Azole resistance in Candida albicans from animals: Highlights on efflux pump activity and gene overexpression.

abstract：:Zygomycoses are very rare invasive fungal infections (IFI). They primarily occur in the immunocompromised patients and are associated with a high mortality. During the last years, a rising incidence of zygomycosis in patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT) has been reported, whic...

journal_title：Mycoses

authors： Glöckner A,Vehreschild JJ,Cornely OA

更新日期：2007-01-01 00:00:00

abstract：:The prevalence of atopic dermatitis (AD) has been increasing. Whereas AD symptoms are obvious and easy to recognise, the etiopathogenesis remains not fully elucidated. Recently, the role of microorganisms and their impact on the immunology of AD have been discussed. In this review, we summarise a possible role of Mala...

journal_title：Mycoses

authors： Nowicka D,Nawrot U

更新日期：2019-07-01 00:00:00

abstract：:Over-expression of multidrug efflux transporters causes Candida albicans cells to be resistant to azole antifungal agents. There are several kinds of indicator for multidrug resistance (MDR) phenotype of higher eukaryotic cells. Calcein AM is a prefluorochrome that is known as a substrate for multidrug efflux transpor...

journal_title：Mycoses

authors： Yang HC,Mikami Y,Imai T,Taguchi H,Nishimura K,Miyaji M,Branchini ML

更新日期：2001-11-01 00:00:00

abstract：:In Japan, Trichophyton tonsurans infection has become an increasing problem among combat sports participants. We investigated the prevalence of T. tonsurans infection in athletes affiliated to judo clubs in the 21 First Division universities that were registered with the University Judo Federation of Tokyo in 2008. St...

journal_title：Mycoses

authors： Hirose N,Suganami M,Ogawa YS,Hiruma M,Ogawa H

更新日期：2011-07-01 00:00:00

abstract：:Invasive fungal disease (IFD) causes increasing morbidity and mortality in haematological cancer patients. Reliable cost data for treating IFD in German hospitals is not available. Objective of the study was to determine the institutional cost of treating the IFD. Data were obtained by retrospective chart review in Ge...

journal_title：Mycoses

authors： Rieger CT,Cornely OA,Hoppe-Tichy T,Kiehl M,Knoth H,Thalheimer M,Schuler U,Ullmann AJ,Ehlken B,Ostermann H

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Clioquinol was used in the 1950s-1970s as antimicrobial but its oral formulations were withdrawn from the market due to suspected neurotoxicity. Currently, there is possibility of repositioning of oral clioquinol formulations. OBJECTIVES:To evaluate the antifungal activity and toxicological parameters of cl...

journal_title：Mycoses

authors： Pippi B,Merkel S,Staudt KJ,Teixeira ML,de Araújo BV,Zanette RA,Andrade SF,Fuentefria AM

更新日期：2019-05-01 00:00:00

abstract：:Accurate identification of fungal pathogens using a sequence-based approach requires an extraction method that yields template DNA pure enough for polymerase chain reaction (PCR) or other types of amplification. Therefore, the objective of this study was to develop and standardise a rapid, inexpensive DNA extraction p...

journal_title：Mycoses

authors： Romanelli AM,Fu J,Herrera ML,Wickes BL

更新日期：2014-10-01 00:00:00

abstract：:During the last decade cryptococcoses were most frequently diagnosed in AIDS patients, where serologically high amounts of glucoronoxylomannan (GXM) were detectable. Disseminated cryptococcoses without cryptococcal antigen detection is unusual. Between August and October 1998 disseminated cryptococcoses were diagnosed...

journal_title：Mycoses

authors： Tintelnot K,Adler S,Bergmann F,Schönherr K,Seibold M

更新日期：2000-01-01 00:00:00

abstract：:To describe the epidemiology of invasive Candida infection in a tertiary care paediatric hospital. Prospective single-centre survey on all Candida strains isolated from normally sterile fluids and urines in the period 2005-2015 . A total of 299 ICI were documented in 262 patients. Urinary tract infection represented t...

journal_title：Mycoses

authors： Mesini A,Bandettini R,Caviglia I,Fioredda F,Amoroso L,Faraci M,Mattioli G,Piaggio G,Risso FM,Moscatelli A,Loy A,Castagnola E

更新日期：2017-02-01 00:00:00

abstract：:The purpose of this study was to investigate the interaction between intravenous ampicillin-sulbactam treatment and (1,3)-beta-D-glucan (BDG) assay. Fifteen patients with a median age of 60 (16-81) without known risk factors for invasive fungal infections who received a daily dose of 3×2g ampicillin-sulbactam monother...

journal_title：Mycoses

authors： Metan G,Agkus C,Nedret Koc A,Elmali F,Finkelman MA

更新日期：2012-07-01 00:00:00

abstract：:This study sought to determine the prevalence of skin infections and their causative agents in the Libyan population. Samples were collected from 2224 patients attending the Dermatology Clinics of the Tripoli Medical Centre (TMC) between August 1997 and December 1999 and were submitted to a mycology laboratory for ana...

journal_title：Mycoses

authors： Ellabib MS,Khalifa Z,Kavanagh K

更新日期：2002-04-01 00:00:00

abstract：:The annual incidence of cryptococcosis during 1981-2000 was determined in subscribers of a large integrated health care program in Northern California and in those among them who were HIV positive. The incidence of cryptococcosis had been measured in this setting in the previous decade. The 20-year incidence per milli...

journal_title：Mycoses

authors： Friedman GD,Jeffrey Fessel W,Udaltsova NV,Hurley LB

更新日期：2005-03-01 00:00:00

abstract：:Due to the Fourier-Transform Infrared Spectroscopy (FT-IR) of strain specific traits demonstrated to be a suitable and efficient method for diagnostic and epidemiological determinations for the yeasts Candida albicans, Exophiala dermatitidis and the chlorophylless algae of the genus Prototheca. FT-IR leads in a rapid ...

journal_title：Mycoses

authors： Schmalreck AF,Tränkle P,Vanca E,Blaschke-Hellmessen R

更新日期：1998-01-01 00:00:00

abstract：:Here, a microdilution technique based on the M27-A2 protocol (NCCLS, 2002) was employed to compare the susceptibilities of Candida albicans and Candida dubliniensis to essential oils extracted from plants used as spices. The chemical compositions of the essential oils were defined based on the analysis of retention in...

journal_title：Mycoses

authors： Pozzatti P,Loreto ES,Lopes PG,Athayde ML,Santurio JM,Alves SH

更新日期：2010-01-01 00:00:00

abstract：:Although conventional identification of pathogenic fungi is based on the combination of tests evaluating their morphological and biochemical characteristics, they can fail to identify the less common species or the differentiation of closely related species. In addition these tests are time consuming, labour-intensive...

journal_title：Mycoses

authors： Kiraz N,Oz Y,Aslan H,Erturan Z,Ener B,Akdagli SA,Muslumanoglu H,Cetinkaya Z

更新日期：2015-10-01 00:00:00

abstract：:Candida albicans is the fourth most germ that can be identified on surgical intensive care unit (SICU). During the course of severe peritonitis recognition of Candida is crucial for physicians but interpretation of Candida-positive microbiologic samples is difficult. The indication for antimycotic therapy requires dif...

journal_title：Mycoses

authors： Kujath P,Bouchard R,Nolde J,Scheele J

更新日期：2005-01-01 00:00:00

abstract：:Eight cases of imported mycetomata in The Netherlands are reviewed. Seven of these were cultured; only one isolate, Actinomadura madurae, belonged to a species commonly known as an agent of mycetoma. The remaining strains either belonged to very rare species, such as Phialophora cyanescens, or could not be identified ...

journal_title：Mycoses

authors： de Hoog GS,Buiting A,Tan CS,Stroebel AB,Ketterings C,de Boer EJ,Naafs B,Brimicombe R,Nohlmans-Paulssen MK,Fabius GT

更新日期：1993-03-01 00:00:00

abstract：:Regulation of morphogenesis through the production of chemical signalling molecules such as isoamyl alcohol, 2-phenylethyl alcohol, 1-dodecanol, E-nerolidol and farnesol is reported in Candida albicans. The present study focuses on the effect of ethyl alcohol on C. albicans dimorphism and biofilm development. Ethyl al...

journal_title：Mycoses

authors： Chauhan NM,Raut JS,Karuppayil SM

更新日期：2011-11-01 00:00:00

abstract：:Pneumocystosis (PCP) mortality in the U.S. has received less attention in recent years. This study describes recent trends in mortality and the estimated burden of PCP in the U.S., using the national multiple cause of death data during 1999-2014. PCP mortality rates were calculated for age, sex, race and year. Demogra...

journal_title：Mycoses

authors： Wickramasekaran RN,Jewell MP,Sorvillo F,Kuo T

更新日期：2017-09-01 00:00:00

abstract：:A universal PCR-assay for the detection of fungal DNA was compared with microscopy and culture for the diagnosis of invasive aspergillosis using 78 samples from 42 patients. Eighteen patients were suffering from invasive aspergillosis, 5 patients were colonized with Aspergillus in the respiratory tract, 19 patients di...

journal_title：Mycoses

authors： Rimek D,Garg AP,Kappe R,Sonntag HG

更新日期：1998-01-01 00:00:00

abstract：:Chronic vegetating pyoderma is usually associated with staphylococci and streptococci. A case that started as a therapeutically resistant tinea of the hand caused by Trichophyton mentagrophytes is described. The vegetating skin lesion was associated with low immunoglobulin levels and impaired phagocytosis. It healed a...

journal_title：Mycoses

authors： Skorepová M,Stuchlík D

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Acute myeloid leukaemia (AML) patients are at high risk of invasive aspergillosis (IA) after first induction chemotherapy (CHT). Although IA risk factors have been identified, few data are available on impact of IA, occurring during induction phase, on overall AML outcome. PATIENTS AND RESULTS:The end point...

journal_title：Mycoses

authors： Candoni A,Farina F,Perruccio K,Di Blasi R,Criscuolo M,Cattaneo C,Delia M,Zannier ME,Dragonetti G,Fanci R,Martino B,Del Principe MI,Fianchi L,Vianelli N,Chierichini A,Garzia M,Petruzzellis G,Nadali G,Verga L,Busca A

更新日期：2020-10-01 00:00:00

abstract：:Comparative studies were performed to assess the stability and lot-to-lot variation of Blastomyces dermatitidis yeast and mycelial phase lysate antigens. Four lots were prepared from each growth phase of B. dermatitidis strain T-58 (canine isolate) during a 14-month period. Serum specimens from dogs with blastomycosis...

journal_title：Mycoses

authors： Orr ML,Bono JL,Abuodeh RO,Williams SJ,Legendre AM,Scalarone GM

更新日期：1994-06-01 00:00:00

abstract：:Dermatophyte infections, while not life-threatening, are very common, and there is great interest in developing new antifungal agents. Transcriptional profiling of Trichophyton on keratin has identified some antioxidant genes as induced on this host substrate, including a thioredoxin gene TmTRX1. If thioredoxin is a v...

journal_title：Mycoses

authors： Berdicevsky I,Kaufman G,Newman DJ,Horwitz BA

更新日期：2009-07-01 00:00:00

abstract：:Mucormycosis, previously termed as zygomycosis, is caused by fungi belonging to the order Mucorales and is a very severe disease in immunocompromised patients with an often unfavourable outcome. Given the high morbidity and mortality of mucormycosis, establishing a timely diagnosis followed by immediate treatment is o...

journal_title：Mycoses

authors： Tacke D,Koehler P,Markiefka B,Cornely OA

更新日期：2014-09-01 00:00:00

abstract：:A 45-year-old woman was found to have cerebral phaeohyphomycosis caused by an Exophiala species. The portal of entry of the fungus remained unknown. Despite surgery and antimycotic therapy the patient died from circulation failure. The fungus is compared to several related Exophiala species. ...

journal_title：Mycoses

authors： Tintelnot K,de Hoog GS,Thomas E,Steudel WI,Huebner K,Seeliger HP

更新日期：1991-05-01 00:00:00

abstract：:This paper reports a case of chronic necrotizing pulmonary aspergillosis in a patient without underlying disease. Aspergilluria was the starting point in the search for the origin of the pulmonary disease, later confirmed by an open lung biopsy. ...

journal_title：Mycoses

authors： Lopes JO,Oliveira LT,Pinto MS,Klock C

更新日期：1997-10-01 00:00:00

abstract：:The observation of a considerable incidence of fungal infections in oncology patients has promoted a large number of studies both on prophylaxis and treatment in this patient group. Trials using triazoles, especially fluconazole, have shown effect in preventing fungal infections. In neutropenic patients, their role in...

journal_title：Mycoses

authors： Schuler U,Mölle M,Ehninger G

更新日期：1995-01-01 00:00:00

abstract：:Candida wangnamkhiaoensis is a species clustered under the Hyphopichia clade has not ever been isolated from any clinical specimens. To the best of our knowledge, this is the first report of C. wangnamkhiaoensis associated with fungaemia in immunocompromised paediatric patient. The isolate was assigned a strain name a...

journal_title：Mycoses

authors： Tap RM,Ho Betty LS,Ramli NY,Suppiah J,Hashim R,Sabaratnam P,Ginsapu SJ,Gowbei A,Razak MF,Sipiczki M,Ahmad N

更新日期：2016-11-01 00:00:00

abstract：:Trichophyton rubrum, T. mentagrophytes, T. verrucosum, Microsporum canis, M. gypseum and Epidermophyton flocoosum represent the cause of human dermatomycoses isolated most often at the University Hospital of Dermatology in Graz, Austria, between 1991 and 1998. So far, identification was mainly based on the cultivation...

journal_title：Mycoses

authors： Blanz P,Buzina W,Ginter G,Gräser Y

更新日期：2000-01-01 00:00:00