Abstract:
Background/Aims:Knowledge regarding the quality metrics of fecal immunochemical test (FIT)-based colorectal cancer screening programs is limited. The aim of this study was to investigate the performance and quality metrics of a FIT-based screening program. Methods:In our screening program, asymptomatic subjects aged ≥50 years underwent an annual FIT, and subjects with positive FIT results underwent a subsequent colonoscopy. The performance of the FIT and colonoscopy was analyzed in individuals with a positive FIT who completed the program between 2009 and 2015 at a university hospital. Results:Among the 51,439 screened participants, 75.1% completed the FIT. The positive rate was 1.1%, and the colonoscopy completion rate in these patients was 68.6%. The positive predictive values of cancer and advanced neoplasia were 5.5% and 19.1%, respectively. The adenoma detection rate in the patients who underwent colonoscopy after a positive FIT was 48.2% (60.0% for men and 33.6% for women). The group with the highest tertile quantitative FIT level showed a significantly higher detection rate of advanced neoplasia than the group with the lowest tertile (odds ratio, 2.6; 95% confidence interval, 1.4 to 5.1; p<0.001). Conclusions:The quality metrics used in the United States and Europe may be directly introduced to other countries, including Korea. However, the optimal quality metrics should be established in each country.
journal_name
Gut Liverjournal_title
Gut and liverauthors
Kim DH,Cha JM,Kwak MS,Yoon JY,Cho YH,Jeon JW,Shin HP,Joo KR,Lee JIdoi
10.5009/gnl17030subject
Has Abstractpub_date
2018-03-15 00:00:00pages
183-189issue
2eissn
1976-2283issn
2005-1212pii
gnl17030journal_volume
12pub_type
杂志文章相关文献
Gut and Liver文献大全abstract:Background/Aims:Delayed bleeding after gastric endoscopic submucosal dissection (ESD) commonly occurs within 3 days, but it may also occur after 1 week following ESD, especially in antiplatelet agent users. We evaluated the risk of delayed bleeding in post-ESD ulcers using the Forrest classification. Methods:Registry ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl16232
更新日期:2017-07-15 00:00:00
abstract::Cell death is now reclassified into several types based on the mechanisms and morphologic phenotype. Understanding of such classifications offers insights into the pathogenesis of liver disease, as well as diagnostic or therapeutic implications. Apoptosis is recognized relatively easily due to its unique morphology, b...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl18486
更新日期:2020-01-15 00:00:00
abstract:BACKGROUND/AIMS:To investigate the incidence of cholangiocarcinoma in patients with hepatolithiasis with or without previous resection of liver. METHODS:From 2002 to 2009, we retrospectively reviewed 117 patients who were diagnosed and treated for hepatolithiasis in Korea University Guro Hospital. Among the 117 patien...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.4.475
更新日期:2013-07-01 00:00:00
abstract:Background/Aims:We evaluated whether anti-Saccharomyces cerevisiae antibody (ASCA) titers are associated with diagnostic findings, disease activity, Paris classification phenotypes, and persistence after infliximab (IFX) treatment in children with Crohn's disease (CD). We also investigated the role of ASCA as a predict...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl20212
更新日期:2020-12-30 00:00:00
abstract::Inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, are chronic inflammatory conditions affecting the gastrointestinal tract with variable presentations and disease courses. The cause of IBD is unknown, but it is hypothesized that individuals with a genetic predisposition to disease deve...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl15491
更新日期:2016-07-15 00:00:00
abstract::We report herein three cases of inflammatory myoglandular polyp (IMGP) presenting as hematochezia. The polyps had pedunculated, red, and smooth features, and were 12, 12, and 15 mm in diameter and located in the sigmoid colon, transverse colon, and rectum, respectively. Endoscopic polypectomies were performed. Histolo...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2010.4.1.146
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND/AIMS:Obstruction of the main pancreatic duct (MPD) has been considered one of the major causes for pain in chronic pancreatitis (CP). In this study, we evaluated the efficacy of MPD stenting in painful CP, and tried to determine a guideline for stent removal. METHODS:Sixteen patients with painful CP who und...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2007.1.1.63
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND/AIMS:We aimed to assess the effectiveness of self-expanding metal stent (SEMS) insertion by evaluating the learning curve in relation to the experience of an endoscopist. METHODS:We retrospectively analyzed the outcomes of 120 SEMS insertion procedures performed by one endoscopist in patients with malignant...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2012.6.3.328
更新日期:2012-07-01 00:00:00
abstract:Background/Aims:The present study aimed to evaluate the safety and efficacy of simeprevir-based triple therapy with reduced doses of pegylated interferon (PEG-IFN) and ribavirin for interferon (IFN) ineligible patients, such as elderly and/or cirrhotic patients, and to elucidate the factors contributing to a sustained ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl16525
更新日期:2017-07-15 00:00:00
abstract:Background/Aims:Noninvasive liver fibrosis evaluation was performed in patients with nonalcoholic fatty liver disease (NAFLD). We used a quantitative method based on the hepatic volume acquired from gadoxetate disodium-enhanced (Gd-EOB-DTPA-enhanced) magnetic resonance imaging (MRI) for diagnosing advanced fibrosis in ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl16440
更新日期:2017-09-15 00:00:00
abstract::Enteropathy-type T-cell lymphoma (ETL) or enteropathy-associated T-cell lymphoma is a very rare malignant intestinal tumor. ETL is usually diagnosed by surgery. Endoscopic findings of ETL are not well known, and there are few reports of findings from endoscopy that has been performed only using white light. Additional...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2012.6.4.516
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND/AIMS:We aimed to investigate the relation-ships among various mutations of the p53 gene and their protein products, histological characteristics, and disease prognosis of primary colorectal cancer in Isfahan, central Iran. METHODS:Sixty-one patients with colorectal adenocarcinoma were enrolled in the study....
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.3.295
更新日期:2013-05-01 00:00:00
abstract:Background/Aims:Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA; EUS-FNA) allows for diagnostic tissue specimens from various regions to be analyzed. However, diagnosing recurrent pancreaticobiliary cancer after surgery is sometimes difficult. We evaluated the efficacy of EUS-FNA in the diagnosis of loca...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl19200
更新日期:2020-09-15 00:00:00
abstract::Hepatocellular carcinoma (HCC) is the fifth most common cancer globally and the fourth most common cancer in men in Korea, where the prevalence of chronic hepatitis B infection is high in middle-aged and elderly patients. These practice guidelines will provide useful and constructive advice for the clinical management...
journal_title:Gut and liver
pub_type: 杂志文章,实务指引
doi:10.5009/gnl19024
更新日期:2019-05-15 00:00:00
abstract::During the past few decades, liver transplant has developed from a high-mortality procedure to an almost routine procedure with good survival outcomes. The development of living donor liver transplant has increased the availability of liver grafts, and the scope of indications for liver transplant has been expanding e...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl19265
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND/AIMS:This study was performed to determine the association between RUNX3 expression and Helicobacter pylori infection in premalignant gastric lesions. METHODS:We examined 107 patients with gastric epithelial dysplasia who had undergone endoscopic mucosal resection or submucosal dissection. All tissue sample...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.6.688
更新日期:2013-11-01 00:00:00
abstract::The management of Helicobacter pylori infection in Singapore remains a clinical challenge. Similar to other regions, there has been an increase in antibiotic resistance rates through the years. Nonetheless, over the past two decades, clarithromycin-based triple therapy has continued to be used as the first line treatm...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl19308
更新日期:2021-01-15 00:00:00
abstract:Background/Aims:Chronic hepatitis C (CHC) is a major comorbidity in patients with hemophilia. Methods:Patients (n=30) were enrolled between September 2015 and April 2016. Twenty-six patients were genotype 1 (1b, n=21; 1a, n=5) and four patients were genotype 2a/2b. Among 21 patients with genotype 1b, Y93H resistance-a...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl17209
更新日期:2017-09-15 00:00:00
abstract:BACKGROUND/AIMS:Cytapheresis (CAP) is a novel strategy for ulcerative colitis (UC). However, there is insufficient data on the long-term outcome of UC patients who achieve remission by CAP. This study involved patients with severe UC who refracted to intravenous (iv) corticosteroid. METHODS:Forty-seven UC patients who...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2009.3.1.41
更新日期:2009-03-01 00:00:00
abstract:Background/Aims:The presence of invasion is a diagnostic criterion of early gastric cancer (EGC) in Korea, whereas diagnosis in Japan is based on enlarged nuclei and prominent nucleoli. Moreover, the depth of invasion is the location of cancer cell infiltration in Korea, whereas it is the location of lymphovascular inv...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl16281
更新日期:2017-05-15 00:00:00
abstract:BACKGROUND/AIMS:Standard treatments are not available for hilar nonresectable cholangiocarcinoma (NCC). It is unknown whether combination therapy of photodynamic therapy (PDT) plus systemic chemotherapy is superior to PDT alone. METHODS:We retrospectively reviewed 68 patients with hilar NCC treated with either PDT plu...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl15175
更新日期:2016-05-23 00:00:00
abstract:BACKGROUND/AIMS:We evaluated the characteristics of the National Cancer Screening Program (NCSP) and opinions regarding the National Endoscopy Quality Improvement Program (NEQIP). METHODS:We surveyed physicians performing esophagogastroduodenoscopy and/or colonoscopy screenings as part of the NCSP via e-mail between J...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl15623
更新日期:2016-09-15 00:00:00
abstract:Background/Aims:Although many studies have reported the promising effect of neoadjuvant treatment for borderline resectable pancreatic cancer (BRPC) to increase resectability, only a few studies have recommended the use of firstline chemotherapeutic agents as neoadjuvant treatment for BRPC. The current study compared c...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl20070
更新日期:2020-08-26 00:00:00
abstract::Serrated polyps are considered precursor lesions that account for 15% to 30% of colorectal cancers, and they are overrepresented as a cause of interval cancers. They are difficult to detect and resect comprehensively; however, recent data suggest that high definition endoscopy, chromoendoscopy (via spray catheter, pum...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl19202
更新日期:2020-07-15 00:00:00
abstract:BACKGROUND/AIMS:Small core biopsy samples can occasionally be obtained with conventional endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA). Although most studies have focused on the cytological analysis of specimens, data regarding histological assessment is scarce. The aim of this study was to determi...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl.2013.7.5.605
更新日期:2013-09-01 00:00:00
abstract:Background/Aims:Although gastric cancer (GC) prevalence in the United States overall is low, there is significantly elevated risk in certain racial/ethnic groups. Providers caring for high-risk populations may not be fully aware of GC risk factors and may underestimate the potential for selective screening. Our aim was...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl17091
更新日期:2018-01-15 00:00:00
abstract:BACKGROUND/AIMS:Several precut techniques have been used to gain biliary access for difficult cases. The aim of this study was to evaluate the success and complication rates of two precut techniques, transpancreatic septotomy (TPS) and needle knife infundibulotomy (NKI), in difficult biliary cannulation due to the pres...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl14223
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND/AIMS:To determine factors predictive of discordance in staging liver fibrosis using liver biopsy (LB) and acoustic radiation force impulse (ARFI) elastography in patients with chronic hepatitis B (CHB). METHODS:Consecutive patients with CHB who underwent LB and ARFI elastography on the same day from Novembe...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl14391
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND/AIMS:In patients with corticosteroid-refractory ulcerative colitis (UC), cyclosporine or infliximab may be added to the treatment regimen to induce remission. Here, we aimed to compare the efficacy of cyclosporine and infliximab. METHODS:Between January 1995 and May 2012, the medical records of 43 patients ...
journal_title:Gut and liver
pub_type: 杂志文章
doi:10.5009/gnl14120
更新日期:2015-09-23 00:00:00
abstract::This systematic review aimed to assess the efficacy of the current approach to tissue traction during the endoscopic submucosal dissection (ESD) of superficial esophageal cancer, early gastric cancer, and colorectal neoplasms. We performed a systematic electronic literature search of articles published in PubMed and s...
journal_title:Gut and liver
pub_type: 杂志文章,评审
doi:10.5009/gnl19266
更新日期:2020-11-15 00:00:00