Abstract:
:Liver transplantation has become a lifesaving procedure for patients who have chronic end-stage liver disease and acute liver failure. The satisfactory outcome of liver transplantation has led to insufficient supplies of deceased donor organs, particularly in East Asia. Hence, East Asian surgeons are concentrating on developing and performing living-donor liver transplantation (LDLT). This review article describes an update on the present status of liver transplantation, mainly in adults, and highlights some recent developments on indications for transplantation, patient selection, donor and recipient operation between LDLT and deceased-donor liver transplantation (DDLT), immunosuppression, and long-term management of liver transplant recipients. Currently, the same indication criteria that exist for DDLT are applied to LDLT, with technical refinements for LDLT. In highly experienced centers, LDLT for high-scoring (>30 points) Model of End-Stage Liver Disease (MELD) patients and acute-on-chronic liver-failure patients yields comparably good outcomes to DDLT, because timely liver transplantation with good-quality grafting is possible. With increasing numbers of liver transplantations and long-term survivors, specialized attention should be paid to complications that develop in the long term, such as chronic renal failure, hypertension, diabetes mellitus, dyslipidemia, obesity, bone or neurological complications, and development of de novo tumors, which are highly related to the immunosuppressive treatment.
journal_name
Gut Liverjournal_title
Gut and liverauthors
Moon DB,Lee SGdoi
10.5009/gnl.2009.3.3.145subject
Has Abstractpub_date
2009-09-01 00:00:00pages
145-65issue
3eissn
1976-2283issn
2005-1212journal_volume
3pub_type
杂志文章相关文献
Gut and Liver文献大全abstract::The advent of biologics and biologic therapy has transformed the management of inflammatory bowel disease (IBD) with enhanced early and adequate responses to treatment, fewer hospitalizations, a reduced need for surgery, and unprecedented outcomes including complete mucosal and histologic healing. However, an importan...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl19209
更新日期:2020-11-15 00:00:00
abstract:BACKGROUND/AIMS:Halitosis is a symptom that bothers patients more socially than medically and its pathogenic mechanisms are unclear and treatment armamenterium is limited. Clinicians generally ignored active interventions. Since halitosis is closely associated with volatile sulfur compounds (VSCs), we used a Halimeter ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2008.2.2.113
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND/AIMS:To prospectively evaluate our palliative management of unresectable cholangiocarcinoma (CC) treated with tailored multimodal oncological therapy. METHODS:Between January 2005 and January 2010, 50 consecutive patients with unresectable CC and jaundice were palliated with percutaneous drainage. Forty-thr...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2010.4.S1.S82
更新日期:2010-09-01 00:00:00
abstract::Cap polyposis is a rare disorder with characteristic endoscopic and histological features; its etiology is still unknown, and no specific treatment has been established. We report a case of cap polyposis that improved remarkably after infliximab infusion and had no recurrence for 3 years. ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2009.3.4.325
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND/AIMS:Bacteremia following endoscopic retrograde cholangiopancreatography (ERCP) is a severe complication, but the risk factors for this condition have not yet been clearly determined. Thus, the aim of this study was to investigate the risk factors of post-ERCP bacteremia. METHODS:Among patients who underwen...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.2.228
更新日期:2013-03-01 00:00:00
abstract::Colonic diverticula are common whereas but rectal diverticula are very rare, with only sporadic reports in the literature since 1911. Most patients with rectal diverticula are diagnosed incidentally, inflammatory processes may have developed at the time of the diagnosis. We report the case of a 42-year-old woman prese...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2010.4.3.394
更新日期:2010-09-01 00:00:00
abstract::The guideline for the management of hepatocellular carcinoma (HCC) was first developed in 2003 and revised in 2009 by the Korean Liver Cancer Study Group and the National Cancer Center, Korea. Since then, many studies on HCC have been carried out in Korea and other countries. In particular, a substantial body of knowl...
journal_title:Gut and liver
pub_type: 杂志文章,实务指引
doi:10.5009/gnl14460
更新日期:2015-05-23 00:00:00
abstract:Background/Aims:This study aimed to elucidate the epidemiological and clinical characteristics of chronic hepatitis C (CHC) patients in South Korea from 2007 to 2017 and to compare the treatment patterns between two periods before and after the first approval of direct-acting antivirals (DAA) in South Korea in 2015. M...
journal_title:Gut and liver
pub_type: 杂志文章,多中心研究
doi:10.5009/gnl19005
更新日期:2020-03-15 00:00:00
abstract::During the past few decades, liver transplant has developed from a high-mortality procedure to an almost routine procedure with good survival outcomes. The development of living donor liver transplant has increased the availability of liver grafts, and the scope of indications for liver transplant has been expanding e...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl19265
更新日期:2021-01-15 00:00:00
abstract:Background/Aims:Microvascular invasion (MVI) is an established risk factor for hepatocellular carcinoma (HCC). However, prediction models that specifically focus on the individual prognoses of HCC patients with MVI is lacking. Methods:A total of 385 HCC patients with MVI were randomly assigned to training and validati...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl18489
更新日期:2019-11-15 00:00:00
abstract::Cell death is now reclassified into several types based on the mechanisms and morphologic phenotype. Understanding of such classifications offers insights into the pathogenesis of liver disease, as well as diagnostic or therapeutic implications. Apoptosis is recognized relatively easily due to its unique morphology, b...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl18486
更新日期:2020-01-15 00:00:00
abstract:Background/Aims:Electrohydraulic lithotripsy (EHL) under endoscopic retrograde cholangiopancreatography (ERCP) guidance can be an option to treat difficult stones. Recently, a digital, single-operator cholangioscope (SPY-DS) has become available. Peroral transluminal cholangioscopy (PTLC) using SPY-DS has also been rep...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl17352
更新日期:2018-07-15 00:00:00
abstract:Background/Aims:Knowledge regarding the quality metrics of fecal immunochemical test (FIT)-based colorectal cancer screening programs is limited. The aim of this study was to investigate the performance and quality metrics of a FIT-based screening program. Methods:In our screening program, asymptomatic subjects aged ≥...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl17030
更新日期:2018-03-15 00:00:00
abstract:BACKGROUND/AIMS:The quality of bowel preparation (QBP) is the important factor in performing a successful colonoscopy. Several factors influencing QBP have been reported; however, some factors, such as the optimal preparation-to-colonoscopy time interval, remain controversial. This study aimed to determine the factors ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl13228
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND/AIMS:The primary pathophysiologic abnormality in achalasia is known to be a loss of inhibitory myenteric ganglion cells, which may result from an immune-mediated response or neuronal degeneration. The aim of this study was to identify proteins suggestive of an immune-mediated response or neuronal degeneratio...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.4.411
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND/AIMS:Endoscopic submucosal dissection (ESD), a new and potentially curative method for treating gastrointestinal neoplasms, may have longer procedure time and the risk of complications when compared to conventional endoscopic mucosal resection. This study evaluated the efficacy and safety of ESD in patients ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2010.4.2.186
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND/AIMS:Several precut techniques have been used to gain biliary access for difficult cases. The aim of this study was to evaluate the success and complication rates of two precut techniques, transpancreatic septotomy (TPS) and needle knife infundibulotomy (NKI), in difficult biliary cannulation due to the pres...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl14223
更新日期:2015-07-01 00:00:00
abstract:Background/Aims:The present study aimed to evaluate the safety and efficacy of simeprevir-based triple therapy with reduced doses of pegylated interferon (PEG-IFN) and ribavirin for interferon (IFN) ineligible patients, such as elderly and/or cirrhotic patients, and to elucidate the factors contributing to a sustained ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl16525
更新日期:2017-07-15 00:00:00
abstract:BACKGROUND/AIMS:To investigate the association between the baseline profiles and dynamics of hepatitis B virus (HBV) DNA polymerase gene mutations and the long-term virological response of lamivudine (LAM)-adefovir (ADV) combination therapy in patients with LAM-resistant chronic hepatitis B. METHODS:Seventy-five patie...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl14018
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND/AIMS:The aim of this study was to evaluate the usefulness of health screening for early detection and improved prognosis in pancreatic cancer. METHODS:Between 1995 and 2008, 176,361 examinees visited the Health Promotion Center (HPC). Twenty patients diagnosed with pancreatic cancer were enrolled. During th...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2011.5.2.194
更新日期:2011-06-01 00:00:00
abstract:Background/Aims:Although forceps biopsy is performed for suspicious gastric tumors during endoscopy, it is difficult to determine treatment strategies for atypical gastric glands due to uncertainty of the diagnosis. The aim of this study was to investigate clinical implications and risk factors for predicting malignanc...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl18006
更新日期:2018-09-15 00:00:00
abstract:BACKGROUND/AIMS:We aimed to assess the effectiveness of self-expanding metal stent (SEMS) insertion by evaluating the learning curve in relation to the experience of an endoscopist. METHODS:We retrospectively analyzed the outcomes of 120 SEMS insertion procedures performed by one endoscopist in patients with malignant...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2012.6.3.328
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND/AIMS:Second-look endoscopy is performed to check for the possibility of post-endoscopic submucosal dissection (ESD) bleeding and to perform prophylactic hemostasis in most hospitals; however, there is little evidence about the efficacy of second-look endoscopy. We investigated whether second-look endoscopy a...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl13422
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND/AIMS:We aimed to investigate the relation-ships among various mutations of the p53 gene and their protein products, histological characteristics, and disease prognosis of primary colorectal cancer in Isfahan, central Iran. METHODS:Sixty-one patients with colorectal adenocarcinoma were enrolled in the study....
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.3.295
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND/AIMS:Left-sided diverticulitis is increasing in Japan, and many studies report that left-sided diverticulitis is more likely to be severe. Therefore, it is important to identify the features and risk factors for left-sided diverticulitis. We hypothesized that left-sided diverticulitis in Japan is related to ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.5.532
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND/AIMS:Endoscopic sphincterotomy may be limited in Billroth II gastrectomy because of difficulty in orientating the duodenoscope and sphincterotome as a result of altered anatomy. This study was planned to investigate the efficacy and safety of endoscopic transpapillary large balloon dilation (EPBD) without pr...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2012.6.1.113
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIMS:The presence of Helicobacter pylori (H. pylori) infection represents a high-risk state of gastric cancer, but the risk is even higher in gastric atrophy. H. pylori stool antigen (HpSA) and serum pepsinogen (PG) tests are useful tools for screening present infection and gastric atrophy, respectively. To ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2009.3.2.95
更新日期:2009-06-01 00:00:00
abstract::Cholangiocytes, the lining epithelial cells in bile ducts, are an important subset of liver cells. They are activated by endogenous and exogenous stimuli and are involved in the modification of bile volume and composition. They are also involved in damaging and repairing the liver. Cholangiocytes have many functions i...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl16033
更新日期:2016-09-15 00:00:00
abstract:BACKGROUND/AIMS:Despite the potent suppression of the hepatitis B virus with modern antiviral agents, only a minority of HBeAg-positive patients achieve hepatitis B e antigen seroconversion. We aimed to explore the potential efficacy of combination therapy consisting of pegylated interferon (p-IFN) and an oral antivira...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl14256
更新日期:2016-07-16 00:00:00
abstract:BACKGROUND/AIMS:High intensity focused ultrasound (HIFU) utilizes a targeted extracorporeal focused ultrasound beam to ablate neoplastic pancreatic tissue. We used an in vitro model to examine the effects of bone, metallic stents, plastic stents, metal plates, and cyst-like lesions on HIFU treatment. METHODS:HIFU was ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2014.8.4.433
更新日期:2014-07-01 00:00:00