Abstract:
Background/Aims:The validity of 13C-urea breath test (13C-UBT) for Helicobacter pylori detection is influenced by atrophic gastritis. The aim of this study was to evaluate the effect of citric acid on the accuracy of 13C-Urea breath test after H. pylori eradication therapy in a region where atrophic gastritis is common. Methods:In this prospective study, H. pylori-positive patients received 13C-UBT after H. pylori eradication regimen. They were classified into citric acid group and control group. To determine diagnostic accuracy of 13C-UBT, patients were offered invasive methods. Results:A total of 1,207 who successfully took H. pylori-eradication regimen received UBT. They were assigned into the citric acid group (n=562) and the control group (n=645). The mean 13C-UBT value of the citric acid group was 10.3±26.4‰, which was significantly (p<0.001) higher than that of that control group (5.1‰±12.6‰). Of these patients 122 patients were evaluated by endoscopic biopsy methods. Based on invasive tests, the accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of 13C-UBT for the citric acid group were 83.3%, 91.7%, 81.3%, 55.0%, and 97.5%, respectively. Those of the control group were 87.7%, 90.9%, 88.2%, 62.5%, and 97.8%, respectively. They were not significantly different between the two groups. Although the presence of gastric atrophy and intestinal metaplasia (IM) decreased the accuracy, the decrease was not significant. Conclusions:In a country with high prevalence of atrophic gastritis or IM, false positivity remained common despite the use of citric acid in 13C-UBT.
journal_name
Gut Liverjournal_title
Gut and liverauthors
Kwon YH,Kim N,Yoon H,Shin CM,Park YS,Lee DHdoi
10.5009/gnl18398subject
Has Abstractpub_date
2019-09-15 00:00:00pages
506-514issue
5eissn
1976-2283issn
2005-1212pii
gnl18398journal_volume
13pub_type
杂志文章相关文献
Gut and Liver文献大全abstract:BACKGROUND/AIMS:Knowledge of the risk factors associated with adverse outcomes after percutaneous endoscopic gastrostomy (PEG) may be helpful for developing PEG recommendations. The purpose of this study was to identify the clinical risk factors associated with adverse clinical outcomes after PEG, especially regarding ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2014.8.3.248
更新日期:2014-05-01 00:00:00
abstract::The guideline for the management of hepatocellular carcinoma (HCC) was first developed in 2003 and revised in 2009 by the Korean Liver Cancer Study Group and the National Cancer Center, Korea. Since then, many studies on HCC have been carried out in Korea and other countries. In particular, a substantial body of knowl...
journal_title:Gut and liver
pub_type: 杂志文章,实务指引
doi:10.5009/gnl14460
更新日期:2015-05-23 00:00:00
abstract:BACKGROUND/AIMS:To investigate the association between the baseline profiles and dynamics of hepatitis B virus (HBV) DNA polymerase gene mutations and the long-term virological response of lamivudine (LAM)-adefovir (ADV) combination therapy in patients with LAM-resistant chronic hepatitis B. METHODS:Seventy-five patie...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl14018
更新日期:2015-01-01 00:00:00
abstract:Background/Aims:Although many studies have reported the promising effect of neoadjuvant treatment for borderline resectable pancreatic cancer (BRPC) to increase resectability, only a few studies have recommended the use of firstline chemotherapeutic agents as neoadjuvant treatment for BRPC. The current study compared c...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl20070
更新日期:2020-08-26 00:00:00
abstract:BACKGROUND/AIMS:Patients with cholangiocarcinoma usually present at an advanced stage, and more than 50% of cases are not resectable at the time of diagnosis. Recently, photodynamic therapy (PDT) has been proposed as a palliative and neoadjuvant modality. We evaluated whether combination of PDT and chemotherapy is more...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2014.8.3.318
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND/AIMS:The aim of this study was to evaluate the usefulness of health screening for early detection and improved prognosis in pancreatic cancer. METHODS:Between 1995 and 2008, 176,361 examinees visited the Health Promotion Center (HPC). Twenty patients diagnosed with pancreatic cancer were enrolled. During th...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2011.5.2.194
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND/AIMS:Although laparoscopic fundoplication is a well-established therapy for gastroesophageal reflux disease (GERD) in Western countries, the mainstay of GERD treatment in Korea is long-term proton pump inhibitor (PPI) use. The aim of the present study was to evaluate nationwide data regarding antireflux surg...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl15406
更新日期:2016-09-15 00:00:00
abstract:Background/Aims:The presence of invasion is a diagnostic criterion of early gastric cancer (EGC) in Korea, whereas diagnosis in Japan is based on enlarged nuclei and prominent nucleoli. Moreover, the depth of invasion is the location of cancer cell infiltration in Korea, whereas it is the location of lymphovascular inv...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl16281
更新日期:2017-05-15 00:00:00
abstract::Gastroparesis (Gp) is a chronic disease that presents with clinical symptoms of early satiety, bloating, nausea, vomiting, and abdominal pain. Along with these symptoms, an objective finding of delayed gastric emptying, along with a documented absence of gastric outlet obstruction, are required for diagnosis. This art...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl16336
更新日期:2017-09-15 00:00:00
abstract:BACKGROUND/AIMS:The quality of bowel preparation (QBP) is the important factor in performing a successful colonoscopy. Several factors influencing QBP have been reported; however, some factors, such as the optimal preparation-to-colonoscopy time interval, remain controversial. This study aimed to determine the factors ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl13228
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND/AIMS:Astaxanthin is a carotenoid pigment that has antioxidant, antitumoral, and anti-inflammatory properties. In this in vitro study, we investigated the mechanism of anticancer effects of astaxanthin in gastric carcinoma cell lines. METHODS:The human gastric adenocarcinoma cell lines AGS, KATO-III, MKN-45,...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl15208
更新日期:2016-05-23 00:00:00
abstract::It is known that neutropenia caused by combination pegylated interferon plus ribavirin therapy for hepatitis C virus (HCV) infection is well tolerated and carries a negligible risk of infection. Neutropenic enterocolitis is encountered most frequently in patients with hemato-oncologic diseases who are undergoing inten...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2009.3.3.218
更新日期:2009-09-01 00:00:00
abstract::Esophageal intramural pseudodiverticulosis (EIP) is a rare benign disease that is characterized by multiple tiny flask-shaped outpouching lesions of the esophageal wall. The etiology is unknown, but the pathologic findings include dilatation of excretory ducts of submucosal glands. The predominant symptom is dysphagia...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2011.5.1.93
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND/AIMS:Sacroiliitis (SI) is one of the most frequent extraintestinal manifestations in inflammatory bowel disease (IBD) patients, but the exact prevalence has not been evaluated in Asia. There are few data on the association between SI and other clinical features of IBD. The prevalence of SI was evaluated usin...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2010.4.3.338
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND/AIMS:The notion that acute hepatitis A superimposed on chronic hepatitis B infection leads to a worse outcome than acute hepatitis A alone remains controversial. The aim of this study was to determine the influence of the presence of hepatitis B surface antigen (HBsAg) on the severity of acute hepatitis A. ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2011.5.4.500
更新日期:2011-12-01 00:00:00
abstract:Background/Aims:Information regarding the efficacy of early infliximab treatment in pediatric patients with Crohn's disease (CD) is limited. We aimed to evaluate the impact of early combined immunosuppression on linear growth in pediatric patients with CD by performing step-up comparisons. Methods:This retrospective s...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl17290
更新日期:2018-05-15 00:00:00
abstract:BACKGROUND/AIMS:M2 pyruvate kinase (M2-PK) is an enzyme that is produced in undifferentiated and proliferating tissues. This study aims to evaluate the usefulness of the immunochromatographic M2 pyruvate kinase (iM2-PK) for the screening of colorectal cancer (CRC) and premalignant lesions. METHODS:Healthy volunteers a...
journal_title:Gut and liver
pub_type: 杂志文章,多中心研究
doi:10.5009/gnl13457
更新日期:2015-09-23 00:00:00
abstract::Cap polyposis is a rare disorder with characteristic endoscopic and histological features; its etiology is still unknown, and no specific treatment has been established. We report a case of cap polyposis that improved remarkably after infliximab infusion and had no recurrence for 3 years. ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2009.3.4.325
更新日期:2009-12-01 00:00:00
abstract::Biliary obstructions are rarely caused by a foreign body and have received sparse attention. We present an unusual case with pruritis and abdominal pain caused by impacted full length surgical gauze within the common bile duct. The patient had previously undergone an open cholecystectomy. Radiological investigations w...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2011.5.2.245
更新日期:2011-06-01 00:00:00
abstract:Background/Aims:Knowledge regarding the quality metrics of fecal immunochemical test (FIT)-based colorectal cancer screening programs is limited. The aim of this study was to investigate the performance and quality metrics of a FIT-based screening program. Methods:In our screening program, asymptomatic subjects aged ≥...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl17030
更新日期:2018-03-15 00:00:00
abstract:BACKGROUND/AIMS:Although normal endoscopic findings are, as a rule, part of the diagnosis of microscopic colitis, sev-eral cases of macroscopic lesions (MLs) have been reported in collagenous colitis, but hardly in lymphocytic colitis (LC). The aim of this study was to investigate the endoscopic, clini-cal, and histopa...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl13373
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND/AIMS:In patients with corticosteroid-refractory ulcerative colitis (UC), cyclosporine or infliximab may be added to the treatment regimen to induce remission. Here, we aimed to compare the efficacy of cyclosporine and infliximab. METHODS:Between January 1995 and May 2012, the medical records of 43 patients ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl14120
更新日期:2015-09-23 00:00:00
abstract:Background/Aims:Delayed bleeding after gastric endoscopic submucosal dissection (ESD) commonly occurs within 3 days, but it may also occur after 1 week following ESD, especially in antiplatelet agent users. We evaluated the risk of delayed bleeding in post-ESD ulcers using the Forrest classification. Methods:Registry ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl16232
更新日期:2017-07-15 00:00:00
abstract:BACKGROUND/AIMS:There has been a lack of research comparing balloon dilatation and self-expandable metal stent (SEMS) placement to determine which is better for long-term clinical outcomes in patients with benign colorectal strictures. We aimed to compare the clinical efficacy and complication rates of balloon dilatati...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl13326
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND/AIMS:Aging gastric mucosa is known to have decreased mucosal defenses and increased susceptibility to injury by nonsteroidal anti-inflammatory drugs. Depending on the type of nonsteroidal anti-inflammatory drug (NSAID), the underlying mechanisms and the extent of damage to the stomach or intestine may differ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2012.6.2.210
更新日期:2012-04-01 00:00:00
abstract:Background/Aims:We recently identified recessive mutations in the solute carrier organic anion transporter family member 2A1 gene (SLCO2A1) as causative variants of chronic nonspecific multiple ulcers of the small intestine (chronic enteropathy associated with SLCO2A1, CEAS). The aim of this study was to investigate th...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl18261
更新日期:2019-01-15 00:00:00
abstract::Metastasis to the stomach from renal cell carcinoma (RCC) is extremely rare. Usually, gastric metastasis seems to be a late event in patients with RCC and is accompanied by disseminated tumor spread to other organs. Solitary synchronous gastric metastasis from small, localized RCC has rarely been reported. We report a...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2012.6.3.388
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND/AIMS:Bacteremia following endoscopic retrograde cholangiopancreatography (ERCP) is a severe complication, but the risk factors for this condition have not yet been clearly determined. Thus, the aim of this study was to investigate the risk factors of post-ERCP bacteremia. METHODS:Among patients who underwen...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.2.228
更新日期:2013-03-01 00:00:00
abstract::A systematic review (SR) provides the best and most objective analysis of the existing evidence in a particular field. SRs and derived conclusions are essential for evidence-based strategies in medicine and evidence-based guidelines in clinical practice. The popularity of SRs has also increased markedly in the field o...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl14451
更新日期:2015-11-23 00:00:00
abstract:BACKGROUND/AIMS:Drug-induced liver injury (DILI) is a frequent cause of pediatric liver disease; however, the data on DILI are remarkably limited. METHODS:All 69 children hospitalized with DILI between January 2009 and December 2011 were retrospectively studied. RESULTS:A total of 37.7% of the children had medical hi...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl14184
更新日期:2015-07-01 00:00:00