Concurrent chemoradiation in a patient with unresectable cholangiocarcinoma.

Abstract:

:Cholangiocarcinoma is a catastrophic tumor with a high mortality rate, for which surgery is the most reliable treatment. However, these tumors progress insidiously and are difficult to diagnose early. Most patients lack the opportunity to receive surgery due to the advanced disease stage at the time of the diagnosis, at which point only few alternative treatments are available. There is a need for more effective therapy to improve the survival or quality of life of these patients. The present case was a 73-year-old male who presented with jaundice and fatigue underwent CT imaging, in which a 3.5x4.0-cm low-attenuation mass was found in hepatic segment 4. Cholangiocarcinoma was diagnosed by cytological examination of the bile juice. A combination of CyberKnife radiosurgery and S-1 oral chemotherapy was performed. The patient was alive at a 8-month follow-up, and serial CT scans revealed a markedly regressed tumor. Therefore, we suggest that concurrent chemoradiation with the CyberKnife and S-1 is a treatment option for advanced cholangiocarcinoma.

journal_name

Gut Liver

journal_title

Gut and liver

authors

Park JS,Lee DH,Jeong S,Kim WC,Lee JI,Lee SY,Park SD,Nha SY

doi

10.5009/gnl.2010.4.1.103

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

103-5

issue

1

eissn

1976-2283

issn

2005-1212

journal_volume

4

pub_type

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