Abstract:
BACKGROUND/AIMS:Although laparoscopic fundoplication is a well-established therapy for gastroesophageal reflux disease (GERD) in Western countries, the mainstay of GERD treatment in Korea is long-term proton pump inhibitor (PPI) use. The aim of the present study was to evaluate nationwide data regarding antireflux surgery in Korea. METHODS:Data from 2011 to 2014 were collected from the Korean Antireflux Surgery Study Group and then analyzed. RESULTS:A total of 87 patients underwent laparoscopic fundoplication for the treatment of GERD. Preoperatively, typical symptoms were present in 81 patients (93%) and atypical symptoms were present in 51 patients (59%). Twenty-seven patients (31%) had poor PPI responses. The average surgical time and postoperative hospital stay were 116.3±42.3 minutes and 4.3±3.1 days, respectively. At 3 months after surgery, typical symptoms were completely controlled in 86.3% of patients and partially controlled in 11.7%, whereas atypical symptoms were completely controlled in 63.3% of patients and partially controlled in 23.3%. CONCLUSIONS:This study showed that although atypical symptoms and PPI nonresponders are common, the complete control rates of typical and atypical symptoms were 86.3% and 63.3%, respectively. Laparoscopic fundoplication is an efficacious method of controlling the symptoms of GERD and has an acceptable rate of postoperative morbidity and adverse symptoms.
journal_name
Gut Liverjournal_title
Gut and liverauthors
Lee JH,Park JM,Han SU,Kim JJ,Song KY,Ryu SW,Seo KW,Kim HI,Kim W,Korean Antireflux Surgery Study (KARS) Group.doi
10.5009/gnl15406subject
Has Abstractpub_date
2016-09-15 00:00:00pages
726-30issue
5eissn
1976-2283issn
2005-1212pii
gnl15406journal_volume
10pub_type
杂志文章相关文献
Gut and Liver文献大全abstract::The advent of biologics and biologic therapy has transformed the management of inflammatory bowel disease (IBD) with enhanced early and adequate responses to treatment, fewer hospitalizations, a reduced need for surgery, and unprecedented outcomes including complete mucosal and histologic healing. However, an importan...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl19209
更新日期:2020-11-15 00:00:00
abstract:BACKGROUND/AIMS:Although gastric hyperplastic polyps are usually considered as benign lesions, a low risk of carcinomatous conversion is currently recognized. We aimed to identify the characteristics of hyperplastic polyps undergoing neoplastic transformation. METHODS:A total of 269 gastric hyperplastic polyps from 21...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2009.3.4.271
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND/AIMS:The usefulness of immunohistochemistry to screen for the microsatellite instability (MSI) phenotype in gastric cancer remains unclear. Moreover, the prognostic value of MSI phenotypes in gastric cancer has been debated. METHODS:The clinicopathologic parameters and survival outcomes of 203 MSI-high (MSI...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl15133
更新日期:2015-09-23 00:00:00
abstract:BACKGROUND/AIMS:Patients with cholangiocarcinoma usually present at an advanced stage, and more than 50% of cases are not resectable at the time of diagnosis. Recently, photodynamic therapy (PDT) has been proposed as a palliative and neoadjuvant modality. We evaluated whether combination of PDT and chemotherapy is more...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2014.8.3.318
更新日期:2014-05-01 00:00:00
abstract:Background/Aims:Although gastric cancer (GC) prevalence in the United States overall is low, there is significantly elevated risk in certain racial/ethnic groups. Providers caring for high-risk populations may not be fully aware of GC risk factors and may underestimate the potential for selective screening. Our aim was...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl17091
更新日期:2018-01-15 00:00:00
abstract:Background/Aims:Microvascular invasion (MVI) is an established risk factor for hepatocellular carcinoma (HCC). However, prediction models that specifically focus on the individual prognoses of HCC patients with MVI is lacking. Methods:A total of 385 HCC patients with MVI were randomly assigned to training and validati...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl18489
更新日期:2019-11-15 00:00:00
abstract::Cholangiocarcinoma is a catastrophic tumor with a high mortality rate, for which surgery is the most reliable treatment. However, these tumors progress insidiously and are difficult to diagnose early. Most patients lack the opportunity to receive surgery due to the advanced disease stage at the time of the diagnosis, ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2010.4.1.103
更新日期:2010-03-01 00:00:00
abstract:Background/Aims:The presence of invasion is a diagnostic criterion of early gastric cancer (EGC) in Korea, whereas diagnosis in Japan is based on enlarged nuclei and prominent nucleoli. Moreover, the depth of invasion is the location of cancer cell infiltration in Korea, whereas it is the location of lymphovascular inv...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl16281
更新日期:2017-05-15 00:00:00
abstract::It is known that neutropenia caused by combination pegylated interferon plus ribavirin therapy for hepatitis C virus (HCV) infection is well tolerated and carries a negligible risk of infection. Neutropenic enterocolitis is encountered most frequently in patients with hemato-oncologic diseases who are undergoing inten...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2009.3.3.218
更新日期:2009-09-01 00:00:00
abstract::A systematic review (SR) provides the best and most objective analysis of the existing evidence in a particular field. SRs and derived conclusions are essential for evidence-based strategies in medicine and evidence-based guidelines in clinical practice. The popularity of SRs has also increased markedly in the field o...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl14451
更新日期:2015-11-23 00:00:00
abstract::Most colonic lipomas are asymptomatic and need no treatment, whereas lesions larger than 2 cm can cause acute abdominal pain, changes in bowel habits, gastrointestinal bleeding, intussusception or bowel obstruction. Autoamputation of polypoid lesions in the gastrointestinal tract is indeed a rare phenomenon, and its p...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2011.5.3.380
更新日期:2011-09-01 00:00:00
abstract:Background/Aims:Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA; EUS-FNA) allows for diagnostic tissue specimens from various regions to be analyzed. However, diagnosing recurrent pancreaticobiliary cancer after surgery is sometimes difficult. We evaluated the efficacy of EUS-FNA in the diagnosis of loca...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl19200
更新日期:2020-09-15 00:00:00
abstract::Portal vein thrombosis (PVT) is commonly associated with liver cirrhosis, irrespective of the presence of hepatocellular carcinoma (HCC). Given that malignant PVT is a poor prognostic factor in patients with HCC, it is important to differentiate malignant PVT from benign PVT. Because malignant PVT has been reported to...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.1.116
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIMS:Signal transducers and activators of transcription (STATs) are a family of transcription factors that are activated in response to cytokines and growth factors. STAT3 activation has been implicated in modulating the activity of downstream mediators, such as Bcl-xL and matrix metalloproteinase-2 (MMP-2)....
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2012.6.1.45
更新日期:2012-01-01 00:00:00
abstract:Background/Aims:The validity of 13C-urea breath test (13C-UBT) for Helicobacter pylori detection is influenced by atrophic gastritis. The aim of this study was to evaluate the effect of citric acid on the accuracy of 13C-Urea breath test after H. pylori eradication therapy in a region where atrophic gastritis is common...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl18398
更新日期:2019-09-15 00:00:00
abstract:BACKGROUND/AIMS:Bacteremia following endoscopic retrograde cholangiopancreatography (ERCP) is a severe complication, but the risk factors for this condition have not yet been clearly determined. Thus, the aim of this study was to investigate the risk factors of post-ERCP bacteremia. METHODS:Among patients who underwen...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.2.228
更新日期:2013-03-01 00:00:00
abstract::Biliary obstructions are rarely caused by a foreign body and have received sparse attention. We present an unusual case with pruritis and abdominal pain caused by impacted full length surgical gauze within the common bile duct. The patient had previously undergone an open cholecystectomy. Radiological investigations w...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2011.5.2.245
更新日期:2011-06-01 00:00:00
abstract::The International Study Group for Pancreatic Fistula (ISGPF) made the first attempt to standardize the outcome measure of fistulas in the field of pancreatic surgery by publishing the definition and classification of postoperative pancreatic fistulas (POPFs) in 2005. POPFs were determined by any measurable volume of f...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl18229
更新日期:2019-03-15 00:00:00
abstract:BACKGROUND/AIMS:α-Fetoprotein (AFP) is the biomarker most widely used to detect hepatocellular carcinoma (HCC), despite its suboptimal diagnostic accuracy. Glypican-3 (GPC3) and osteopontin (OPN) are secreted glycoproteins that are reportedly associated with tumorigenesis and metastasis. This study was conducted to eva...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2014.8.2.177
更新日期:2014-03-01 00:00:00
abstract:Background/Aims:Gallstone disease (GSD) is a common gastrointestinal disorder. Clinical epidemiological studies revealed that alcohol consumption has a preventive effect on the development of GSD. This study aimed to evaluate the relative risks of drinking for GSD development and investigate the dose-response relations...
journal_title:Gut and liver
pub_type: 杂志文章,meta分析
doi:10.5009/gnl18278
更新日期:2019-01-15 00:00:00
abstract:Background/Aims:Knowledge regarding the quality metrics of fecal immunochemical test (FIT)-based colorectal cancer screening programs is limited. The aim of this study was to investigate the performance and quality metrics of a FIT-based screening program. Methods:In our screening program, asymptomatic subjects aged ≥...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl17030
更新日期:2018-03-15 00:00:00
abstract:BACKGROUND/AIMS:Recent data from Western populations have suggested that patients with sporadic duodenal adenomas are at a higher risk for the development of colorectal neoplasia. In this study, we compared the frequency of colorectal neoplasia in patients with sporadic duodenal adenomas to healthy control subjects. M...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2011.5.4.432
更新日期:2011-12-01 00:00:00
abstract::The use of self-expanding metallic stents in the upper gastrointestinal tract, placed under radiologic imaging or endoscopic guidance, is the current treatment of choice for the palliation of malignant gastrointestinal outlet obstructions. Advances in metallic stent design and delivery systems have progressed to the s...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2010.4.S1.S19
更新日期:2010-09-01 00:00:00
abstract::A 32-year-old man presented with epigastric pain. He had a previous episode of acute pancreatitis of undetermined cause 2 years earlier. The patient had taken trimethoprim (80 mg) and sulfamethoxazole (400 mg) twice daily because of acute urethritis 3 days prior to admission. No definite cause of acute pancreatitis co...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2010.4.2.250
更新日期:2010-06-01 00:00:00
abstract::During the past few decades, liver transplant has developed from a high-mortality procedure to an almost routine procedure with good survival outcomes. The development of living donor liver transplant has increased the availability of liver grafts, and the scope of indications for liver transplant has been expanding e...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl19265
更新日期:2021-01-15 00:00:00
abstract::This review article describes morphological aspects, gene abnormalities, and mucin expression profiles in precursor lesions such as pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN) of the pancreas, as well as their relation to pancreatic d...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2008.2.3.137
更新日期:2008-12-01 00:00:00
abstract:Background/Aims:Differentially diagnosing focal-type autoimmune pancreatitis (f-AIP) and pancreatic cancer (PC) is challenging. Contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) may provide information for differentiating pancreatic masses. In this study, we evaluated the usefulness of CEH-EUS in differentiati...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl17391
更新日期:2018-09-15 00:00:00
abstract:BACKGROUND/AIMS:Endoscopic sphincterotomy may be limited in Billroth II gastrectomy because of difficulty in orientating the duodenoscope and sphincterotome as a result of altered anatomy. This study was planned to investigate the efficacy and safety of endoscopic transpapillary large balloon dilation (EPBD) without pr...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2012.6.1.113
更新日期:2012-01-01 00:00:00
abstract::Liver transplantation has become a lifesaving procedure for patients who have chronic end-stage liver disease and acute liver failure. The satisfactory outcome of liver transplantation has led to insufficient supplies of deceased donor organs, particularly in East Asia. Hence, East Asian surgeons are concentrating on ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2009.3.3.145
更新日期:2009-09-01 00:00:00
abstract:Background/Aims:The hepatic steatosis index (HSI) is a noninvasive method to assess the severity of hepatic steatosis. Antiviral therapy (AVT) can impact aspartate aminotransferase and alanine aminotransferase levels, which are the main components of the HSI. Thus, we investigated the accuracy of the HSI in detecting h...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl19301
更新日期:2021-01-15 00:00:00