Simeprevir-Based Triple Therapy with Reduced Doses of Pegylated Interferon α-2a Plus Ribavirin for Interferon Ineligible Patients with Genotype 1b Hepatitis C Virus.

abstract：:The advent of biologics and biologic therapy has transformed the management of inflammatory bowel disease (IBD) with enhanced early and adequate responses to treatment, fewer hospitalizations, a reduced need for surgery, and unprecedented outcomes including complete mucosal and histologic healing. However, an importan...

journal_title：Gut and liver

authors： Banerjee R,Ali RAR,Wei SC,Adsul S

更新日期：2020-11-15 00:00:00

abstract：:A 32-year-old man presented with epigastric pain. He had a previous episode of acute pancreatitis of undetermined cause 2 years earlier. The patient had taken trimethoprim (80 mg) and sulfamethoxazole (400 mg) twice daily because of acute urethritis 3 days prior to admission. No definite cause of acute pancreatitis co...

journal_title：Gut and liver

authors： Park TY,Oh HC,Do JH

更新日期：2010-06-01 00:00:00

abstract：:It is known that neutropenia caused by combination pegylated interferon plus ribavirin therapy for hepatitis C virus (HCV) infection is well tolerated and carries a negligible risk of infection. Neutropenic enterocolitis is encountered most frequently in patients with hemato-oncologic diseases who are undergoing inten...

journal_title：Gut and liver

authors： Kim JH,Jang JW,You CR,You SY,Jung MK,Jung JH

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND/AIMS:Cytapheresis (CAP) is a novel strategy for ulcerative colitis (UC). However, there is insufficient data on the long-term outcome of UC patients who achieve remission by CAP. This study involved patients with severe UC who refracted to intravenous (iv) corticosteroid. METHODS:Forty-seven UC patients who...

journal_title：Gut and liver

authors： Fukunaga K,Nagase K,Kusaka T,Hida N,Ohda Y,Yoshida K,Tozawa K,Kamikozuru K,Iimuro M,Nakamura S,Miwa H,Matsumoto T

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND/AIMS:As the incidence rate of and mortality from pseudomembranous colitis (PMC) are increasing worldwide, it is important to study the simple predictive risk factors for PMC among patients with hospital-acquired diarrhea (HAD). This study focused on identifying the clinical risk factors that can easily predi...

journal_title：Gut and liver

authors： Yang BK,Do BJ,Kim EJ,Lee JU,Kim MH,Kang JG,Kim HS,Kim KH,Jang MK,Lee JH,Kim HY,Shin WG

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Ischemic colitis includes a wide clinical spectrum ranging from mild to severe forms. This study aimed to determine the factors that are related to the occurrence of severe ischemic colitis. METHODS:This multicenter study was conducted retrospectively in Korea. The patients were divided into mild and s...

journal_title：Gut and liver

authors： Choi SR,Jee SR,Song GA,Park SJ,Lee JH,Song CS,Park HU

更新日期：2015-11-23 00:00:00

abstract：Background/Aims:We recently identified recessive mutations in the solute carrier organic anion transporter family member 2A1 gene (SLCO2A1) as causative variants of chronic nonspecific multiple ulcers of the small intestine (chronic enteropathy associated with SLCO2A1, CEAS). The aim of this study was to investigate th...

journal_title：Gut and liver

authors： Yanai S,Yamaguchi S,Nakamura S,Kawasaki K,Toya Y,Yamada N,Eizuka M,Uesugi N,Umeno J,Esaki M,Okimoto E,Ishihara S,Sugai T,Matsumoto T

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND/AIMS:Although gastric hyperplastic polyps are usually considered as benign lesions, a low risk of carcinomatous conversion is currently recognized. We aimed to identify the characteristics of hyperplastic polyps undergoing neoplastic transformation. METHODS:A total of 269 gastric hyperplastic polyps from 21...

journal_title：Gut and liver

authors： Han AR,Sung CO,Kim KM,Park CK,Min BH,Lee JH,Kim JY,Chang DK,Kim YH,Rhee PL,Rhee JC,Kim JJ

更新日期：2009-12-01 00:00:00

abstract：:Portal hypertension is a major pathophysiology in patients with cirrhosis. Portal pressure is the gold standard to evaluate the severity of portal hypertension, and radiological intervention is the only procedure for pressure measurement. Ultrasound (US) is a simple and noninvasive imaging modality available worldwide...

journal_title：Gut and liver

authors： Maruyama H,Yokosuka O

更新日期：2017-07-15 00:00:00

abstract：:Most colonic lipomas are asymptomatic and need no treatment, whereas lesions larger than 2 cm can cause acute abdominal pain, changes in bowel habits, gastrointestinal bleeding, intussusception or bowel obstruction. Autoamputation of polypoid lesions in the gastrointestinal tract is indeed a rare phenomenon, and its p...

journal_title：Gut and liver

authors： Jeong HK,Cho SB,Seo TJ,Lee KR,Lee WS,Kim HS,Joo YE

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND/AIMS:Although laparoscopic fundoplication is a well-established therapy for gastroesophageal reflux disease (GERD) in Western countries, the mainstay of GERD treatment in Korea is long-term proton pump inhibitor (PPI) use. The aim of the present study was to evaluate nationwide data regarding antireflux surg...

journal_title：Gut and liver

authors： Lee JH,Park JM,Han SU,Kim JJ,Song KY,Ryu SW,Seo KW,Kim HI,Kim W,Korean Antireflux Surgery Study (KARS) Group.

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND/AIMS:The aim of this study was to evaluate the effect of the synthetic S-allyl-L-cysteine (SAC) PMK-S005 on gastric acid secretion, inflammation, and antioxidant enzymes in aging rats. METHODS:The rats were divided into four groups at 31 weeks of age and were continuously fed a diet containing a vehicle con...

journal_title：Gut and liver

authors： Choi YJ,Kim N,Lee JY,Nam RH,Suh JH,Lee SM,Ham MH,Jo HJ,Shim YK,Park YH,Lee JC,Choi YJ,Lee HS,Lee DH

更新日期：2016-09-15 00:00:00

abstract：:Functional dyspepsia (FD) is a common but under-recognized syndrome comprising bothersome recurrent postprandial fullness, early satiety, or epigastric pain/burning. Epidemiologically, there are two clinically distinct FD syndromes (although these often overlap clinically): postprandial distress syndrome (PDS; compris...

journal_title：Gut and liver

authors： Talley NJ

更新日期：2017-05-15 00:00:00

abstract：Background/Aims:Obesity is a risk factor for gastroesophageal reflux disease (GERD), with several studies demonstrating positive associations between body mass index (BMI) and GERD symptoms. However, little is known about the effect of BMI changes on erosive esophagitis (EE). In this study, we investigated whether BMI ...

journal_title：Gut and liver

authors： Bang KB,Park JH

更新日期：2018-11-15 00:00:00

abstract：:Whether Helicobacter pylori eradication actually reduces the risk of metachronous gastric cancer (MGC) development remains a controversial question. In this review, we addressed this topic by reviewing the results of clinical investigations and molecular pathological analyses of the roles of H. pylori eradication and ...

journal_title：Gut and liver

authors： Watari J,Tomita T,Tozawa K,Oshima T,Fukui H,Miwa H

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND/AIMS:Endoscopic sphincterotomy may be limited in Billroth II gastrectomy because of difficulty in orientating the duodenoscope and sphincterotome as a result of altered anatomy. This study was planned to investigate the efficacy and safety of endoscopic transpapillary large balloon dilation (EPBD) without pr...

journal_title：Gut and liver

authors： Lee TH,Hwang JC,Choi HJ,Moon JH,Cho YD,Yoo BM,Park SH,Kim JH,Kim SJ

更新日期：2012-01-01 00:00:00

abstract：:The use of self-expanding metallic stents in the upper gastrointestinal tract, placed under radiologic imaging or endoscopic guidance, is the current treatment of choice for the palliation of malignant gastrointestinal outlet obstructions. Advances in metallic stent design and delivery systems have progressed to the s...

journal_title：Gut and liver

authors： Kang SG

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND/AIMS:Signal transducers and activators of transcription (STATs) are a family of transcription factors that are activated in response to cytokines and growth factors. STAT3 activation has been implicated in modulating the activity of downstream mediators, such as Bcl-xL and matrix metalloproteinase-2 (MMP-2)....

journal_title：Gut and liver

authors： Lee SW,Ahn YY,Kim YS,Kang SB,Nam SW,Lee DS,Jeong HY,Kim JM

更新日期：2012-01-01 00:00:00

abstract：Background/Aims:Although many studies have reported the promising effect of neoadjuvant treatment for borderline resectable pancreatic cancer (BRPC) to increase resectability, only a few studies have recommended the use of firstline chemotherapeutic agents as neoadjuvant treatment for BRPC. The current study compared c...

journal_title：Gut and liver

authors： Choi YJ,Byun Y,Kang JS,Kim HS,Han Y,Kim H,Kwon W,Oh DY,Paik WH,Lee SH,Ryu JK,Kim YT,Lee K,Kim H,Chie EK,Jang JY

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND/AIMS:Bacteremia following endoscopic retrograde cholangiopancreatography (ERCP) is a severe complication, but the risk factors for this condition have not yet been clearly determined. Thus, the aim of this study was to investigate the risk factors of post-ERCP bacteremia. METHODS:Among patients who underwen...

journal_title：Gut and liver

authors： Kwak MS,Jang ES,Ryu JK,Kim YT,Yoon YB,Park JK

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND/AIMS:The role of Helicobacter pylori in gastric carcinogenesis is unclear, but H. pylori infection is thought to predispose carriers to gastric cancer. The aim of this study was to investigate the relationship between the extent of DNA damage in normal gastric epithelial cells and H. pylori-positive and -neg...

journal_title：Gut and liver

authors： Marie MA,Altahir IE

更新日期：2011-09-01 00:00:00

abstract：:Acute symptomatic portal vein obstruction related to biliary stenting is an extremely rare but life-threatening complication. This usually occurs in patients with either tumor invasion into the portal vein or pre-existing portal vein thrombus. Therefore, the portal vein should be carefully evaluated before placing a b...

journal_title：Gut and liver

authors： Woo KH,Kim JB,Chang YJ,Kim HJ,Baek IH,Ko JS,Woo JY,Kim HD,Lee MS

更新日期：2008-06-01 00:00:00

abstract：:We report herein three cases of inflammatory myoglandular polyp (IMGP) presenting as hematochezia. The polyps had pedunculated, red, and smooth features, and were 12, 12, and 15 mm in diameter and located in the sigmoid colon, transverse colon, and rectum, respectively. Endoscopic polypectomies were performed. Histolo...

journal_title：Gut and liver

authors： Chung SH,Son BK,Park YS,Jo YJ,Kim SH,Jun DW,Cheong ES,Lee WM,Ju JE

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND/AIMS:Standard treatments are not available for hilar nonresectable cholangiocarcinoma (NCC). It is unknown whether combination therapy of photodynamic therapy (PDT) plus systemic chemotherapy is superior to PDT alone. METHODS:We retrospectively reviewed 68 patients with hilar NCC treated with either PDT plu...

journal_title：Gut and liver

authors： Wentrup R,Winkelmann N,Mitroshkin A,Prager M,Voderholzer W,Schachschal G,Jürgensen C,Büning C

更新日期：2016-05-23 00:00:00

abstract：:Colonic diverticula are common whereas but rectal diverticula are very rare, with only sporadic reports in the literature since 1911. Most patients with rectal diverticula are diagnosed incidentally, inflammatory processes may have developed at the time of the diagnosis. We report the case of a 42-year-old woman prese...

journal_title：Gut and liver

authors： Jung SH,Kim JH

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND/AIMS:The pathophysiologic mechanism of rectal hyposensitivity (RH) is not well documented, and the significance of RH in biofeedback therapy (BFT) has not been evaluated. Thus, we aimed to assess the effect of BFT in constipated patients according to the presence of RH. METHODS:Five hundred and ninety const...

journal_title：Gut and liver

authors： Ahn JY,Myung SJ,Jung KW,Yang DH,Koo HS,Seo SY,Yoon IJ,Kim KJ,Ye BD,Byeon JS,Jung HY,Yang SK,Kim JH

更新日期：2013-03-01 00:00:00

abstract：Background/Aims:Although balloon-assisted enteroscopy (BAE) enables endoscopic visualization of small bowel (SB) involvement in Crohn's disease (CD), there is no data on the changes in outcomes over time. We therefore investigated the changes in BAE use on CD patients over different time periods in terms of its role an...

journal_title：Gut and liver

authors： Jeon SR,Kim JO,Byeon JS,Yang DH,Ko BM,Goong HJ,Jang HJ,Park SJ,Kim ER,Hong SN,Im JP,Kim SE,Koo JS,Eun CS,Chang DK,Korean Association for the Study of Intestinal Disease(KASID).

更新日期：2020-07-06 00:00:00

abstract：:During the past few decades, liver transplant has developed from a high-mortality procedure to an almost routine procedure with good survival outcomes. The development of living donor liver transplant has increased the availability of liver grafts, and the scope of indications for liver transplant has been expanding e...

journal_title：Gut and liver

authors： Chu KK,Wong KH,Chok KS

更新日期：2021-01-15 00:00:00

abstract：:This review article describes morphological aspects, gene abnormalities, and mucin expression profiles in precursor lesions such as pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN) of the pancreas, as well as their relation to pancreatic d...

journal_title：Gut and liver

authors： Yonezawa S,Higashi M,Yamada N,Goto M

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND/AIMS:Astaxanthin is a carotenoid pigment that has antioxidant, antitumoral, and anti-inflammatory properties. In this in vitro study, we investigated the mechanism of anticancer effects of astaxanthin in gastric carcinoma cell lines. METHODS:The human gastric adenocarcinoma cell lines AGS, KATO-III, MKN-45,...

journal_title：Gut and liver

authors： Kim JH,Park JJ,Lee BJ,Joo MK,Chun HJ,Lee SW,Bak YT

更新日期：2016-05-23 00:00:00