the signal sequence of the precursor protein. To determine the binding pattern of ...

journal_title：Biochemical and biophysical research communications

authors： Tang Y,Pan X,Tai PC,Sui SF

更新日期：2010-03-19 00:00:00

abstract：:A ferric low-spin species with an anomalously small g3-g1 separation generated by the reaction of Fe(III)tetraphenylporphyrin with t-butylhydroperoxide in the presence of tatramethylammonium hydroxide was characterized by ESR spectroscopy. The reaction kinetics, investigated by monitoring ESR intensity, indicated that...

journal_title：Biochemical and biophysical research communications

authors： Tajima K,Ishizu K,Sakurai H,Ohya-Nishiguchi H

更新日期：1986-03-28 00:00:00